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Total 107 results found since Jan 2013.
MicroRNA ‐30a ameliorates hepatic fibrosis by inhibiting Beclin1‐mediated autophagy
In conclusion, miR‐30a is down‐regulated in hepatic fibrosis models and its overexpression prevents liver fibrogenesis by directly suppressing Beclin1‐mediated autophagy; therefore, miR‐30a may be a new potential therapeutic target for controlling hepatic fibrosis.
Source: Journal of Cellular and Molecular Medicine - July 1, 2017 Category: Molecular Biology Authors: Jianliang Chen, Yue Yu, Shu Li, Yuting Liu, Shu Zhou, Shouji Cao, Jie Yin, Guoqiang Li Tags: Original Article Source Type: research
Function analysis of fish Tollip gene in response to virus infection
Publication date: December 2015 Source:Fish & Shellfish Immunology, Volume 47, Issue 2 Author(s): Jingguang Wei, Meng Xu, Xiuli Chen, Ping Zhang, Pingfei Li, Shina Wei, Yang Yan, Qiwei Qin Toll-interacting protein (Tollip) is one of the important regulatory proteins of Toll-like receptor (TLR) signaling pathways. In previous studies, a Tollip sequence of grouper (Epinephelus coioides) was identified and the signal transduction functions of Tollip were studied. However, the response of Tollip to virus infection has not been characterized from grouper. In the present paper, the Tollip homolog (EtTollip) fro...
Source: Fish and Shellfish Immunology - October 31, 2015 Category: Biology Source Type: research
