Cancer Will Kill Nearly 10 Million People This Year, Report Estimates

(CNN) — The number of people around the world who have cancer is “rapidly growing,” with 18.1 million new cases and 9.6 million deaths in 2018 alone, researchers estimate in a new report. By the end of the century, cancer will be the No. 1 killer globally and the single biggest barrier to increasing our life expectancy, according to the report, released Wednesday by the World’s Health Organization’s International Agency for Research on Cancer. Cancer by the numbers The researchers used data from 185 countries, looking at all the places in the body cancer can occur and taking a deeper look at 36 types. Based on this data, one in five men and one in six women will develop cancer during their lifetime, the researchers estimate. One in eight men and one in 11 women will die from the disease. The number of cancer cases is increasing for a number of reasons, the report says: The global population is growing, and more people means more cancer. The population is also aging, and cancer risks grow as you age. The numbers also look worse because in many countries, stroke and heart disease deaths are declining. Cancer varies by region The likelihood that you’ll get cancer or die from it depends, in part, on where you live. Nearly half of the new cancer cases and more than half the cancer deaths worldwide were in Asia, home to 60% of the world’s population. The Americas, however, have their own serious problems with the disease, with 21% of cancer...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Cancer Local TV Source Type: news

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Authors: Conte SC, Spagnol G, Biolo M, Confalonieri M Abstract The conventional-trans bronchial needle aspiration (c-TBNA) has been the first procedure for sampling hilar/mediastinal lymph node for the diagnosis/staging of lung cancer. In the last decade the endobronchial ultrasound trans bronchial needle aspiration (EBUS-TBNA) was introduced in clinical practice and became the first-choice exam in diagnosis and staging of lung cancer. The aim of this study was to compare the diagnostic accuracy (DA), sensitivity and adequacy of c-TBNA and EBUS-TBNA. It was a retrospective and observational multicenter study. The f...
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research
Publication date: 18 April 2019Source: Cell, Volume 177, Issue 3Author(s): Ali Torkamani, Eric TopolObesity is one of the most serious health challenges of our time. In this issue of Cell, Khera and co-authors demonstrate the striking ability of genetics, in the form of a polygenic risk score, to identify those individuals at high risk for obesity. This genetic risk expresses itself early as childhood obesity, reinforcing the notion that early prevention is essential to combatting the obesity epidemic.
Source: Cell - Category: Cytology Source Type: research
Publication date: 18 April 2019Source: Cell, Volume 177, Issue 3Author(s): Luca A. Lotta, Jacek Mokrosiński, Edson Mendes de Oliveira, Chen Li, Stephen J. Sharp, Jian’an Luan, Bas Brouwers, Vikram Ayinampudi, Nicholas Bowker, Nicola Kerrison, Vasileios Kaimakis, Diana Hoult, Isobel D. Stewart, Eleanor Wheeler, Felix R. Day, John R.B. Perry, Claudia Langenberg, Nicholas J. Wareham, I. Sadaf FarooqiSummaryThe melanocortin 4 receptor (MC4R) is a G protein-coupled receptor whose disruption causes obesity. We functionally characterized 61 MC4R variants identified in 0.5 million people from UK Biobank and examined their a...
Source: Cell - Category: Cytology Source Type: research
Publication date: 18 April 2019Source: Cell, Volume 177, Issue 3Author(s): Amit V. Khera, Mark Chaffin, Kaitlin H. Wade, Sohail Zahid, Joseph Brancale, Rui Xia, Marina Distefano, Ozlem Senol-Cosar, Mary E. Haas, Alexander Bick, Krishna G. Aragam, Eric S. Lander, George Davey Smith, Heather Mason-Suares, Myriam Fornage, Matthew Lebo, Nicholas J. Timpson, Lee M. Kaplan, Sekar KathiresanSummarySevere obesity is a rapidly growing global health threat. Although often attributed to unhealthy lifestyle choices or environmental factors, obesity is known to be heritable and highly polygenic; the majority of inherited susceptibility...
Source: Cell - Category: Cytology Source Type: research
Publication date: 18 April 2019Source: Cell, Volume 177, Issue 3Author(s): Wantong Yao, Anirban MaitraIn this issue of Cell, Lytle et al. (2019) integrate functional genomic approaches to identify molecular dependencies of pancreatic cancer stem cells that may be exploited therapeutically. The comprehensive analysis reveals an unexpected role for retinoic acid receptor-related orphan receptor gamma (RORγ), a T-cell-associated transcription factor, in defining the stemness and the aggressive behavior of pancreatic cancer.
Source: Cell - Category: Cytology Source Type: research
In conclusion, our results indicated that CEP55 played an important role in promoting the invasion and migration of U251 cell and self-renewal of glioma stem like cells which might be a new therapeutic target for glioma.
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
In this study, we propose a deep convolution neural network for stroke magnetic resonance imaging(MRI) segmentation. The main structure of our network consists of two symmetrical deep sub-networks, in which dense blocks are embedded for extracting effective features from sparse pixels to alleviate the over-fitting problem of deep networks. We use the multi-kernel to divide the network into two sub-networks for acquiring more receptive fields, and the dropout regularization method to achieve an effective feature mapping. For the post-processing of the soft segmentation, we use image median filtering to alleviate noises and ...
Source: Neurocomputing - Category: Neuroscience Source Type: research
Publication date: Available online 18 April 2019Source: NeurocomputingAuthor(s): Pengyi Hao, Kun You, Haozhe Feng, Xinnan Xu, Fan Zhang, Fuli Wu, Peng Zhang, Wei ChenAbstractEarly detection of lung cancer is the most promising path to increase the chance of survival for patients. Accurate lung nodule detection in computed tomography (CT) images is a crucial step in diagnosing lung cancer. CNN based CADe systems diagnose lung nodules in two stages by using one network for detection and another following network for classification or false positive reduction. Besides costly construction, two-stage systems can only find a sin...
Source: Neurocomputing - Category: Neuroscience Source Type: research
In conclusion, G-CSF had beneficial effects after cerebral ischemia on the neurological behavioral outcome, infarct volume and preserved the regular spatial distribution of CA1 hippocampal neurons.
Source: Journal of Chemical Neuroanatomy - Category: Neuroscience Source Type: research
ConclusionsIn postmenopausal obese women, weight loss was associated with an increase in the biochemical parameters of bone resorption. The increase in resorption parameters was related to the magnitude of weight loss.
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
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