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Total 393 results found since Jan 2013.

Role of < em > Dgat2 < /em > in Glucose Uptake and Fatty Acid Metabolism in C2C12 Skeletal Myotubes
J Microbiol Biotechnol. 2023 Aug 18;33(12):1-9. doi: 10.4014/jmb.2307.07018. Online ahead of print.ABSTRACTAcyl-coenzyme A (CoA):diacylglycerol acyltransferase 2 (DGAT2) catalyzes the last stage of triacylglycerol (TAG) synthesis, a process that forms ester bonds with diacylglycerols (DAG) and fatty acyl-CoA substrates. The enzymatic role of Dgat2 has been studied in various biological species. Still, the full description of how Dgat2 channels fatty acids in skeletal myocytes and the consequence thereof in glucose uptake have yet to be well established. Therefore, this study explored the mediating role of Dgat2 in glucose ...
Source: Journal of Microbiology and Biotechnology - August 30, 2023 Category: Biotechnology Authors: So Young Bu Source Type: research

Study on the Role of Mitophagy Receptor PHB2 in Doubly Uniparental Inheritance of Hyriopsis cumingii
Mar Biotechnol (NY). 2023 Aug 18. doi: 10.1007/s10126-023-10240-5. Online ahead of print.ABSTRACTIn bivalves, the heterogeneity of mitochondrial DNA and its unique mode of transmission have been the focus of attention, which is called doubly uniparental inheritance (DUI). Prohibitin-2 (phb2) is a mitochondrial inner membrane protein that is a key mitophagy receptor for parental mitochondrial removal. Hyriopsis cumingii is a freshwater bivalve in China, the full-length cDNA of H. cumingii phb2 (named Hcphb2) is 2917 bp and encodes a total of 300 amino acids, a highly conserved sequence. Hcphb2 was highly expressed in the ov...
Source: Marine Biotechnology - August 18, 2023 Category: Biotechnology Authors: Yayu Wang Xiaoyue Zhu Yang Gu Zongyu Liu Yingrui Mao Xiaojun Liu Zhiyi Bai Guiling Wang Jiale Li Source Type: research

Development of peptide-based ratiometric fluorescent probe for sensing heparan sulfate and heparin in aqueous solutions at physiological pH and quantitative detection of heparan sulfate in live cells
This study presents the first ratiometric fluorescent probe capable of quantitatively detecting HS levels in aqueous solutions and live cells. The unique properties of peptide-based probe 3 make it a valuable tool for studying HS biology and potentially for diagnostic applications in various biological systems.PMID:37595478 | DOI:10.1016/j.bios.2023.115595
Source: Biosensors and Bioelectronics - August 18, 2023 Category: Biotechnology Authors: Sumita Subedi Hyun Jung Hwang Donghee Kang Pramod Kumar Mehta Nayeon Kim Hyojin Park Jae-Seon Lee Keun-Hyeung Lee Source Type: research

Study on the Role of Mitophagy Receptor PHB2 in Doubly Uniparental Inheritance of Hyriopsis cumingii
Mar Biotechnol (NY). 2023 Aug 18. doi: 10.1007/s10126-023-10240-5. Online ahead of print.ABSTRACTIn bivalves, the heterogeneity of mitochondrial DNA and its unique mode of transmission have been the focus of attention, which is called doubly uniparental inheritance (DUI). Prohibitin-2 (phb2) is a mitochondrial inner membrane protein that is a key mitophagy receptor for parental mitochondrial removal. Hyriopsis cumingii is a freshwater bivalve in China, the full-length cDNA of H. cumingii phb2 (named Hcphb2) is 2917 bp and encodes a total of 300 amino acids, a highly conserved sequence. Hcphb2 was highly expressed in the ov...
Source: Marine Biotechnology - August 18, 2023 Category: Biotechnology Authors: Yayu Wang Xiaoyue Zhu Yang Gu Zongyu Liu Yingrui Mao Xiaojun Liu Zhiyi Bai Guiling Wang Jiale Li Source Type: research

Proliferation-Related Features of the Human Mesenchymal Stem Cells Derived from Palatine Tonsils, Adipose Tissues, and Bone Marrow
Conclusion:Our study compared MSCs of different origins to better understand the similarities and differences among these cell types.
Source: Tissue Engineering and Regenerative Medicine - August 18, 2023 Category: Biotechnology Source Type: research

Multiple suppressing small interfering rna for cancer treatment - application to triple-negative breast cancer
This article is protected by copyright. All rights reserved.PMID:37478121 | DOI:10.1002/biot.202300060
Source: Biotechnology Journal - July 21, 2023 Category: Biotechnology Authors: Jaewook Lee Jang Hyuk Bang Yeong Chae Ryu Byeong Hee Hwang Source Type: research