Demonstrating the Manufacture of Human CAR-T Cells in an Automated Stirred-tank Bioreactor.
This study is the first demonstration of human CAR-T cell production in stirred-tank bioreactors with the findings presenting significant implications and opportunities for larger-scale allogeneic CAR-T production. This article is protected by copyright. All rights reserved. PMID: 32592336 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - June 27, 2020 Category: Biotechnology Authors: Costariol E, Rotondi MC, Amini A, Hewitt CJ, Nienow AW, Heathman TRJ, Rafiq QA Tags: Biotechnol J Source Type: research

Magnetic Precipitation: A New Platform for Protein Purification.
This article is protected by copyright. All rights reserved. PMID: 32578939 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - June 24, 2020 Category: Biotechnology Authors: Santos RD, Iria I, Manuel AM, Leandro AP, Madeira CAC, Goncalves J, Carvalho AL, Roque AC Tags: Biotechnol J Source Type: research

Constructing E. coli Co-Cultures for de novo Biosynthesis of Natural Product Acacetin.
This article is protected by copyright. All rights reserved. PMID: 32573941 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - June 23, 2020 Category: Biotechnology Authors: Wang X, Shao A, Li Z, Policarpio L, Zhang H Tags: Biotechnol J Source Type: research

Mesenchymal Stem Cell-Derived Exosomes for Effective Cartilage Tissue Repair and Treatment of Osteoarthritis.
This article is protected by copyright. All rights reserved. PMID: 32559340 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - June 19, 2020 Category: Biotechnology Authors: Kim YG, Choi J, Kim K Tags: Biotechnol J Source Type: research

CRISPR with a Happy Ending: Non-Templated DNA Repair for Prokaryotic Genome Engineering.
This article is protected by copyright. All rights reserved. PMID: 32558098 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - June 17, 2020 Category: Biotechnology Authors: Finger-Bou M, Orsi E, van der Oost J, Staals RHJ Tags: Biotechnol J Source Type: research

Advances in Bacterial Biofilm Management for Maintaining Microbiome Homeostasis.
This article is protected by copyright. All rights reserved. PMID: 32510869 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - June 8, 2020 Category: Biotechnology Authors: Liu Z, Hong CJ, Yang Y, Dai L, Ho CL Tags: Biotechnol J Source Type: research

Hybrid Modeling and Intensified DoE: An Approach to Accelerate Upstream Process Characterization.
This article is protected by copyright. All rights reserved. PMID: 32501577 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - June 5, 2020 Category: Biotechnology Authors: Bayer B, Striedner G, Duerkop M Tags: Biotechnol J Source Type: research

A Site-Specific Integration Reporter System that Enables Rapid Evaluation of CRISPR/Cas9-mediated Genome Editing Strategies in CHO Cells.
This article is protected by copyright. All rights reserved. PMID: 32500600 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - June 4, 2020 Category: Biotechnology Authors: Hamaker NK, Lee KH Tags: Biotechnol J Source Type: research

Bioinspired Amorphous Nanoparticles of Polyphosphate and Ca-Carbonate Improve the Self-Healing Property of Cements.
This article is protected by copyright. All rights reserved. PMID: 32497376 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - June 4, 2020 Category: Biotechnology Authors: Tolba E, Wang X, Wang S, Neufurth M, Ackermann M, Schröder HC, Müller WEG Tags: Biotechnol J Source Type: research

Production of Substituted Styrene Bioproducts from Lignin and Lignocellulose Using Engineered Pseudomonas Putida KT2440.
This article is protected by copyright. All rights reserved. PMID: 32488970 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - June 2, 2020 Category: Biotechnology Authors: Williamson JJ, Bahrin N, Hardiman EM, Bugg TDH Tags: Biotechnol J Source Type: research

Inorganic Porous Nanoparticles for Drug Delivery in Antitumoral Therapy.
CONCLUSION: Porous inorganic nanoparticles have been designed to be accumulated in tumoral tissues; once there to recognize the target cell and finally, to release their payload in a controlled manner. This article is protected by copyright. All rights reserved. PMID: 32476279 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - June 1, 2020 Category: Biotechnology Authors: Parra-Nieto J, Del Cid MAG, de Cárcer IA, Baeza A Tags: Biotechnol J Source Type: research

Epitopes of Naturally Acquired and Vaccine-induced Anti-Ebola Virus Glycoprotein Antibodies in Single Amino Acid Resolution.
This article is protected by copyright. All rights reserved. PMID: 32463974 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - May 28, 2020 Category: Biotechnology Authors: Heidepriem J, Krähling V, Dahlke C, Wolf T, Klein F, Addo MM, Becker S, Loeffler FF Tags: Biotechnol J Source Type: research

The Effect of Container Surface Passivation on Aggregation of Intravenous Immunoglobulin Induced by Mechanical Shock.
This article is protected by copyright. All rights reserved. PMID: 32437086 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - May 21, 2020 Category: Biotechnology Authors: Movafaghi S, Wu H, Urdániz IMF, Bull DS, Kelly MD, Randolph TW, Goodwin AP Tags: Biotechnol J Source Type: research

Molecular Targets for the Testing of COVID-19.
Abstract The pandemic outbreaks of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), spread all over the world in a short period of time. Efficient identification of the infection by SARS-CoV-2 has been one of the most important tasks to facilitate all the following counter measurements in dealing with the infectious disease. In Taiwan, a COVID-19 Open Science Platform adheres to the spirit of open science: sharing sources, data, and methods to promote progress in academic research while corroborating findings from various disciplines has established in mi...
Source: Biotechnology Journal - May 18, 2020 Category: Biotechnology Authors: Yong SK, Su PC, Yang YS Tags: Biotechnol J Source Type: research

Emerging Technologies for the Electrochemical Detection of Bacteria.
This article is protected by copyright. All rights reserved. PMID: 32388907 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - May 10, 2020 Category: Biotechnology Authors: McEachern F, Harvey E, Merle G Tags: Biotechnol J Source Type: research

Photosynthetic Reduction of Xylose to Xylitol Using Cyanobacteria.
This article is protected by copyright. All rights reserved. PMID: 32388928 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - May 10, 2020 Category: Biotechnology Authors: Fan ES, Lu KW, Wen RC, Shen CR Tags: Biotechnol J Source Type: research

Transcription Factor ArcA is a Flux Sensor for the Oxygen Consumption Rate in Escherichia Coli.
This article is protected by copyright. All rights reserved. PMID: 32383263 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - May 8, 2020 Category: Biotechnology Authors: Nochino N, Toya Y, Shimizu H Tags: Biotechnol J Source Type: research

Fluorescent Biosensor of CDK5 Kinase Activity in Glioblastoma Cell Extracts and Living Cells.
This article is protected by copyright. All rights reserved. PMID: 32379380 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - May 7, 2020 Category: Biotechnology Authors: Peyressatre M, Laure A, Pellerano M, Boukhaddaoui H, Soussi I, Morris MC Tags: Biotechnol J Source Type: research

Gas-Sensing Transcriptional Regulators.
This article is protected by copyright. All rights reserved. PMID: 32362055 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - May 3, 2020 Category: Biotechnology Authors: Ganesh I, Gwon DA, Lee JW Tags: Biotechnol J Source Type: research

Bone-Inspired Tube Filling Decellularized Matrix of Toad Cartilage Provided an Osteoinductive Microenvironment for Mesenchymal Stem Cells to Facilitate the Radius Defect Repair of Rabbit.
This article is protected by copyright. All rights reserved. PMID: 32351022 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 30, 2020 Category: Biotechnology Authors: Xu HL, Yang WG, Chen PP, Chen R, Xue PP, Wang LF, Yuan JD, Yao Q, Chen B, Zhao YZ Tags: Biotechnol J Source Type: research

Micropipette Aspiration-Based Assessment of Single Channel Water Permeability.
This article is protected by copyright. All rights reserved. PMID: 32346982 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 29, 2020 Category: Biotechnology Authors: Boytsov D, Hannesschlaeger C, Horner A, Siligan C, Pohl P Tags: Biotechnol J Source Type: research

Anything but Conventional Chromatography Approaches in Bioseparation.
This article is protected by copyright. All rights reserved. PMID: 32333634 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 25, 2020 Category: Biotechnology Authors: Roque ACA, Pina AS, Azevedo AM, Aires-Barros R, Jungbauer A, Profio GD, Heng JYY, Haigh J, Ottens M Tags: Biotechnol J Source Type: research

Metal-organic framework composites for theragnostics and drug delivery applications.
This article is protected by copyright. All rights reserved. PMID: 32330358 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 24, 2020 Category: Biotechnology Authors: Osterrieth JWM, Fairen-Jimenez D Tags: Biotechnol J Source Type: research

13 C Metabolic Flux Analysis of Escherichia coli Engineered for Gamma-Aminobutyrate Production.
This article is protected by copyright. All rights reserved. PMID: 32319741 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 22, 2020 Category: Biotechnology Authors: Im DK, Hong J, Gu B, Sung C, Oh MK Tags: Biotechnol J Source Type: research

Progress and Concept for COVID-19 Vaccine Development.
PMID: 32304139 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 18, 2020 Category: Biotechnology Authors: Wu SC Tags: Biotechnol J Source Type: research

Modeling the Residence Time Distribution of Integrated Continuous Bioprocesses.
This article is protected by copyright. All rights reserved. PMID: 32302457 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 17, 2020 Category: Biotechnology Authors: Sencar J, Hammerschmidt N, Jungbauer A Tags: Biotechnol J Source Type: research

Crystal Contact Engineering Enables Efficient Capture and Purification of an Oxidoreductase by Technical Crystallization.
This article is protected by copyright. All rights reserved. PMID: 32302461 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 17, 2020 Category: Biotechnology Authors: Grob P, Huber M, Walla B, Hermann J, Janowski R, Niessing D, Hekmat D, Weuster-Botz D Tags: Biotechnol J Source Type: research

Oligonucleotides: Current trends and innovative applications in the synthesis, characterization and purification.
This article is protected by copyright. All rights reserved. PMID: 32298041 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 16, 2020 Category: Biotechnology Authors: Catani M, De Luca C, Alcântara JMG, Manfredini N, Perrone D, Marchesi E, Weldon R, Müller-Späth T, Cavazzini A, Morbidelli M, Sponchioni M Tags: Biotechnol J Source Type: research

Transporter Engineering for Microbial Manufacturing.
This article is protected by copyright. All rights reserved. PMID: 32298528 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 16, 2020 Category: Biotechnology Authors: Zhu Y, Zhou C, Wang Y, Li C Tags: Biotechnol J Source Type: research

Chemical Production from Methanol Using Natural and Synthetic Methylotrophs.
This article is protected by copyright. All rights reserved. PMID: 32281750 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 13, 2020 Category: Biotechnology Authors: Chen AY, Lan EI Tags: Biotechnol J Source Type: research

PASylation Enhances the Stability, Potency and Plasma Half-Life of Interferon α-2a: A Molecular Dynamics Simulation.
This article is protected by copyright. All rights reserved. PMID: 32277577 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 10, 2020 Category: Biotechnology Authors: Shamloo A, Rostami P, Mahmoudi A Tags: Biotechnol J Source Type: research

Temperature Down-Shift Modifies Expression of UPR-/ERAD-Related Genes and Enhances Production of a Chimeric Fusion Protein in CHO Cells.
This article is protected by copyright. All rights reserved. PMID: 32271992 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 9, 2020 Category: Biotechnology Authors: Torres M, Akhtar S, McKenzie EA, Dickson AJ Tags: Biotechnol J Source Type: research

Applications of Functional Metal-Organic Frameworks in Biosensors.
This article is protected by copyright. All rights reserved. PMID: 32271998 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 9, 2020 Category: Biotechnology Authors: Du L, Chen W, Zhu P, Tian Y, Chen Y, Wu C Tags: Biotechnol J Source Type: research

Biotechnological Production of Flavonoids: An Update on Plant Metabolic Engineering, Microbial Host Selection and Genetically Encoded Biosensors.
This article is protected by copyright. All rights reserved. PMID: 32267085 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 8, 2020 Category: Biotechnology Authors: Marsafari M, Samizadeh H, Rabiei B, Mehrabi A, Koffas M, Xu P Tags: Biotechnol J Source Type: research

Atomic Force Microscopy in Mechanoimmunology Analysis: A New Perspective for Cancer Immunotherapy.
This article is protected by copyright. All rights reserved. PMID: 32240578 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - April 2, 2020 Category: Biotechnology Authors: Kristi N, Gafur A, Kong L, Ma X, Ye Z, Wang G Tags: Biotechnol J Source Type: research

Overexpression of Transcription Factor ZNF1 of Glycolysis Improves Bioethanol Productivity Under High Glucose Concentration and Enhances Acetic Acid Tolerance of Saccharomyces Cerevisiae.
This article is protected by copyright. All rights reserved. PMID: 32196937 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - March 20, 2020 Category: Biotechnology Authors: Songdech P, Ruchala J, Semkiv MV, Jensen LT, Sibirny A, Ratanakhanokchai K, Soontorngun N Tags: Biotechnol J Source Type: research

Biotransformation of 5-Hydroxymethylfurfural to 2,5-Furandicarboxylic Acid by a Syntrophic Consortium of Engineered Synechococcus Elongatus and Pseudomonas Putida.
This article is protected by copyright. All rights reserved. PMID: 32181597 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - March 17, 2020 Category: Biotechnology Authors: Lin TY, Wen RC, Shen CR, Tsai SL Tags: Biotechnol J Source Type: research

Biotherapeutic Approaches in Atopic Dermatitis.
This article is protected by copyright. All rights reserved. PMID: 32176834 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - March 16, 2020 Category: Biotechnology Authors: Tham EH, Koh E, Common JEA, Hwang IY Tags: Biotechnol J Source Type: research

A Cyclin D1-Specific Single-Chain Variable Fragment Antibody that Inhibits HepG2 Cell Growth and Proliferation.
This article is protected by copyright. All rights reserved. PMID: 32170989 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - March 14, 2020 Category: Biotechnology Authors: Wu Y, Tang W, Cao Y, Jiang D, Zhao L, Zhao J, Zhang Y, Li C, Cheng C, Wang S, Yang F, Zhu X, Li G Tags: Biotechnol J Source Type: research

Microbial engineering for production of N-functionalized amino acids and amines.
This article is protected by copyright. All rights reserved. PMID: 32170807 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - March 13, 2020 Category: Biotechnology Authors: Mindt M, Walter T, Kugler P, Wendisch VF Tags: Biotechnol J Source Type: research

Multi-Omics Reveals Impact of Cysteine Feed Concentration and Resulting Redox Imbalance on Cellular Energy Metabolism and Specific Productivity in CHO Cell Bioprocessing.
This article is protected by copyright. All rights reserved. PMID: 32170810 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - March 13, 2020 Category: Biotechnology Authors: Ali AS, Chen R, Raju R, Kshirsagar R, Gilbert A, Zang L, Karger BL, Ivanov AR Tags: Biotechnol J Source Type: research

Recent Advances in Sustainable Plastic Upcycling and Biopolymers.
This article is protected by copyright. All rights reserved. PMID: 32162832 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - March 12, 2020 Category: Biotechnology Authors: Sohn YJ, Kim HT, Baritugo KA, Jo SY, Song HM, Park SY, Park SK, Pyo J, Cha HG, Kim H, Na JG, Park C, Choi JI, Joo JC, Park SJ Tags: Biotechnol J Source Type: research

Nanobiohybrid Material-Based Bioelectronic Devices.
This article is protected by copyright. All rights reserved. PMID: 32143237 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - March 6, 2020 Category: Biotechnology Authors: Yoon J, Shin M, Lim J, Kim DY, Lee T, Choi JW Tags: Biotechnol J Source Type: research

Crosstalk Between Endo/Exocytosis and Autophagy in Health and Disease.
This article is protected by copyright. All rights reserved. PMID: 32143239 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - March 6, 2020 Category: Biotechnology Authors: Papandreou ME, Tavernarakis N Tags: Biotechnol J Source Type: research

Systematic and Comparative Evaluation of Software Programs for Template-Based Modeling of Protein Structures.
This article is protected by copyright. All rights reserved. PMID: 32130758 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - March 4, 2020 Category: Biotechnology Authors: Jang WD, Lee SM, Kim HU, Lee SY Tags: Biotechnol J Source Type: research

Synthesis of Injectable Shear-Thinning Biomaterials of Various Compositions of Gelatin and Synthetic Silicate Nanoplatelet.
This article is protected by copyright. All rights reserved. PMID: 32107862 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - February 27, 2020 Category: Biotechnology Authors: Xue C, Xie H, Eichenbaum J, Chen Y, Wang Y, van den Dolder FW, Lee J, Lee K, Zhang S, Sun W, Sheikhi A, Ahadian S, Ashammakhi N, Dokmeci MR, Kim HJ, Khademhosseini A Tags: Biotechnol J Source Type: research

Modulation of the Purine Pathway for Riboflavin Production in Flavinogenic Recombinant Strain of the Yeast Candida Famata.
This article is protected by copyright. All rights reserved. PMID: 32087089 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - February 22, 2020 Category: Biotechnology Authors: Dmytruk KV, Ruchala J, Fedorovych DV, Ostapiv RD, Sibirny AA Tags: Biotechnol J Source Type: research

A Critical Review of Genome Editing and Synthetic Biology Applications in Metabolic Engineering of Microalgae and Cyanobacteria.
This article is protected by copyright. All rights reserved. PMID: 32080963 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - February 20, 2020 Category: Biotechnology Authors: Ng IS, Keskin BB, Tan SI Tags: Biotechnol J Source Type: research

Mammalian Pericardium-Based Bioprosthetic Materials in Xenotransplantation and Tissue Engineering.
This article is protected by copyright. All rights reserved. PMID: 32077589 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - February 20, 2020 Category: Biotechnology Authors: Grebenik ЕA, Gafarova ER, Istranov LP, Istranova ЕV, Ma X, Xu J, Guo W, Atala A, Timashev PS Tags: Biotechnol J Source Type: research

Improvement of Intracellular Traffic System by Overexpression of KDEL Receptor 1 in Antibody-Producing CHO Cells.
This article is protected by copyright. All rights reserved. PMID: 32073237 [PubMed - as supplied by publisher] (Source: Biotechnology Journal)
Source: Biotechnology Journal - February 19, 2020 Category: Biotechnology Authors: Samy A, Kaneyoshi K, Omasa T Tags: Biotechnol J Source Type: research