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Total 137 results found since Jan 2013.

How to Keep Alzheimer ’s From Bringing About the Zombie Apocalypse
I tried to kill my father for years. To be fair, I was following his wishes. He’d made it clear that when he no longer recognized me, when he could no longer talk, when the nurses started treating him like a toddler, he didn’t want to live any longer. My father was 58 years old when he was diagnosed with Alzheimer’s disease. He took the diagnosis with the self-deprecating humor he’d spent a lifetime cultivating, constantly cracking jokes about how he would one day turn into a zombie, a walking corpse. We had a good 10 years with him after the diagnosis. Eventually, his jokes came true. Seven years ...
Source: TIME: Science - November 20, 2019 Category: Science Authors: Jay Newton-Small Tags: Uncategorized Alzheimer's Disease Source Type: news

‘Salty’ Concern: Tackling High Salt Consumption in China
Veena S. Kulkarni, Associate Professor, Department of Criminology, Sociology and Geography, Arkansas State University, USA; and Raghav Gaiha, (Hon.) Professorial Research Fellow, Global Development Institute, University of Manchester, England.By Veena S. Kulkarni and Raghav GaihaNEW DELHI, India and JONESBORO, US, Oct 7 2019 (IPS) China’s almost meteoric transition from a being a low income to a middle income country within a span of four decades is often perceived as a miracle analogous to the post Second World War Japanese economic development experience. China’s GDP rose from $200 current United States dollars (US$ ...
Source: IPS Inter Press Service - Health - October 7, 2019 Category: International Medicine & Public Health Authors: Veena Kulkarni and Raghav Gaiha Tags: Asia-Pacific Development & Aid Economy & Trade Food & Agriculture Food Sustainability Globalisation Headlines Health Labour TerraViva United Nations Barilla Center for Food and Nutrition Foundation (BCFN) Source Type: news

High Intake of Free Sugars, Fructose, and Sucrose Is Associated with Weight Gain in Japanese Men
ConclusionsThese results suggested that high intakes of free sugars, sucrose, and fructose were associated with long-term weight gain among Japanese men.
Source: Journal of Nutrition - September 16, 2019 Category: Nutrition Source Type: research

Seaweed intake and risk of cardiovascular disease: the Japan Public Health Center-based Prospective (JPHC) Study.
CONCLUSIONS: Seaweed intake was inversely associated with risk of ischemic heart disease. PMID: 31518387 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - September 12, 2019 Category: Nutrition Authors: Murai U, Yamagishi K, Sata M, Kokubo Y, Saito I, Yatsuya H, Ishihara J, Inoue M, Sawada N, Iso H, Tsugane S, JPHC Study Group Tags: Am J Clin Nutr Source Type: research

Ramen restaurant prevalence is associated with stroke mortality in Japan: an ecological study
The association between stroke and nutrition has recently been investigated. However, the association between diet and stroke in Japan has not been clarified. We hypothesized that there may be an association b...
Source: Nutrition Journal - September 4, 2019 Category: Nutrition Authors: Kosuke Matsuzono, Makiko Mieno and Shigeru Fujimoto Tags: Research Source Type: research

Getting Your Protein From Plants May Help You Live Longer
Japanese men and women who consumed the most plant proteins had a lower rate of cardiovascular death and stroke.
Source: NYT Health - September 3, 2019 Category: Consumer Health News Authors: Nicholas Bakalar Tags: Heart Longevity Deaths (Fatalities) Veganism Vegetables Diet and Nutrition Source Type: news

Ezetimibe Lipid-Lowering Trial on Prevention of Atherosclerotic Cardiovascular Disease in 75 or Older (EWTOPIA 75): A Randomized Controlled Trial.
CONCLUSIONS: LDL-C-lowering therapy with ezetimibe prevented cardiovascular events, suggesting the importance of LDL-C lowering for primary prevention in individuals aged ≥75 years with elevated LDL-C. Given the open label nature of the trial, its premature termination and issues with follow up, the magnitude of benefit observed should be interpreted with caution. CLINICAL TRIAL REGISTRATION: URL: https://www.umin.ac.jp Unique identifier: UMIN000001988. PMID: 31434507 [PubMed - as supplied by publisher]
Source: Circulation - August 21, 2019 Category: Cardiology Authors: Ouchi Y, Sasaki J, Arai H, Yokote K, Harada K, Katayama Y, Urabe T, Uchida Y, Hayashi M, Yokota N, Nishida H, Otonari T, Arai T, Sakuma I, Sakabe K, Yamamoto M, Kobayashi T, Oikawa S, Yamashita S, Rakugi H, Imai T, Tanaka S, Ohashi Y, Kuwabara M, Ito H Tags: Circulation Source Type: research

Nationwide Actions Against Heart Failure Pandemic in Japan 　- What Should We Do From Academia?
Nationwide Actions Against Heart Failure Pandemic in Japan　- What Should We Do From Academia? Circ J. 2019 Aug 06;: Authors: Komuro I, Kaneko H, Morita H, Isobe M, Nakayama H, Minematsu K, Yamaguchi T, Yazaki Y Abstract Heart failure pandemic is rapidly approaching in Japan, requiring nationwide actions. In particular, the Japanese Circulation Society and related societies launched the Stroke and Cardiovascular Disease Control Act, which was passed by the National Diet, as the first ever legislative policy measure against stroke and cardiovascular disease. In association with this, actions against h...
Source: Circulation Journal - August 5, 2019 Category: Cardiology Authors: Komuro I, Kaneko H, Morita H, Isobe M, Nakayama H, Minematsu K, Yamaguchi T, Yazaki Y Tags: Circ J Source Type: research

Associations between coffee consumption and all-cause and cause-specific mortality in a Japanese city: the Takayama study.
CONCLUSION: Drinking coffee, even 1 cup/d, was inversely associated with all-cause mortality and mortality from cardiovascular, infectious and digestive diseases. PMID: 31107195 [PubMed - as supplied by publisher]
Source: Public Health Nutrition - May 19, 2019 Category: International Medicine & Public Health Authors: Yamakawa M, Wada K, Goto Y, Mizuta F, Koda S, Uji T, Nagata C Tags: Public Health Nutr Source Type: research

Dietary Inflammatory Index Is Associated with Risk of All-Cause and Cardiovascular Disease Mortality but Not with Cancer Mortality in Middle-Aged and Older Japanese Adults
ConclusionOur findings suggest that a higher DII was associated with an increased risk of all-cause and CVD mortality among Japanese adults.
Source: Journal of Nutrition - May 17, 2019 Category: Nutrition Source Type: research

NAMPT as a Dedifferentiation-Inducer Gene: NAD+ as Core Axis for Glioma Cancer Stem-Like Cells Maintenance
Conclusion and Perspectives Gliomas are the most prevalent primary brain cancer in adults and include a broad category of tumors including astrocytoma, oligodendroglioma, and GBM. Regardless of tumor aggressiveness, malignancy, and infiltration, these glia-derived tumors rarely exceed a median survival time of 12–14 months. Driven by the infiltrative nature of these tumors, the clinical approach is difficult and relapses often occur with fatal consequences. These unsuccessful attempts to control glioma's fate have fostered research looking for more effective therapies. (GSCs) are a small subset of CD133&#...
Source: Frontiers in Oncology - May 2, 2019 Category: Cancer & Oncology Source Type: research

Orally Administered Crocin Protects Against Cerebral Ischemia/Reperfusion Injury Through the Metabolic Transformation of Crocetin by Gut Microbiota
Conclusion Collectively, pharmacokinetic and pharmacodynamic association studies provide evidence that the gut microbiota plays a vital role in the fate of crocin and crocetin in the gastrointestinal tract. In addition, the cross-interaction between gut microbiota and crocin might mediate the activation of the cerebral-protective effect of orally administered crocin. Ethics Statement This study was carried out in accordance with the recommendations of ‘Institutional Animal Research Committee guidelines, Animal Ethics Committee of China Pharmaceutical University.’ The protocol was approved by the ‘An...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Harnessing the Four Elements for Mental Health
DiscussionAs detailed above, the “elements” in both a classical and a contemporary sense have effects on our mental health and are potentially modifiable aspects that can be harnessed as therapeutic interventions. The most robust interventional evidence currently available shows tentative support for several use of the elements via horticultural and nature-exposure therapy, green exercise/physical activity, sauna and heat therapy, balneotherapy, and breathing exercises. It should be noted that, in many cases, these interventions were not studied in definitive diagnosed psychiatric disorders and thus it is pre...
Source: Frontiers in Psychiatry - April 23, 2019 Category: Psychiatry Source Type: research

Modifiable Lifestyle Factors and Cognitive Function in Older People: A Cross-Sectional Observational Study
Conclusions: Lifestyle factors, such as physical activity, sleep, and social activity appear to be associated with cognitive function among older people. Physical activity and appropriate durations of sleep and conversation are important for cognitive function. Introduction Dementia is a major public health issue worldwide, with a serious burden for patients, caregivers, and society, as well as substantial economic impacts (1). Although the prevalence of late-life cognitive impairment and dementia are expected to increase in future, effective disease-modifying treatments are currently unavailable. Therefore, unders...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Osteoporosis and Sarcopenia Increase Frailty Syndrome in the Elderly
Conclusions World population is aging and the increase in life expectancy is often unhealthy. In particular, musculoskeletal aging, which leads to sarcopenia and osteoporosis, has several causes such as changes in body composition, inflammation, and hormonal imbalance. Sarcopenia, osteoporosis, and more frequently, sarcopenic obesity are commonly associated with aging and frequently closely linked each other, often leading to the development of a frailty syndrome. Frailty syndrome favors an increased risk of loss function in daily activities, for cardiovascular diseases, cancers, falls, and mortality. As the number of eld...
Source: Frontiers in Endocrinology - April 23, 2019 Category: Endocrinology Source Type: research