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Total 1545 results found since Jan 2013.

GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis
ConclusionsGCH1 inhibited ferroptosis in LPS-stimulated macrophages, reduced macrophage toward to M1 polarization and inflammatory response.
Source: Inflammation Research - September 21, 2023 Category: Research Source Type: research

FOXO1 regulates NLRP3 inflammasome proteins in LPS-induced cardiotoxicity
CONCLUSION: FOXO1 overexpression attenuated apoptosis, ROS generation, and inflammation, whereas FOXO1 inhibition aggravated LPS-induced cardiomyocyte injury via the NLRP3 inflammasome signaling pathway.PMID:37692952 | PMC:PMC10492091
Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Hui Zhao Lingcun Qin Ruyi Wang Dejie Qu Suting Li Source Type: research

Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells
CONCLUSION: We propose that DNA demethylation followed by increased expression of key genes may be one of the factors responsible for the progression and maintenance of the resistant cell phenotype that includes exosome-induced resistance.PMID:37645026 | PMC:PMC10460766 | DOI:10.34172/bi.2023.27490
Source: BioImpacts - August 30, 2023 Category: Research Authors: Yuri Yu Shchegolev Danila V Sorokin Alexander M Scherbakov Olga E Andreeva Diana I Salnikova Ekaterina I Mikhaevich Margarita V Gudkova Mikhail A Krasil'nikov Source Type: research