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Nutrition: Sodium Chloride

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Total 383 results found since Jan 2013.

Do low salt levels slow down stroke recovery? DR MARTIN SCURR answers your health questions 
DR MARTIN SCURR: Low sodium levels are also linked to conditions such as kidney failure, or excessive release of the hormone vasopressin, the so-called anti-diuretic hormone (ADH).
Source: the Mail online | Health - January 11, 2022 Category: Consumer Health News Source Type: news

Multimodal assessment of interhemispheric cortical interactions and differential behavioral relevance in upper and lower extremity motor function in chronic stroke
Abstract
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - November 1, 2021 Category: Neurology Authors: Jacqueline Palmer, Trisha Kesar, Steve Wolf, Lewis Wheaton, Mary Alice Salt ão da Silva, Michael Borich Source Type: research

Salt Substitute Cut Disease and Death Rates in Large Trial
A randomized trial recently reported in the New England Journal of Medicine focused on an important question for older adults with high blood pressure or a previous stroke: Can switching from regular salt to a 75% sodium chloride and 25% potassium chloride substitute help protect against stroke, major cardiovascular events, or death?
Source: JAMA - October 26, 2021 Category: General Medicine Source Type: research

Salt substitution reduces the rate of cardiovascular events and death
Nature Reviews Cardiology, Published online: 13 September 2021; doi:10.1038/s41569-021-00615-3In the SSaSS trial, substituting regular table salt (100% sodium chloride) with an alternative containing 25% potassium chloride reduced the rate of stroke, major cardiovascular events and all-cause death.
Source: Nature Reviews Cardiology - September 13, 2021 Category: Cardiology Authors: Gregory B. Lim Source Type: research

Sep 3 2021 This Week in Cardiology Sep 3 2021 This Week in Cardiology
EMPEROR-Preserved, the LOOP study, ablate-and-pace for AF, and salt substitute and stroke: John Mandrola, MD provides a first of two ESC reviews.theheart.org on Medscape
Source: Medscape Cardiology Headlines - September 3, 2021 Category: Cardiology Tags: Cardiology Commentary Source Type: news

Will the SSaSS Trial Silence the Salt Skeptics? Will the SSaSS Trial Silence the Salt Skeptics?
Bruce Neal gives the lowdown on the massive SSaSS trial that showed a reduction in stroke and cardiovascular events among at-risk people in rural China who used a salt substitute instead of regular table salt.theheart.org on Medscape
Source: Medscape Cardiology Headlines - September 2, 2021 Category: Cardiology Tags: Cardiology Commentary Source Type: news

Salt Substitute Reduces Stroke, CV Events, and Death Salt Substitute Reduces Stroke, CV Events, and Death
Switching from regular salt to a low-sodium salt substitute has major public health benefits, including a reduction in stroke, cardiovascular events, and death, the new landmark SSaSS shows.Medscape Medical News
Source: Medscape Cardiology Headlines - August 29, 2021 Category: Cardiology Tags: Cardiology News Source Type: news

QiShenYiQi ameliorates salt-induced hypertensive nephropathy by balancing ADRA1D and SIK1 expression in Dahl salt-sensitive rats
CONCLUSION: QSYQ not only lowered blood pressure, but also alleviated renal damage via reducing the expression of ADRA1D and increasing the expression of SIK1 in the kidney of Dahl salt-sensitive hypertensive rats.PMID:34328102 | DOI:10.1016/j.biopha.2021.111941
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 30, 2021 Category: Drugs & Pharmacology Authors: Hongxia Du Guangxu Xiao Zhifeng Xue Zhixiong Li Shuang He Xiaoli Du Zhengchan Zhou Linghua Cao Yule Wang Jian Yang Xiaoying Wang Yan Zhu Source Type: research

A Single-Center Clinical Study to Evaluate Shenxiong Glucose Injection Combined with Edaravone in the Treatment of Acute Large-Area Cerebral Infarction
CONCLUSIONS: In addition to the routine basic treatment of acute large-area cerebral infarction, the addition of Shenxiong glucose injection combined with edaravone injection can improve platelet aggregation and reduce inflammation by affecting P-selectin, D-dimer, and FIB. This treatment approach promotes the recovery of nerve defect function without obvious adverse reactions in patients with acute large-area cerebral infarction.PMID:34307676 | PMC:PMC8263277 | DOI:10.1155/2021/9935752
Source: Biomed Res - July 26, 2021 Category: Research Authors: Zongqin Li Xiaoxia Rong Jun Luo Tao Zeng Pan Huang Xuejie Xu Source Type: research

Protocol for the economic evaluation of the China Salt Substitute and Stroke Study (SSaSS)
This study protocol describes the planned within-trial economic evaluation of a low-sodium salt substitute intervention designed to reduce the risk of stroke in China. Methods and analyses The economic evaluation will be conducted alongside the Salt Substitute and Stroke Study: a 5-year large scale, cluster randomised controlled trial. The outcomes of interest are quality of life measured using the EuroQol-5-Dimensions and major adverse cardiovascular events. Costs will be estimated from a healthcare system perspective and will be sought from the routinely collected data available within the New Rural Cooperative Medical ...
Source: BMJ Open - July 20, 2021 Category: General Medicine Authors: Li, K.-C., Tian, M., Neal, B., Huang, L., Yu, J., Liu, Y., Yin, X., Zhang, X., Wu, Y., Li, N., Elliott, P., Yan, L., Labarthe, D., Hao, Z., Shi, J., Feng, X., Zhang, J., Zhang, Y., Zhang, R., Zhou, B., Li, Z., Sun, J., Zhao, Y., Yu, Y., Si, L., Lung, T. Tags: Open access, Health economics Source Type: research

Plasma Kallikrein Contributes to Intracerebral Hemorrhage and Hypertension in Stroke-Prone Spontaneously Hypertensive Rats
This report investigates the role of PKa on hemorrhage and hypertension in stroke-prone spontaneously hypertensive rats (SHRSP). SHRSP were fed with a high salt-containing stroke-prone diet to increase blood pressure and induce intracerebral hemorrhage. The roles of PKa on blood pressure, hemorrhage, and survival in SHRSP were examined in rats receiving a PKa inhibitor or plasma prekallikrein antisense oligonucleotide (PK ASO) compared with rats receiving control ASO. Effects on PKa on the proteolytic cleavage of atrial natriuretic peptide (ANP) were analyzed by tandem mass spectrometry. We show that SHRSP on high-salt die...
Source: Cell Research - July 9, 2021 Category: Cytology Authors: Jian Guan Allen C Clermont Loc-Duyen Pham Tuna Ustunkaya Alexey S Revenko A Robert MacLeod Edward P Feener Fabr ício Simão Source Type: research

Thromboxane A < sub > 2 < /sub > receptor antagonist (ONO-8809) attenuates renal disorders caused by salt overload in stroke-prone spontaneously hypertensive rats
In this study, we focused on evaluating the histological and gene expression effects in the kidneys of stroke-prone spontaneously hypertensive rats (SHRSP) with a high salt intake and the thromboxane A2 / prostaglandin H2 receptor (TPR) blocker ONO-8809. Six-week-old SHRSPs aged 6 weeks, were divided into three groups and were fed normal chow containing 0.4% NaCl, 2.0%NaCl, or 2.0%NaCl +ONO-8809 (0.6 mg/kg p.o. daily). Histological analyses with immunohistochemistry and a gene expression assay with a DNA kidney microarray were performed after eight weeks. The following changes were observed in SHRSPs with the high salt int...
Source: Clinical and Experimental Pharmacology and Physiology - June 21, 2021 Category: Drugs & Pharmacology Authors: Yusuke Nagatani Toshihide Higashino Kosho Kinoshita Hideaki Higashino Source Type: research