Filtered By:
Cancer: Brain Cancers

This page shows you your search results in order of relevance. This is page number 10.

Order by Relevance | Date

Total 2156 results found since Jan 2013.

Medicinal plants against ischemic stroke.
Abstract Ischemic stroke is one of the major causes of global deaths. Prominent changes in the Central Nervous System (CNS) are observable including emotional, cognitive and behavioural changes during the recovery phase of a stroke. Brain ischemia affects a large portion of patients across the world with permanent disability or death. During the ischemic stroke onset, apart from inducing brain damage, existing microglial cells, immune cells, inflammatory factors such as chemokines and cytokines affect the process of brain repair. For the reduction of this damage, there is a need of understanding the basic mechanis...
Source: Current Pharmaceutical Biotechnology - December 9, 2020 Category: Biotechnology Authors: Roy A, Datta S Tags: Curr Pharm Biotechnol Source Type: research

Preclinical Evidence and Possible Mechanisms of Rhodiola rosea L. and Its Components for Ischemic Stroke: A Systematic Review and Meta-Analysis
Conclusion: The findings suggested that RRC can improve ischemia stroke. The possible mechanisms of RRC are largely through antioxidant, anti-apoptosis activities, anti-inflammatory, repressing lipid peroxidation, antigliosis, and alleviating the pathological blood brain barrier damage.
Source: Frontiers in Pharmacology - November 5, 2021 Category: Drugs & Pharmacology Source Type: research

Risk factors and predictors for venous thromboembolism in people with ischemic stroke: A systematic review
In conclusion, this systematic review informs on several potential risk factors and predictors for VTE in people with ischemic stroke. To improve risk stratification and guide development of risk prediction models, further confirmation is needed, as there were few high-quality studies on each factor.PMID:35815351 | DOI:10.1111/jth.15813
Source: Thrombosis and Haemostasis - July 11, 2022 Category: Hematology Authors: Birgitte G T øndel V ânia M Morelli John-Bjarne Hansen Sigrid K Braekkan Source Type: research

Candesartan Reduces the Hemorrhage Associated with Delayed Tissue Plasminogen Activator Treatment in Rat Embolic Stroke.
Abstract We have previously reported that angiotensin receptor blockade reduces reperfusion hemorrhage in a suture occlusion model of stroke, despite increasing matrix metalloproteinase (MMP-9) activity. We hypothesized that candesartan will also decrease hemorrhage associated with delayed (6 h) tissue plasminogen activator (tPA) administration after embolic stroke, widening the therapeutic time window of tPA. Adult male Wistar rats were subjected to embolic middle cerebral artery occlusion (eMCAO) and treated with either candesartan (1 mg/kg) alone early at 3 h, delayed tPA (10 mg/kg) alone at 6 h, the combi...
Source: Neurochemical Research - November 6, 2013 Category: Neuroscience Authors: Ishrat T, Pillai B, Ergul A, Hafez S, Fagan SC Tags: Neurochem Res Source Type: research

Transplantation of human dental pulp-derived stem cells protects against heat stroke in mice.
In conclusion, post-WBH treatment with SHED reduced induction of pro-inflammatory cytokines and oxidative radicals, enhanced plasma induction of both adrenocorticotrophic hormone and corticosterone, and improved lethality in mice heat stroke. The protective effect of SHED may be related to a decreased inflammatory response, a decreased oxidative stress, and an increased hypothalamo-pituitaryadrenocortical axis activity following the WBH injury. PMID: 24612725 [PubMed - as supplied by publisher]
Source: Cell Transplantation - March 7, 2014 Category: Cytology Authors: Tseng LS, Chen SH, Lin MT, Lin YC Tags: Cell Transplant Source Type: research

A Case of Perioperative Stroke Caused by Tumour Embolus. (P6.244)
CONCLUSIONS: Tumour embolism has previously been described with primary and secondary lung neoplasms, as well as cardiac tumours. Although rare, this should be considered as a potential cause of perioperative stroke in patients after cancer surgery.Study Supported by: Non-applicable.Disclosure: Dr. Hughes has nothing to disclose. Dr. Hunter has nothing to disclose. Dr. Campbell has nothing to disclose. Dr. Brady has nothing to disclose. Dr. Herron has nothing to disclose. Dr. Smyth has nothing to disclose. Dr. Rennie has nothing to disclose. Dr. Hunt has received personal compensation for activities with Eisai Inc., UCB Ph...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Hughes, S., Hunter, A., Campbell, J., Brady, A., Herron, B., Smyth, G., Rennie, I., Hunt, S. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Safety of intravenous thrombolysis for acute ischaemic stroke including concomitant neoplastic disease sufferers – experience from Poland
ConclusionIntravenous thrombolysis performed in Caucasian stroke patients with past or current neoplastic diseases, but not in the course of chemo‐ and radiotherapy, can be a safe and effective method of treatment. In making decision on the thrombolytic treatment, the risk of bleeding complications and the life expectancy should be assessed.
Source: International Journal of Clinical Practice - February 27, 2015 Category: Internal Medicine Authors: P. Sobolewski, W. Brola, W. Szczuchniak, M. Fudala, A. Sobota Tags: Original Paper Source Type: research

E-051 acute ischemic stroke due to tumorigenic embolism treated with mechanical thrombectomy
ConclusionIn acute stroke secondary to malignant tumorigenic embolism, mechanical thrombectomy might be a safe and effective treatment option.DisclosuresB. Bell: None. A. Saad: None. K. Layton: None. S. Shamim: None. G. Snipes: None. K. Hesselrode: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Bell, B., Saad, A., Layton, K., Shamim, S., Snipes, G., Hesselrode, K. Tags: SNIS 12th Annual Meeting Electronic Poster Abstracts Source Type: research

Transplantation of unique subpopulation of fibroblasts, Muse cells, ameliorates experimental stroke possibly via robust neuronal differentiation
This article is protected by copyright. All rights reserved.
Source: Stem Cells - September 21, 2015 Category: Stem Cells Authors: Hiroki Uchida, Takahiro Morita, Kuniyasu Niizuma, Yoshihiro Kushida, Yasumasa Kuroda, Shohei Wakao, Hiroyuki Sakata, Yoshiya Matsuzaka, Hajime Mushiake, Teiji Tominaga, Cesario V. Borlongan, Mari Dezawa Tags: Regenerative Medicine Source Type: research

Role of serum‐ and glucocorticoid‐inducible kinases in stroke
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - April 27, 2016 Category: Neuroscience Authors: Koichi Inoue, Tiandong Leng, Tao Yang, Zhao Zeng, Takatoshi Ueki, Zhi‐Gang Xiong Tags: Original Article Source Type: research

An efficient automated methodology for detecting and segmenting the ischemic stroke in brain MRI images
Abstract Brain tumor and brain stroke are two important causes of death in and around the world. The abnormalities in brain cell leads to brain stroke and obstruction in blood flow to brain cells leads to brain stroke. In this article, a computer aided automatic methodology is proposed to detect and segment ischemic stroke in brain MRI images using Adaptive Neuro Fuzzy Inference (ANFIS) classifier. The proposed method consists of preprocessing, feature extraction and classification. The brain image is enhanced using Heuristic histogram equalization technique. Then, texture and morphological features are extracted from the ...
Source: International Journal of Imaging Systems and Technology - August 17, 2017 Category: Radiology Authors: P. Sivakumar, P. Ganeshkumar Tags: RESEARCH ARTICLE Source Type: research

Inhibition of miR-141-3p Ameliorates the Negative Effects of Poststroke Social Isolation in Aged Mice Basic Sciences
Conclusions—miR-141-3p is increased with poststroke isolation. Inhibition of miR-141-3p improved mortality, neurological deficits, and decreased infarct volumes. Importantly, these therapeutic effects occurred in aged animals, the population most at risk for stroke and poststroke isolation.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Rajkumar Verma, Rodney M. Ritzel, Nia M. Harris, Juneyoung Lee, TaeHee Kim, Gopal Pandi, Raghu Vemuganti, Louise D. McCullough Tags: Basic Science Research, Ischemia, Translational Studies Original Contributions Source Type: research

Stroke-Like Presentation of Paraneoplastic Cerebellar Degeneration: a Single-Center Experience and Review of the Literature.
We report herein incidence and clinical features of hyperacute onset PCD, a vertebrobasilar stroke mimic. We performed a retrospective analysis of all suspected PCD cases referred to the Udine University Hospital between 2009 and 2017. Our center provides the only neuroimmunology laboratory for three provinces of the Friuli-Venezia Giulia region, Italy (983,190 people as of January 1, 2017). Inclusion criteria were (1) abrupt onset of neurological symptoms; (2) initial consideration of a vascular etiology; (3) final diagnosis of "definite PCD." We also carried out a systematic review of the literature in order to identify ...
Source: Cerebellum - August 28, 2019 Category: Neuroscience Authors: Vogrig A, Bernardini A, Gigli GL, Corazza E, Marini A, Segatti S, Fabris M, Honnorat J, Valente M Tags: Cerebellum Source Type: research

Calycosin Preserves BDNF/TrkB Signaling and Reduces Post-Stroke Neurological Injury after Cerebral Ischemia by Reducing Accumulation of Hypertrophic and TNF- α-Containing Microglia in Rats
This study was a prospective, randomized, blinded and placebo-controlled preclinical experiment. Sprague-Dawley adult rats, subjected to transient focal cerebral ischemia by middle cerebral artery occlusion (MCAO), were treated randomly with 0 (corn oil and/or saline as placebo), 30  mg/kg of Calycosin and/or 1 mg/kg of a tropomyosin-related kinase B (TrkB) receptor antagonist (ANA12) at 1 h after reperfusion and once daily for a total of 7 consecutive days. BDNF and its functional receptor, full-length TrkB (TrkB-FL) levels, the percentage of hypertrophic microglia, tumor n ecrosis factor-α (TNF-α)-containing microgl...
Source: Journal of NeuroImmune Pharmacology - January 10, 2020 Category: Drugs & Pharmacology Source Type: research