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Nutrition: Fish

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Total 107 results found since Jan 2013.

A mannose receptor is involved in the anti-Vibrio defense of red swamp crayfish
Publication date: Available online 9 August 2018Source: Fish & Shellfish ImmunologyAuthor(s): Xin Man, Xin-Tong Pan, Hong-Wei Zhang, Yue Wang, Xin-Cang Li, Xiao-Wen ZhangAbstractMannose receptor (MR), a member of pattern-recognition receptors (PRRs), is the first MR family member to be discovered that plays a critical role in immunity. The function of MRs has been reported in mammals and teleosts while none in invertebrates. In the present study, we identified a MR-like gene (designated as PcMR) from red swamp crayfish, Procambarus clarkii. The PcMR cDNA is 6848 bp long with a 6288 bp open reading frame that encodes a poly...
Source: Fish and Shellfish Immunology - August 10, 2018 Category: Biology Source Type: research

Identification and characterization of a novel PRR of fibrinogen-related protein in Apostichopus japonicus
Publication date: Available online 6 August 2018Source: Fish & Shellfish ImmunologyAuthor(s): Liting Jiang, Yina Shao, Ronglian Xing, Chenghua Li, Yi Cui, Weiwei Zhang, Xuelin ZhaoAbstractFibrinogen-related proteins (FREPs) play important roles in innate immunity by recognizing pathogen associated molecular patterns on pathogenic bacteria surfaces via conserved fibrinogen-like domain (FBG). In this paper, the full-length cDNA of Apostichopus japonicus FREP (designated as AjFREP) was cloned combined with rapid amplification of cDNA ends (RACE) and transcriptome sequencing. The full-length cDNA of AjFREP was of 2110 bp with ...
Source: Fish and Shellfish Immunology - August 6, 2018 Category: Biology Source Type: research

Molecular cloning and functional characterisation of NLRX1 in grass carp (Ctenopharyngodon idella)
Publication date: October 2018Source: Fish & Shellfish Immunology, Volume 81Author(s): Pengfei Chu, Libo He, Yangyang Li, Rong Huang, Lanjie Liao, Yongming Li, Zuoyan Zhu, Yaping WangAbstractThe nucleotide-binding domain and leucine-rich-repeat-containing (NLR) proteins regulate innate immunity. Although the positive regulatory impact of NLRs is clear, their inhibitory roles are not well defined. In the present study, the NLR family gene NLRX1 from grass carp (Ctenopharyngodon idella) was cloned and characterised. NLRX1 was widely expressed in all tissues examined, albeit at varying levels. After exposure to the grass carp...
Source: Fish and Shellfish Immunology - July 18, 2018 Category: Biology Source Type: research

Functional domains of Litopenaeus vannamei transglutaminase and their involvement in immunoregulation in shrimp
Publication date: October 2018Source: Fish & Shellfish Immunology, Volume 81Author(s): Zhou Zheng, Wenning Xu, Jude Juventus Aweya, Mingqi Zhong, Shangjie Liu, Jingsheng Lun, Jiehui Chen, Yueling ZhangAbstractShrimps, which mainly rely on their innate immune system to response to infectious pathogens, have clottable proteins as an important component of this system. While transglutaminases (TGase) are found in Litopenaeus vannamei and constitute part of the coagulation system, the specific immune-related roles played by its functional domains in the immunoregulation of shrimp has not been well understood. In the present st...
Source: Fish and Shellfish Immunology - July 18, 2018 Category: Biology Source Type: research

Eriocheir sinensis microRNA-7 targets crab Myd88 to enhance white spot syndrome virus replication
In this study, the function of microRNA-7 (miR-7) in host-virus interaction was investigated. Replication of White spot syndrome virus (WSSV) was enhanced with the overexpression of miR-7 and inhibited with the downregulation of miR-7 by using anti-miRNA oligonucleotide AMO-miR-7. The target gene of miR-7 was predicted using bioinformatics methods. Results showed that crab myeloid differentiation factor 88 (Myd88) could be targeted by miR-7. When the expression of Myd88 was knocked down by sequence-specific siRNA, WSSV copies in crabs were significantly increased. Further findings revealed that knockdown of Myd88, Tube, or...
Source: Fish and Shellfish Immunology - July 5, 2018 Category: Biology Source Type: research

Fish oil alleviates liver injury induced by intestinal ischemia/reperfusion via AMPK/SIRT-1/autophagy pathway.
CONCLUSION: Our study indicates that FO may protect the liver against intestinal I/R induced injury through the AMPK/SIRT-1/autophagy pathway. PMID: 29467553 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - February 21, 2018 Category: Gastroenterology Authors: Jing HR, Luo FW, Liu XM, Tian XF, Zhou Y Tags: World J Gastroenterol Source Type: research

LncRNA MALAT1 regulates oxLDL-induced CD36 expression via activating β-catenin.
In conclusion, oxLDL induced MALAT1 transcription and MALAT1 recruits β-catenin to binding sites on the CD36 promoter to induce CD36 expression, which enhances lipid uptake in macrophages. PMID: 29258822 [PubMed - as supplied by publisher]
Source: Biochemical and Biophysical Research communications - December 16, 2017 Category: Biochemistry Authors: Huangfu N, Xu Z, Zheng W, Wang Y, Cheng J, Chen X Tags: Biochem Biophys Res Commun Source Type: research

Regulation of hepatic lipid deposition by phospholipid in large yellow croaker.
Abstract Dietary phospholipid (PL) supplementation has been shown to reduce lipid accumulation in the tissues of farmed fish; however, the mechanisms underlying this effect are largely unknown. Thus, the present study was conducted to evaluate the potential impacts of PL on hepatic lipid metabolism both in vivo and in vitro. For in vivo study, four experimental diets - low lipid and low PL diet, as control diet (LL-LP diet, containing 12 % lipid and 1·5 % PL), low-lipid and high-PL diet (containing 12 % lipid and 8 % PL), high-lipid and low-PL diet (HL-LP diet, containing 20 % lipid and 1·5 % PL) and high-lipid ...
Source: The British Journal of Nutrition - December 4, 2017 Category: Nutrition Authors: Cai Z, Mai K, Ai Q Tags: Br J Nutr Source Type: research

Long non ‐coding RNA LOC554202 modulates chordoma cell proliferation and invasion by recruiting EZH2 and regulating miR‐31 expression
ConclusionOur results suggest that LOC554202 may play an important role in the progression of chordoma by the direct upregulation of EZH2 and indirect promotion of RNF144B via miR‐31.
Source: Cell Proliferation - September 30, 2017 Category: Cytology Authors: Xianli Ma, Shengjin Qi, Zhenying Duan, Hongzhan Liao, Baohua Yang, Wenbo Wang, Jie Tan, Qinghua Li, Xuewei Xia Tags: ORIGINAL ARTICLE Source Type: research

Grass carp (Ctenopharyngodon idella) STAT3 regulates the eIF2 α phosphorylation through interaction with PKR.
Grass carp (Ctenopharyngodon idella) STAT3 regulates the eIF2α phosphorylation through interaction with PKR. Dev Comp Immunol. 2017 Sep 12;: Authors: Wang L, Wu Z, Huang Q, Huang K, Qi G, Wu C, Mao H, Xu X, Wang H, Hu C Abstract In mammals, STAT3 (Signal transducer and activator of transcription 3) plays an important role in growth, multiplication, differentiation and participates in inflammation, tumorigenesis, metabolic disorders and immune response. STAT3 is a protein that shuttles between the nucleus and cytoplasm. Compared to the STAT3 in cell nucleus, we did not know the function of STAT3 in cy...
Source: Developmental and Comparative Immunology - September 12, 2017 Category: Allergy & Immunology Authors: Wang L, Wu Z, Huang Q, Huang K, Qi G, Wu C, Mao H, Xu X, Wang H, Hu C Tags: Dev Comp Immunol Source Type: research

Thymosin β4 is involved in the antimicrobial immune response of Golden pompano, Trachinotus ovatus
Publication date: October 2017 Source:Fish & Shellfish Immunology, Volume 69 Author(s): Yun Sun, Xiaojuan Chen, Yue Xu, Qiaohong Liu, Xue Jiang, Shifeng Wang, Weiliang Guo, Yongcan Zhou Thymosin beta belongs to the thymosin family, which consists of a series of highly conserved peptides involved in various biological processes. In teleosts, understanding of the immunological functions of thymosin beta is limited, particularly in vivo, which is essentially unknown. In the current study, we cloned and identified thymosin beta 4 from the teleost fish Golden pompano (Trachinotus ovatus), which we have named TroTβ4. ...
Source: Fish and Shellfish Immunology - August 30, 2017 Category: Biology Source Type: research

MicroRNA-30a ameliorates hepatic fibrosis by inhibiting Beclin1-mediated autophagy.
In conclusion, miR-30a is down-regulated in hepatic fibrosis models and its overexpression prevents liver fibrogenesis by directly suppressing Beclin1-mediated autophagy; therefore, miR-30a may be a new potential therapeutic target for controlling hepatic fibrosis. PMID: 28766848 [PubMed - as supplied by publisher]
Source: J Cell Mol Med - August 1, 2017 Category: Molecular Biology Authors: Chen J, Yu Y, Li S, Liu Y, Zhou S, Cao S, Yin J, Li G Tags: J Cell Mol Med Source Type: research

Association of FGFR1 with ER αmaintains ligand-independent ER transcription and mediates resistance to estrogen deprivation in ER+ breast cancer.
Conclusions: These data suggest the ERα pathway remains active in estrogen-deprived ER+/FGFR1-amplified breast cancers. Therefore, these tumors are endocrine resistant and should be candidates for treatment with combinations of ER and FGFR antagonists. PMID: 28751448 [PubMed - as supplied by publisher]
Source: Clinical Cancer Research - July 27, 2017 Category: Cancer & Oncology Authors: Formisano L, Stauffer KM, Young CD, Bhola NE, Guerrero-Zotano AL, Jansen VM, Estrada MM, Hutchinson KE, Giltnane JM, Schwarz LJ, Lu Y, Balko JM, Deas O, Cairo S, Judde JG, Mayer IA, Sanders M, Dugger TC, Bianco R, Stricker T, Arteaga CL Tags: Clin Cancer Res Source Type: research

Subcritical water-hydrolyzed fish collagen ameliorates survival of endotoxemic mice by inhibiting HMGB1 release in a HO-1-dependent manner.
Abstract To investigate potential mechanisms underlying the bioactivity of hydrolyzed fish collagen, we examined the anti-inflammatory actions of subcritical water-hydrolyzed fish collagen (SWFC) in lipopolysaccharide (LPS)-triggered inflammation and endotoxemia. SWFC markedly inhibited LPS-stimulated release of high mobility group box 1 (HMGB1) in murine RAW264.7 macrophages, along with decreased cytosolic translocation of HMGB1. Both the protein and mRNA levels of heme oxygenase-1 (HO-1) were significantly upregulated in SWFC-treated RAW 264.7 cells in an Nrf2-dependent manner. In line with these effects of SWFC...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - July 13, 2017 Category: Drugs & Pharmacology Authors: Ahn MY, Hwang JS, Ham SA, Hur J, Jo Y, Lee S, Choi MJ, Han SG, Seo HG Tags: Biomed Pharmacother Source Type: research