African Rigorous Innovative Stroke Epidemiological Surveillance: Protocol for a Community-Based Mobile-Health Study
Despite projections of stroke being a leading cause of mortality in Africa, reliable estimates of stroke burden on the continent using rigorous methods are not available. We aimed to implement a mobile-Health community-based interactive Stroke Information and Surveillance System to sustainably measure stroke burden and improve stroke health literacy and outcomes in urban and rural sites in Nigeria. African Rigorous Innovative Stroke Epidemiological Surveillance (ARISES) is an observational cohort study, which will be conducted in urban (Ibadan North LGA Ward 3) and rural (Ibarapa Central LGA) sites with a combined base pop...
Source: Neuroepidemiology - November 25, 2021 Category: Epidemiology Source Type: research

Traumatic Brain Injury and Risk of Dementia and Alzheimer ’s Disease: A Systematic Review and Meta-Analysis
Conclusion: Our study suggests an increased risk of dementia among individuals with TBI, highlighting the need for more intensive medical monitorin g and health education in individuals with TBI. Biological mechanisms linking TBI and the development of dementia are needed in future studies. (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 24, 2021 Category: Epidemiology Source Type: research

Epidemiology of Primary Brain Tumors in the Province of Catania during the 2003 –2016 Period
Conclusions: The IR of PBTs in the province of Catania is close to incidence reported worldwide. Further studies on risk factors are necessary.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 18, 2021 Category: Epidemiology Source Type: research

Secular Trends in the Incidence, Prevalence, and Medications for Epilepsy from 2007 to 2015 in Taiwan: A Nationwide Population-Based Study
Conclusions: The overall prevalence and incidence of epilepsy decreased slightly from 2007 to 2015. The prescribed first-line anticonvulsant also changed over time.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 15, 2021 Category: Epidemiology Source Type: research

A Comparison of Epidemiological Characteristics of Central Nervous System Tumours in China and Globally from 1990 to 2019
Conclusions: The burden of CNSTs is very serious in China, and we should pay attention to the key populations, early diagnosis technology, improvements in medical technology, and ways to reduce medical costs. We believe our results could help policymakers allocate resources efficiently to reduce the burden of CNSTs.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 15, 2021 Category: Epidemiology Source Type: research

Creutzfeldt - Jakob Disease in South West Sydney 2014-2020: An Unusually High Incidence of a Rare Disease
Conclusions The incidence of CJD, in SWSLHD, exceeds the national average of 1/million. Cost-effective, adequate diagnostic and screening tools, implementab le over a large population, will become increasingly essential.   (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 11, 2021 Category: Epidemiology Source Type: research

Prevalence of Parkinson ’s disease in China: a multicenter population-based survey
Conclusion:The prevalence of Parkinson's disease in individuals aged 65 and older in China has not increased significantly in recent years. The prevalence of Parkinson's disease is higher in men than in women and higher in urban areas than in rural areas. (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 10, 2021 Category: Epidemiology Source Type: research

Treatment with Multiple Therapeutic Classes of Medication is Associated with Survival after Stroke
Conclusion: Treatment with all three classes of guideline-recommended medications within 90 days post-discharge was associated with better survival. Ongoing efforts are required to ensure optimal pharmacological intervention for secondary prevention of stroke. (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 10, 2021 Category: Epidemiology Source Type: research

Identification of prodromal presentations of Parkinson ’s disease among primary care outpatients in Germany
This study aimed to identify clinical features that predate the diagnosis of PD in a primary care setting. Methods: This retrospective case-control study was based on data from the Disease Analyzer database (IQVIA) and included 17,702 patients with Parkinson ’s disease and 17,702 non-PD controls matched for age, sex, and index year. We analyzed the prevalence of 15 defined diagnoses and symptoms documented within 2 years, ≥2 to (Source: Neuroepidemiology)
Source: Neuroepidemiology - November 1, 2021 Category: Epidemiology Source Type: research

Diabetes As an Independent Risk Factor for Stroke Recurrence in Ischemic Stroke Patients: An Updated Meta-Analysis
Conclusion: Diabetes is an independent risk factor for stroke recurrence among patients with IS.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 21, 2021 Category: Epidemiology Source Type: research

Disability-Adjusted Life Years and Mortality Rate Attributed to Brain and Central Nervous System Cancer in the Middle East and North Africa Countries
Conclusion: The incidence rate, prevalence, and standardized age mortality (per 100,000) had increased significantly in the MENA region in 2019 compared to those in 1990. Focusing on the diversity of the estimates of such indices in different countries of MENA can lead to the identification of important risk factors for brain cancer in future studies.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 14, 2021 Category: Epidemiology Source Type: research

Brain Health, One Health, and COVID-19
Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - October 11, 2021 Category: Epidemiology Source Type: research

Contents Vol. 50, 2018
Neuroepidemiology 2018;50:I –IV (Source: Neuroepidemiology)
Source: Neuroepidemiology - September 22, 2021 Category: Epidemiology Source Type: research

The Effectiveness of Stroke Riskometer ™ in Improving Stroke Risk Awareness in Malaysia: A Study Protocol of a Cluster-Randomized Controlled Trial
Conclusion: This study will evaluate the effect of Stroke Riskometer™ app on stroke awareness and stroke probability and briefly evaluate participant engagement to a pre-specified trial protocol. The findings from this will inform physicians and public health professionals of the benefit of mobile technology intervention and encourage more active mobile phone-based disease prevention apps.Trial Registration: ClinicalTrials.gov Identifier NCT04529681.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - September 15, 2021 Category: Epidemiology Source Type: research

Data from 235 Cases of Bell ’s Palsy during COVID-19 Pandemic: Were There Clusters of Facial Palsy?
Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - September 8, 2021 Category: Epidemiology Source Type: research

Association of Hypertension with Mild Cognitive Impairment in Population from Less-Developed Areas of Multiethnic Northwest China
Conclusion: Hypertension is in independent negative association with MCI in middle-aged and elderly population from underdeveloped regions.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - August 25, 2021 Category: Epidemiology Source Type: research

Comparing Vascular Brain Injury and Stroke by Cranial Magnetic Resonance Imaging, Physician-Adjudication, and Self-Report: Data from the Strong Heart Study
Conclusion: In this community-based cohort, self-report for prior stroke had good performance metrics. A majority of participants with VBI did not have overt, clinically recognized events but did have neurological or cognitive symptoms. Data collection methodology for studies in a resource-limited setting must balance practical limitations in costs, accuracy, feasibility, and research goals.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - August 24, 2021 Category: Epidemiology Source Type: research

Epidemiology of Parkinson ’s Disease in Chile
Conclusion: The prevalence and incidence observed in the Chilean population are consistent with studies from other countries.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - August 18, 2021 Category: Epidemiology Source Type: research

Pediatric Acute Ischemic Stroke by Age-Group: A Systematic Review and Meta-Analysis of Published Studies and Hospitalization Records
Conclusions: Incidence rates of pediatric AIS by age-groups followed a consistent overall pattern of a reverse J-shaped curve, with the highest rates in neonates, across predominantly European and North American countries. Further research is warranted to examine if this pattern is observed in other geographic regions and to identify AIS risk factors specific to different phases of childhood development.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - August 17, 2021 Category: Epidemiology Source Type: research

Epidemiology of Epilepsy in Low- and Middle-Income Countries: Experience of a Standardized Questionnaire over the Past Two Decades
Conclusion: Over the last 2 decades, the IENT questionnaire has been continuously used in different LMICs. This result favors its promotion and updating, with the inclusion of new topics related to epilepsy (e.g., comorbidities, quality of life, and stigma), current ILAE guidelines, and digital versions.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - July 27, 2021 Category: Epidemiology Source Type: research

Predicting the Risk of Ischemic Stroke in Patients Treated with Novel Oral Anticoagulants: A Machine Learning Approach
Conclusions: The stroke risk in AF patients treated with NOAC could be predicted based on comorbidities like ischemic heart diseases, urinary tract infections, and dementia additionally to age and male sex. Knowing and addressing these factors may help reduce the risk of stroke in this patient population.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - July 21, 2021 Category: Epidemiology Source Type: research

Modeling Manifest Huntington ’s Disease Prevalence Using Diagnosed Incidence and Survival Time
Conclusion: The modeled estimates generally accord with the previously published data. This analysis contributes to better understanding of the epidemiology of HD and highlights areas of uncertainty.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - July 15, 2021 Category: Epidemiology Source Type: research

Estimated Prevalence and Incidence of Amyotrophic Lateral Sclerosis and SOD1 and C9orf72 Genetic Variants
Discussion: The estimated number of patients with SOD1 and C9orf72 ALS suggests that although the proportions of SOD1 and C9orf72 are higher among those with fALS, the majority of SOD1 and C9orf72 ALS cases may be found among those with sALS (about 53 and 74%, respectively). These results suggest that classification of fALS based on reported family history does not capture the full picture of ALS of genetic origin.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - July 9, 2021 Category: Epidemiology Source Type: research

Reduction in Acute Stroke Admissions during the COVID-19 Pandemic: Data from a National Stroke Registry
Conclusion: The marked decrease in admissions for acute stroke and TIA, occurring at a time of a relatively low burden of COVID-19, is of great concern. Public awareness campaigns are needed as patients reluctant to seek urgent stroke care are deprived of lifesaving procedures and secondary prevention treatments.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - July 8, 2021 Category: Epidemiology Source Type: research

Reproductive History and Age of Onset for Women Diagnosed with Amyotrophic Lateral Sclerosis: Data from the National ALS Registry: 2010 –2018
Conclusion: Women who reported completing menopause before age 50 were significantly more likely to be diagnosed with ALS before age 60 compared with those who reported entering menopause after age 50. More research is needed to determine the relationship between female reproductive history, especially regarding endogenous estrogen exposure and early-onset ALS.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - July 2, 2021 Category: Epidemiology Source Type: research

Characteristics Associated with Olfactory and Taste Disorders in COVID-19
Conclusion: This study confirms the higher frequency of OTDs in females than males and adults than children. Their high predictive value for the diagnosis of COVID-19 suggests that they should be systematically searched for in patients with respiratory symptoms, fever, or headache. The association of OTDs with headache, not previously reported, suggests that they share a common mechanism, which deserves further investigation.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - July 1, 2021 Category: Epidemiology Source Type: research

The Burden of Dementia due to Down Syndrome, Parkinson ’s Disease, Stroke, and Traumatic Brain Injury: A Systematic Analysis for the Global Burden of Disease Study 2019
Background: In light of the increasing trend in the global number of individuals affected by dementia and the lack of any available disease-modifying therapies, it is necessary to fully understand and quantify the global burden of dementia. This work aimed to estimate the proportion of dementia due to Down syndrome, Parkinson ’s disease, clinical stroke, and traumatic brain injury (TBI), globally and by world region, in order to better understand the contribution of clinical diseases to dementia prevalence.Methods: Through literature review, we obtained data on the relative risk of dementia with each condition and es...
Source: Neuroepidemiology - June 28, 2021 Category: Epidemiology Source Type: research

Characteristics, Management, and Case-Fatality of Patients Hospitalized for Stroke with a Diagnosis of COVID-19 in France
Conclusion: Patients hospitalized for stroke with a concomitant COVID-19 diagnosis had a higher inhospital and 3 months case-fatality rates compared to patients hospitalized for stroke without a COVID-19 diagnosis. Further research is needed to better understand the excess of mortality related to these cases.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - June 24, 2021 Category: Epidemiology Source Type: research

Current and Future Projections of Amyotrophic Lateral Sclerosis in the United States Using Administrative Claims Data
Conclusions: This study provides incidence and prevalence estimates as well as geographical distribution for what the authors believe to be the largest ALS population studied to date. By using 2 separate administrative claims data sets, confidence in our estimates is increased. Future projections based on either database demonstrate an increase in ALS cases, which has also been seen in other large-scale ALS studies. These results can be used to help improve the allocation of healthcare resources in the future.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - June 21, 2021 Category: Epidemiology Source Type: research

Cerebral Small-Vessel Disease in Individuals with a Family History of Coronary Heart Disease: The Atherosclerosis Risk in Communities Study
Conclusion: Markers of cSVD, specifically lacunar infarcts and microhemorrhages, appear to be associated with FHCHD, potentially representing shared mechanisms in different vascular beds, and perhaps a genetic propensity for vascular disease.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - June 17, 2021 Category: Epidemiology Source Type: research

Alcohol Consumption and Stroke Risk in Men: A Population-Based Cohort Study in Rural Tianjin, China
Conclusions: These findings suggest that low-dose alcohol consumption may decrease the risk of ischemic strokes among men. Even so, the adverse effects of alcohol on the liver and pancreas cannot be ignored. Additionally, the effects of alcohol consumption on stroke risk vary with age, protecting against ischemic and total strokes among males ≥55 years old. Nevertheless, recommending light drinking and its potential health benefits should not be generalized to men of all ages.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - June 15, 2021 Category: Epidemiology Source Type: research

Association between Circulating Protein C Levels and Incident Dementia: The Atherosclerosis Risk in Communities Study
Conclusion: Circulating protein C has an inverse association with incident dementia independent of established risk factors, including stroke. Our results suggest studying anticoagulants in addition to coagulants can increase our understanding on the relationship between hemostasis and dementia.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - June 2, 2021 Category: Epidemiology Source Type: research

Putting Fine Particulate Matter and Dementia in the Wider Context of Noncommunicable Disease: Where are We Now and What Should We Do Next: A Systematic Review
Conclusion: The evidence base for PM2.5 as a risk factor for dementia is growing. It is not yet as strong as that for other NCDs. However, varied measurement/methodology hampers clarity across the field. We propose next steps.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - June 1, 2021 Category: Epidemiology Source Type: research

Temporal Trends in the Incidence of Ischemic Stroke in Young Adults: Dijon Stroke Registry
Conclusions: The incidence of ischemic stroke in young adults increased during the early 2000s and remained stable thereafter. These results highlight the priority need for dedicated prevention strategies for the young to reduce the burden of stroke.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - May 27, 2021 Category: Epidemiology Source Type: research

Stroke and Heart Attack Symptom Recognition in Older US Adults by Cognitive Impairment Status
Conclusions: Additional work is needed to address the challenge of improving recognition levels for specific stroke and heart attack symptoms in older US adults with cognitive impairment and especially for members of this group who live alone.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - May 19, 2021 Category: Epidemiology Source Type: research

The Association between Substance Use Disorders and Long-Term Outcome of Stroke: Results from a Population-Based Study of Stroke among 450,229 Urban Citizens
Conclusion: SUD increased the hazard ratio of stroke mortality with no effect on the disability rate. The public should be advised about the potential harm of substance abuse.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - May 11, 2021 Category: Epidemiology Source Type: research

Antibiotic Use and Risk of Multiple Sclerosis: A Nested Case-Control Study in Emilia-Romagna Region, Italy
Conclusions: Our results suggest an association between the use of antibiotics and MS risk in RER population. However, further epidemiological studies should be done with information on early life and lifestyle factors.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - May 7, 2021 Category: Epidemiology Source Type: research

Prevalence of Medically Resistant Epilepsy in Saudi Arabia
Conclusion: The prevalence of MRE in our population (30%) is close to that in other populations (30 –36.5%). Early identification of such patients is crucial to improve their management.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - May 6, 2021 Category: Epidemiology Source Type: research

Epidemiology of Parkinson ’s Disease in Rural Gujarat, India
Conclusions: The present study showed the current epidemiological data of PD from Gujarat, in western India. Further studies across different regions in India need to be encouraged for better understanding of PD prevalence in the Indian population.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - May 5, 2021 Category: Epidemiology Source Type: research

Rural Stroke Surveillance and Establishment of Acute Stroke Care Pathway Using Frontline Health Workers in Rural Northwest India: The Ludhiana Experience
Conclusion: ASHAs were able to identify stroke patients in the villages. Despite high numbers of patients reaching health-care facilities within a window period, the hospitals were unable to provide acute stroke treatment like thrombolysis. The health-care system needs to be strengthened to improve stroke care.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - May 5, 2021 Category: Epidemiology Source Type: research

Renal Impairment and Risk of Acute Stroke: The INTERSTROKE Study
Conclusion: Renal impairment is an important risk factor for stroke, particularly in younger patients, and is associated with more severe stroke and worse outcomes.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - May 5, 2021 Category: Epidemiology Source Type: research

The Incidence of Amyotrophic Lateral Sclerosis in Ohio 2016 –2018: The Ohio Population-Based ALS Registry
Conclusion: The estimated Ohio incidence of ALS is overall similar to that reported in other states in the USA. This study reveals a geospatial variation in incidence within the state, and areas with higher rates warrant future investigation.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - April 26, 2021 Category: Epidemiology Source Type: research

High-Risk Periods for Adult Traumatic Brain Injuries: A Nationwide Population-Based Study
Conclusions: TBI-related hospital admissions and mortality were more common on public holidays, weekends, and in summer months in Finland. People who sustained TBIs on these days were on average younger and healthier. The occurrence of TBIs on public holidays and weekends is increasing at an alarming rate.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - April 14, 2021 Category: Epidemiology Source Type: research

Cause of Death after Traumatic Brain Injury: A Population-Based Health Record Review Analysis Referenced for Nonhead Trauma
Conclusion: This population-based case-matched referent study showed that increased risk of death after TBI existed only during the first 6 months after injury, and the difference was due to external causes.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - April 9, 2021 Category: Epidemiology Source Type: research

Risk Factors for Olfactory and Gustatory Dysfunctions in Patients with SARS-CoV-2 Infection
Conclusion: Our study indicates that current smoking and history of allergy (particularly respiratory) significantly increase the risk for smell loss in COVID-19 patients; the latter is also significantly associated to taste loss. Hospitalization has an inverse association with the risk of olfactory and gustatory dysfunctions, suggesting that these may be symptoms characteristics of less severe SARS-CoV-2 infection.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - April 1, 2021 Category: Epidemiology Source Type: research

Increased Incidence of Stroke and Transient Ischemic Attack in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis in Germany
Conclusion: RA was significantly associated with stroke and TIA, with young patients being at a particularly increased risk. AS was tendentially associated with stroke and TIA.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - March 31, 2021 Category: Epidemiology Source Type: research

Development of the Madrid Stroke Programme: Milestones and Changes in Stroke Trends and Mortality from 1997 to 2017
Conclusions: Our study illustrates how measures such as the development of stroke units, implementation of a regional stroke code and treatment with intravenous thrombolysis coincide in time with a reduction in in-hospital mortality due to stroke.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - March 30, 2021 Category: Epidemiology Source Type: research

Morbidity, Mortality, and Conversion to Neurodegenerative Diseases in Patients with REM Sleep Behavior Disorder and REM Sleep without Atonia
Conclusions: A diagnosis of RBD is associated with increased morbidity several years before and after a diagnosis is made. Patients have a higher risk of converting to a neurodegenerative disorder than matched controls. Mortality rates are unchanged.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - March 29, 2021 Category: Epidemiology Source Type: research

The Prevalence of Mild Cognitive Impairment among Chinese People: A Meta-Analysis
Conclusions: The prevalence of MCI in China was 15.4%, which varied by demographics, lifestyles, morbidity, screening tools, and diagnostic criteria. In further studies, screening tools and diagnosis criteria should be considered when estimating MCI prevalence.Neuroepidemiology (Source: Neuroepidemiology)
Source: Neuroepidemiology - March 23, 2021 Category: Epidemiology Source Type: research

7th International Conference on Neurology and Epidemiology
Neuroepidemiology 2021;55(suppl 1):I –II (Source: Neuroepidemiology)
Source: Neuroepidemiology - March 16, 2021 Category: Epidemiology Source Type: research