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Why You Should Start Thinking About Your Cholesterol Earlier
High cholesterol is known to be one of the primary risk factors for heart disease, since it can contribute to plaque buildup in the arteries. But even though the U.S. Centers for Disease Control and Prevention recommends regular cholesterol testing starting around age 20, many Americans don’t give cholesterol—or heart disease, for that matter—much thought until later in life.
A new modeling study published in the Lancet gives extra reason not to put off cholesterol screening and treatment. It confirms that high blood levels of “bad” (or non-HDL) cholesterol are associated with a greater risk o...
Source: TIME: Health - December 4, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Research Source Type: news
Hypoxic Acclimation Negatively Impacts the Contractility of Steelhead Trout (Oncorhynchus mykiss) Spongy Myocardium.
Abstract
Cardiac stroke volume (SV) is compromised in Atlantic cod and rainbow trout following acclimation to hypoxia (i.e., 40% air saturation; ~ 8 kPa O2) at 10-12oC, and this is not due to changes in heart morphometrics or maximum achievable in vitro end-diastolic volume. To examine if this diminished SVmay be related to compromised myocardial contractility, we used the work loop method to measure work and power in spongy myocardial strips from normoxia- and hypoxia-acclimated steelhead trout when exposed to decreasing PO2levels (21 to 1.5 kPa) at several frequencies (30 - 90 contractions min-1) at 14oC (their ...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - November 19, 2019 Category: Physiology Authors: Carnevale C, Roberts JC, Syme DA, Gamperl AK Tags: Am J Physiol Regul Integr Comp Physiol Source Type: research
FDA Panel: Expand Use of Fish Oil Drug Vascepa
FRIDAY, Nov. 15, 2019 -- Approved use of the prescription-strength fish oil drug Vascepa should be widened to include more patients at risk for heart attack and stroke, a U.S. Food and Drug Administration advisory panel recommended Thursday.
Vascepa...
Source: Drugs.com - Pharma News - November 15, 2019 Category: Pharmaceuticals Source Type: news
A novel cysteine-sparing G73A mutation of NOTCH3 in a Chinese CADASIL family
AbstractCerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic disease leading to stroke and vascular dementia. CADASIL is an inherited small blood vessel disease caused by mutations in the gene encoding the neurogenic locus notch homolog protein 3 (NOTCH3). NOTCH3 is large type I membrane receptor mainly expressed in vascular smooth muscle cells and pericytes. Most identified mutations result in insert or deletion of a cysteine residue within the EGF-like repeats. To date, some cases with a cysteine-sparing mutant have been described. Genetic analy...
Source: Neurogenetics - November 12, 2019 Category: Genetics & Stem Cells Source Type: research
Meat, Fish, and Vegetables: New Data on Heart Disease and Stroke Meat, Fish, and Vegetables: New Data on Heart Disease and Stroke
Dr Christoph Diener on interesting new results in stroke, epilepsy, Duchenne muscular dystrophy, and more.Medscape Neurology
Source: Medscape Neurology and Neurosurgery Headlines - November 2, 2019 Category: Neurology Tags: Neurology & Neurosurgery Commentary Source Type: news
Many take anticoagulants and OTC supplements, which poses risk
FINDINGSNearly 98% percent of people prescribed direct-acting oral anticoagulants such as apixaban also used over-the-counter products. Of those, 33% took at least one such product that, in combination with the anticoagulants, could cause dangerous internal bleeding. People taking these medications largely lacked knowledge of some potentially serious interactions.BACKGROUNDDirect-acting oral anticoagulants are the drug of choice for stroke prevention in patients with atrial fibrillation, which occurs most frequently in older patients. Apixaban is one of the most frequently prescribed. However, most people prescribed apix...
Source: UCLA Newsroom: Health Sciences - October 31, 2019 Category: Universities & Medical Training Source Type: news
External validation of the Vascular Study Group of New England carotid endarterectomy risk predictive model using an independent U.S. national surgical database
Previously, we described a Vascular Study Group of New England (VSGNE) risk predictive model to predict composite adverse outcomes (postoperative death, stroke, myocardial infarction, or discharge to extended care facilities) after carotid endarterectomy (CEA). The goal of this study was to externally validate this model using an independent database.
Source: Journal of Vascular Surgery - October 28, 2019 Category: Surgery Authors: Mohammad H. Eslami, Zein Saadeddin, Alik Farber, Larry Fish, Efthymios D. Avgerinos, Michel S. Makaroun Source Type: research
‘Salty’ Concern: Tackling High Salt Consumption in China
Veena S. Kulkarni, Associate Professor, Department of Criminology, Sociology and Geography, Arkansas State University, USA; and Raghav Gaiha, (Hon.) Professorial Research Fellow, Global Development Institute, University of Manchester, England.By Veena S. Kulkarni and Raghav GaihaNEW DELHI, India and JONESBORO, US, Oct 7 2019 (IPS) China’s almost meteoric transition from a being a low income to a middle income country within a span of four decades is often perceived as a miracle analogous to the post Second World War Japanese economic development experience. China’s GDP rose from $200 current United States dollars (US$ ...
Source: IPS Inter Press Service - Health - October 7, 2019 Category: International Medicine & Public Health Authors: Veena Kulkarni and Raghav Gaiha Tags: Asia-Pacific Development & Aid Economy & Trade Food & Agriculture Food Sustainability Globalisation Headlines Health Labour TerraViva United Nations Barilla Center for Food and Nutrition Foundation (BCFN) Source Type: news
Mediterranean diet: The role of long-chain ω-3 fatty acids in fish; polyphenols in fruits, vegetables, cereals, coffee, tea, cacao and wine; probiotics and vitamins in prevention of stroke, age-related cognitive decline, and Alzheimer disease.
Authors: Román GC, Jackson RE, Gadhia R, Román AN, Reis J
Abstract
The mechanisms of action of the dietary components of the Mediterranean diet are reviewed in prevention of cardiovascular disease, stroke, age-associated cognitive decline and Alzheimer disease. A companion article provides a comprehensive review of extra-virgin olive oil. The benefits of consumption of long-chain ω-3 fatty acids are described. Fresh fish provides eicosapentaenoic acid while α-linolenic acid is found in canola and soybean oils, purslane and nuts. These ω-3 fatty acids interact metabolically with ω-6 fatty acids mainly linoleic...
Source: Revue Neurologique - September 16, 2019 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
Revealing sex-specific molecular changes in hypoxia-ischemia induced neural damage and subsequent recovery using zebrafish model
Publication date: Available online 10 September 2019Source: Neuroscience LettersAuthor(s): Tapatee Das, Kalyani Soren, Mounica Yerasi, Arvind Kumar, Sumana ChakravartyAbstractFunctional recovery from hypoxia-ischemia depends on an individual’s response to the ischemic damage and recovery. Many of the neurological disorders, including cerebral stroke have sex-specific characteristics. Deciphering the differential molecular mechanisms of sex-specific recovery from hypoxic-ischemic insult can improve medical practice in the treatment of cerebral stroke. In the present study, we describe the establishment of a sex-specific g...
Source: Neuroscience Letters - September 12, 2019 Category: Neuroscience Source Type: research
Study Reveals Mixed Effects on Health for Vegetarian Diet
FRIDAY, Sept. 6, 2019 -- Vegetarians and fish eaters have a lower risk for ischemic heart disease compared with meat eaters, and vegetarians have a higher risk for stroke, according to a study published online Sept. 4 in The BMJ.
Tammy Y.N. Tong,...
Source: Drugs.com - Pharma News - September 6, 2019 Category: Pharmaceuticals Source Type: news
Vegetarians May Face Higher Stroke Risk
While vegetarians had a 22% lower risk for heart disease, they had a 20% higher risk for stroke, British researchers found. Meanwhile, people who ate fish but no other meats (pescatarians) had a 13% lower risk of heart disease, with no increased stroke risk.
Source: WebMD Health - September 5, 2019 Category: Consumer Health News Source Type: news
Vegetarians May Be At Higher Risk Of Stroke, Study Finds
BOSTON (CBS) – Many people adopt a vegetarian lifestyle to help reduce their risk of cardiovascular disease, but a new study published in the BMJ finds people who avoid meat all together may be at a higher risk of stroke.
Researchers in the U.K. looked at about 48 thousand adults over 18 years. They found that vegetarians, vegans, and pescatarians (people who eat fish but not meat) had a lower risk of ischemic heart disease, like heart attacks. But vegetarians had a 20% higher risk of stroke compared to meat eaters.
It’s not clear why vegetarians may suffer more strokes. Perhaps it is due to lower levels of cer...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 5, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated Local Dr. Mallika Marshall Stroke Vegetarian Source Type: news
A New Study Suggests Vegetarians and Vegans Are at Higher Risk of Stroke. But Don ’t Reach for That Steak Just Yet
Vegetarians and vegans are likely to be concerned by the results of a new study with a surprising finding: those following meat-free diets, which are typically associated with better cardiovascular health, may actually have a higher risk of stroke than those who eat meat.
But it’s too soon to run out and order a steak. The paper, published in the BMJ, found only a small increase in the risk of stroke, while confirming findings in other studies that vegetarians and vegans may have a lower risk of heart disease than meat-eaters.
“It’s important to emphasize that we’ve looked at two outcomes here,R...
Source: TIME: Health - September 5, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Diet/Nutrition onetime Source Type: news
Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study
Source: BMJ - September 5, 2019 Category: General Medicine Source Type: research
