FOXO1 regulates NLRP3 inflammasome proteins in LPS-induced cardiotoxicity

CONCLUSION: FOXO1 overexpression attenuated apoptosis, ROS generation, and inflammation, whereas FOXO1 inhibition aggravated LPS-induced cardiomyocyte injury via the NLRP3 inflammasome signaling pathway.PMID:37692952 | PMC:PMC10492091

Source: American Journal of Translational Research - September 11, 2023 Category: Research Authors: Hui Zhao Lingcun Qin Ruyi Wang Dejie Qu Suting Li Source Type: research