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A Case-Based Discussion on the Management of Cryptogenic Stroke and Patent Foramen Ovale in the Patient With a Hypercoagulable Disorder
UP TO 40% of all ischemic strokes are considered cryptogenic, implying a stroke without a definitive etiology.1,2 With a dearth of evidence-guided treatment strategies, the literature surrounding cryptogenic stroke is highly variable and not well-standardized. Even though existing guidelines do not specify the exact testing required, the cryptogenic stroke evaluation includes a variety of imaging modalities (eg, echocardiography, angiography, magnetic resonance imaging, carotid ultrasound) and laboratory investigations (eg, genetic testing, hypercoagulable disorder panels, erythrocyte sedimentation rate).
Source: Journal of Cardiothoracic and Vascular Anesthesia - August 27, 2019 Category: Anesthesiology Authors: Neal S. Gerstein, Stacey D. Clegg, Daniel B. Levin, Adam C. Fish, Kirsten Tolstrup, Koki Nakanishi, Yuriko Yoshida, Shunichi Homma Tags: Case Conference Source Type: research
On the Association Between Sleep Quality and Arterial Stiffness: A Population Study in Community-Dwelling Older Adults Living in Rural Ecuador (The Atahualpa Project)
Conclusions:This study shows a significant independent association between the aortic PWV and poor sleep quality in older adults living in rural Ecuador. Results provide more insights into the relevance of the impact of sleep disorders on cardiovascular diseases.Clinical Trial Registration:The Atahualpa Project has been registered atClinicalTrials.gov. The identifier number is NCT01627600, and the date was: 10/02/2012.Citation:Del Brutto OH, Mera RM, Peñaherrera E, Costa AF, Peñaherrera R, Castillo PR. On the association between sleep quality and arterial stiffness: a population study in community-dwelling ol...
Source: Journal of Clinical Sleep Medicine : JCSM - August 14, 2019 Category: Sleep Medicine Source Type: research
Heartburn Drugs May Lead To Allergies, Study Suggests
(CNN) — When heartburn or ulcer pain strikes, drugs can target stomach acid to calm bellies and offer relief. But a new study suggests the medications may come with a hive-inducing side effect: allergies.
After analyzing health insurance data from more than 8 million people in Austria, researchers found that prescriptions of anti-allergy medications surged in those who were prescribed stomach acid inhibitors, a class of drugs that includes proton-pump inhibitors and H2 blockers.
The findings, published Tuesday in the medical journal Nature Communications, suggest that disrupting the stomach’s delicate balance o...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - July 30, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Allergies CNN Heartburn Source Type: news
P42 Age and Education are Associated with Fried Fish Consumption in the Stroke Belt
Fish contain polyunsaturated fatty acids which are associated with decreased cardiovascular (CVD) risk. However, frying fish alters the fatty acids. Consumption of fried fish has been linked to increased risk of CVD and stroke, particularly in populations in the South's Stroke Belt. The purpose of this study was to explore characteristics associated with fried vs. non-fried fish consumption in the rural Appalachian region of the Stroke Belt.
Source: Journal of Nutrition Education and Behavior - June 30, 2019 Category: Nutrition Authors: Frances Hardin-Fanning, Cheryl Witt, Hunter Threadgill Tags: Nutrition Across the Life Cycle Source Type: research
Exposure to water-accommodated fractions of two different crude oils alters morphology, cardiac function and swim bladder development in early-life stages of zebrafish.
Abstract
The present study investigated the developmental toxicity of water-accommodated fractions (WAFs) of Oman crude oil (OCO) and Merey crude oil (MCO) on zebrafish (Danio rerio) in early-life stages (ELS). Based on total petroleum hydrocarbons (TPH), LC50 values manifested that OCO WAF was 1.2-fold more lethal to zebrafish embryos than MCO WAF. As for hatching rate, EC50 value for OCO WAF was 5.7-fold lower than that for MCO WAF. To evaluate the sublethal morphological effects, semi-quantitative extended general morphological score (GMS) and general teratogenic score (GTS) systems were adopted. The GMS and GT...
Source: Chemosphere - June 25, 2019 Category: Chemistry Authors: Li X, Xiong D, Ding G, Fan Y, Ma X, Wang C, Xiong Y, Jiang X Tags: Chemosphere Source Type: research
Preventing and Treating Injuries Caused by Water Sports and Activities
Boating, swimming, fishing and other water sports are popular summertime pursuits but can sometimes have the potential for danger. Here are some tips for dealing with injuries from water activities.
Swimming problems. According to the American Orthopaedic Society for Sports Medicine, most swimming injuries involve the shoulders, back, hips or knees, depending on the individual's stroke. Treatment recommendations from the AOSSM include cutting back on repetitive strokes contributing to overuse, core-strengthening and cross-training exercises, rest periods, alternative training techniques (instead of train...
Source: Advanced Tissue - June 6, 2019 Category: Dermatology Authors: AdvancedTissue Tags: Wound Care Wound Infection Source Type: news
Selenoprotein T as a new positive inotrope in the goldfish, Carassius auratus RESEARCH ARTICLE
This study aimed to evaluate the cardiac expression of SELENOT, and the effects of exogenous PSELT (a 43–52 SELENOT-derived peptide) on the heart function of C. auratus, a hypoxia tolerance fish model. We found that SELENOT was expressed in cardiac extracts of juvenile and adult fish, located in the sarcoplasmic reticulum (SR) together with calsequestrin-2. Expression increased under acute hypoxia. On ex vivo isolated and perfused goldfish heart preparations, under normoxia, PSELT dose dependently increased stroke volume (VS), cardiac output
and stroke work (SW), involving cAMP, PKA, L-type calcium channels, SERCA2...
Source: Journal of Experimental Biology - June 3, 2019 Category: Biology Authors: Mazza, R., Gattuso, A., Imbrogno, S., Boukhzar, L., Leo, S., Mallouki, B. Y., Filice, M., Rocca, C., Angelone, T., Anouar, Y., Cerra, M. C. Tags: RESEARCH ARTICLE Source Type: research
Medical News Today: How a parasitic fish could help us fight brain cancer and stroke
New research in mice suggests that molecules derived from a species of parasitic fish could help tackle cancer and other conditions in the brain.
Source: Health News from Medical News Today - May 19, 2019 Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news
Jawless fish take a bite out of the blood-brain barrier
(University of Wisconsin-Madison) A jawless parasitic fish could help lead the way to more effective treatments for multiple brain ailments, including cancer, trauma and stroke. A team of biomedical engineers and clinician-scientists at the University of Wisconsin-Madison and the University of Texas at Austin borrowed molecules from the immune system of the parasitic sea lamprey to deliver anti-cancer drugs directly to brain tumors.
Source: EurekAlert! - Cancer - May 15, 2019 Category: Cancer & Oncology Source Type: news
Glucosamine supplements may reduce stroke risk
Study finds lower risk of CVD events in users Related items fromOnMedica The new GP contract: transforming primary care, transforming CVD prevention New ‘treadmill test’ can predict mortality Heart disease and stroke deaths plummet in Scotland Public urged to check their ‘heart age’ to prevent premature death Mexican fish offer clues on heart repair
Source: OnMedica Latest News - May 14, 2019 Category: UK Health Source Type: news
Selenoprotein T as a new positive inotrope in the goldfish Carassius auratus RESEARCH ARTICLE
This study aimed to evaluate the cardiac expression of SELENOT, and the effects of exogenous PSELT (a 43-52 SELENOT derived-peptide) on the heart function of C. auratus, a hypoxia tolerance fish model. We found that SELENOT was expressed in cardiac extracts of juvenile and adult fish, located in the sarcoplasmic reticulum (SR) together with calsequestrin-2. Expression increased under acute hypoxia. On ex vivo isolated and perfused goldfish heart preparations, under normoxia, PSELT dose-dependently increased Stroke Volume (SV), Cardiac Output (Q), and Stroke Work (SW), by involving cAMP, PKA, L-type calcium channels, SERCA2...
Source: Journal of Experimental Biology - May 12, 2019 Category: Biology Authors: Rosa, M., Alfonsina, G., Sandra, I., Loubna, B., Serena, L., Yamine, M. B., Mariacristina, F., Carmine, R., Tommaso, A., Youssef, A., Carmela, C. M. Tags: RESEARCH ARTICLE Source Type: research
Intake of 12 food groups and disability-adjusted life years from coronary heart disease, stroke, type 2 diabetes, and colorectal cancer in 16 European countries
AbstractOur aim was to estimate and rank 12 food groups according to disability-adjusted life years (DALYs) from coronary heart disease (CHD), stroke, type 2 diabetes (T2D), and colorectal cancer (CRC) in 16 European countries. De novo published non-linear dose –response meta-analyses of prospective studies (based on 297 primary reports), and food consumption data from the European Food Safety Authority Comprehensive European Food Consumption Database in Exposure Assessment, and DALY estimates from the Institute for Health Metrics and Evaluation were use d. By implementing disease-specific counterfactual scenarios of the...
Source: European Journal of Epidemiology - April 26, 2019 Category: Epidemiology Source Type: research
Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury
Conclusion and Future Aspects
This review summarizes available NTF expression data, compiles existing evidence on the effects of glial NTF signaling in healthy conditions and in disease models (Figure 1), and highlights the importance of this topic for future studies. The relationship between NTFs and glia is crucial for both the developing and adult brain. While some of these factors, such as NT-3 and CNTF, have highly potent effects on gliogenesis, others like BDNF and GDNF, are important for glia-mediated synapse formation.
Neurotrophic factors play significant roles during neurodegenerative disorders. In many cases, ...
Source: Frontiers in Physiology - April 25, 2019 Category: Physiology Source Type: research
Want to Live Longer? Science Says to Do These 5 Things
When it comes to staying healthy, most people have the same motivation: living as long and fulfilling a life as possible. And while science has yet to find a true fountain of youth, researchers have identified certain behaviors that can increase longevity.
One study, published in the journal Circulation last year, even argued that adhering to just five healthy habits could extend your lifespan by roughly a decade. Here’s what they are, and what research to date says about living your longest life.
Eating a healthy diet
Diet is strongly linked to longevity. Research has long suggested that following a Mediterranean di...
Source: TIME: Health - April 19, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Longevity Source Type: news
Rx Fish Oil Cuts Heart Dangers in Statin Takers
The study suggests that the prescription fish oil pill, not to be confused with over-the-counter supplements, reduces the lifetime risk of dying from heart disease; having a non-fatal heart attack or stroke; or needing heart surgery or hospitalization for a heart complication.
Source: WebMD Health - March 18, 2019 Category: Consumer Health News Source Type: news
