Process economics evaluation of cell-free synthesis for the commercial manufacture of antibody drug conjugates.
This article is protected by copyright. All rights reserved. PMID: 33231912 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - November 24, 2020 Category: Biotechnology Authors: Stamatis C, Farid SS Tags: Biotechnol J Source Type: research

Optimization of a transient antibody expression platform towards high titer and efficiency.
This article is protected by copyright. All rights reserved. PMID: 33226178 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - November 23, 2020 Category: Biotechnology Authors: Greene E, Cazacu D, Tamot N, Castellano S, Datar A, Kronkaitis A, Gebhard D, Reed J, Mawson P, Florin L, Rossi N, Lauer A, Juckem L, Nixon A, Wenger T, Sen S Tags: Biotechnol J Source Type: research

A novel strategy of selective gene delivery by using a uniform magnetic field.
This article is protected by copyright. All rights reserved. PMID: 33226197 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - November 23, 2020 Category: Biotechnology Authors: Dateki M, Imamura O, Arai M, Shimizu H, Takishima K Tags: Biotechnol J Source Type: research

Quality Control Testing, Characterization and Critical Quality Attributes of AAV Vectors Used for Human Gene Therapy.
This article briefly reviews quality control methods for routine testing and supplemental characterization of AAV vectors for investigational product development. The relationship of vector and manufacturing process design with product critical quality attributes is discussed. This article is protected by copyright. All rights reserved. PMID: 33146911 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - November 4, 2020 Category: Biotechnology Authors: Wright JF Tags: Biotechnol J Source Type: research

Xylose Assimilation for the Efficient Production of Biofuels and Chemicals by Engineered Saccharomyces cerevisiae.
CONCLUSION: To boost the lignocellulosic biomass-based bioeconomy, much attention is expected to promote xylose-utilizing efficiency via reprogramming cellular regulatory networks, to attain robust co-fermentation of xylose and other cellulosic carbon sources under industrial conditions, and to exploit the advantageous traits of yeast xylose metabolism for producing diverse fuels and chemicals.. This article is protected by copyright. All rights reserved. PMID: 33135317 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - November 1, 2020 Category: Biotechnology Authors: Sun L, Jin YS Tags: Biotechnol J Source Type: research

Engineering Tobacco Mosaic Virus and its Virus-Like-Particles for Synthesis of Biotemplated Nanomaterials.
CONCLUSION: While control of VLP surface features is well-established, fewer tools exist to control VLP self-assembly, which limits efforts to control template uniformity and synthesis of certain templated nanomaterials. However, emerging advances in synthetic biology, machine learning, and other fields promise to accelerate efforts to control template uniformity and nanomaterial synthesis enabling more widescale industrial use of VLP-based biotemplates. This article is protected by copyright. All rights reserved. PMID: 33135368 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - November 1, 2020 Category: Biotechnology Authors: Lee KZ, Pussepitiyalage VB, Lee YH, Loesch-Fries S, Harris MT, Hemmati S, Solomon KV Tags: Biotechnol J Source Type: research

Preclinical Evaluation of a Novel TALEN Targeting CCR5 Confirms Efficacy and Safety in Conferring Resistance to HIV-1 Infection.
In conclusion, we successfully engineered a highly active and highly specific TALEN to disrupt CCR5, paving the way for its clinical application in hematopoietic stem cell grafts. This article is protected by copyright. All rights reserved. PMID: 33103367 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 25, 2020 Category: Biotechnology Authors: Romito M, Juillerat A, Kok YL, Hildenbeutel M, Rhiel M, Andrieux G, Geiger J, Rudolph C, Mussolino C, Duclert A, Metzner KJ, Duchateau P, Cathomen T, Cornu TI Tags: Biotechnol J Source Type: research

Advances in Lentivirus Purification.
This article is protected by copyright. All rights reserved. PMID: 33089626 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 22, 2020 Category: Biotechnology Authors: Moreira AS, Cavaco DG, Faria TQ, Alves PM, Carrondo MJT, Peixoto C Tags: Biotechnol J Source Type: research

Illuminating the Regenerative Properties of Stem Cells In Vivo with Bioluminescence Imaging.
This article is protected by copyright. All rights reserved. PMID: 33089922 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 22, 2020 Category: Biotechnology Authors: Madsen SD, Giler MK, Bunnell BA, O'Connor KC Tags: Biotechnol J Source Type: research

Engineering Native and Synthetic Pathways in Pseudomonas Putida for the Production of Tailored Polyhydroxyalkanoates ‡.
CONCLUSION: The potential of novel PHAs to disrupt existing and future market segments is closer to realization than ever before. We conclude the review by pinpointing challenges that currently hinder the wide adoption of bio-based PHAs, and we propose strategies towards programmable polymer biosynthesis from alternative substrates in engineered P. putida strains. This article is protected by copyright. All rights reserved. PMID: 33085217 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 21, 2020 Category: Biotechnology Authors: Mezzina MP, Manoli MT, Prieto MA, Nikel PI Tags: Biotechnol J Source Type: research

Adaptive Evolution in Producing Microtiter Cultivations Generates Genetically Stable Escherichia  coli Production Hosts for Continuous Bioprocessing.
This article is protected by copyright. All rights reserved. PMID: 33084246 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 20, 2020 Category: Biotechnology Authors: Elter A, Bogen JP, Hinz SC, Fiebig D, Palacios AM, Grzeschik J, Hock B, Kolmar H Tags: Biotechnol J Source Type: research

Humanization of Chicken-derived scFv Using Yeast Surface Display and NGS Data Mining.
This article is protected by copyright. All rights reserved. PMID: 33078896 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 20, 2020 Category: Biotechnology Authors: Elter A, Bogen JP, Hinz SC, Fiebig D, Palacios AM, Grzeschik J, Hock B, Kolmar H Tags: Biotechnol J Source Type: research

Emerging Strategies in Anticancer Combination Therapy Employing Silica-based Nanosystems.
This article is protected by copyright. All rights reserved. PMID: 33079451 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 20, 2020 Category: Biotechnology Authors: Castillo RR, Vallet-Regí M Tags: Biotechnol J Source Type: research

Improving Antibody Production In Stably Transfected CHO Cells by CRISPR-Cas9-mediated Inactivation of Genes Identified in a Large Scale Screen with Chinese Hamster-specific siRNAs.
This article is protected by copyright. All rights reserved. PMID: 33079482 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 20, 2020 Category: Biotechnology Authors: Lin PC, Liu R, Alvin K, Shahreel W, Murgolo N, Ye J, Du Z, Song Z Tags: Biotechnol J Source Type: research

The SSV-Seq 2.0 PCR-free method improves the sequencing of adeno-associated viral vector genomes containing GC-rich regions and homopolymers.
This article is protected by copyright. All rights reserved. PMID: 33064875 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 16, 2020 Category: Biotechnology Authors: Lecomte E, Saleun S, Bolteau M, Guy-Duché A, Adjali O, Blouin V, Penaud-Budloo M, Ayuso E Tags: Biotechnol J Source Type: research

Homologous Recombination Offers Advantages Over Transposition-Based Systems to Generate Recombinant Baculovirus for Adeno-Associated Viral Vector Production.
This article is protected by copyright. All rights reserved. PMID: 33067902 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 16, 2020 Category: Biotechnology Authors: Jacob A, Brun L, Gil PJ, Ménard L, Bouzelha M, Broucque F, Roblin A, Vandenberghe LH, Adjali O, Robin C, François A, Blouin V, Penaud-Budloo M, Ayuso E Tags: Biotechnol J Source Type: research

Dielectrophoretic Manipulation of Janus Particle in Conductive Media for Biomedical Applications.
This article is protected by copyright. All rights reserved. PMID: 33067912 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 16, 2020 Category: Biotechnology Authors: Lee M, Won JB, Jung DH, Kim J, Choi Y, Akyildiz K, Choi J, Kim K, Cho J, Yoon H, Koo HJ Tags: Biotechnol J Source Type: research

Assessing the Combinatorial Chemo-Photothermal Therapy Mediated by Sulfobetaine Methacrylate-Functionalized Nanoparticles in 2D and 3D In Vitro Cancer Models.
CONCLUSION: These results demonstrate the importance of using 3D spheroids during the in vitro screening of single/combinatorial therapies mediated by nanomaterials. This article is protected by copyright. All rights reserved. PMID: 33063471 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 15, 2020 Category: Biotechnology Authors: Mó I, Alves CG, de Melo-Diogo D, Lima-Sousa R, Correia IJ Tags: Biotechnol J Source Type: research

Dissolvable Gelatin-Based Microcarriers Generated Through Droplet Microfluidics for Expansion and Culture of Mesenchymal Stromal Cells.
This article is protected by copyright. All rights reserved. PMID: 33052012 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - October 13, 2020 Category: Biotechnology Authors: Ng EX, Wang M, Neo SH, Tee CA, Chen CH, Van Vliet KJ Tags: Biotechnol J Source Type: research

Separating empty and Full rAAV Particles Using Isocratic Anion Exchange Chromatography.
This article is protected by copyright. All rights reserved. PMID: 33002276 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 30, 2020 Category: Biotechnology Authors: Dickerson R, Argento C, Pieracci J, Bakhshayeshi M Tags: Biotechnol J Source Type: research

Chemoenzymatic Total Syntheses of Artonin I with an Intermolecular Diels-Alderase.
This article is protected by copyright. All rights reserved. PMID: 33002294 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 30, 2020 Category: Biotechnology Authors: Liu X, Yang J, Gao L, Zhang L, Lei X Tags: Biotechnol J Source Type: research

Intensified Downstream Processing of Monoclonal Antibodies Using Membrane Technology.
This article is protected by copyright. All rights reserved. PMID: 33006254 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 30, 2020 Category: Biotechnology Authors: Nadar S, Shooter G, Somasundaram B, Shave E, Baker K, Lua LHL Tags: Biotechnol J Source Type: research

Heparosan Chain Characterization: Sequential Depolymerization of E. Coli K5 Heparosan by a Bacterial Eliminase Heparin Lyase III and a Bacterial Hydrolase Heparanase Bp to Prepare Defined Oligomers.
This article is protected by copyright. All rights reserved. PMID: 33006278 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 30, 2020 Category: Biotechnology Authors: Datta P, Yan L, Awofiranye A, Dordick JS, Linhardt RJ Tags: Biotechnol J Source Type: research

Pseudomonas as Versatile Aromatics Cell Factory.
CONCLUSION: We expect further improvements regarding titer, rate, and yield through an integrated approach of strain and process engineering and an additional expansion of aromatic products and metabolizable substrates. This article is protected by copyright. All rights reserved. PMID: 32978889 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 24, 2020 Category: Biotechnology Authors: Schwanemann T, Otto M, Wierckx N, Wynands B Tags: Biotechnol J Source Type: research

The Degree and Length of O-glycosylation of Recombinant Proteins Produced in Pichia Pastoris Depends on the Nature of the Protein and the Process Type.
This study aims to reveal the influence of different cultivation strategies on O-mannosylation profiles in P. pastoris. Sixteen different model proteins, produced by different P. pastoris strains, were analyzed for their O-glycosylation profile. Based on the obtained data, human serum albumin (HSA) was chosen to be produced in fast and slow growth fed batch fermentations by using common promoters, PGAP and PAOX1 . After purification and protein digestion, glycopeptides were analyzed by LC/ESI-MS. In the samples expressed with PGAP it was found that the degree of glycosylation was slightly higher when a slow growth rate was...
Source: Biotechnology Journal - September 24, 2020 Category: Biotechnology Authors: Radoman B, Grünwald-Gruber C, Schmelzer B, Zavec D, Gasser B, Altmann F, Mattanovich D Tags: Biotechnol J Source Type: research

Production, Processing and Characterization of synthetic AAV Gene Therapy Vectors.
This article is protected by copyright. All rights reserved. PMID: 32975881 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 24, 2020 Category: Biotechnology Authors: Andari JE, Grimm D Tags: Biotechnol J Source Type: research

Localized Sampling Enables Monitoring of Cell State via Inline Electrospray Ionization Mass Spectrometry.
This article is protected by copyright. All rights reserved. PMID: 32975016 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 23, 2020 Category: Biotechnology Authors: Chilmonczyk MA, Doron G, Kottke PA, Culberson AL, Leguineche K, Guldberg RE, Horwitz EM, Fedorov AG Tags: Biotechnol J Source Type: research

Reconstitution of an Anti-HER2 Antibody Paratope by Grafting Dual CDR-Derived Peptides Onto a Small Protein Scaffold.
This article is protected by copyright. All rights reserved. PMID: 32975036 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 23, 2020 Category: Biotechnology Authors: See K, Kadonosono T, Ota Y, Miyamoto K, Yimchuen W, Kizaka-Kondoh S Tags: Biotechnol J Source Type: research

Multimodal Imaging and Soft X-Ray Tomography of Fluorescent Nanodiamonds in Cancer Cells.
This article is protected by copyright. All rights reserved. PMID: 32975037 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 23, 2020 Category: Biotechnology Authors: Reineck P, Abraham AN, Poddar A, Shukla R, Abe H, Ohshima T, Gibson BC, Dekiwadia C, Conesa JJ, Pereiro E, Gelmi A, Bryant G Tags: Biotechnol J Source Type: research

Evaluation of the Single-Use Fixed Bed Bioreactors in Scalable Virus Production.
This article will review the latest fully disposable fixed-bed bioreactors, compare the virus production in the different systems and discuss important manufacturing cost related topics. It is predicted that single-use fixed-bed bioreactors will receive even more attention in the field of viral vector manufacturing and commercialization, especially with the need for higher virus titers and virus yields. This article is protected by copyright. All rights reserved. PMID: 32971565 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 23, 2020 Category: Biotechnology Authors: Lesch HP, Valonen P, Karhinen M Tags: Biotechnol J Source Type: research

Microscale Perfusion-based Cultivation for Pichia pastoris Clone Screening Enables Accelerated and Optimized Recombinant Protein Production Processes.
This article is protected by copyright. All rights reserved. PMID: 32935449 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 14, 2020 Category: Biotechnology Authors: Totaro D, Radoman B, Schmelzer B, Rothbauer M, Steiger MG, Mayr T, Sauer M, Ertl P, Mattanovich D Tags: Biotechnol J Source Type: research

Doxorubicin-Loaded Physalis Mottle Virus Particles as a pH-Responsive Prodrug for Cancer Therapy.
This article is protected by copyright. All rights reserved. PMID: 32918857 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 11, 2020 Category: Biotechnology Authors: Hu H, Steinmetz NF Tags: Biotechnol J Source Type: research

Recent Advances in Biomaterial-Based High-Throughput Platforms.
CONCLUSIONS REACHED IN THE REVIEW: In this review article, we have focused on the recent developments in biomaterial-based platforms including the fabrication using both contact and non-contact methods. We then move on to utilization of such platforms for discovery of novel biomaterials exploiting the interaction of biological entities with surface and bulk properties. Finally, we elaborated on the application of the biomaterial-based high-throughput platforms in tissue engineering and regenerative medicine with a special focus on cancer and stem cell studies. CONCLUSION: The studies show encouraging applications of b...
Source: Biotechnology Journal - September 10, 2020 Category: Biotechnology Authors: Sarkar J, Kumar A Tags: Biotechnol J Source Type: research

Inhibition of E. coli host RNA Polymerase Allows Efficient Extracellular Recombinant Protein Production by Enhancing Outer Membrane Leakiness.
This article is protected by copyright. All rights reserved. PMID: 32915502 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 10, 2020 Category: Biotechnology Authors: Kastenhofer J, Rettenbacher L, Feuchtenhofer L, Mairhofer J, Spadiut O Tags: Biotechnol J Source Type: research

Isolation of Common Light Chain Antibodies from Immunized Chickens Using Yeast Biopanning and Fluorescence-Activated Cell Sorting.
This article is protected by copyright. All rights reserved. PMID: 32914549 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - September 9, 2020 Category: Biotechnology Authors: Bogen JP, Storka J, Yanakieva D, Fiebig D, Grzeschik J, Hock B, Kolmar H Tags: Biotechnol J Source Type: research

Modeling the Effect of Amino Acids and Copper on Monoclonal Antibody Productivity and Glycosylation: A Modular Approach.
This article is protected by copyright. All rights reserved. PMID: 32875683 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 31, 2020 Category: Biotechnology Authors: Luo Y, Lovelett RJ, Price JV, Radhakrishnan D, Barnthouse K, Hu P, Schaefer E, Cunningham J, Lee KH, Shivappa RB, Ogunnaike BA Tags: Biotechnol J Source Type: research

Mass Balance Model with Donnan Equilibrium Accurately Describes Unusual pH and Excipient Profiles during Diafiltration of Monoclonal Antibodies.
PMID: 32876400 [PubMed - in process] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 31, 2020 Category: Biotechnology Authors: Baek Y, Singh N, Arunkumar A, Borwankar A, Zydney AL Tags: Biotechnol J Source Type: research

Hydrogel-Based 3D Bioprinting for Bone and Cartilage Tissue Engineering.
This article is protected by copyright. All rights reserved. PMID: 32869529 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 30, 2020 Category: Biotechnology Authors: Abdollahiyan P, Oroojalian F, Mokhtarzadeh A, de la Guardia M Tags: Biotechnol J Source Type: research

Quantum Dots: A Review from Concept to Clinic.
This article is protected by copyright. All rights reserved. PMID: 32845071 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 25, 2020 Category: Biotechnology Authors: Kargozar S, Hoseini SJ, Milan PB, Hooshmand S, Kim HW, Mozafari M Tags: Biotechnol J Source Type: research

Self-Assembled Peptide Based Biocomposites for Near Infra-red Light Triggered Drug Release to Tumor Cells.
This article is protected by copyright. All rights reserved. PMID: 32845561 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 25, 2020 Category: Biotechnology Authors: Daso RE, Banerjee IA Tags: Biotechnol J Source Type: research

Directed Reaction Engineering Boosts Succinate Formation of Synechocystis sp. PCC 6803_ Δsll1625.
This article is protected by copyright. All rights reserved. PMID: 32845563 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 25, 2020 Category: Biotechnology Authors: Mock M, Schmid A, Bühler K Tags: Biotechnol J Source Type: research

Restoration and Modification of Magnetosome Biosynthesis by Internal Gene Acquisition in a Magnetotactic Bacterium.
This article is protected by copyright. All rights reserved. PMID: 32846013 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 25, 2020 Category: Biotechnology Authors: Arakaki A, Goto M, Maruyama M, Yoda T, Tanaka M, Yamagishi A, Yoshikuni Y, Matsunaga T Tags: Biotechnol J Source Type: research

Optimization of Alcohol Dehydrogenase for Industrial Scale Oxidation of Lactols.
This article is protected by copyright. All rights reserved. PMID: 32846049 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 25, 2020 Category: Biotechnology Authors: Bartsch S, Brummund J, Köpke S, Straatman H, Vogel A, Schürmann M Tags: Biotechnol J Source Type: research

Engineered Live Biotherapeutics: Progress and Challenges.
This article is protected by copyright. All rights reserved. PMID: 32770635 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 6, 2020 Category: Biotechnology Authors: Tan Y, Shen J, Si T, Ho CL, Li Y, Dai L Tags: Biotechnol J Source Type: research

Determinants of the Nucleotide Specificity in the Carbohydrate Epimerase Family 1.
This article is protected by copyright. All rights reserved. PMID: 32761842 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 5, 2020 Category: Biotechnology Authors: Van Overtveldt S, Da Costa M, Gevaert O, Joosten HJ, Beerens K, Desmet T Tags: Biotechnol J Source Type: research

Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector Production.
This article is protected by copyright. All rights reserved. PMID: 32762152 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 5, 2020 Category: Biotechnology Authors: Gränicher G, Tapia F, Behrendt I, Jordan I, Genzel Y, Reichl U Tags: Biotechnol J Source Type: research

Secretion of Pseudomonas Aeruginosa Lipoxygenase by Pichia Pastoris upon Glycerol Feed.
This article is protected by copyright. All rights reserved. PMID: 32749051 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 3, 2020 Category: Biotechnology Authors: Hashem C, Stolterfoht H, Rinnofner C, Steinberger S, Winkler M, Pichler H Tags: Biotechnol J Source Type: research

Pan-Genome-Scale Network Reconstruction: Harnessing Phylogenomics Increases the Quantity and Quality of Metabolic Models.
CONCLUSIONS: Curating ortholog and reaction databases at higher taxonomic-levels increases the quantity and quality of strain GENREs than the common practice of using model organism GENREs as templates. This pan-GENRE framework provides the ability to scale high-quality GENREs to more branches in the tree of life. This article is protected by copyright. All rights reserved. PMID: 32744423 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 2, 2020 Category: Biotechnology Authors: Correia K, Mahadevan R Tags: Biotechnol J Source Type: research

Recent Advances in the Construction of Flexible Sensors for Biomedical Applications.
This article is protected by copyright. All rights reserved. PMID: 32744777 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - August 2, 2020 Category: Biotechnology Authors: Zhou N, Liu T, Wen B, Gong C, Wei G, Su Z Tags: Biotechnol J Source Type: research

Microbial Electrosynthesis - An Inventory on Technology Readiness Level and Performance of Different Process Variants.
This article is protected by copyright. All rights reserved. PMID: 32738092 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - July 31, 2020 Category: Biotechnology Authors: Fruehauf HM, Enzmann F, Harnisch F, Ulber R, Holtmann D Tags: Biotechnol J Source Type: research