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Condition: Thrombosis
Procedure: Ultrasound

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Total 256 results found since Jan 2013.

Bedside Ultrasound Diagnosis of Acute Embolic Femoral Artery Occlusion
Abstract: Background: Acute limb ischemia is both a limb-threatening and life-threatening disease process. Nontraumatic acute peripheral arterial occlusion is most commonly caused by a thrombosis or an embolism.Objectives: There is limited evidence on the use of bedside ultrasound for the detection of acute limb ischemia, but duplex ultrasonography is standard in the diagnosis and operative planning in chronic limb ischemia. Emergency physicians may use bedside ultrasound in the evaluation of patients with symptoms and signs suggestive of this disease entity.Case Report: A 64-year-old man with a past medical history of hy...
Source: The Journal of Emergency Medicine - August 28, 2013 Category: Emergency Medicine Authors: Daniel M. Rolston, Turandot Saul, Tommy Wong, Resa E. Lewiss Tags: Ultrasound in Emergency Medicine Source Type: research

Carotid endarterectomy for symptomatic low-grade carotid stenosis
Conclusions: This study shows that CEA is a safe, effective, and durable treatment for patients with symptomatic low-grade carotid stenosis associated with unstable plaque. Patients had excellent protection against further ischemic events and survived long enough to justify the initial surgical risk. Plaque instability seems to play a major part in the onset of ischemic events, regardless the entity of lumen narrowing.
Source: Journal of Vascular Surgery - August 19, 2013 Category: Surgery Authors: Enzo Ballotta, Annalisa Angelini, Franco Mazzalai, Giacomo Piatto, Antonio Toniato, Claudio Baracchini Tags: Clinical research studies Source Type: research

Increased platelet activation in early symptomatic vs. asymptomatic carotid stenosis and relationship with microembolic status: results from the Platelets and Carotid Stenosis Study
DiscussionRecently, symptomatic carotid stenosis patients have had higher platelet counts (potentially reflecting increased platelet production, mobilization or reduced clearance) and platelet activation status than asymptomatic patients. MES were more frequently detected in early symptomatic than asymptomatic patients, but the differences between late symptomatic and asymptomatic groups were not significant. Increased lymphocyte‐platelet complex formation in recently symptomatic vs. asymptomatic MES‐negative patients indicates enhanced platelet activation in this early symptomatic subgroup. Platelet biomarkers, in com...
Source: Journal of Thrombosis and Haemostasis - July 15, 2013 Category: Hematology Authors: J. A. Kinsella, W. O. Tobin, S. Tierney, T. M. Feeley, B. Egan, D. R. Collins, T. Coughlan, D. O'Neill, J. Harbison, P. Madhavan, D. J. Moore, S. M. O'Neill, M. P. Colgan, C. P. Doherty, R. P. Murphy, M. Saqqur, N. Moran, G. Hamilton, D. J. H McCabe Tags: Original Article Source Type: research

MRI artifacts in the ferric chloride thrombus animal model: an alternative solution
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - June 29, 2013 Category: Hematology Authors: Martijn Wolters, Raf H.M. Hoof, A. Wagenaar, Kim Douma, Marc A.M.J. Zandvoort, Tilman H. Hackeng, Mark J. Post, Walter H. Backes, M. Eline Kooi Tags: Letter ‐ to the Editor Source Type: research

Is Sonothrombolysis an Effective Stroke Treatment?
New therapeutic strategies under development aim to improve recanalization rates and clinical outcomes after ischemic stroke. One such approach is ultrasound (US)-enhanced thrombolysis, or sonothrombolysis, which can improve thrombolytic drug actions and even intrinsic fibrinolysis. Although the mechanisms are not fully understood, it is postulated that thrombolysis enhancement is related to nonthermal mechanical effects of US. Recent results indicate that US with or without microbubbles may be effective in clot lysis of ischemic stroke even without additional thrombolytic drugs. Sonothrombolysis is a promising tool for tr...
Source: Journal of Ultrasound in Medicine - June 26, 2013 Category: Radiology Authors: Mijajlovic, M. D., Pavlovic, A. M., Covickovic-Sternic, N. Tags: Review Article Source Type: research

157 E-Books New to JEFFLINE
Scott Library added these 157 e-books to the growing collection in May and June: Accurate Results in the Clinical Laboratory Adult Emergency Medicine Adult-Gerontology and Family Nurse Practitioner Certification Examination (4th ed.) Advanced Assessment: Interpreting Findings and Formulating Differential Diagnoses (2nd ed.) Advancing Your Career: Concepts of Professional Nursing (5th ed.) Arrhythmia Essentials Atlas of Advanced Operative Surgery Atlas of Clinical Neurology (3rd ed.) Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches Atlas of Human Infectious Diseases Atlas of No...
Source: What's New on JEFFLINE - June 25, 2013 Category: Databases & Libraries Authors: Gary Kaplan Tags: All News Clinicians Researchers Students Teaching Faculty Source Type: news

Unexpected Arterial Recanalization after Decompressive Hemicraniectomy
We report a 43-year-old patient with malignant embolic ischemic stroke in the right middle cerebral artery (MCA), treated by decompressive hemicraniectomy. Cerebrovascular ultrasound detected a subtotally occluding thrombus in the right internal carotid artery and a partial occlusion of the ipsilateral MCA. After the surgery, complete recanalization of the affected vessels was observed.
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: Evguenia Vassileva, Petar Stoyanov, Evgenii Vavrek, Paraskeva Stamenova Tags: Case Reports Source Type: research

Closing the Loop: A 21-year Audit of Strategies for Preventing Stroke and Death Following Carotid Endarterectomy
The objective of this review was to identify causes of stroke/death after carotid endarterectomy (CEA) and to develop transferable strategies for preventing stroke/death after CEA, via an overview of a 21-year series of themed research and audit projects. Three preventive strategies were identified: (i) intra-operative transcranial Doppler (TCD) ultrasound and completion angioscopy which virtually abolished intra-operative stroke, primarily through the removal of residual luminal thrombus prior to restoration of flow; (ii) dual antiplatelet therapy with a single 75-mg dose of clopidogrel the night before surgery in additio...
Source: European Journal of Vascular and Endovascular Surgery - June 17, 2013 Category: Surgery Authors: A.R. Naylor, R.D. Sayers, M.J. McCarthy, M.J. Bown, A. Nasim, M.J. Dennis, N.J.M. London, P.R.F. Bell Tags: Carotid Disease Source Type: research

Closing the Loop: A 21-year Audit of Strategies for Preventing Stroke and Death Following Carotid Endarterectomy.
The objective of this review was to identify causes of stroke/death after carotid endarterectomy (CEA) and to develop transferable strategies for preventing stroke/death after CEA, via an overview of a 21-year series of themed research and audit projects. Three preventive strategies were identified: (i) intra-operative transcranial Doppler (TCD) ultrasound and completion angioscopy which virtually abolished intra-operative stroke, primarily through the removal of residual luminal thrombus prior to restoration of flow; (ii) dual antiplatelet therapy with a single 75-mg dose of clopidogrel the night before surgery in additio...
Source: PubMed: Eur J Vasc Endovasc ... - June 13, 2013 Category: Surgery Authors: Naylor AR, Sayers RD, McCarthy MJ, Bown MJ, Nasim A, Dennis MJ, London NJ, Bell PR Tags: Eur J Vasc Endovasc Surg Source Type: research

Review Non-pharmacological strategies for the treatment of acute ischaemic stroke
Early recanalisation and an increase in collateral blood supply are predictors of favourable outcome in acute ischaemic stroke. Since individual responses to intravenous treatment with alteplase are heterogeneous, additional intra-arterial thrombolytic and mechanical endovascular treatment is increasingly given. Despite encouraging findings from single-centre studies, data from randomised clinical trials have not proven the hypothesis that interventional recanalisation leads to a better outcome. Advanced thrombectomy devices, the effect of ultrasound-enhanced thrombolysis, and imaging-guided selection of patients outside t...
Source: Lancet Neurology - May 24, 2013 Category: Neurology Authors: Michael G Hennerici, Rolf Kern, Kristina Szabo Tags: Review Source Type: research

CLOTBUST-Hands Free: Initial Safety Testing of a Novel Operator-Independent Ultrasound Device in Stroke-Free Volunteers Clinical Sciences
Conclusions— Our novel device was well tolerated by stroke-free volunteers and did not cause any neurological dysfunction nor did it affect blood brain barrier integrity. The safety and efficacy of the device are now being tested in stroke patients receiving intravenous tissue-type plasminogen activator in phase II–III clinical trials.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Barlinn, K., Barreto, A. D., Sisson, A., Liebeskind, D. S., Schafer, M. E., Alleman, J., Zhao, L., Shen, L., Cava, L. F., Rahbar, M. H., Grotta, J. C., Alexandrov, A. V. Tags: Other Treatment, Acute Cerebral Infarction, Doppler ultrasound, Transcranial Doppler etc. Clinical Sciences Source Type: research

Carotid Artery Free-Floating Thrombus Caused by Paradoxical Embolization From Greater Saphenous Vein Ascending Thrombophlebitis
We report a case of a young woman without cardiovascular risk factors who was admitted to our emergency department with listlessness and altered mental status. The clinical examination revealed right lower limb swelling. Magnetic resonance imaging and contrast-enhanced computed tomographic scans revealed a free floating thrombus of the left internal carotid artery (ICA) with a large bilateral frontal ischemic lesion. The diagnosis of a medium-sized PFO with moderate right-to-left contrast shunting was made after transesophageal echocardiography. No other cardiac sources for embolization were detected, while an ascending th...
Source: Annals of Vascular Surgery - April 28, 2013 Category: Surgery Authors: Luigi Irace, Roberto Gabrielli, Maria Sofia Rosati, Maria Fabrizia Giannoni, Anna Castiglione, Antonella Laurito, Bruno Gossetti Tags: Case Report Abstracts Source Type: research

Increased platelet activation in early symptomatic versus asymptomatic carotid stenosis and relationship with microembolic status: Results from the Platelets And Carotid Stenosis (PACS) Study
This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - April 26, 2013 Category: Hematology Authors: JA Kinsella, WO Tobin, S Tierney, TM Feeley, B Egan, DR Collins, T Coughlan, D O'Neill, J Harbison, P Madhavan, DJ Moore, SM O'Neill, MP Colgan, CP Doherty, RP Murphy, M Saqqur, N Moran, G Hamilton, DJH McCabe Tags: Original Article ‐ Platelets Source Type: research

"Fou Rire Prodromique" as the Presentation of a Left Frontal Ischemic Stroke (P02.040)
CONCLUSIONS: Frontal lobe involvement affecting the Broca's area, as we described in our case, has only been described once. We conclude that the patient's laughter attack was the initial manifestation of the stroke suggesting that an acute infarct of Broca's area is capable of producing this unusual clinical presentation.Disclosure: Dr. Rosales has nothing to disclose. Dr. Garcia-Gracia has nothing to disclose. Dr. Salgado has received personal compensation in an editorial capacity from Belvoir Media Group as Consulting Editor of A Special Report published by the editors of Heart Advisor Cleveland Clinic STROKE: Advances ...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Rosales, D., Garcia-Gracia, C., Salgado, E. Tags: P02 Cerebrovascular Disease II Source Type: research

Knowledge of vascular status for therapeutic decision-making in acute ischemic stroke: which is the role of neurosonology?.
Abstract In the last years there is an increasing interest in the knowledge of vascular status in patients with acute stroke. Detection and localization of an artery occlusion is of great interest for an accurate prognosis and the selection of the most appropriate recanalizing therapy. Neurosonology is a useful diagnostic tool for vascular status study in patients with acute stroke. Different situations where ultrasounds offer a valuable diagnostic information are reviewed, such as middle cerebral artery (MCA) occlusion, 'T' internal carotid artery (ICA) occlusion, 'tandem' ICA-MCA occlusion, monitoring of intra-c...
Source: Revista de Neurologia - January 1, 2013 Category: Neurology Authors: Garcia-Pastor A Tags: Rev Neurol Source Type: research