Inhibition of miR-141-3p Ameliorates the Negative Effects of Poststroke Social Isolation in Aged Mice [Basic Sciences]
Conclusions—miR-141-3p is increased with poststroke isolation. Inhibition of miR-141-3p improved mortality, neurological deficits, and decreased infarct volumes. Importantly, these therapeutic effects occurred in aged animals, the population most at risk for stroke and poststroke isolation.
Source: Stroke - Category: Neurology Authors: Rajkumar Verma, Rodney M. Ritzel, Nia M. Harris, Juneyoung Lee, TaeHee Kim, Gopal Pandi, Raghu Vemuganti, Louise D. McCullough Tags: Basic Science Research, Ischemia, Translational Studies Original Contributions Source Type: research
More News: Brain | Brain Cancers | Genetics | Insulin | Neurology | Neuroscience | Neurosurgery | Science | Stroke | Study