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Total 585 results found since Jan 2013.

Association of Coronary Plaque With Low-Density Lipoprotein Cholesterol Levels and Rates of Cardiovascular Disease Events Among Symptomatic Adults
CONCLUSIONS AND RELEVANCE: The findings of this cohort study suggest that in symptomatic patients with severely elevated LDL-C levels of at least 190 mg/dL who are universally considered to be at high risk by guidelines, absence of calcified and noncalcified plaque on coronary computed tomographic angiography was associated with low risk for ASCVD events. These results further suggest that atherosclerosis burden, including CAC, can be used to individualize treatment intensity in patients with severely elevated LDL-C levels.PMID:35147685 | DOI:10.1001/jamanetworkopen.2021.48139
Source: Atherosclerosis - February 11, 2022 Category: Cardiology Authors: Martin B ødtker Mortensen Miguel Ca ínzos-Achirica Flemming Hald Steffensen Hans Erik B øtker Jesper M øller Jensen Niels Peter R ønnow Sand Michael Maeng Jens Meldgaard Bruun Michael J Blaha Henrik Toft S ørensen Manan Pareek Khurram Nasir Bjarne L Source Type: research

Incident peptic ulcers and concomitant treatment of direct oral anticoagulants and oral bisphosphonates —a real-world cohort study
ConclusionBased on our results, concomitant use of oBP and DOAC is associated with a slight increase in the risk of peptic ulcers compared to either drug alone. The prescribing physician should weigh the slight increased risk of ulcer in concomitant users of oBP and DOAC with beneficial reductions in stroke and fractures.
Source: Osteoporosis International - January 26, 2022 Category: Orthopaedics Source Type: research

Stroke self-efficacy questionnaire - Denmark (SSEQ-DK): test-retest of the Danish version
CONCLUSION: The SSEQ-DK showed good test-retest reliability of the single items based on agreement among a population with stroke in the subacute and chronic phase. Broad ICC confidence intervals bar any firm conclusions concerning the test-retest reliability of the activity and self-management scales.TRIAL REGISTRATION: ClinicalTrials.gov NCT03183960. Reg. 15 June 2017.PMID:34994306 | DOI:10.1080/10749357.2021.2016097
Source: Topics in Stroke Rehabilitation - January 7, 2022 Category: Neurology Authors: Sedsel Kristine Stage Pedersen Hanne Pallesen Source Type: research

Trigger team activation in the emergency department at a tertiary university hospital
CONCLUSION Patients with MEP calls are more frequent, have a more diverse aetiology and a higher mortality than patients in the other trigger teams. A need exists for further guidelines and research regarding MEP with a view to reducing the high mortality rate among MEP in the future. FUNDING Annmarie Lassen was funded by an unrestricted grant from the philanthropic fund the Tryg Foundation given to the University of Southern Denmark. TRIAL REGISTRATION The study was approved by the Danish Health Authority (Record no. 3-3013-1385/1) and the Danish Data Protection Agency (Record no. 2013-41-2435).PMID:34983729
Source: Danish Medical Journal - January 5, 2022 Category: General Medicine Authors: Stefan Posth Lonnie Froberg S øren Bak Lisette Okkels Jensen Mikkel Brabrand Annmarie Lassen Source Type: research

Danish validation of the Multimorbidity Treatment Burden Questionnaire (MTBQ) and findings from a population health survey: a mixed-methods study
Conclusion The Danish MTBQ is a valid measure of treatment burden with good construct validity and high internal reliability. This is the first study to explore treatment burden at a population level and provides important evidence to policy makers and clinicians about sociodemographic groups at risk of higher treatment burden.
Source: BMJ Open - January 3, 2022 Category: General Medicine Authors: Pedersen, M. H., Duncan, P., Lasgaard, M., Friis, K., Salisbury, C., Breinholt Larsen, F. Tags: Open access, Research methods Source Type: research

Revascularisation for Symptomatic Peripheral Artery Disease: External Applicability of the VOYAGER PAD Trial
CONCLUSION: Among patients in routine clinical practice, 27.1% were eligible for the VOYAGER PAD trial. These patients were older, had more severe vascular symptoms, higher bleeding risk, and worse prognosis than trial participants.PMID:34924303 | DOI:10.1016/j.ejvs.2021.10.026
Source: PubMed: Eur J Vasc Endovasc ... - December 20, 2021 Category: Surgery Authors: Mette S øgaard Peter B Nielsen Flemming Skj øth Torben B Larsen Nikolaj Eldrup Source Type: research