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Preventable Readmissions Within 30 Days of Ischemic Stroke Among Medicare Beneficiaries Clinical Sciences
Conclusions— On the basis of Agency for Healthcare Research and Quality Prevention Quality Indicators, we found that a small proportion of readmissions after ischemic stroke were classified as preventable. Although other causes of readmissions not reflected in the Agency for Healthcare Research and Quality measures could also be avoidable, hospital-level programs intended to reduce all-cause readmissions and costs should target high-risk patients.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Lichtman, J. H., Leifheit-Limson, E. C., Jones, S. B., Wang, Y., Goldstein, L. B. Tags: Clinical Sciences Source Type: research

Biomarkers and Mortality After Transient Ischemic Attack and Minor Ischemic Stroke: Population-Based Study Clinical Sciences
Conclusions— Several biomarkers predicted death of any cause after transient ischemic attack and minor stroke. N-terminal pro-B-type natriuretic peptide and heart-type fatty-acid-binding protein might improve patient selection for additional screening for occult cardiac disease or cancer, respectively. However, our results require validation in future studies.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Greisenegger, S., Segal, H. C., Burgess, A. I., Poole, D. L., Mehta, Z., Rothwell, P. M. Tags: Epidemiology Clinical Sciences Source Type: research

Circulating Tissue Factor Levels and Risk of Stroke: Findings From the EPICOR Study Clinical Sciences
Conclusions— Our data provide evidence that elevated levels of circulating TF are potential risk factors for ischemic strokes.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Iacoviello, L., Di Castelnuovo, A., de Curtis, A., Agnoli, C., Frasca, G., Mattiello, A., Matullo, G., Ricceri, F., Sacerdote, C., Grioni, S., Tumino, R., Napoleone, E., Lorenzet, R., de Gaetano, G., Panico, S., Donati, M. B. Tags: Risk Factors, Coagulation, Acute Cerebral Hemorrhage Clinical Sciences Source Type: research

Risk of Ischemic Stroke and Major Bleeding in Patients With Atrial Fibrillation and Cancer
Background: Atrial fibrillation (AF) is an important risk factor for ischemic stroke. Cancer may increase the risk both of ischemic stroke and of bleeding. Less is known about risk of ischemic stroke and bleeding among cancer patients with AF, complicating the prevention of ischemic stroke in these patients. Methods: Register based cohort study comprising all Swedish patients hospitalized with a primary diagnosis of AF from July 1, 2005 until December 31, 2014. Patients with cancer diagnosis were compared to the rest of the cohort.
Source: Journal of Stroke and Cerebrovascular Diseases - December 26, 2019 Category: Neurology Authors: Sara Aspberg, Liyang Yu, Bruna Gigante, Karin E Smedby, Daniel E Singer Source Type: research

Cancer and Tumor-Associated Childhood Stroke: Results from the International Pediatric Stroke Study
This study sought to evaluate cancer/tumor-associated childhood ischemic stroke in a multinational pediatric stroke registry.
Source: Pediatric Neurology - June 8, 2020 Category: Neurology Authors: Lisa R. Sun, Alexandra Linds, Mukta Sharma, Mubeen Rafay, Sudhakar Vadivelu, Sarah Lee, Leonardo R. Brand ão, Brian Appavu, Jeremie H. Estepp, Juliette Hukin, Sahar M.A. Hassanein, Anthony Chan, Lauren A. Beslow, International Pediatric Stroke Study Grou Tags: Research Paper Source Type: research

The Risk Factors for Death within 6 Months After Ischemic Stroke in Patients with Cancer
While the intravenous recombinant tissue plasminogen activator (rt-PA) therapy for acute ischemic stroke patients with cancer is recommended when survival of ≥ 6 months is expected, the risk factors for death and stroke recurrence within 6 months after stroke are not well known. Thus, we aimed to identify markers for death and recurrence risks within six months from stroke onset in patients with cancer.
Source: Journal of Stroke and Cerebrovascular Diseases - October 16, 2020 Category: Neurology Authors: Yoko Tsuchihashi, Takahiro Shimizu, Hisanao Akiyama, Yuta Hagiwara, Kaima Soga, Naoki Takao, Kenji Uchino, Toshiyuki Yanagisawa, Junji Yamauchi, Tomoo Sato, Yasuhiro Hasegawa, Yoshihisa Yamano Source Type: research

Understanding Coordinator Roles in Acute Stroke Care: A National Survey
Globally, stroke is a major contributor to death and disability.1 Evidence-based care in hospital after an acute stroke ensures improved survival and reduced disability, but care quality can vary.2,3 Clinical coordinators have an essential role in improving best-practice in trauma, cancer, diabetes, and heart failure conditions.4-7 Within stroke, coordinator roles are not new; in 1970, a study outlining the ‘Stroke Team’ model was published, which included a physician, nurse-coordinator and physical therapist.
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2021 Category: Neurology Authors: Tara Purvis, Sandy Middleton, Anne W. Alexandrov, Monique F. Kilkenny, Skye Coote, Sarah Kuhle, Dominique A. Cadilhac Source Type: research

A stroke mimic; focal neurological deficits in benign hereditary chorea?
Conclusion This case highlights the difficulties in assessing patients with new focal neurological symptoms in the presence of known, pre existing, neurological disease. It also serves to highlight how often erroneously progressive weakness is mislabelled as a ‘stroke’. Neurologists working together with acute physicians in liaison posts in MAU, provides a unique opportunity to improve overall recognition of neurological disease, and for patients potentially provides a more timely diagnostic work–up and the opportunity for early treatment.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 9, 2013 Category: Neurosurgery Authors: Maw, K., Johnston, J., Rowntree, C., Kalhan, A. Tags: Immunology (including allergy), Headache (including migraine), Movement disorders (other than Parkinsons), Neurooncology, Pain (neurology), Stroke, CNS cancer, Neuropathology, Radiology, Surgical diagnostic tests, Surgical oncology Association of Britis Source Type: research

Treatment of Cryptogenic Stroke with Active Cancer with a New Oral Anticoagulant
Low-molecular weight heparin (LMWH) was shown to be effective and safe in treating venous thromboembolism, and generally used for stroke in cancer patients, but its effects on stroke are unclear. We compared clinical outcomes between LMWH and new oral anticoagulant (NOAC) in patients with cancer-related stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 23, 2017 Category: Neurology Authors: Ki-Woong Nam, Chi Kyung Kim, Tae Jung Kim, Sang Joon An, Kyungmi Oh, Sang-Bae Ko, Byung-Woo Yoon Source Type: research

Determination of Clinical Cut-Off Values for Serum Cystatin C Levels to Predict Ischemic Stroke Risk
Background: The association between cystatin C and risk of ischemic stroke is inconsistent and the cut-off values of cystatin C are diverse in different articles. We aimed to investigate the association between cystatin C levels and the development of ischemic stroke and to explore the clinical cut-off values of serum cystatin C levels for ischemic stroke. Methods: This prospective cohort study included 7658 participants from the China Health and Retirement Longitudinal Study who were free of cardiovascular diseases and cancer at baseline.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2019 Category: Neurology Authors: Youyi Wang, Ying Zhang, Qinghua Ma, Congju Wang, Yong Xu, Hongpeng Sun, Yana Ma Source Type: research

Ability of the number of territories involved on dwi-mri to predict occult systemic malignancy in cryptogenic stroke patients
Lesions in multiple arterial territories is one of the typical features of malignancy patients with cryptogenic stroke. Hence, if patients with cryptogenic stroke display such feature, occult cancer could be predicted. The study aimed to analyze the predictive ability of the number of territories involved on DWI-MRI for occult systemic malignancy (OSM) in patients with cryptogenic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - April 29, 2020 Category: Neurology Authors: Linjia Guo, Lili Wang, Wenhong Liu Source Type: research

Clinical Characteristics and Analysis of Lung Cancer- Associated Acute Ischemic Stroke
The incidence of lung cancer and acute ischemic stroke remains high in recent years, both of which occur mostly in people over 60 years old. In the present study, we aimed to further clarify the pathogenesis of lung cancer-associated acute ischemic stroke (LCA-AIS) by comparing and analyzing clinical characteristics of stroke patients with or without lung cancer.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Jing Zhang, Jingxia Zhao Source Type: research

Endovascular Therapy of Acute Ischemic Stroke in Patients with Large-Vessel Occlusion Associated with Active Malignancy
Approximately 15% of cancer patients have concomitant cerebrovascular disease.1,2 The frequency of ischemic and hemorrhagic stroke in this group of patients is similar to the general population2, and about one in ten stroke patients may have a concurrent malignancy.3 Intravenous thrombolysis (IVT) in these patients is often contraindicated and is used less frequently due to various possible comorbidities.4 While EVT is a well-established approach to treat acute ischemic stroke (AIS) secondary to large vessel occlusion (LVO) 5,6,7,8, there is paucity of data with regards to EVT success and outcomes in patients with active malignancy.
Source: Journal of Stroke and Cerebrovascular Diseases - November 24, 2020 Category: Neurology Authors: Tomohiko Ozaki, Patrick Nicholson, Joanna D. Schaafsma, Ronit Agid, Timo Krings, Aleksandra Pikula, Vitor Mendes Pereira Source Type: research

Elevated CA125 is Related to Stroke Due to Cancer- Associated Hypercoagulation
It is well-known that cancer patients commonly have ischemic stroke and the incidence is getting increased with the development of cancer therapy prolonging survival.1 Ischemic stroke in cancer patients is caused by various etiologies. Cancer-associated hypercoagulation is one of the major important pathophysiological mechanisms of stroke in cancer patients.2,3 This hypercoagulation is mediated by multiple mechanisms associated with tissue factor, mucin, and cysteine proteinase. Carcinomatous mucins are considered to trigger thrombogenicity by interacting with P and L selectins and inducing the formation of platelet-rich microthrombi.
Source: Journal of Stroke and Cerebrovascular Diseases - September 27, 2021 Category: Neurology Authors: Keiko Maezono-Kandori, Tomoyuki Ohara, Jun Fujinami, Naoki Makita, Eijirou Tanaka, Toshiki Mizuno Source Type: research

Endovascular Treatment for Acute Ischemic Stroke After Video-Assisted Thoracoscopic Pulmonary Lobectomy in Patients With Lung Cancer: A Report of Four Cases and Literature Review
Postoperative cerebral embolic stroke is a serious complication of pulmonary lobectomy, occurring in 1.1% of patients undergoing lobectomy through video-assisted thoracoscopic surgery (VATS). The mechanism of this complication is thought to be embolic stroke caused by thrombus formed due to stagnation in the pulmonary vein stump after VATS lobectomy. There have been few reports demonstrating the utility of endovascular treatment (EVT) for cerebral embolic stroke after VATS lobectomy.
Source: Journal of Stroke and Cerebrovascular Diseases - June 10, 2022 Category: Neurology Authors: Hiroshi Ueno, Hiroto Yamaoka, Sakyo Hirai, Kyohei Fujita, Mariko Ishikawa, Shoko Fujii, Yuki Aizawa, Yosuke Ishii, Masataka Yoshimura, Kenji Yamada, Yoshikazu Yoshino, Morito Kurata, Katsutoshi Seto, Hironori Ishibashi, Kenichi Okubo, Shigeru Nemoto, Kazu Tags: Case Report Source Type: research