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Condition: Rheumatoid Arthritis

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Total 493 results found since Jan 2013.

Rheumatoid arthritis significantly increased recurrence risk after ischemic stroke/transient ischemic attack
This study provides the first evidence that RA significantly increased recurrence IS/TIA risk. The changes of TG/HDL-C ratio may play some roles in the recurrence IS/TIA risk in RA patients. In addition, our results suggest that smoking increases the risk of recurrent IS/TIA in RA patients and reinforces the need for aggressive smoking cessation efforts in RA patients.
Source: Journal of Neurology - June 2, 2018 Category: Neurology Source Type: research

Increased Incidence of Stroke and Transient Ischemic Attack in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis in Germany
Conclusion: RA was significantly associated with stroke and TIA, with young patients being at a particularly increased risk. AS was tendentially associated with stroke and TIA.Neuroepidemiology
Source: Neuroepidemiology - March 31, 2021 Category: Epidemiology Source Type: research

Stroke among Rheumatoid Arthritis Patients: Does Age Matter A Real-Life Study
Conclusion: RA is independently associated with stroke, especially among RA patients under 65 years, for whom cardiovascular risk factors were more prominent. Physicians should advise RA patients to manage their risk factors strictly.Neuroepidemiology 2017;49:99 –105
Source: Neuroepidemiology - November 14, 2017 Category: Epidemiology Source Type: research

Exploring metabolic and inflammatory abnormalities in rheumatoid arthritis patients developing stroke disease: a case-control study using electronic medical record data in northern China
ConclusionsA close monitoring is required for RA patients with dyslipidemia and elevated inflammatory markers, and the primary stroke preventive strategies should be directed against these risk factors.
Source: Clinical Rheumatology - February 7, 2019 Category: Rheumatology Source Type: research

Interleukin-17 and ischemic stroke.
Abstract Interleukin-17 (IL-17) is a cytokine family that includes 6 members, IL-17A through IL-17F, most of them are reported to have pro-inflammatory role. Through binding to their receptors (IL-17Rs), IL-17 activates the intracellular signaling pathways to play an important role in autoimmune diseases, including rheumatoid arthritis (RA) and multiple sclerosis (MS). Ischemic stroke is a complex pathophysiological process mainly caused by regional cerebral ischemia. Inflammatory factors contribute to the physiological process of stroke that leads to poor prognosis. IL-17 plays a crucial role in promoting inflamm...
Source: Immunology - September 15, 2020 Category: Allergy & Immunology Authors: Zhang Q, Liao Y, Liu Z, Dai Y, Li Y, Li Y, Tang Y Tags: Immunology Source Type: research

Methotrexate might reduce ischemic stroke in patients with rheumatoid arthritis: a population ‐based retrospective cohort study
ConclusionsAt a dosage of > 0.5 defined daily dose, short‐term methotrexate might decrease ischemic stroke risk in RA patients, while hydroxychloroquine and sulfasalazine were neutral.
Source: APLAR Journal of Rheumatology - January 1, 2018 Category: Rheumatology Authors: Hong ‐Wei Tam, Chyong‐Mei Chen, Pui‐Ying Leong, Chao‐Hsi Chen, Yuan‐Chao Li, Yu‐Hsun Wang, Li‐Chi Lin, Jeng‐Yuan Chiou, James Cheng‐Chung Wei Tags: Original Article Source Type: research

Rheumatoid meningitis: A rare cause of aseptic meningitis with frequently stroke-like episodes
Conclusions RM is a rare manifestation of RA and often presents with stroke-like episodes. It is currently not implemented in the workup of aseptic meningitis in national guidelines. Crucial clues for diagnosis included recurrent stroke-like episodes refractory to antiepileptic treatment, headache and constitutional symptoms, meningeal enhancement on MRI, CSF pleocytosis, and positive serology findings for ACPA and RF. Prognosis is favorable with early immunosuppressive treatment.
Source: Neurology Clinical Practice - October 15, 2018 Category: Neurology Authors: Schuster, S., Braass, H., Iking-Konert, C., Schnoor, U., Matschke, J., Gerloff, C., Thomalla, G., Magnus, T. Tags: Autoimmune diseases, Meningitis, All Clinical Neurology Review Source Type: research

Genetic Variants of the NLRP3 Inflammasome Are Associated with Stroke in Patients with Rheumatoid Arthritis.
CONCLUSION: Genetic variants of the NLRP3 inflammasome influence the risk of stroke/TIA, but not of MI/angina pectoris in Swedish patients with established RA. PMID: 26178285 [PubMed - as supplied by publisher]
Source: J Rheumatol - July 15, 2015 Category: Rheumatology Authors: Kastbom A, Ärlestig L, Rantapää-Dahlqvist S Tags: J Rheumatol Source Type: research

Potential benefits of biologics on stroke and mortality in patients with rheumatoid arthritis: A nationwide population ‐based cohort study in Taiwan
ConclusionBiologics used in RA patients have been shown to have a beneficial impact on improving clinical outcomes, including decreased risks of death and stroke. The economic burden from costs of biologics may be alleviated by improving outcomes.
Source: International Journal of Rheumatic Diseases - June 24, 2019 Category: Rheumatology Authors: Chao ‐Hsiun Tang, Fun Yu, Ching‐Ya Huang, Der‐Yuan Chen Tags: ORIGINAL ARTICLE Source Type: research

Association between ischemic stroke and seropositive rheumatoid arthritis in Korea: A nationwide longitudinal cohort study
by Dong Hyun Lee, Seung Hun Sheen, Dong-Geun Lee, Jae-Won Jang, Dong Chan Lee, Seung-Ho Shin, In-bo Han, Je Beom Hong, Hakyung Kim, Seil Sohn The purpose of this longitudinal follow-up study was to investigate the risk of ischemic stroke nationwide in patients with seropositive rheumatoid arthritis (RA) and controls who were matched in age and sex. Patient data were collected from the National Health Insurance Service (NHIS) Health Scre ening (HEALS) cohort. Using the International Classification of Diseases code M05 (seropositive RA), with a prescription of any disease-modifying anti-rheumatic drug (DMARD), RA was identi...
Source: PLoS One - May 17, 2021 Category: Biomedical Science Authors: Dong Hyun Lee Source Type: research

Rheumatoid Arthritis Patients Have Better Outcomes Than Non-Rheumatoid Arthritis Patients When Hospitalized for Ischemic Stroke: Analysis of the National Inpatient Sample
Objectives The aims of this study were to compare the outcomes of patients primarily admitted for ischemic stroke with and without a secondary diagnosis of RA. Methods Data were abstracted from the National Inpatient Sample (NIS) 2016 and 2017 database. The NIS was searched for hospitalizations for adult patients with ischemic stroke as principal diagnosis with and without RA as secondary diagnosis using International Classification of Diseases, 10th Revision codes. The primary outcome was inpatient mortality. Hospital length of stay (LOS), total hospital charges, odds of receiving tissue plasminogen activator, ...
Source: JCR: Journal of Clinical Rheumatology - December 31, 2021 Category: Rheumatology Tags: Original Articles Source Type: research

Preliminary Investigation: Acupoint-Skin Conductance in Stroke Survivors.
Abstract It has been reported that patients with rheumatoid arthritis or asthma have skin conductance over the acupoints that is lower than that of their healthy counterparts; this has been regarded as indirect evidence of the existence of acupoints and the energy-based model of diseases. In order to investigate the potential application of acupoint-skin conductance measurement that may reflect pathology of ischemic stroke, the present study recruited 34 stroke survivors with hemiparesis, whose skin conductance of a hand acupoint and an adjacent non-acupoint and the finger temperature in both affected and unaffect...
Source: Applied Psychophysiology and Biofeedback - June 6, 2014 Category: Psychiatry & Psychology Authors: Wong YM Tags: Appl Psychophysiol Biofeedback Source Type: research

Risk of ischemic stroke in patients with polymyositis and dermatomyositis: a systematic review and meta-analysis
Abstract Several chronic inflammatory disorders, such as rheumatoid arthritis and systemic lupus erythematosus, have been demonstrated to increase ischemic stroke risk, but the data on polymyositis (PM) and dermatomyositis (DM) remain unclear. We conducted a systematic review and meta-analysis of observational studies that reported odds ratio, relative risk, hazard ratio or standardized incidence ratio comparing ischemic risk in patients with PM/DM versus non-PM/DM participants. Pooled risk ratio and 95 % confidence intervals were calculated using a random-effect, generic inverse variance method of DerSimonian a...
Source: Rheumatology International - April 23, 2015 Category: Rheumatology Source Type: research

Risk of hemorrhagic transformation after ischemic stroke in patients with antiphospholipid antibody syndrome.
CONCLUSION: APS is an independent risk factor for hemorrhagic transformation in both thrombolytic and non-thrombolytic treated patients. APS is also associated with longer length and cost of hospital stay. Further research is warranted to identify the unique risk factors in these patients to identify strategies to reduce the risk of hemorrhagic transformation in this subgroup of the population. PMID: 28475479 [PubMed - as supplied by publisher]
Source: Neurological Research - May 8, 2017 Category: Neurology Tags: Neurol Res Source Type: research

Cross-diagnostic scale-banking using Rasch analysis: Developing a common reference metric for generic and health condition-specific scales in people with rheumatoid arthritis and stroke.
CONCLUSION: This study provides a transformation table to enable direct comparisons among instruments measuring physical functioning commonly used in rheumatoid arthritis (HAQ) and stroke (FIMTM motor scale), as well as in people with disability in general (WHODAS 2.0). PMID: 32909047 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - September 12, 2020 Category: Rehabilitation Tags: J Rehabil Med Source Type: research