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Hormone therapy in the postmenopausal years: considering benefits and risks in clinical practice
AbstractBACKGROUNDMenopausal symptoms can be very distressing and considerably affect a woman ’s personal and social life. It is becoming more and more evident that leaving bothersome symptoms untreated in midlife may lead to altered quality of life, reduced work productivity and, possibly, overall impaired health. Hormone therapy (HT) for the relief of menopausal symptoms has been the obj ect of much controversy over the past two decades. At the beginning of the century, a shadow was cast on the use of HT owing to the concern for cardiovascular and cerebrovascular risks, and breast cancer, arising following publication ...
Source: Human Reproduction Update - August 25, 2021 Category: OBGYN Source Type: research

Patient Preferences of Low-Dose Aspirin for Cardiovascular Disease and Colorectal Cancer Prevention in Italy: A Latent Class Analysis
ConclusionPatient preferences for the benefits and risks of low-dose aspirin differ significantly among people eligible for treatment as primary or secondary CVD prevention.
Source: The Patient - Patient-Centered Outcomes Research - August 19, 2021 Category: International Medicine & Public Health Source Type: research

The impact of seven major noncommunicable diseases on direct medical costs, absenteeism, and presenteeism in Gulf Cooperation Council countries
CONCLUSION: The economic burden of noncommunicable diseases in Gulf Cooperation Council countries is substantial, suggesting that successful preventive interventions have the potential to improve both population health and reduce costs. Further research is needed to capture a broader array of noncommunicable diseases and to develop more precise estimates.PMID:34138664 | DOI:10.1080/13696998.2021.1945242
Source: Journal of Medical Economics - June 17, 2021 Category: Health Management Authors: Eric Andrew Finkelstein Jesse D Malkin Drishti Baid Ada Alqunaibet Khaled Mahdi Mohammed Bin Hamad Al-Thani Buthaina Abdulla Bin Belaila Ebrahim Al Nawakhtha Saleh Alqahtani Sameh El-Saharty Christopher H Herbst Source Type: research

Association of physical activity with stroke among long-term colorectal cancer survivors
ConclusionsModerate frequency of moderate-to-vigorous physical activity (5-9 time/week) and walking (4-5 time/week) significantly lowers the risk of stroke, whereas high-frequency physical activity reduces the benefits of physical activity.Implications for Cancer SurvivorsPhysical activity with moderate frequency is important in the prevention of stroke for long-term colorectal cancer survivors.
Source: Journal of Cancer Survivorship - June 17, 2021 Category: Cancer & Oncology Source Type: research

Opportunities and limitations of risk adjustment of quality indicators based on inpatient administrative health data - a workshop report
DISCUSSION: Implementing specific risk adjustment models had only minor effects on the distribution of risk-adjusted mortality compared to the standard procedure, but the judgement of quality of care could change for a fifth of the hospitals in individual indicators. Concerning methodological and practical reasons, the task force recommends further development of risk adjustment methods for selected indicators. This should be accompanied by studies on the validity of inpatient administrative data for quality management as well as by efforts to improve the usefulness of these data for such purposes.PMID:34023246 | DOI:10.10...
Source: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen - May 23, 2021 Category: Health Management Authors: Daniel Schwarzkopf Ulrike Nimptsch Raphael Graf Jochen Schmitt Josef Zacher Ralf Kuhlen Source Type: research

Implementation of Oral Anticoagulation Treatment Guidelines in Patients with Newly Diagnosed Atrial Fibrillation
CONCLUSION: Despite the increasing OAC treatment rates among high risk AF patients, mainly attributed to the expanding DOAC use, OAC treatment scope is still far from optimal.PMID:33982796 | DOI:10.1111/bcp.14899
Source: Clinical Colorectal Cancer - May 13, 2021 Category: Cancer & Oncology Authors: Anat Arbel Zomoroda Abu-Ful Meir Preis Shai Cohen Walid Saliba Source Type: research

Does diet map with mortality? Ecological association of dietary patterns with chronic disease mortality and its spatial dependence in Switzerland
Br J Nutr. 2021 May 11:1-27. doi: 10.1017/S0007114521001525. Online ahead of print.ABSTRACTThe aim of the study was to investigate the associations between dietary patterns and chronic disease mortality in Switzerland using an ecologic design and to explore the spatial dependence of these associations, i.e. the tendency of near locations to present more similar values than randomly expected and distant locations to present more different values. Data of the cross-sectional National Nutrition Survey menuCH (n = 2,057) were used to compute hypothesis- (Alternate Healthy Eating Index, AHEI) and data-driven dietary patterns. D...
Source: The British Journal of Nutrition - May 11, 2021 Category: Nutrition Authors: Giulia Pestoni Nena Karavasiloglou Julia Braun Jean-Philippe Krieger Janice M Sych Matthias Bopp David Faeh Oliver Gruebner Sabine Rohrmann Source Type: research

Cancers, Vol. 13, Pages 2193: Prognosis of Acute Ischaemic Stroke Patients with Cancer: A National Inpatient Sample Study
K Myint Whilst cancer is a risk factor for acute ischaemic stroke (AIS), its impact on AIS prognosis between metastatic and non-metastatic (MC and NMC) disease is poorly understood. Furthermore, the receipt of intravenous thrombolysis (IVT) and endovascular thrombectomy (ET) and their outcomes is poorly researched. AIS admissions from the National Inpatient Sample (NIS) were included (October 2015–December 2017). Multivariable logistic regressions adjusting for a wide range of confounders analysed the relationship between NMC and MC and AIS in-hospital outcomes (mortality, prolonged hospitalisation >4 days...
Source: Cancers - May 3, 2021 Category: Cancer & Oncology Authors: Tiberiu A Pana Mohamed O Mohamed Mamas A Mamas Phyo K Myint Tags: Article Source Type: research

Patient Preferences of Low-Dose Aspirin for Cardiovascular Disease and Colorectal Cancer Prevention in Italy: A Latent Class Analysis
ConclusionPatient preferences for the benefits and risks of low-dose aspirin differ significantly among people eligible for treatment as primary or secondary CVD prevention.
Source: The Patient - Patient-Centered Outcomes Research - April 8, 2021 Category: International Medicine & Public Health Source Type: research

Physical inactivity and non-communicable disease burden in low-income, middle-income and high-income countries
CONCLUSION: The global burden associated with physical inactivity is substantial. The relative burden is greatest in high-income countries; however, the greatest number of people (absolute burden) affected by physical inactivity are living in middle-income countries given the size of their populations.PMID:33782046 | DOI:10.1136/bjsports-2020-103640
Source: British Journal of Sports Medicine - March 30, 2021 Category: Sports Medicine Authors: Peter T Katzmarzyk Christine Friedenreich Eric J Shiroma I-Min Lee Source Type: research

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