Monoclonal Gammopathy of Undetermined Significance - Patient Characteristics and Referral Patterns

ConclusionMGUS is often incidentally detected as part of a work up for other medical conditions, and our results reveal that there is a variety of reasons for which monoclonal testing is performed. With recent developments in our understanding of the significance of monoclonal gammopathy and its association with certain renal and organ damage (Fermand et al., 2018; Leung et al., 2012), there may be a change in how the paraproteinemia investigations are utilized by clinicians in different disciplines. It will be important to recognize and establish appropriate indications for testing. Furthermore, MGUS patients present with a wide range of comorbidities at the time of diagnosis. Interdisciplinary care will play a key role in discerning how much of the organ dysfunction and patients' symptoms are secondary to their underlying medical conditions versus the effect of monoclonal gammopathy.DisclosuresMcCulloch: Celgene: Honoraria; Takeda: Other: Travel expenses. Neri: Celgene: Consultancy, Honoraria; Janssen: Consultancy, Honoraria.
Source: Blood - Category: Hematology Authors: Tags: 651. Myeloma: Biology and Pathophysiology, excluding Therapy: Poster III Source Type: research

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Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research
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