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Total 393 results found since Jan 2013.

Enhancing recombinant protein and viral vector production in mammalian cells by targeting the YTHDF readers of N6-methyladenosine in mRNA
This article is protected by copyright. All rights reserved.PMID:36692010 | DOI:10.1002/biot.202200451
Source: Biotechnology Journal - January 24, 2023 Category: Biotechnology Authors: Nga Lao Niall Barron Source Type: research

Analysis of polymeric nanoparticle properties for siRNA/DNA delivery in a tumor xenograft tissue slice air-liquid interface model
CONCLUSION: The ex vivo 3D tissue slice ALI culture model is a powerful system that allows the effective evaluation of biological nanoparticle efficacy and biocompatibility in an intact tissue environment. It is comparably inexpensive, time-saving, and follows the 3R principle, while allowing the identification of critical nanoparticle properties and optimal candidates for in vivo applications.PMID:36541426 | DOI:10.1002/biot.202200415
Source: Biotechnology Journal - December 21, 2022 Category: Biotechnology Authors: Michael Karimov Marlene Scherer Heike Franke Alexander Ewe Achim Aigner Source Type: research