Filtered By:
Condition: Hypothermia

This page shows you your search results in order of relevance. This is page number 7.

Order by Relevance | Date

Total 450 results found since Jan 2013.

Stroke Due to Air Embolism Related to Laser Ablation of Accessory Vein (P4.357)
Conclusions: Air embolism leading to devastating stroke may occur few hours after laser treatment of varicose veins. Chest symptoms associated with the procedure should raise the possibility of air embolism. Immediate therapeutic measures like 100[percnt] oxygen, hyperbaric oxygen chamber and/or hypothermia should be considered to prevent neurologic complications.Disclosure: Dr. Kale has nothing to disclose. Dr. Javed has nothing to disclose. Dr. Pednekar has nothing to disclose. Dr. Sahni has nothing to disclose. Dr. Resor has nothing to disclose. Dr. Tenner has nothing to disclose. Dr. Ahluwalia-Singh has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kale, P., Javed, B., Pednekar, N., Sahni, R., Resor, L., Tenner, M., Ahluwalia-Singh, B. Tags: Cerebrovascular Case Reports Source Type: research

TFP5 is comparable to mild hypothermia in improving neurological outcomes in early-stage ischemic stroke of adult rats
Conclusions: TFP5 is comparable to MH in improving neurological outcomes in early-stage adult ischemic stroke. When TFP5 is given along with MH, less neurological deficit tends to be achieved.
Source: Neuroscience - January 1, 2017 Category: Neuroscience Source Type: research

Dihydrocapsaicin (DHC) Enhances the Hypothermia-Induced Neuroprotection Following Ischemic Stroke Via PI3K/Akt Regulation In Rat.
CONCLUSIONS: The combination approach is able to enhance the efficiency of hypothermia and efficacy of hypothermia-induced neuroprotection following ischemic stroke. The findings here move us a step closer towards translating this long recognized TH from bench to bedside. PMID: 28684048 [PubMed - as supplied by publisher]
Source: Brain Research - July 3, 2017 Category: Neurology Authors: Wu D, Shi J, Elmadhoun O, Duan Y, An H, Zhang J, He X, Meng R, Liu X, Ji X, Ding Y Tags: Brain Res Source Type: research

Statistical analysis plan for the EuroHYP-1 trial: European multicentre, randomised, phase III clinical trial of the therapeutic hypothermia plus best medical treatment versus best medical treatment alone for acute ischaemic stroke
Cooling may reduce infarct size and improve neurological outcomes in patients with ischaemic stroke. In phase II trials, cooling awake patients with ischaemic stroke has been shown to be feasible and safe, but...
Source: Trials - November 29, 2017 Category: General Medicine Authors: Per Winkel, Philip M. Bath, Christian Gluud, Jane Lindschou, H. Bart van der Worp, Malcolm R. Macleod, Istvan Szabo, Isabelle Durand-Zaleski and Stefan Schwab Tags: Update Source Type: research

Combined local hypothermia and recanalization therapy for acute ischemic stroke: Estimation of brain and systemic temperature using an energetic numerical model
Publication date: Available online 4 July 2019Source: Journal of Thermal BiologyAuthor(s): Yannick Lutz, Axel Loewe, Stephan Meckel, Olaf Dössel, Giorgio CattaneoAbstractLocal brain hypothermia is an attractive method for providing cerebral neuroprotection for ischemic stroke patients and at the same time reducing systemic side effects of cooling. In acute ischemic stroke patients with large vessel occlusion, combination with endovascular mechanical recanalization treatment could potentially allow for an alleviation of inflammatory and apoptotic pathways in the critical phase of reperfusion. The direct cooling of arterial...
Source: Journal of Thermal Biology - July 6, 2019 Category: Biology Source Type: research

Commentary: Stroke after type A aortic dissection repair —A web of risk with no single answer
In this issue of the Journal, Ghoreishi and colleagues1 have performed a tour de force in attempting to analyze 5 major factors potentially associated with stroke after type A aortic dissection repair. The etiology of stroke after aortic surgery is an entanglement of numerous complex factors that place patients at risk for both ischemic and embolic neurologic insults. Decisions about the extent of surgical repair, cannulation site, cerebral perfusion strategy, and degree of hypothermia are all interrelated.
Source: The Journal of Thoracic and Cardiovascular Surgery - June 19, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Robert B. Hawkins, J. Hunter Mehaffey, John A. Kern Tags: Commentary Source Type: research

Intra-arterial neuroprotective therapy as an adjunct to endovascular intervention in acute ischemic stroke: A review of the literature and future directions.
Authors: Link TW, Santillan A, Patsalides A Abstract Mechanical thrombectomy for acute ischemic stroke due to large vessel occlusion has been shown to significantly improve outcomes. However, despite efficient rates of recanalization (60-90%), the rates of functional independence remain suboptimal (14-58%), most likely due to pathways of cell death in the brain that have already committed despite successful reperfusion. Pharmacologic neuroprotection provides a potential means of preventing this inevitable damage through targeting excitotoxicity, reactive oxygen species, cellular apoptosis, and inflammation. Numerou...
Source: Interventional Neuroradiology - May 21, 2020 Category: Radiology Tags: Interv Neuroradiol Source Type: research

The Future of Therapeutic Hypothermia for Stroke The Future of Therapeutic Hypothermia for Stroke
Renewed interest and recent data suggest that hypothermia may be neuroprotective in patients suffering from stroke.Medscape Neurology
Source: Medscape Neurology and Neurosurgery Headlines - May 22, 2020 Category: Neurology Tags: Neurology & Neurosurgery Expert Column Source Type: news

Selective Brain Hypothermia in Acute Ischemic Stroke: Reperfusion Without Reperfusion Injury
In acute ischemic stroke, early recanalization of the occluded artery is crucial for best outcome to be achieved. Recanalization aims at restoring blood flow to the ischemic tissue (reperfusion) and is achieved with pharmacological thrombolytic drugs, endovascular thrombectomy (EVT) devices, or both. The introduction of modern endovascular devices has led to tremendous anatomical and clinical success with rates of substantial reperfusion exceeding 80% and proven clinical benefit in patients with anterior circulation large vessel occlusions (LVOs). However, not every successful reperfusion procedure leads to the desired cli...
Source: Frontiers in Neurology - November 13, 2020 Category: Neurology Source Type: research

Phenothiazine Inhibits Neuroinflammation and Inflammasome Activation Independent of Hypothermia After Ischemic Stroke
In conclusion, C + P treatment conferred neuroprotection in stroke by suppressing neuroinflammation and NLRP3 inflammasome activation. The present study suggests that JAK2/STAT3/p38/HIF-1α/FoxO1 are vital regulators and potential targets for efficacious therapy following ischemic stroke.
Source: Molecular Neurobiology - August 29, 2021 Category: Neurology Source Type: research

Ultra-Short Duration Hypothermia Prevents Intracranial Pressure Elevation Following Ischaemic Stroke in Rats
There is a transient increase in intracranial pressure (ICP) 18–24 h after ischaemic stroke in rats, which is prevented by short-duration hypothermia using rapid cooling methods. Clinical trials of long-duration hypothermia have been limited by feasibility and associated complications, which may be avoided by short-duration cooling. Animal studies have cooled faster than is achievable in patients. We aimed to determine whether gradual cooling at a rate of 2°C/h to 33°C or 1°C/h to 34.5°C, with a 30 min duration at target temperatures, prevented ICP elevation and reduced infarct volume in rats. Transient middle cerebr...
Source: Frontiers in Neurology - September 20, 2021 Category: Neurology Source Type: research

The intra-arterial selective cooling infusion system: A  mathematical temperature analysis and in vitro experiments for acute ischemic stroke therapy
CONCLUSION: This prototype instrument system could safely cool simulated blood in vitro and reperfuse it to the target cerebral blood vessel. This technique could promote the clinical application of an autologous blood perfusion system for stroke therapy.PMID:35702957 | DOI:10.1111/cns.13883
Source: CNS Neuroscience and Therapeutics - June 15, 2022 Category: Neuroscience Authors: Miaowen Jiang Ming Li Yuan Gao Longfei Wu Wenbo Zhao Chuanhui Li Chengbei Hou Zhengfei Qi Kun Wang Shiqiang Zheng Zhichen Yin Chuanjie Wu Xunming Ji Source Type: research

Amino acid solution mitigates hypothermia response and intestinal damage following exertional heat stroke in male mice
Exertional heat stroke (EHS) is a debilitating and potentially fatal condition for which few prevention strategies exist. These results suggest that a 5AAS improves Tc regulation during EHS recovery through maintaining mucosal function and integrity and that protecting the GI tract during EHS may be beneficial in some of the health consequences of EHS exposure. AbstractIncreased gut permeability is implicated in the initiation and extent of the cytokine inflammatory response associated with exertional heat stroke (EHS). The primary objective of this study was to determine if a five amino acid oral rehydration solution (5AA...
Source: Physiological Reports - May 23, 2023 Category: Physiology Authors: Michelle A. King, Astrid Grosche, Shauna M. Ward, Jermaine A. Ward, Anusree Sasidharan, Thomas A. Mayer, Mark L. Plamper, Xiaodong Xu, Matthew D. Ward, Thomas L. Clanton, Sadasivan Vidyasagar Tags: ORIGINAL ARTICLE Source Type: research