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Nutrition: Sodium Chloride

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Total 383 results found since Jan 2013.

Med Nonadherence in Key Trials; Atrial Cardiopathy and Dementia; Diabetes on ECG?
(MedPage Today) -- Salt substitutes were associated with a reduced risk of heart attack, stroke, and death, according to a meta-analysis. (Heart) The American College of Chest Physicians updates its guidelines on the perioperative management of...
Source: MedPage Today Cardiovascular - August 17, 2022 Category: Cardiology Source Type: news

More Evidence Salt Substitutes Lower Risk of CVD and Death More Evidence Salt Substitutes Lower Risk of CVD and Death
The blood pressure –lowering effects of dietary salt substitutes have a clear protective effect on hard clinical outcomes, leading to a reduction in heart attack, stroke, and death, a meta-analysis shows.Medscape Medical News
Source: Medscape Cardiology Headlines - August 10, 2022 Category: Cardiology Tags: Cardiology News Source Type: news

Replacing salt with low-sodium salt substitutes (LSSS) for cardiovascular health in adults, children and pregnant women
CONCLUSIONS: When compared to regular salt, LSSS probably reduce blood pressure, non-fatal cardiovascular events and cardiovascular mortality slightly in adults. However, LSSS also probably increase blood potassium slightly in adults. These small effects may be important when LSSS interventions are implemented at the population level. Evidence is limited for adults without elevated blood pressure, and there is a lack of evidence in pregnant women and people in whom an increased potassium intake is known to be potentially harmful, limiting conclusions on the safety of LSSS in the general population. We also cannot draw firm...
Source: Cochrane Database of Systematic Reviews - August 9, 2022 Category: General Medicine Authors: Amanda Brand Marianne E Visser Anel Schoonees Celeste E Naude Source Type: research

8/10 --A Switch to Salt Substitute Could Slash Your Heart Risks
WEDNESDAY, Aug. 10, 2022 -- Swapping salt out for the salt substitute potassium chloride lowers blood pressure, and thereby the risk of heart attack, stroke and cardiovascular disease, a new analysis finds. " It ' s in processed and prepared foods...
Source: Drugs.com - Daily MedNews - August 8, 2022 Category: General Medicine Source Type: news

Modulation of blood pressure regulatory genes in the Agtrap ‐Plod1 locus associated with a deletion in Clcn6
In this study, we tested whether loss ofClcn6 would be protective against high salt-induced mortality. While we observed no significant differences in longevity or neuronal cell death between the SS-Clcn6 knock-out and SS-WT groups, we found that a mutation inClcn6 could be associated with changes to mRNA expression of nearbyMthfr,Nppa, andNppb genes, thereby complicating the genetic phenotype of our knockout animal. AbstractThe AGTRAP-PLOD1 locus is a conserved gene cluster containing several blood pressure regulatory genes, includingCLCN6,MTHFR,NPPA, andNPPB. Previous work revealed that knockout ofClcn6 on the Dahl Salt-...
Source: Physiological Reports - August 5, 2022 Category: Physiology Authors: Christine A. Klemens, Lashodya V. Dissanayake, Vladislav Levchenko, Adrian Zietara, Oleg Palygin, Alexander Staruschenko Tags: ORIGINAL ARTICLE Source Type: research

Low dietary sodium potentially mediates COVID-19 prevention associated with whole food plant-based diets
This article presents evidence that low dietary sodium potentially mediates the association of plant-based diets with COVID-19 prevention. Processed meats and poultry injected with sodium chloride contribute considerable amounts of dietary sodium in the Western diet, and the avoidance or reduction of these and other processed foods in whole food plant-based diets could help lower overall dietary sodium intake. Moreover, high amounts of potassium in plant-based diets increase urinary sodium excretion, and preagricultural diets high in plant-based foods were estimated to contain much lower ratios of dietary sodium to potassi...
Source: The British Journal of Nutrition - August 1, 2022 Category: Nutrition Authors: Ronald B Brown Source Type: research

Grading of Japanese Diet Intakes by 24-Hour Urine Analysis of Taurine and Soy Isoflavones in Relation to Cardiovascular Risks
In conclusion, the higher the J score, which corresponds to Japanese dietary habits, the lower the BMI and cholesterol levels, as well as mortality rate from coronary heart disease, but the higher the average life expectancy among the Japanese. However, these higher J scorings were associated with high-salt intake and high Na/K ratios; therefore, they contributed to high blood pressure and high mortality rate caused by stroke in Japan. These results indicate that low-salt intake should be recommended to the Japanese who are consuming seafood and soy regularly in order to maintain lower blood pressure and to extend healthy ...
Source: Advances in Experimental Medicine and Biology - July 26, 2022 Category: Research Authors: Mari Mori Miki Sagara Hideki Mori Yukio Yamori Source Type: research

The role of microglial/macrophagic salt-inducible kinase 3 on normal and excessive phagocytosis after transient focal cerebral ischemia
This study is the first to show a role of SIK3 in Mi/MΦ phagocytosis in CNS diseases, and reveals that promoting Mi/MΦ anti-inflammatory heterogenization inhibits "excessive phagocytosis" of live cells and facilitates "normal phagocytosis" of apoptotic cells. Therefore, inhibition of SIK3 in Mi/MΦ may be a potential therapeutic target in stroke and other CNS diseases with accompanying white matter destruction. In the acute stage of tFCI, Mi/MΦ polarized into different phenotypes. The pro-inflammatory Mi/MΦ phenotype performed an excessive phagocytotic function. In contrast, the anti-inflammatory Mi/MΦ phenotype perfo...
Source: Cellular and Molecular Life Sciences : CMLS - July 21, 2022 Category: Cytology Authors: Ke Wang Chenran Wang Di Chen Yichen Huang Jiaying Li Pengju Wei Ziyu Shi Yue Zhang Yanqin Gao Source Type: research