Together, We've Got This: The US Surgeon General's Call-to-Action on Hypertension Control
Am J Hypertens. 2021 Jul 27:hpaa172. doi: 10.1093/ajh/hpaa172. Online ahead of print.NO ABSTRACTPMID:34313678 | DOI:10.1093/ajh/hpaa172 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 27, 2021 Category: Cardiology Authors: Paul Muntner Shakia T Hardy Source Type: research

Together, We've Got This: The US Surgeon General's Call-to-Action on Hypertension Control
Am J Hypertens. 2021 Jul 27:hpaa172. doi: 10.1093/ajh/hpaa172. Online ahead of print.NO ABSTRACTPMID:34313678 | DOI:10.1093/ajh/hpaa172 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 27, 2021 Category: Cardiology Authors: Paul Muntner Shakia T Hardy Source Type: research

Commentary on "Lifestyle Interventions Reduce the Need for Guideline-Directed Antihypertensive Medication"
Am J Hypertens. 2021 Jul 23:hpab117. doi: 10.1093/ajh/hpab117. Online ahead of print.NO ABSTRACTPMID:34297050 | DOI:10.1093/ajh/hpab117 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 23, 2021 Category: Cardiology Authors: Eirini D Basdeki Kalliopi Karatzi Athanase D Protogerou Source Type: research

Commentary on "Lifestyle Interventions Reduce the Need for Guideline-Directed Antihypertensive Medication"
Am J Hypertens. 2021 Jul 23:hpab117. doi: 10.1093/ajh/hpab117. Online ahead of print.NO ABSTRACTPMID:34297050 | DOI:10.1093/ajh/hpab117 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 23, 2021 Category: Cardiology Authors: Eirini D Basdeki Kalliopi Karatzi Athanase D Protogerou Source Type: research

Commentary on "Lifestyle Interventions Reduce the Need for Guideline-Directed Antihypertensive Medication"
Am J Hypertens. 2021 Jul 23:hpab117. doi: 10.1093/ajh/hpab117. Online ahead of print.NO ABSTRACTPMID:34297050 | DOI:10.1093/ajh/hpab117 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 23, 2021 Category: Cardiology Authors: Eirini D Basdeki Kalliopi Karatzi Athanase D Protogerou Source Type: research

24-Hour Blood Pressure Variability is Associated with Lower Cognitive Performance in Young Women with a Recent History of Preeclampsia
The objectives of this study were to 1) test whether cognitive performance is lower in young women with hxPE and 2) determine whether aortic stiffness and BPV are associated with cognitive performance independent of 24-hour average BP.METHODS: Women with hxPE (N=23) and healthy pregnancy controls (N=38) were enrolled 1-3 years postpartum. Cognitive performance was assessed in domains of memory, processing speed and executive function. 24-hour ambulatory BP monitoring and carotid-femoral pulse wave velocity (cfPWV) were used to measure BPV and aortic stiffness, respectively.RESULTS: Women with hxPE had slower processing spe...
Source: American Journal of Hypertension - July 19, 2021 Category: Cardiology Authors: Virginia R Nuckols Amy K Stroud Jared F Hueser Debra S Brandt Lyndsey E DuBose Donna A Santillan Mark K Santillan Gary L Pierce Source Type: research

Awareness, Knowledge, and Attitudes Toward Screening and Treatment of Masked Hypertension in Primary Care
CONCLUSIONS: Limited PCP knowledge about MHT, concerns about the accuracy and accessibility of screening tests, overloaded PCPs, and insufficient evidence were major barriers to screening and treatment for MHT. Prior to broad uptake by PCPs, randomized trials demonstrating the net benefits of MHT screening and treatment may be needed, along with increased dissemination of knowledge about MHT and improved access to ABPM.PMID:34279025 | DOI:10.1093/ajh/hpab115 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 19, 2021 Category: Cardiology Authors: Rebekah Boyd Eileen Carter Nathalie Moise Carmela Alcantara Thais Valadares Edmund Anstey Ian M Kronish Source Type: research

24-Hour Blood Pressure Variability is Associated with Lower Cognitive Performance in Young Women with a Recent History of Preeclampsia
The objectives of this study were to 1) test whether cognitive performance is lower in young women with hxPE and 2) determine whether aortic stiffness and BPV are associated with cognitive performance independent of 24-hour average BP.METHODS: Women with hxPE (N=23) and healthy pregnancy controls (N=38) were enrolled 1-3 years postpartum. Cognitive performance was assessed in domains of memory, processing speed and executive function. 24-hour ambulatory BP monitoring and carotid-femoral pulse wave velocity (cfPWV) were used to measure BPV and aortic stiffness, respectively.RESULTS: Women with hxPE had slower processing spe...
Source: American Journal of Hypertension - July 19, 2021 Category: Cardiology Authors: Virginia R Nuckols Amy K Stroud Jared F Hueser Debra S Brandt Lyndsey E DuBose Donna A Santillan Mark K Santillan Gary L Pierce Source Type: research

Awareness, Knowledge, and Attitudes Toward Screening and Treatment of Masked Hypertension in Primary Care
CONCLUSIONS: Limited PCP knowledge about MHT, concerns about the accuracy and accessibility of screening tests, overloaded PCPs, and insufficient evidence were major barriers to screening and treatment for MHT. Prior to broad uptake by PCPs, randomized trials demonstrating the net benefits of MHT screening and treatment may be needed, along with increased dissemination of knowledge about MHT and improved access to ABPM.PMID:34279025 | DOI:10.1093/ajh/hpab115 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 19, 2021 Category: Cardiology Authors: Rebekah Boyd Eileen Carter Nathalie Moise Carmela Alcantara Thais Valadares Edmund Anstey Ian M Kronish Source Type: research

24-Hour Blood Pressure Variability is Associated with Lower Cognitive Performance in Young Women with a Recent History of Preeclampsia
The objectives of this study were to 1) test whether cognitive performance is lower in young women with hxPE and 2) determine whether aortic stiffness and BPV are associated with cognitive performance independent of 24-hour average BP.METHODS: Women with hxPE (N=23) and healthy pregnancy controls (N=38) were enrolled 1-3 years postpartum. Cognitive performance was assessed in domains of memory, processing speed and executive function. 24-hour ambulatory BP monitoring and carotid-femoral pulse wave velocity (cfPWV) were used to measure BPV and aortic stiffness, respectively.RESULTS: Women with hxPE had slower processing spe...
Source: American Journal of Hypertension - July 19, 2021 Category: Cardiology Authors: Virginia R Nuckols Amy K Stroud Jared F Hueser Debra S Brandt Lyndsey E DuBose Donna A Santillan Mark K Santillan Gary L Pierce Source Type: research

Awareness, Knowledge, and Attitudes Toward Screening and Treatment of Masked Hypertension in Primary Care
CONCLUSIONS: Limited PCP knowledge about MHT, concerns about the accuracy and accessibility of screening tests, overloaded PCPs, and insufficient evidence were major barriers to screening and treatment for MHT. Prior to broad uptake by PCPs, randomized trials demonstrating the net benefits of MHT screening and treatment may be needed, along with increased dissemination of knowledge about MHT and improved access to ABPM.PMID:34279025 | DOI:10.1093/ajh/hpab115 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 19, 2021 Category: Cardiology Authors: Rebekah Boyd Eileen Carter Nathalie Moise Carmela Alcantara Thais Valadares Edmund Anstey Ian M Kronish Source Type: research

24-Hour Blood Pressure Variability is Associated with Lower Cognitive Performance in Young Women with a Recent History of Preeclampsia
The objectives of this study were to 1) test whether cognitive performance is lower in young women with hxPE and 2) determine whether aortic stiffness and BPV are associated with cognitive performance independent of 24-hour average BP.METHODS: Women with hxPE (N=23) and healthy pregnancy controls (N=38) were enrolled 1-3 years postpartum. Cognitive performance was assessed in domains of memory, processing speed and executive function. 24-hour ambulatory BP monitoring and carotid-femoral pulse wave velocity (cfPWV) were used to measure BPV and aortic stiffness, respectively.RESULTS: Women with hxPE had slower processing spe...
Source: American Journal of Hypertension - July 19, 2021 Category: Cardiology Authors: Virginia R Nuckols Amy K Stroud Jared F Hueser Debra S Brandt Lyndsey E DuBose Donna A Santillan Mark K Santillan Gary L Pierce Source Type: research

Awareness, Knowledge, and Attitudes Toward Screening and Treatment of Masked Hypertension in Primary Care
CONCLUSIONS: Limited PCP knowledge about MHT, concerns about the accuracy and accessibility of screening tests, overloaded PCPs, and insufficient evidence were major barriers to screening and treatment for MHT. Prior to broad uptake by PCPs, randomized trials demonstrating the net benefits of MHT screening and treatment may be needed, along with increased dissemination of knowledge about MHT and improved access to ABPM.PMID:34279025 | DOI:10.1093/ajh/hpab115 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 19, 2021 Category: Cardiology Authors: Rebekah Boyd Eileen Carter Nathalie Moise Carmela Alcantara Thais Valadares Edmund Anstey Ian M Kronish Source Type: research

African Ancestry vs Creatine Kinase to Predict Hypertension Control: Time for a Change?
CONCLUSION: In contrast to African ancestry, CK might identify hypertensive patients at risk for therapy failure across different ancestry groups. Larger, prospective studies should establish whether resting plasma CK is clinically useful as an impartial method to help predict antihypertensive therapy failure.PMID:34272843 | DOI:10.1093/ajh/hpab114 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 17, 2021 Category: Cardiology Authors: L M Brewster I Van Valkengoed G A van Montfrans Source Type: research

Stress and Depression are Associated with Life's Simple 7 Among African Americans with Hypertension: Findings from the Jackson Heart Study
CONCLUSIONS: The combination of high stress and high depressive symptoms was associated with poorer LS7 metrics in hypertensive African Americans. Psychosocial interventions may increase the likelihood of engaging in behaviors that promote optimal cardiovascular health.PMID:34272853 | DOI:10.1093/ajh/hpab116 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 17, 2021 Category: Cardiology Authors: Aisha T Langford Mark Butler John N Booth Iii Peng Jin Adam P Bress Rikki M Tanner Jolaade Kalinowski Judite Blanc Azizi Seixas Daichi Shimbo Mario Sims Gbenga Ogedegbe Tanya M Spruill Source Type: research

African Ancestry vs Creatine Kinase to Predict Hypertension Control: Time for a Change?
CONCLUSION: In contrast to African ancestry, CK might identify hypertensive patients at risk for therapy failure across different ancestry groups. Larger, prospective studies should establish whether resting plasma CK is clinically useful as an impartial method to help predict antihypertensive therapy failure.PMID:34272843 | DOI:10.1093/ajh/hpab114 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 17, 2021 Category: Cardiology Authors: L M Brewster I Van Valkengoed G A van Montfrans Source Type: research

Stress and Depression are Associated with Life's Simple 7 Among African Americans with Hypertension: Findings from the Jackson Heart Study
CONCLUSIONS: The combination of high stress and high depressive symptoms was associated with poorer LS7 metrics in hypertensive African Americans. Psychosocial interventions may increase the likelihood of engaging in behaviors that promote optimal cardiovascular health.PMID:34272853 | DOI:10.1093/ajh/hpab116 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 17, 2021 Category: Cardiology Authors: Aisha T Langford Mark Butler John N Booth Iii Peng Jin Adam P Bress Rikki M Tanner Jolaade Kalinowski Judite Blanc Azizi Seixas Daichi Shimbo Mario Sims Gbenga Ogedegbe Tanya M Spruill Source Type: research

African Ancestry vs Creatine Kinase to Predict Hypertension Control: Time for a Change?
CONCLUSION: In contrast to African ancestry, CK might identify hypertensive patients at risk for therapy failure across different ancestry groups. Larger, prospective studies should establish whether resting plasma CK is clinically useful as an impartial method to help predict antihypertensive therapy failure.PMID:34272843 | DOI:10.1093/ajh/hpab114 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 17, 2021 Category: Cardiology Authors: L M Brewster I Van Valkengoed G A van Montfrans Source Type: research

Stress and Depression are Associated with Life's Simple 7 Among African Americans with Hypertension: Findings from the Jackson Heart Study
CONCLUSIONS: The combination of high stress and high depressive symptoms was associated with poorer LS7 metrics in hypertensive African Americans. Psychosocial interventions may increase the likelihood of engaging in behaviors that promote optimal cardiovascular health.PMID:34272853 | DOI:10.1093/ajh/hpab116 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 17, 2021 Category: Cardiology Authors: Aisha T Langford Mark Butler John N Booth Iii Peng Jin Adam P Bress Rikki M Tanner Jolaade Kalinowski Judite Blanc Azizi Seixas Daichi Shimbo Mario Sims Gbenga Ogedegbe Tanya M Spruill Source Type: research

Restating well-known determinants for blood pressure: Do classification trees help?
Am J Hypertens. 2021 Jul 16:hpab113. doi: 10.1093/ajh/hpab113. Online ahead of print.NO ABSTRACTPMID:34270673 | DOI:10.1093/ajh/hpab113 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 16, 2021 Category: Cardiology Authors: Yuri V Sebasti ão Chighaf Bakour Skai W Schwartz Source Type: research

Lifestyle behaviors among adults recommended for ambulatory blood pressure monitoring according to the 2017 ACC/AHA blood pressure guideline
CONCLUSIONS: Few participants who met office BP criteria for the screening of WCH or MHT had ideal lifestyle factors.PMID:34270687 | DOI:10.1093/ajh/hpab110 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 16, 2021 Category: Cardiology Authors: Laura P Cohen Demetria Hubbard Calvin L Colvin Byron C Jaeger Bharat Poudel Marwah Abdalla Aisha Langford Shakia T Hardy Mario Sims Cora E Lewis Paul Muntner Daichi Shimbo Source Type: research

Renin Angiotensin blockers and cardiac protection. From basis to clinical trials
Am J Hypertens. 2021 Jul 15:hpab108. doi: 10.1093/ajh/hpab108. Online ahead of print.ABSTRACTDespite a similar beneficial effect on blood-pressure lowering observed with ACEIs and ARBs, several clinical trials and meta-analyses have reported higher cardiovascular mortality and lower protection against myocardial infarction with ARBs when compared to ACEIs. The European guidelines for the management of coronary syndromes and European guidelines on diabetes recommend using ARBs in patients who are intolerant to ACEIs. We reviewed the main pharmacological differences between ACEIs and ARBs which could provide insights into th...
Source: American Journal of Hypertension - July 15, 2021 Category: Cardiology Authors: Bernard I L évy Jean Jacques Mourad Source Type: research

Effects of Renin-Angiotensin-Aldosterone Inhibitors on Early Outcomes of Hypertensive COVID-19 Patients: A Randomized Triple-Blind Clinical Trial
CONCLUSIONS: This randomized triple-blind multi-centric clinical trial did not show any deleterious effects of ACEi/ARB medications in hypertensive COVID-19 patients.PMID:34265044 | DOI:10.1093/ajh/hpab111 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 15, 2021 Category: Cardiology Authors: Farhad Najmeddin Maedeh Solhjoo Haleh Ashraf Mohammadreza Salehi Fatemeh Rasooli Morteza Ghoghaei Abbas Soleimani Maryam Bahreini Source Type: research

Renin Angiotensin blockers and cardiac protection. From basis to clinical trials
Am J Hypertens. 2021 Jul 15:hpab108. doi: 10.1093/ajh/hpab108. Online ahead of print.ABSTRACTDespite a similar beneficial effect on blood-pressure lowering observed with ACEIs and ARBs, several clinical trials and meta-analyses have reported higher cardiovascular mortality and lower protection against myocardial infarction with ARBs when compared to ACEIs. The European guidelines for the management of coronary syndromes and European guidelines on diabetes recommend using ARBs in patients who are intolerant to ACEIs. We reviewed the main pharmacological differences between ACEIs and ARBs which could provide insights into th...
Source: American Journal of Hypertension - July 15, 2021 Category: Cardiology Authors: Bernard I L évy Jean Jacques Mourad Source Type: research

Effects of Renin-Angiotensin-Aldosterone Inhibitors on Early Outcomes of Hypertensive COVID-19 Patients: A Randomized Triple-Blind Clinical Trial
CONCLUSIONS: This randomized triple-blind multi-centric clinical trial did not show any deleterious effects of ACEi/ARB medications in hypertensive COVID-19 patients.PMID:34265044 | DOI:10.1093/ajh/hpab111 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 15, 2021 Category: Cardiology Authors: Farhad Najmeddin Maedeh Solhjoo Haleh Ashraf Mohammadreza Salehi Fatemeh Rasooli Morteza Ghoghaei Abbas Soleimani Maryam Bahreini Source Type: research

Midlife Blood Pressure Variability and Risk of All-Cause Mortality and Cardiovascular Events During Extended Follow-Up
CONCLUSION: Long-term BPV during midlife is an independent predictor of later life mortality but not cardiovascular events.PMID:34240111 | DOI:10.1093/ajh/hpab106 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 9, 2021 Category: Cardiology Authors: Adam de Havenon Alen Delic Shadi Yaghi Ka-Ho Wong Jennifer J Majersik Eric Stulberg David Tirschwell Mohammad Anadani Source Type: research

Assessing the relationship between history of arrest and self-reported cardiovascular conditions
CONCLUSIONS: We did not find evidence that history of arrest, a lower-level criminal legal system exposure, is associated with self-reported hypertension or heart conditions.PMID:34240119 | DOI:10.1093/ajh/hpab107 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 9, 2021 Category: Cardiology Authors: Meghan Bellerose Diandian Yilin Tawandra L Rowell-Cunsolo Source Type: research

Midlife Blood Pressure Variability and Risk of All-Cause Mortality and Cardiovascular Events During Extended Follow-Up
CONCLUSION: Long-term BPV during midlife is an independent predictor of later life mortality but not cardiovascular events.PMID:34240111 | DOI:10.1093/ajh/hpab106 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 9, 2021 Category: Cardiology Authors: Adam de Havenon Alen Delic Shadi Yaghi Ka-Ho Wong Jennifer J Majersik Eric Stulberg David Tirschwell Mohammad Anadani Source Type: research

Assessing the relationship between history of arrest and self-reported cardiovascular conditions
CONCLUSIONS: We did not find evidence that history of arrest, a lower-level criminal legal system exposure, is associated with self-reported hypertension or heart conditions.PMID:34240119 | DOI:10.1093/ajh/hpab107 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 9, 2021 Category: Cardiology Authors: Meghan Bellerose Diandian Yilin Tawandra L Rowell-Cunsolo Source Type: research

Midlife Blood Pressure Variability and Risk of All-Cause Mortality and Cardiovascular Events During Extended Follow-Up
CONCLUSION: Long-term BPV during midlife is an independent predictor of later life mortality but not cardiovascular events.PMID:34240111 | DOI:10.1093/ajh/hpab106 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 9, 2021 Category: Cardiology Authors: Adam de Havenon Alen Delic Shadi Yaghi Ka-Ho Wong Jennifer J Majersik Eric Stulberg David Tirschwell Mohammad Anadani Source Type: research

Assessing the relationship between history of arrest and self-reported cardiovascular conditions
CONCLUSIONS: We did not find evidence that history of arrest, a lower-level criminal legal system exposure, is associated with self-reported hypertension or heart conditions.PMID:34240119 | DOI:10.1093/ajh/hpab107 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 9, 2021 Category: Cardiology Authors: Meghan Bellerose Diandian Yilin Tawandra L Rowell-Cunsolo Source Type: research

Midlife Blood Pressure Variability and Risk of All-Cause Mortality and Cardiovascular Events During Extended Follow-Up
CONCLUSION: Long-term BPV during midlife is an independent predictor of later life mortality but not cardiovascular events.PMID:34240111 | DOI:10.1093/ajh/hpab106 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 9, 2021 Category: Cardiology Authors: Adam de Havenon Alen Delic Shadi Yaghi Ka-Ho Wong Jennifer J Majersik Eric Stulberg David Tirschwell Mohammad Anadani Source Type: research

Assessing the relationship between history of arrest and self-reported cardiovascular conditions
CONCLUSIONS: We did not find evidence that history of arrest, a lower-level criminal legal system exposure, is associated with self-reported hypertension or heart conditions.PMID:34240119 | DOI:10.1093/ajh/hpab107 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 9, 2021 Category: Cardiology Authors: Meghan Bellerose Diandian Yilin Tawandra L Rowell-Cunsolo Source Type: research

Midlife Blood Pressure Variability and Risk of All-Cause Mortality and Cardiovascular Events During Extended Follow-Up
CONCLUSION: Long-term BPV during midlife is an independent predictor of later life mortality but not cardiovascular events.PMID:34240111 | DOI:10.1093/ajh/hpab106 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 9, 2021 Category: Cardiology Authors: Adam de Havenon Alen Delic Shadi Yaghi Ka-Ho Wong Jennifer J Majersik Eric Stulberg David Tirschwell Mohammad Anadani Source Type: research

Assessing the relationship between history of arrest and self-reported cardiovascular conditions
CONCLUSIONS: We did not find evidence that history of arrest, a lower-level criminal legal system exposure, is associated with self-reported hypertension or heart conditions.PMID:34240119 | DOI:10.1093/ajh/hpab107 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - July 9, 2021 Category: Cardiology Authors: Meghan Bellerose Diandian Yilin Tawandra L Rowell-Cunsolo Source Type: research

Plasma ceramides and cardiovascular events in hypertensive patients at high cardiovascular risk
Am J Hypertens. 2021 Jul 7:hpab105. doi: 10.1093/ajh/hpab105. Online ahead of print.ABSTRACTBACKGROUND: Plasma ceramides (Cer) have been used to evaluate risk of cardiovascular events in patients with coronary heart disease. We investigated the performance of ceramides and ceramide score (CERT) in hypertensive patients at high cardiovascular risk.METHODS: Seven ceramides were analyzed using ultra-performance liquid chromatography-tandem mass spectrometry in 920 essential hypertension patients at high cardiovascular risk, who visited Beijing Anzhen Hospital from September 2016 to September 2018 (median age: 49 years, 562 ma...
Source: American Journal of Hypertension - July 7, 2021 Category: Cardiology Authors: Wenjie Yin Fengjuan Li Xin Tan Huimin Wang Wenxi Jiang Xue Wang Sijin Li Yanbo Zhang Qinghua Han Yuan Wang Jie Du Source Type: research

Plasma ceramides and cardiovascular events in hypertensive patients at high cardiovascular risk
Am J Hypertens. 2021 Jul 7:hpab105. doi: 10.1093/ajh/hpab105. Online ahead of print.ABSTRACTBACKGROUND: Plasma ceramides (Cer) have been used to evaluate risk of cardiovascular events in patients with coronary heart disease. We investigated the performance of ceramides and ceramide score (CERT) in hypertensive patients at high cardiovascular risk.METHODS: Seven ceramides were analyzed using ultra-performance liquid chromatography-tandem mass spectrometry in 920 essential hypertension patients at high cardiovascular risk, who visited Beijing Anzhen Hospital from September 2016 to September 2018 (median age: 49 years, 562 ma...
Source: American Journal of Hypertension - July 7, 2021 Category: Cardiology Authors: Wenjie Yin Fengjuan Li Xin Tan Huimin Wang Wenxi Jiang Xue Wang Sijin Li Yanbo Zhang Qinghua Han Yuan Wang Jie Du Source Type: research

Plasma ceramides and cardiovascular events in hypertensive patients at high cardiovascular risk
Am J Hypertens. 2021 Jul 7:hpab105. doi: 10.1093/ajh/hpab105. Online ahead of print.ABSTRACTBACKGROUND: Plasma ceramides (Cer) have been used to evaluate risk of cardiovascular events in patients with coronary heart disease. We investigated the performance of ceramides and ceramide score (CERT) in hypertensive patients at high cardiovascular risk.METHODS: Seven ceramides were analyzed using ultra-performance liquid chromatography-tandem mass spectrometry in 920 essential hypertension patients at high cardiovascular risk, who visited Beijing Anzhen Hospital from September 2016 to September 2018 (median age: 49 years, 562 ma...
Source: American Journal of Hypertension - July 7, 2021 Category: Cardiology Authors: Wenjie Yin Fengjuan Li Xin Tan Huimin Wang Wenxi Jiang Xue Wang Sijin Li Yanbo Zhang Qinghua Han Yuan Wang Jie Du Source Type: research

Endothelin-1 and Parameters of Systolic Blood Pressure in Hemodialysis
CONCLUSIONS: Higher baseline ET-1 levels are independently associated with higher SBP and higher odds of intra-dialytic hypertension. These results highlight a potential role for ET-1 in BP control in HD patients and raise the possibility of ET-1 antagonism as a therapeutic target.PMID:34192305 | DOI:10.1093/ajh/hpab104 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - June 30, 2021 Category: Cardiology Authors: Anika T Singh Suraj Sarvode Mothi Ping Li Venkata Sabbisetti Sushrut S Waikar Finnian R Mc Causland Source Type: research

Endothelin-1 and Parameters of Systolic Blood Pressure in Hemodialysis
CONCLUSIONS: Higher baseline ET-1 levels are independently associated with higher SBP and higher odds of intra-dialytic hypertension. These results highlight a potential role for ET-1 in BP control in HD patients and raise the possibility of ET-1 antagonism as a therapeutic target.PMID:34192305 | DOI:10.1093/ajh/hpab104 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - June 30, 2021 Category: Cardiology Authors: Anika T Singh Suraj Sarvode Mothi Ping Li Venkata Sabbisetti Sushrut S Waikar Finnian R Mc Causland Source Type: research

Endothelin-1 and Parameters of Systolic Blood Pressure in Hemodialysis
CONCLUSIONS: Higher baseline ET-1 levels are independently associated with higher SBP and higher odds of intra-dialytic hypertension. These results highlight a potential role for ET-1 in BP control in HD patients and raise the possibility of ET-1 antagonism as a therapeutic target.PMID:34192305 | DOI:10.1093/ajh/hpab104 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - June 30, 2021 Category: Cardiology Authors: Anika T Singh Suraj Sarvode Mothi Ping Li Venkata Sabbisetti Sushrut S Waikar Finnian R Mc Causland Source Type: research

Endothelin-1 and Parameters of Systolic Blood Pressure in Hemodialysis
CONCLUSIONS: Higher baseline ET-1 levels are independently associated with higher SBP and higher odds of intra-dialytic hypertension. These results highlight a potential role for ET-1 in BP control in HD patients and raise the possibility of ET-1 antagonism as a therapeutic target.PMID:34192305 | DOI:10.1093/ajh/hpab104 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - June 30, 2021 Category: Cardiology Authors: Anika T Singh Suraj Sarvode Mothi Ping Li Venkata Sabbisetti Sushrut S Waikar Finnian R Mc Causland Source Type: research

Endothelin-1 and Parameters of Systolic Blood Pressure in Hemodialysis
CONCLUSIONS: Higher baseline ET-1 levels are independently associated with higher SBP and higher odds of intra-dialytic hypertension. These results highlight a potential role for ET-1 in BP control in HD patients and raise the possibility of ET-1 antagonism as a therapeutic target.PMID:34192305 | DOI:10.1093/ajh/hpab104 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - June 30, 2021 Category: Cardiology Authors: Anika T Singh Suraj Sarvode Mothi Ping Li Venkata Sabbisetti Sushrut S Waikar Finnian R Mc Causland Source Type: research

Endothelin-1 and Parameters of Systolic Blood Pressure in Hemodialysis
CONCLUSIONS: Higher baseline ET-1 levels are independently associated with higher SBP and higher odds of intra-dialytic hypertension. These results highlight a potential role for ET-1 in BP control in HD patients and raise the possibility of ET-1 antagonism as a therapeutic target.PMID:34192305 | DOI:10.1093/ajh/hpab104 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - June 30, 2021 Category: Cardiology Authors: Anika T Singh Suraj Sarvode Mothi Ping Li Venkata Sabbisetti Sushrut S Waikar Finnian R Mc Causland Source Type: research

Hypertension And The Kidney: Reduced Kidney Mass Is Bad For Both Normotensive And Hypertensive Rats
CONCLUSIONS: The long-term severity of kidney injury correlated with higher blood pressure. . Reduction of the kidney mass increases SCr, hematuria, proteinuria and blood pressure in both normotensive and hypertensive rats. Histological assessment provides better information about underlying chronic kidney injury than actual changes in SCr and urinalysis.PMID:34181718 | DOI:10.1093/ajh/hpab103 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - June 28, 2021 Category: Cardiology Authors: Kyle Ware Vedat Yildiz Min Xiao Ajay Medipally Jessica Hemminger Rachel Scarl Anjali A Satoskar Lee Hebert Iouri Ivanov Laura Biederman Sergey V Brodsky Source Type: research

Hypertension And The Kidney: Reduced Kidney Mass Is Bad For Both Normotensive And Hypertensive Rats
CONCLUSIONS: The long-term severity of kidney injury correlated with higher blood pressure. . Reduction of the kidney mass increases SCr, hematuria, proteinuria and blood pressure in both normotensive and hypertensive rats. Histological assessment provides better information about underlying chronic kidney injury than actual changes in SCr and urinalysis.PMID:34181718 | DOI:10.1093/ajh/hpab103 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - June 28, 2021 Category: Cardiology Authors: Kyle Ware Vedat Yildiz Min Xiao Ajay Medipally Jessica Hemminger Rachel Scarl Anjali A Satoskar Lee Hebert Iouri Ivanov Laura Biederman Sergey V Brodsky Source Type: research

Decision Tree-Based classification for maintaining normal blood pressure throughout middle age: findings from the Coronary Artery Risk Development in Young Adults study
CONCLUSIONS: This study emphasizes the importance of early life factors to later life systolic BP and support efforts to maintain ideal levels of risk factors for hypertension at young ages. Whether policies to maintain lower BMI and SBP well below the clinical thresholds throughout young adulthood and middle-age can reduce later age hypertension should be examined in future studies.PMID:34175929 | DOI:10.1093/ajh/hpab099 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - June 27, 2021 Category: Cardiology Authors: Orna Reges Amy E Krefman Shakia T Hardy Yuichiro Yano Paul Muntner Donald M Lloyd-Jones Norrina B Allen Source Type: research

Decision Tree-Based classification for maintaining normal blood pressure throughout middle age: findings from the Coronary Artery Risk Development in Young Adults study
CONCLUSIONS: This study emphasizes the importance of early life factors to later life systolic BP and support efforts to maintain ideal levels of risk factors for hypertension at young ages. Whether policies to maintain lower BMI and SBP well below the clinical thresholds throughout young adulthood and middle-age can reduce later age hypertension should be examined in future studies.PMID:34175929 | DOI:10.1093/ajh/hpab099 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - June 27, 2021 Category: Cardiology Authors: Orna Reges Amy E Krefman Shakia T Hardy Yuichiro Yano Paul Muntner Donald M Lloyd-Jones Norrina B Allen Source Type: research

Plasma Adiponectin And Blood Pressure Progression in African Americans: The Jackson Heart Study
CONCLUSIONS: In a large, community-based sample of African Americans, higher adiponectin concentrations were associated with lower risks of BP progression and incident hypertension in men, but no significant association was observed in women.PMID:34166486 | DOI:10.1093/ajh/hpab101 (Source: American Journal of Hypertension)
Source: American Journal of Hypertension - June 24, 2021 Category: Cardiology Authors: Arnaud D Kaze Solomon K Musani Aurelian Bidulescu Adolfo Correa Sherita H Golden Alain G Bertoni Justin B Echouffo-Tcheugui Source Type: research

Circadian Control of Sodium and Blood Pressure Regulation
Am J Hypertens. 2021 Jun 24:hpab100. doi: 10.1093/ajh/hpab100. Online ahead of print.ABSTRACTThe attention for the control of dietary risk factors involved in the development of hypertension, includes a large effort on dietary salt restrictions. Ample studies show the beneficial role of limiting dietary sodium as a lifestyle modification in the prevention and management of essential hypertension. Not until the past decade or so have studies more specifically investigated diurnal variations in renal electrolyte excretion, which led us to the hypothesis that timing of salt intake may impact cardiovascular health and blood pr...
Source: American Journal of Hypertension - June 24, 2021 Category: Cardiology Authors: Reham H Soliman David M Pollock Source Type: research