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Total 585 results found since Jan 2013.

Incretin-based therapy of metabolic disease
Dan Med J. 2022 Dec 21;70(1):A10220597.ABSTRACTRecent studies show that incretin hormone analogues effectively control blood glucose while producing major weight losses and reducing the risk of all-cause mortality, myocardial infarction, stroke and kidney function impairment. Furthermore, the risk of dementia and cognitive impairment is reduced. A monomolecular coagonist (tirzepatide) of receptors for both incretin hormones (glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide) produced HbA1c values below 5.7% in 50% of the treated patients and weight losses exceeding 20% in obese individuals. These new...
Source: Danish Medical Journal - January 11, 2023 Category: General Medicine Authors: Jens Juul Holst Source Type: research

Stroke and myocardial infarction in patients with abdominal aortic aneurysms and new-onset atrial fibrillation
Conclusion Cardiovascular prognosis has improved in patients with prevalent AAA disease and new-onset AF in concordance with optimization of antithrombotic therapy over time. A diagnosis of AF conferred residual risk of stroke and myocardial infarction.PMID:36626930 | DOI:10.1055/a-2009-8954
Source: Thrombosis and Haemostasis - January 10, 2023 Category: Hematology Authors: Chalotte Winther Winther Nicolajsen Peter Br ønnum Nielsen Martin Jensen Nikolaj Eldrup Torben Bjerregaard Larsen Gregory Yh Lip Samuel Z Goldhaber Mette S øgaard Source Type: research

Agreement between self-reported diseases from health surveys and national health registry data: a Danish nationwide study
Conclusion Overall, self-reported data were accurate in identifying individuals without the specific disease (ie, specificity and NPV). However, sensitivity, PPV and kappa varied greatly between diseases. These findings should be considered when interpreting similar results from surveys.
Source: Journal of Epidemiology and Community Health - January 10, 2023 Category: Epidemiology Authors: Jensen, H. A. R., Lau, C. J., Davidsen, M., Ekholm, O., Christensen, A. I. Tags: Original research Source Type: research

Low-Density Lipoprotein Cholesterol Is Predominantly Associated With Atherosclerotic Cardiovascular Disease Events in Patients With Evidence of Coronary Atherosclerosis: The Western Denmark Heart Registry
CONCLUSIONS: LDL-C appears to be almost exclusively associated with ASCVD events over ≈5 years of follow-up in middle-aged individuals with versus without evidence of coronary atherosclerosis. This information is valuable for individualized risk assessment among middle-aged people with or without coronary atherosclerosis.PMID:36621817 | DOI:10.1161/CIRCULATIONAHA.122.061010
Source: Circulation - January 9, 2023 Category: Cardiology Authors: Martin B ødtker Mortensen Omar Dzaye Hans Erik B øtker Jesper M øller Jensen Michael Maeng Jacob Fog Bentzen Helle Kanstrup Henrik Toft S ørensen Jonathon Leipsic Ron Blankstein Khurram Nasir Michael J Blaha Bjarne Linde N ørgaard Source Type: research