Modifiable Lifestyle Factors and Cognitive Function in Older People: A Cross-Sectional Observational Study

Conclusions: Lifestyle factors, such as physical activity, sleep, and social activity appear to be associated with cognitive function among older people. Physical activity and appropriate durations of sleep and conversation are important for cognitive function. Introduction Dementia is a major public health issue worldwide, with a serious burden for patients, caregivers, and society, as well as substantial economic impacts (1). Although the prevalence of late-life cognitive impairment and dementia are expected to increase in future, effective disease-modifying treatments are currently unavailable. Therefore, understanding the modifiable risk factors and developing evidence-based interventions for delaying or preventing cognitive impairment is an important challenge. Numerous observational studies have reported a range of potentially modifiable risk factors for dementia, including lower levels of education, midlife hypertension, midlife obesity, diabetes mellitus, smoking, and late-life depression, as well as social isolation, physical inactivity, and hearing loss (2–6). Depression, physical inactivity, and social isolation are particularly important predictors of late-life cognitive impairment (4, 7). Sleep disturbance is also prevalent among older people, representing a risk factor for cognitive impairment (8–11). However, most previous studies have used self-report questionnaires, which can have problems with reliability and consistency due to recall bia...
Source: Frontiers in Neurology - Category: Neurology Source Type: research

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CONCLUSION: This study confirmed published results that labour progresses more slowly as maternal BMI increases. The study was performed in a centre with a specialized BMI pregnancy clinic; thus weight gain adherence, awareness of labour differences, and patient counselling may have contributed to low Caesarean section rates. Obstetric care providers should consider differences in maternal BMI in labour progression before undertaking a potentially premature Caesarean birth, especially in primiparas. PMID: 31324481 [PubMed - as supplied by publisher]
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
In this study, the effects of dietary administration of lactic acid bacteria (LAB) (Enterococcus faecalis Y17 and Pediococcus pentosaceus G11) on growth performance and immune responses of mud crab were assessed. Both strains (Y17 and G11) showed an inhibitory activity against bacterial pathogens (Aeromonas hydrophila, Vibrio parahaemolyticus, Vibrio alginolyticus, Staphylococcus aureus, and β Streptococcus), and a wide pH tolerance range of 2–10. In vivo, mud crabs were fed a control diet and experimental diets supplemented with 109 cfu g−1 diet either Y17 or G11 for 6 weeks before subjecting to a cha...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: December 2019Source: Protein Expression and Purification, Volume 164Author(s): Elisabeth Graeber, Volodymyr M. KorkhovAbstractThe translocator protein TSPO is in an important diagnostic and therapeutic target in a range of pathologies, including neuroinflammation and cancer. Despite the availability of several structures of TSPO homologues, our understanding of the molecular determinants that govern high-affinity interactions of TSPO with its ligands is incomplete. Here, in order to decipher the key structural elements of TSPO responsible for interactions with its ligands, we designed a panel of chimeric ...
Source: Protein Expression and Purification - Category: Biochemistry Source Type: research
Publication date: Available online 20 July 2019Source: Advances in Life Course ResearchAuthor(s): Scott D. Landes, Richard A. SetterstenAbstractThe notion that people make choices and take actions that determine the outcomes of their lives – human agency – is a central principle of the life course paradigm. Unfortunately, conceptualizations of agency, like larger developmental and sociological theories, often assume that agency is limited to individuals who are “developmentally normal.” We draw upon the thought of social scientists and disability scholars, as well as the life history of a woman with...
Source: Advances in Life Course Research - Category: Reproduction Medicine Source Type: research
This is a guest post from one of our patients. She is 32 and recently froze her eggs at Malpani Infertility ClinicOur 20 ’s and early 30's may be theeasiest time to have a baby but it's not always the best time - for a lot of good reasons. We are at the top of our career and want to grow professionally; we want to prepare emotionally and financially to be parents ; and we are unwilling to settle for Mr. RightNow instead of Mr. Right.The problem is that the biological clock is ticking on - and we can hear it loud and clear ! The good news is that with a little medical help , we can freeze time , to plan for the future...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
ConclusionLicensed drivers with ASD were found to allocate visual attention differently compared to licensed drivers without ASD. Poor scanning patterns with an over-focus on the road ahead and less scanning of the road side and periphery may possibly result in unsafe driving. However, risk-taking behaviour was not prevalent in these drivers. Effective visual scanning strategies could be incorporated in the driver training of individuals with ASD.
Source: Journal of Transport and Health - Category: Occupational Health Source Type: research
I’ve scanned through and haven’t found a post that seems to fully answer my question. I have about $150,00 in student loans left, all of which are federal. When I first graduated I picked the 25 year extended payment plan. I decided not to do IBR because the payments were about the same and I assumed my income would increase. Since this will now be year 3 without a raise or bonus, does it make sense to backtrack and sign up for IBR? I picked the plan I did with the intent to pay extra and... IBR? Loan advice?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pharmacy Source Type: forums
Source: ClinicoEconomics and Outcomes Research - Category: Health Management Tags: ClinicoEconomics and Outcomes Research Source Type: research
Long time lurker here cGPA: 3.8 sGPA: 3.76 MCAT: 522 (129/130/131/132) Ethnicity: Hispanic (Puerto-Rican) State of Residence: NY, grew up in a poor, heavily Hispanic inner-city neighborhood. Parents never went to college, disadvantaged. ECs: -Clinical: Oncology floor volunteer (100 hr), surgical floor volunteer (60 hr), Psychiatric clinic volunteer (35 hr), stroke/spinal trauma unit volunteer (35 hr) -Nonclinical: 200+ hr in city-wide volunteer program that connects you with different... 3.8 GPA, 522 MCAT and URM/SES-Disadvantaged/First Gen... But a few red flags on app?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: What Are My Chances? WAMC Medical Source Type: forums
Source: ClinicoEconomics and Outcomes Research - Category: Health Management Tags: ClinicoEconomics and Outcomes Research Source Type: research
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