Modifiable Lifestyle Factors and Cognitive Function in Older People: A Cross-Sectional Observational Study

Conclusions: Lifestyle factors, such as physical activity, sleep, and social activity appear to be associated with cognitive function among older people. Physical activity and appropriate durations of sleep and conversation are important for cognitive function. Introduction Dementia is a major public health issue worldwide, with a serious burden for patients, caregivers, and society, as well as substantial economic impacts (1). Although the prevalence of late-life cognitive impairment and dementia are expected to increase in future, effective disease-modifying treatments are currently unavailable. Therefore, understanding the modifiable risk factors and developing evidence-based interventions for delaying or preventing cognitive impairment is an important challenge. Numerous observational studies have reported a range of potentially modifiable risk factors for dementia, including lower levels of education, midlife hypertension, midlife obesity, diabetes mellitus, smoking, and late-life depression, as well as social isolation, physical inactivity, and hearing loss (2–6). Depression, physical inactivity, and social isolation are particularly important predictors of late-life cognitive impairment (4, 7). Sleep disturbance is also prevalent among older people, representing a risk factor for cognitive impairment (8–11). However, most previous studies have used self-report questionnaires, which can have problems with reliability and consistency due to recall bia...
Source: Frontiers in Neurology - Category: Neurology Source Type: research

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CONCLUSIONS: Gaps in memory and various memory types were common after ICU admission, whose prevalence waned over time. Compared with nightmares and fearful memories, gaps in memories were most strongly associated with poor mental health and quality of life. Identifying patients with gaps in memories might be an objective way of planning interventions to improve their long-term outcomes.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research
OBJECTIVES: We performed a comprehensive health assessment in mechanically ventilated coronavirus disease 2019 survivors to assess the impact of respiratory and skeletal muscle injury sustained during ICU stay on physical performance at 3 months following hospital discharge. DESIGN: Preregistered prospective observational cohort study. SETTING: University hospital ICU. PATIENTS: All mechanically ventilated coronavirus disease 2019 patients admitted to our ICU during the first European pandemic wave. MEASUREMENTS AND MAIN RESULTS: At 3 months after hospital discharge, 46 survivors underwent a...
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Clinical investigations Source Type: research
We examined the incidence and impact of early multiple organ dysfunction syndrome on clinical, functional, and disability outcomes over the year following traumatic brain injury. DESIGN: Retrospective cohort study. SETTING: Patients enrolled in the Transforming Clinical Research and Knowledge in Traumatic Brain Injury study, an 18-center prospective cohort study of traumatic brain injury patients evaluated in participating level 1 trauma centers. SUBJECTS: Adult (age> 17 yr) patients with moderate-severe traumatic brain injury (Glasgow Coma Scale
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Neurologic Critical Care Source Type: research
AbstractEndometritis in dairy cows is a major economic problem worldwide; without advances in lifestyle management and drug treatment, it causes high morbidity and death. Micro ribonucleic acid (miRNAs) these days is seen as an important part of gene control networks. It is a class of small nucleotides 20 –25, single-stranded RNA molecules. In endometritis, the inflammatory response caused by the gram-negative bacteriaEscherichia coli (E. coli) alters the expression of miRNA which can regulate the innate immune system. This manuscript reviews (1) the interaction of miRNAs with the signaling of NF- κB and dysreg...
Source: Inflammation - Category: Allergy & Immunology Source Type: research
If it hurts – take notice, and avoid it. Learn from it. If there are other people around, make sure your behaviour is noticeable so they take care of you and don’t do what you just did. If they look after you, you’ll probably do the same thing again when you hurt, if they don’t you probably won’t. This is one description of pain behaviour and how it works. It’s the only part of our pain experience that we can share directly with one another (actions and words). The “doing” part is also the part that is most affected by pain – even distress is signalled to others &nd...
Source: HealthSkills Weblog - Category: Anesthesiology Authors: Tags: Uncategorized Chronic pain Clinical reasoning pain management Research Source Type: blogs
Source: Vascular Health and Risk Management - Category: Cardiology Tags: Breast Cancer: Targets and Therapy Source Type: research
Hello, I’m a PGY3 Neurology resident applying fir fellowship this year. I am thinking between Neuro-Ophthalmology (because is chill and lux and have good life style) epilepsy (because I think it might be good job opportunities) and vascular (field that I’ve done alot of research projects in and initially was my favorite but I’m not a fan if life style and being oncall anymore) I recently heard that neuromuscular has the best job market among all of sub-specialities in neurology. I would... Read more
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Neurology Source Type: forums
List of hints and tips on how to enjoy a healthier, happier life based on recent research that applies to people of all ages
Source: Disabled World - Category: Disability Tags: Fitness - Nutrition Source Type: news
HYPERTENSION more commonly known as high blood pressure affects millions of Britons. Your diet can have a huge impact on your blood pressure reading, but could just one teaspoon slash your risk?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Source: BMJ Comments - Category: General Medicine Source Type: forums
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