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Nutrition: Sodium Chloride

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Total 383 results found since Jan 2013.

Sodium Handling and Interaction in Numerous Organs.
Abstract Salt (NaCl) is a prerequisite for life. Excessive intake of salt, however, is said to increase disease risk including hypertension, arteriosclerosis, heart failure, renal disease, stroke, and cancer. Therefore, considerable research has been expended on the mechanism of sodium handling based on the current concepts of sodium balance. The studies have necessarily relied on relatively short-term experiments and focused on extremes of salt intake in humans. Ultra-long-term salt balance has received far less attention. We performed long-term salt balance studies at intakes of 6, 9, and 12 g/day and found that...
Source: American Journal of Hypertension - March 20, 2020 Category: Cardiology Authors: Minegishi S, Luft FC, Titze J, Kitada K Tags: Am J Hypertens Source Type: research

Janssen Highlights Continued Commitment to Cardiovascular & Metabolic Healthcare Solutions with Late-Breaking Data at the First Fully Virtual American College of Cardiology Scientific Session
RARITAN, N.J., March 20, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that it will unveil late-breaking data from its leading cardiovascular and metabolism portfolio during the virtual American College of Cardiology’s 69th Annual Scientific Session together with the World Congress of Cardiology (ACC.20/WCC) on March 28-30, 2020. Notably, four late-breaking abstracts for XARELTO® (rivaroxaban) will be presented, including data from the Phase 3 VOYAGER PAD study in patients with symptomatic peripheral artery disease (PAD) after lower-extremity revascularization.Click to Tweet: Jan...
Source: Johnson and Johnson - March 20, 2020 Category: Pharmaceuticals Source Type: news

The hypotensive effect of salt substitutes in stage 2 hypertension: a systematic review and meta-analysis
Hypertension (HTN) is a ubiquitous risk factor for numerous non-communicable diseases, including cardiovascular disease and stroke. There are currently no wholly effective pharmacological therapies for subject...
Source: BMC Cardiovascular Disorders - February 27, 2020 Category: Cardiology Authors: Sadegh Jafarnejad, Hamed Mirzaei, Cain C. T. Clark, Mohsen Taghizadeh and Armin Ebrahimzadeh Tags: Research article Source Type: research

Excess salt intake promotes M1 microglia polarization via a p38/MAPK/AR-dependent pathway after cerebral ischemia in mice.
In conclusion, HSD promotes polarization in pro-inflammatory M1 microglia by upregulating the expression of the AR protein via p38/MAPK, thereby exacerbating the development of ischemia stroke. PMID: 32044667 [PubMed - as supplied by publisher]
Source: International Immunopharmacology - February 6, 2020 Category: Allergy & Immunology Authors: Zhang T, Wang D, Li X, Jiang Y, Wang C, Zhang Y, Kong Q, Tian C, Dai Y, Zhao W, Jiang M, Chang Y, Wang G Tags: Int Immunopharmacol Source Type: research

Sodium reduction in Turkey breast meat by using sodium anion species
This study aims at reducing the overall sodium content in turkey meat application by using alternative sodium species. Initial experiments studied the sodium absorption across the temperature range of 4 to 90 °C which showed higher sodium content for thermally processed samples over a longer cooking time. Overall, the adsorption rate was found to be slower and was not affected by protein denaturation. Additional experiments studied the sodium diffusion by replacing sodium chloride with alternative sodium salts with comparatively larger anions, which resulted in, 20–46% reduction in overall sodium content of thermally ...
Source: LWT Food Science and Technology - February 4, 2020 Category: Food Science Source Type: research

A novel dried blood spots analysis combined with on-spot reaction for determination of trimethylamine N-oxide and its related compounds.
Abstract The application of dried blood spots in clinical research is becoming increasingly popular owing to its convenient collection, storage, and transportation compared to that of conventional biological samples. The potential of trimethylamine N-oxide and its related compounds as biomarkers for various cardiovascular diseases, such as atherosclerosis, stroke, thrombosis, and heart failure, was recently highlighted, which was the driving force behind the development of an analytical method to identify trimethylamine N-oxide and eight related compounds in dried blood spots. In the proposed method, a novel "on-s...
Source: Talanta - January 30, 2020 Category: Chemistry Authors: Cho HD, Kim J, Lee JY, Kim YY, Lee Y, Jo E, Suh JH, Lee J, Cha S, Han SB Tags: Talanta Source Type: research

Incidence, clinical characteristics, and risk factors of peripartum cardiomyopathy in Nigeria: results from the PEACE Registry
ConclusionsIn Nigeria, the burden of PPCM was greatest in the North –West zone, which has the highest known incidence. PPCM was predicted by sociodemographic factors and pre‐eclampsia, which should be considered in its control at population level. Postpartum customary birth practices and Hausa–Fulani ethnicity were not associated with PPCM in Nigeria.
Source: ESC Heart Failure - January 27, 2020 Category: Cardiology Authors: K.M. Karaye, N.A. Ishaq, H. Sa'idu, S.A. Balarabe, M.A. Talle, M.S. Isa, U.G. Adamu, H. Umar, H.I. Okolie, M.N. Shehu, I.Y. Mohammed, B. Sanni, O.S. Ogah, I. Oboirien, E.M. Umuerri, A.C. Mankwe, V.Y. Shidali, P. Njoku, S. Dodiyi ‐Manue Tags: Original Research Article Source Type: research

Is the reduction of salt in the bread consumed in Morocco could be a means of protection against cardiovascular diseases?
ConclusionThis study highlights the effectiveness of awareness campaigns through the KAP for reducing the use of salt in bread-making. Knowing that the daily consumption of bread in Morocco varied between 360 and 500 g, this reduction of 26.3% of the salt in the bread certainly has a very positive impact on the CVD protection.
Source: Archives of Cardiovascular Diseases Supplements - January 7, 2020 Category: Cardiology Source Type: research

Interim effects of salt substitution on urinary electrolytes and blood pressure in the China Salt Substitute and Stroke Study (SSaSS)
Publication date: Available online 7 January 2020Source: American Heart JournalAuthor(s): Liping Huang, Maoyi Tian, Jie Yu, Qiang Li, Yishu Liu, Xuejun Yin, Jason HY Wu, Matti Marklund, Yangfeng Wu, Nicole Li, Paul Elliot, Lijing L. Yan, Darwin R. Labarthe, Zhixin Hao, Jingpu Shi, Xiangxian Feng, Jianxin Zhang, Yuhong Zhang, Ruijuan Zhang, Bo ZhouAbstractThe Salt Substitute and Stroke Study is an ongoing 5-year large-scale cluster randomized trial investigating the effects of potassium-enriched salt substitute compared to usual salt on the risk of stroke. The study involves 600 villages and 20,996 individuals in rural Chin...
Source: American Heart Journal - January 7, 2020 Category: Cardiology Source Type: research

Mitochondrial Deacetylase Sirt3 Reduces Vascular Dysfunction and Hypertension While Sirt3 Depletion in Essential Hypertension Is Linked to Vascular Inflammation and Oxidative Stress.
Conclusions: We suggest that Sirt3 depletion in hypertension promotes endothelial dysfunction, vascular hypertrophy, vascular inflammation and end-organ damage. Our data support a therapeutic potential of targeting Sirt3 expression in vascular dysfunction and hypertension. PMID: 31852393 [PubMed - as supplied by publisher]
Source: Circulation Research - December 18, 2019 Category: Cardiology Authors: Dikalova AE, Pandey AK, Xiao L, Arslanbaeva L, Sidorova T, Lopez MG, Billings Iv FT, Verdin E, Auwerx J, Harrison DG, Dikalov SI Tags: Circ Res Source Type: research

Pharmacological restoration of autophagy reduces hypertension-related stroke occurrence.
Abstract The identification of the mechanisms predisposing to stroke may improve its preventive and therapeutic strategies in patients with essential hypertension. The role of macroautophagy/autophagy in the development of hypertension-related stroke needs to be clarified. We hypothesized that a defective autophagy may favor hypertension-related spontaneous stroke by promoting mitochondrial dysfunction. We studied autophagy in the stroke-prone spontaneously hypertensive (SHRSP) rat, which represents a clinically relevant model of stroke associated with high blood pressure. We assessed autophagy, mitophagy and NAD+...
Source: Autophagy - November 2, 2019 Category: Cytology Authors: Forte M, Bianchi F, Cotugno M, Marchitti S, De Falco E, Raffa S, Stanzione R, di Nonno F, Chimenti I, Palmerio S, Pagano F, Petrozza V, Micaloni A, Madonna M, Relucenti M, Torrisi MR, Frati G, Volpe M, Rubattu S, Sciarretta S Tags: Autophagy Source Type: research

IJERPH, Vol. 16, Pages 4151: Being Conscious of Water Intake Positively Associated with Sufficient Non-Alcohol Drink Intake Regardless of Seasons and Reasons in Healthy Japanese; the KOBE Study: A Cross Sectional Study
to Tomonori Okamura The present study sought to clarify if being conscious of water intake (CWI) is associated with sufficient non-alcohol drink (NAD) intake. We used data of healthy participants without diabetes, aged 40–74 years, in the Kobe Orthopedic and Biomedical Epidemiologic (KOBE) study. The association between being CWI and NAD intake was evaluated by multivariate linear regression analyses after adjusting for age, sex, surveyed months (seasons), alcohol drinking, health-awareness life habits, socioeconomic factors, serum osmolarity, estimated daily salt intake, and reasons for NAD intake. Amo...
Source: International Journal of Environmental Research and Public Health - October 27, 2019 Category: Environmental Health Authors: Tomofumi Nishikawa Naomi Miyamatsu Aya Higashiyama Yoshimi Kubota Yoko Nishida Takumi Hirata Daisuke Sugiyama Kazuyo Kuwabara Sachimi Kubo Yoshihiro Miyamoto Tomonori Okamura Tags: Article Source Type: research

Let Plants be Thy Medicine – You Are What You Eat
Credit: Busani Bafana/IPSBy Esther Ngumbi and Ifeanyi NsoforILLINOIS, United States / ABUJA, Oct 16 2019 (IPS) United Nations World Food Day is celebrated around the world on October 16 under the theme: “Our Actions ARE Our Future. Healthy Diets for a Zero Hunger World”. This theme is timely, especially, because across Africa and around the world, there has been a gradual rise in malnutrition and diet-related non communicable diseases, as highlighted in The Lancet study and a United Nations Report published earlier this year. While 45 percent of deaths in children are from nutrition-related causes, mainly malnu...
Source: IPS Inter Press Service - Health - October 16, 2019 Category: International Medicine & Public Health Authors: Esther Ngumbi and Ifeanyi Nsofor Tags: Food & Agriculture Global Headlines Health World Food Day Source Type: news

‘Salty’ Concern: Tackling High Salt Consumption in China
Veena S. Kulkarni, Associate Professor, Department of Criminology, Sociology and Geography, Arkansas State University, USA; and Raghav Gaiha, (Hon.) Professorial Research Fellow, Global Development Institute, University of Manchester, England.By Veena S. Kulkarni and Raghav GaihaNEW DELHI, India and JONESBORO, US, Oct 7 2019 (IPS) China’s almost meteoric transition from a being a low income to a middle income country within a span of four decades is often perceived as a miracle analogous to the post Second World War Japanese economic development experience. China’s GDP rose from $200 current United States dollars (US$ ...
Source: IPS Inter Press Service - Health - October 7, 2019 Category: International Medicine & Public Health Authors: Veena Kulkarni and Raghav Gaiha Tags: Asia-Pacific Development & Aid Economy & Trade Food & Agriculture Food Sustainability Globalisation Headlines Health Labour TerraViva United Nations Barilla Center for Food and Nutrition Foundation (BCFN) Source Type: news

IJERPH, Vol. 16, Pages 3665: Knowledge and Poor Understanding Factors of Stroke and Heart Attack Symptoms
Conclusions: Specialized interventions, including those based on public education, should focus on groups with less knowledge of CVD.
Source: International Journal of Environmental Research and Public Health - September 28, 2019 Category: Environmental Health Authors: Chang Hoon Han Hyeyun Kim Sujin Lee Jae Ho Chung Tags: Article Source Type: research