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Condition: Rheumatoid Arthritis
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Total 493 results found since Jan 2013.
Acupuncture for ischemic stroke, music for anxiety in mechanical ventilation, essential fatty acids for depression, mindfulness meditation for sleep in older adults, Tripterygium wilfordii for rheumatoid arthritis
Publication date: Available online 30 October 2015 Source:EXPLORE: The Journal of Science and Healing Author(s): Richard Glickman-Simon, Justin Steurich
Source: EXPLORE: The Journal of Science and Healing - October 31, 2015 Category: Complementary Medicine Source Type: research
Diagnostic Magnetic Resonance Imaging of Atherosclerosis in Apolipoprotein E Knockout Mouse Model Using Macrophage-Targeted Gadolinium-Containing Synthetic Lipopeptide Nanoparticles
by Zu T. Shen, Shaokuan Zheng, Matthew J. Gounis, Alexander B. Sigalov
Cardiovascular disease is the leading cause of death in Western cultures. The vast majority of cardiovascular events, including stroke and myocardial infarction, result from the rupture of vulnerable atherosclerotic plaques, which are characterized by high and active macrophage content. Current imaging modalities including magnetic resonance imaging (MRI) aim to characterize anatomic and structural features of plaques rather than their content. Previously, we reported that macrophage-targeted delivery of gadolinium (Gd)-based contrast agent (GBCA-HDL) ...
Source: PLoS One - November 16, 2015 Category: Biomedical Science Authors: Zu T. Shen et al. Source Type: research
Correlates of a Single-Item Quality-of-Life Measure in People Aging with Disabilities
Objective: Practical quality-of-life (QOL) screening methods are needed to help focus clinical decision-making on what matters to individuals with disabilities.
Design: A secondary analysis of a database from a large study of adults aging with impairments focused on four diagnostic groups: cerebral palsy (n = 134), polio (n = 321), rheumatoid arthritis (n = 99), and stroke (n = 82). Approximately 20% of cases were repeated measures of the same individuals 3–5 yrs later. Functional levels, depression, and social interactions were assessed. The single-item, subjective, seven-point Kemp Quality of Life Scale measured QOL. F...
Source: American Journal of Physical Medicine and Rehabilitation - November 22, 2015 Category: Rehabilitation Tags: Original Research Articles Source Type: research
Causes of changes in carotid intima-media thickness: a literature review
Atherosclerosis causes significant morbidity and mortality. Carotid intima-media thickness (CIMT) predicts future cardiovascular and ischaemic stroke incidence. CIMT, a measure of atherosclerotic disease, can be reliably determined in vivo by carotid ultrasound. In this review, we determined that CIMT is associated with traditional cardiovascular risk factors such as age, sex, race, smoking, alcohol consumption, habitual endurance exercise, blood pressure, dyslipidemia, dietary patterns, risk-lowering drug therapy, glycemia, hyperuricemia, obesity-related anthropometric parameters, obesity and obesity-related diseases. We ...
Source: Cardiovascular Ultrasound - December 15, 2015 Category: Radiology Authors: Baoge QuTao Qu Source Type: research
Duplex Ultrasonography-Detected Positional Vertebral Artery Occlusion in Upper Cervical Rheumatoid Arthritis
Study Design. Prospective imaging study.
Objective. To clarify the frequency of positional vertebral artery (VA) occlusion using duplex ultrasonography in patients with rheumatoid arthritis (RA).
Summary of Background Data. Some patients with upper cervical RA develop thromboembolic stroke related to positional and transient VA occlusions; however, whether RA patients have positional VA occlusion without neurological symptoms is unclear.
Methods. Outpatients with RA were enrolled. Clinical data were collected, and radiograph examinations were performed to measure the anterior atlantodental interval (AADI), the posterior at...
Source: Spine - December 21, 2015 Category: Orthopaedics Tags: Cervical Spine Source Type: research
The impact of inflammatory rheumatic diseases on the presentation, severity, and outcome of acute coronary syndrome
Abstract
Patients with inflammatory rheumatic diseases (IRD) have a high burden of cardiovascular disease (CVD), leading to increased mortality and morbidity. However, it is not clear whether increased CVD mortality in IRD is due to a higher incidence or worse outcome of cardiovascular events (higher case fatality). In this observational case–control study, we assessed the outcome of acute coronary syndrome (ACS) in patients with IRDs compared to matched controls without IRD, using data from the Acute Coronary Syndrome Israeli Survey (ACSIS), a large, national, real-life registry detailing the extent, severity,...
Source: Clinical Rheumatology - January 1, 2016 Category: Rheumatology Source Type: research
Cardiovascular Comorbidities Relate More than Others with Disease Activity in Rheumatoid Arthritis
Conclusions Cardiovascular comorbidities relate more than others with disease activity in RA. Diabetes and hyperlipidemia in particular seem associated with higher and lower disease activity respectively influencing almost all considered outcomes, suggesting a special importance of this pattern of comorbidities in disease activity assessment and clinical management.
Source: PLoS One - January 12, 2016 Category: Biomedical Science Authors: Gloria Crepaldi et al. Source Type: research
Thalidomide Analogs that Inhibit Inflammation and Angiogenesis
Thalidomide and its close analogs (lenalidomide and pomalidomide) are widely used to treat a variety of diseases, such as multiple myeloma and other cancers as well as the symptoms of several inflammatory disorders. However, thalidomide is known for its teratogenic adverse effects when first clinically introduced in the 1950s, and is associated with drowsiness and peripheral neuropathy. Hence, there is intense interest to synthesize, identify and develop safer analogs.Researchers at the National Institute on Aging’s Drug Design and Development Section synthesized novel thalidomide analogs that demonstrate clinical potent...
Source: NIH OTT Licensing Opportunities - December 23, 2015 Category: Research Authors: admin Source Type: research
Primary Sjögren's syndrome presenting with multiple aneurysmal dilatation of cerebral arteries and causing repetitive intracranial hemorrhage
Sjögren's syndrome (SS) is characterized by mononuclear infiltration and destruction of salivary and lachrymal glands leading to xerostomia and xerophthalmia [1]. This syndrome is classified as primary SS in the absence of other autoimmune diseases, and as secondary SS when it is associated with other autoimmune diseases such as rheumatoid arthritis, scleroderma, and systemic lupus erythematosus. The incidence of stroke among patients with SS is 2% and SS is even more rarely complicated with cerebral artery lesions [2].
Source: Journal of the Neurological Sciences - April 18, 2016 Category: Neurology Authors: Teppei Komatsu, Hidetaka Mitsumura, Ichiro Yuki, Yasuyuki Iguchi Tags: Letter to the Editor Source Type: research
Multifactorial intervention to prevent cardiovascular disease in patients with early rheumatoid arthritis: protocol for a multicentre randomised controlled trial
In this study, we compare the effect of a targeted, intensified, multifactorial intervention with that of conventional treatment of modifiable risk factors for cardiovascular disease (CVD) in patients with early RA fulfilling the 2010 American College of Rheumatology European League Against Rheumatism (ACR/EULAR) criteria.
Methods and analysis
The study is a prospective, randomised, open label trial with blinded end point assessment and balanced randomisation (1:1) conducted in 10 outpatient clinics in Denmark. The primary end point after 5 years of follow-up is a composite of death from cardiovascular causes, non-fa...
Source: BMJ Open - April 19, 2016 Category: Journals (General) Authors: Svensson, A. L., Christensen, R., Persson, F., Logstrup, B. B., Giraldi, A., Graugaard, C., Fredberg, U., Blegvad, J., Thygesen, T., Hansen, I. M. J., Colic, A., Bagdat, D., Ahlquist, P., Jensen, H. S., Horslev-Petersen, K., Sheetal, E., Christensen, T. G Tags: Open access, Cardiovascular medicine, Rheumatology Protocol Source Type: research
The association of hypertension with asymptomatic cardiovascular organ damage in rheumatoid arthritis.
CONCLUSION: The presence of asymptomatic cardiovascular organ damage in RA patients is closely associated with hypertension independent of inflammatory activity.
PMID: 27123584 [PubMed - as supplied by publisher]
Source: Blood Pressure - April 30, 2016 Category: Hematology Tags: Blood Press Source Type: research
Hypoxia-responsive nanocarriers for cancer imaging and therapy: Recent approaches and future perspectives
Chem. Commun., 2016, Accepted ManuscriptDOI: 10.1039/C6CC02972H, Feature ArticleThavasyappan Thambi, Jae Hyung Park, Doo Sung LeeHypoxia, a condition in which tissue is deprived of adequate oxygen supply, is a salient feature of various intractable diseases, including rheumatoid arthritis, ischemic stroke, and solid tumors. In particular,...The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - May 13, 2016 Category: Chemistry Authors: Thavasyappan Thambi Source Type: research
Vitamin D Deficiency Is As Dangerous As Smoking
The advice you’re getting from your doctor, the TV and even the Surgeon General is so wrong, it’s scary.
They’re all busy telling you to stay out of the sun.
But Swedish researchers recently discovered that nonsmokers who avoid the sun have a life expectancy similar to smokers who spend a lot of time in the sun.
Staying out of the sun is as dangerous as smoking.1
It doesn’t surprise me. I tell all my patients sunlight exposure is essential to our health because it is the best source of vitamin D… possibly the most important nutrient we know of.
Mainstream medicine still doesn’t recognize th...
Source: Al Sears, MD Natural Remedies - May 19, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Health Source Type: news
Turmeric: Bali’s Anti-Cancer Tonic
I’m always happy to find things in my travels to bring back to you. Today I want to tell you about a miracle of nature called turmeric.
Turmeric has been used to treat a wide variety of conditions.
You can read about it in-depth in my latest book, Healing Herbs of Paradise.
The roots of this exotic leafy plant contain curcumin, a very powerful antioxidant that also has remarkable anti-inflammatory properties.1,2,3
What Does Curcumin Do?
Curcumin neutralizes free radicals… those nasty little chemicals that travel through your body and cause damage to healthy cells and cell membranes.
Which means curcumin effectivel...
Source: Al Sears, MD Natural Remedies - May 25, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Cancer Source Type: news
PT251 Strain Analysis by Speckle-Tracking Echocardiography in a Rheumatoid Arthritis Hispanic Cohort
The leading cause of death in rheumatoid arthritis (RA) is atherosclerotic cardiovascular disease (ASCVD), predominantly acute myocardial infarction, stroke and congestive heart failure. Myocardial strain analysis by speckle-tracking echocardiography is a useful tool for the early detection of heart failure with preserved ejection fraction. Data regarding right and left ventricular strain in RA is limited.
Source: CVD Prevention and Control - May 27, 2016 Category: Cardiology Authors: F. Hervert-Cavazos, J.R. Azpiri-Lopez, A. Ordaz-Farias, R.P. Vera-Pineda, A. Martinez-Moreno, J.A. Cardenas-de la Garza, M.A. Benavides-Gonzalez, I.J. Colunga-Pedraza, M.A. Garza-Elizondo, D.A. Galarza-Delgado Tags: Poster Abstract Source Type: research
