Cancers, Vol. 13, Pages 2193: Prognosis of Acute Ischaemic Stroke Patients with Cancer: A National Inpatient Sample Study

Cancers, Vol. 13, Pages 2193: Prognosis of Acute Ischaemic Stroke Patients with Cancer: A National Inpatient Sample Study Cancers doi: 10.3390/cancers13092193 Authors: Tiberiu A Pana Mohamed O Mohamed Mamas A Mamas Phyo K Myint Whilst cancer is a risk factor for acute ischaemic stroke (AIS), its impact on AIS prognosis between metastatic and non-metastatic (MC and NMC) disease is poorly understood. Furthermore, the receipt of intravenous thrombolysis (IVT) and endovascular thrombectomy (ET) and their outcomes is poorly researched. AIS admissions from the National Inpatient Sample (NIS) were included (October 2015–December 2017). Multivariable logistic regressions adjusting for a wide range of confounders analysed the relationship between NMC and MC and AIS in-hospital outcomes (mortality, prolonged hospitalisation >4 days and routine home discharge). Interaction terms with IVT and ET were also computed to explore their impact amongst cancer patients. A total of 221,249 records representative of 1,106,045 admissions were included. There were 38,855 (3.51%) AIS admissions with co-morbid cancer: NMC = 53.78% and MC = 46.22%. NMC was associated with 23% increased odds of in-hospital mortality (odds ratio (95% confidence interval) = 1.23 (1.07–1.42)), which was mainly driven by pancreatic and respiratory cancers. This association was entirely offset by both IVT and ET. MC was associated with two-fold increased odds of in-hospital mortality (2.16 (1.90â...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research