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High-Fiber Diet Linked To Lower Risk Of Death And Chronic Illness
(CNN) — People who eat diets that are high in fiber have lower risk of death and chronic diseases such as stroke or cancer compared with people with low fiber intake, a new analysis found. Dietary fiber includes plant-based carbohydrates such as whole-grain cereal, seeds and some legumes. Fiber’s health benefits have been recorded “by over 100 years of research,” Andrew Reynolds, a researcher at the University of Otago in New Zealand, wrote in an email. He is co-author of the new meta-analysis of existing research, which was published Thursday in the journal The Lancet. The research shows that high...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 11, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN fiber Local TV Source Type: news

Carbohydrate quality and human health: a series of systematic reviews and meta-analyses
Publication date: Available online 10 January 2019Source: The LancetAuthor(s): Andrew Reynolds, Jim Mann, John Cummings, Nicola Winter, Evelyn Mete, Lisa Te MorengaSummaryBackgroundPrevious systematic reviews and meta-analyses explaining the relationship between carbohydrate quality and health have usually examined a single marker and a limited number of clinical outcomes. We aimed to more precisely quantify the predictive potential of several markers, to determine which markers are most useful, and to establish an evidence base for quantitative recommendations for intakes of dietary fibre.MethodsWe did a series of systema...
Source: The Lancet - January 11, 2019 Category: General Medicine Source Type: research

Want to Prevent the Deadliest Diseases? Eat More Fiber
If you want to eat something for better health, make it fiber. That’s the advice from nutrition experts and the latest national dietary guidelines. Now, a large new review of studies on fiber, published in the Lancet, shows just how beneficial fiber can be. The nutrient substantially lowers the risk of at least four diseases—many of which don’t even directly relate to the gut. Compared to those who ate less fiber, people who ate more fiber lowered their risk of heart disease, stroke, type 2 diabetes and colon cancer, as well as their risk of dying early from any cause, by 15% to 30%. And the more dietary ...
Source: TIME: Health - January 10, 2019 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Cancer Diet/Nutrition healthytime Heart Disease Source Type: news

Image-based screening.
Abstract Screening is a special issue in medical questions concerning disease prevention. Preconditions for screening are clearly defined by the World Health Organization. High prevalence, effectiveness of therapy, availability of accepted test procedure and consensus concerning the economic concerns are necessary for successful implementation of a screening program. Preventive diagnostic studies can only be understood if one is familiar with the statistical terms sensitivity, specificity, prevalence, incidence and bias (especially overdiagnosis and lead time bias). Aspects of radiation protection are especially...
Source: Der Radiologe - December 14, 2018 Category: Radiology Authors: Layer G Tags: Radiologe Source Type: research

Home Based Primary Care for Patients with Sickle Cell Disease
Conclusion: Overall, home based primary care seems to be a promising alternative for pts with SCD. It had a significant impact on patient quality of care and may improve prescription adherence, but more data are needed to determine if it has an effect on healthcare utilization for pts with SCD.DisclosuresMoore: Ohio State University College of Medicine: Research Funding. Desai: FDA: Research Funding; Pfizer: Research Funding; University of Pittsburgh: Research Funding; Selexy/Novartis: Research Funding; NIH: Research Funding; Ironwood: Other: Adjudication Committee.
Source: Blood - November 21, 2018 Category: Hematology Authors: Moore, M. D., Schamess, A., Williams, N., Huang, Y., Menka, G., Desai, P. C. Tags: 901. Health Services Research-Non-Malignant Conditions: Poster III Source Type: research

Monoclonal Gammopathy of Undetermined Significance - Patient Characteristics and Referral Patterns
ConclusionMGUS is often incidentally detected as part of a work up for other medical conditions, and our results reveal that there is a variety of reasons for which monoclonal testing is performed. With recent developments in our understanding of the significance of monoclonal gammopathy and its association with certain renal and organ damage (Fermand et al., 2018; Leung et al., 2012), there may be a change in how the paraproteinemia investigations are utilized by clinicians in different disciplines. It will be important to recognize and establish appropriate indications for testing. Furthermore, MGUS patients present with...
Source: Blood - November 21, 2018 Category: Hematology Authors: Lee, H., Street, L., Tay, J., Grossman, J., Thaell, J. F., Goodyear, D., McCulloch, S., Duggan, P., Neri, P., Jimenez-Zepeda, V. Tags: 651. Myeloma: Biology and Pathophysiology, excluding Therapy: Poster III Source Type: research

Biomarkers and potential pathogenesis of colorectal cancer-related ischemic stroke.
CONCLUSION: Hypercoagulability induced by elevated CEA and neutrophils may be an important cause of CRCIS. The CRCIS index, which serves as a biomarker of CRCIS, needs further study. PMID: 30487704 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - November 21, 2018 Category: Gastroenterology Authors: Qin QX, Cheng XM, Lu LZ, Wei YF, Wang DC, Li HH, Li GH, Liang HB, Li SY, Chen L, Liang ZJ Tags: World J Gastroenterol Source Type: research

Should You Take Aspirin Every Day? Here ’s What the Science Says
Aspirin is best known as an over-the-counter painkiller. But acetylsalicylic acid, as it’s called chemically, has many other health benefits, as well as side effects, in the body that have only become clear in recent years. Here’s what the latest science says about the health benefits and side effects of aspirin, as well as which conditions it may treat and those it doesn’t appear to improve. (If you are taking aspirin for any reason other than for periodic pain relief, it’s best to consult with your doctor to confirm whether the benefits outweigh the risks in your particular case.) How aspirin affe...
Source: TIME: Health - November 8, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized Drugs healthytime Source Type: news

Physical activity participation and the risk of chronic diseases among South Asian adults: protocol for a systematic review and meta-analysis
DiscussionThis review will summarise the strength of the association between physical activity and selected chronic diseases and their markers among South Asian adults 40  years or older. The findings will provide an evidence base to guide public health policy and interventions in the South Asian region and to inform future research to address the rising burden of chronic diseases.Systematic review registrationPROSPEROCRD42018096505
Source: Systematic Reviews - October 30, 2018 Category: International Medicine & Public Health Source Type: research

Efficacy and Safety of Rivaroxaban versus Warfarin in Patients with Nonvalvular Atrial Fibrillation and a History of Cancer: Observations from ROCKET AF.
Conclusion: In ROCKET AF, a history of cancer was associated with a higher risk of bleeding and non-cardiovascular death, but not ischemic events. The relative efficacy and safety of rivaroxaban compared with warfarin were not significantly different in patients with and without a history of cancer. The results of this study are exploratory and should be taken in context of the study population, which may not be generalizable to those with advanced malignancy. Further investigation is needed to understand optimal anticoagulation strategies in patients with AF and cancer. PMID: 30219887 [PubMed - as supplied by publisher]
Source: Clinical Genitourinary Cancer - September 14, 2018 Category: Cancer & Oncology Authors: Chen ST, Hellkamp AS, Becker RC, Berkowitz SD, Breithardt G, Fox KAA, Hacke W, Halperin JL, Hankey GJ, Mahaffey KW, Nessel CC, Piccini JP, Singer DE, Patel MR, Melloni C Tags: Eur Heart J Qual Care Clin Outcomes Source Type: research

Cancer Will Kill Nearly 10 Million People This Year, Report Estimates
(CNN) — The number of people around the world who have cancer is “rapidly growing,” with 18.1 million new cases and 9.6 million deaths in 2018 alone, researchers estimate in a new report. By the end of the century, cancer will be the No. 1 killer globally and the single biggest barrier to increasing our life expectancy, according to the report, released Wednesday by the World’s Health Organization’s International Agency for Research on Cancer. Cancer by the numbers The researchers used data from 185 countries, looking at all the places in the body cancer can occur and taking a deeper look at 3...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 12, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Cancer Local TV Source Type: news

Pattern of mortality after menopausal hormone therapy: long-term follow-up in a population based cohort.
CONCLUSIONS: In this long-term follow-up study, taking hormones during menopause was not associated with overall mortality among middle-aged women. Investigating cause-specific mortality revealed significant albeit weak associations differential according to both causes of death and over time underlining the importance of carefully considering individual risks and duration of treatment when making decisions on hormone therapy. This article is protected by copyright. All rights reserved. PMID: 30106241 [PubMed - as supplied by publisher]
Source: BJOG : An International Journal of Obstetrics and Gynaecology - August 14, 2018 Category: OBGYN Authors: Holm M, Olsen A, Au Yeung SL, Overvad K, Lidegaard Ø, Kroman N, Tjønneland A Tags: BJOG Source Type: research

Dietary Magnesium and Chronic Disease
Publication date: May 2018Source: Advances in Chronic Kidney Disease, Volume 25, Issue 3Author(s): Forrest H. NielsenAlthough official magnesium (Mg) dietary reference intakes are open to question, a significant number of adults likely have intakes that are in the range of 50%-99% of the requirement. This moderate or marginal (subclinical) deficient Mg intake generally is asymptomatic. Animal studies, however, indicate that moderate or subclinical Mg deficiency primes phagocytic cells for the release of proinflammatory cytokines leading to chronic inflammatory and oxidative stress. Human studies have found that dietary Mg ...
Source: Advances in Chronic Kidney Disease - July 10, 2018 Category: Urology & Nephrology Source Type: research