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Infectious Disease: Pandemics
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Total 136914 results found since Jan 2013.
How does the Immunological System Change during the SARS-COV-2 Attack? A Clue for the New Immunotherapy Discovery
Curr Med Chem. 2023 Sep 18. doi: 10.2174/0929867331666230918092749. Online ahead of print.ABSTRACTThe COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-COV-2) is one of the biggest unsolved global problems of the 21st century for which there has been no definitive cure yet. Like other respiratory viruses, SARS-COV-2 triggers the host immunity dramatically, causing dysfunction in the immune system, both innate and adaptive, which is a common feature of COVID-19 patients. Evidence shows that in the early stages of COVID-19, the immune system is suppressed while it is overactive in severe p...
Source: Current Medicinal Chemistry - September 19, 2023 Category: Chemistry Authors: Mohammad Mahdi Hajihasani Najmeh Kaffash Farkhad Ali Mahmoudi Amirhossein Sahebkar Source Type: research
A Review of Studies on the Covid-19 Pandemic and the Psychological Effects of Related Measures on Children, Youth and Parents
Turk Psikiyatri Derg. 2023 Fall;34(3):202-214. doi: 10.5080/u25936.ABSTRACTPandemics are social events that affect individuals' lives in many ways and have a significant impact on the mental health of masses. Pandemics and measures taken to combat these epidemics affect children and young people as well as adults. The purpose of the current review is to compile studies that have been conducted on the psychological effects of the COVID-19 pandemic and related measures on children, youth, and parents, and use the findings to shed light on future studies. In this review, 35 studies that were determined as a result of a compre...
Source: Turkish Journal of Psychiatry - September 19, 2023 Category: Psychiatry Authors: Burcu Altin G ülsen Erden Source Type: research
Evaluation of the Impact of the COVID-19 Pandemic on Cystic Echinococcosis Indirect Hemagglutination Test Dynamics: A Single-center Experience
CONCLUSION: A significant decrease was observed in the rate of IHA positivity during the pandemic period. The status of no increase in positivity rates despite a significant decrease in IHA tests makes us think that the diagnosis may be missed in some patients or that there could be disruptions in their follow-up. For this reason, in order to continue the fight successfully against CE, which is an important public health problem for our country, early diagnosis and regular follow-ups should be emphasized with educations, and the laboratory-clinician communication should be strengthened in order to use tests more efficientl...
Source: Turkish Society for Parasitology - September 19, 2023 Category: Parasitology Authors: Özlem Ulusan Bağcı Source Type: research
A Review of Studies on the Covid-19 Pandemic and the Psychological Effects of Related Measures on Children, Youth and Parents
Turk Psikiyatri Derg. 2023 Fall;34(3):202-214. doi: 10.5080/u25936.ABSTRACTPandemics are social events that affect individuals' lives in many ways and have a significant impact on the mental health of masses. Pandemics and measures taken to combat these epidemics affect children and young people as well as adults. The purpose of the current review is to compile studies that have been conducted on the psychological effects of the COVID-19 pandemic and related measures on children, youth, and parents, and use the findings to shed light on future studies. In this review, 35 studies that were determined as a result of a compre...
Source: Turk Psikiyatri Dergisi - September 19, 2023 Category: Psychiatry Authors: Burcu Altin G ülsen Erden Source Type: research
A large survey on COVID-19 vaccination in patients with Parkinson's disease and healthy population
CONCLUSIONS: The COVID-19 vaccination rate was remarkably lower in PD patients than healthy individuals in China. The approved vaccines have shown an acceptable safety profile. Our findings would offer a reference to guide future clinical decision-making of COVID-19 vaccination and improve the immunization management of PD patients.PMID:37726180 | DOI:10.1016/j.vaccine.2023.09.002
Source: Vaccine - September 19, 2023 Category: Allergy & Immunology Authors: Chao Han Zhen Zhen Zhao Piu Chan Fang Li Chun Ling Chi Xin Zhang Yan Zhao Jing Chen Jing Hong Ma Source Type: research
Preclinical evaluation of a SARS-CoV-2 variant B.1.351-based candidate DNA vaccine
Vaccine. 2023 Sep 17:S0264-410X(23)01091-5. doi: 10.1016/j.vaccine.2023.09.021. Online ahead of print.ABSTRACTThe SARS-CoV-2 pandemic revealed the critical shortfalls of global vaccine availability for emergent pathogens and the need for exploring additional vaccine platforms with rapid update potential in response to new variants. Thus, it remains essential, for the present evolving SARS-CoV-2/Covid-19 and future pandemics, to continuously develop and characterize new and different vaccine platforms. Here, we describe an expression-optimized DNA vaccine candidate based on the SARS-CoV-2 spike protein of the Beta variant (...
Source: Vaccine - September 19, 2023 Category: Allergy & Immunology Authors: Ria Lassauni ère Charlotta Polacek Jeanette Linnea Tingstedt Anders Fomsgaard Source Type: research
Maternal Mental Health, COVID-19-Related Distress, and Disruptions in Lifestyle Behaviors Among Postpartum Mothers With a Previous Hypertensive Disorder of Pregnancy
CONCLUSION: Monitoring PTSD symptoms may be vital in supporting mothers with hypertensive disorders of pregnancy in making lifestyle changes to prevent cardiovascular disease.PMID:37723619 | DOI:10.1097/JCN.0000000000001038
Source: The Journal of Cardiovascular Nursing - September 19, 2023 Category: Nursing Authors: Jewel Scott Alisse Hauspurg Esa M Davis Samantha Bryan Janet M Catov Source Type: research
Neurological telerehabilitation in the COVID-19 era – current perspectives through a bibliometric analysis
ConclusionA greater interest in the subject was observed in China with greater relevance of journals and institutions focused on neurology. However, despite telerehabilitation being an effective alternative in the context of the pandemic, few studies have explored this modality.
Source: Frontiers in Neurology - September 19, 2023 Category: Neurology Source Type: research
The necessity of proactive measures from healthcare providers highlighted by delayed breast cancer diagnosis due to COVID-19: A case report
Clin Case Rep. 2023 Sep 15;11(9):e7919. doi: 10.1002/ccr3.7919. eCollection 2023 Sep.ABSTRACTKEY CLINICAL MESSAGE: During disasters, multiple factors can cause significant delays in medical visits. Regular patient monitoring, high-risk individual alerts, and telemedicine enhancements can potentially alleviate these issues and ensure timely interventions.ABSTRACT: During the COVID-19 pandemic, a Japanese woman in her 70s delayed her regular breast cancer checkup for over 2 years. During disasters, health priorities tend to decline, necessitating proactive measures from healthcare providers, such as augmenting collaboration ...
Source: Clinical Breast Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Yudai Kaneda Akihiko Ozaki Mira Namba Toyoaki Sawano Masahiro Wada Hiroaki Saito Yoshiaki Kanemoto Tomohiro Kurokawa Masaharu Tsubokura Kazunoshin Tachibana Tetsuya Tanimoto Tohru Ohtake Tomozo Ejiri Hiroaki Shimmura Norio Kanzaki Source Type: research
ASO Visual Abstract: COVID-19 Pandemic Did Not Influence the Number of Oncologic and Emergency Surgeries-A Retrospective Cohort Study from a Tertiary Hospital in Austria
Ann Surg Oncol. 2023 Sep 18. doi: 10.1245/s10434-023-14330-5. Online ahead of print.NO ABSTRACTPMID:37721692 | DOI:10.1245/s10434-023-14330-5
Source: Ann Oncol - September 18, 2023 Category: Cancer & Oncology Authors: Lukas Gasteiger Gabriel Putzer Elisabeth Hoerner Michael Joannidis Timo Mayerhoefer Tobias Hell Ottokar Stundner Judith Martini Source Type: research
Social Isolation of Older Adults, Family, and Formal Caregivers During the COVID-19 Pandemic: Stories and Solutions Through Participatory Action Research
Can J Aging. 2023 Sep 18:1-14. doi: 10.1017/S071498082300048X. Online ahead of print.ABSTRACTThis participatory action research (PAR) aimed to understand the health implications of guidelines impacting social isolation among frail community-dwelling older adults and their family and formal caregivers during the coronavirus disease (COVID-19) pandemic. Reflexive thematic analysis (RTA) of data collected from 10 policy/procedural documents revealed four themes: valuing principles, identifying problem(s), setting priorities, and making recommendations. Interviews with 31 participants from Peterborough, Ontario, also revealed ...
Source: Canadian Journal on Aging - September 18, 2023 Category: Geriatrics Authors: Ann MacLeod Justine Levesque Catherine Ward-Griffin Source Type: research
Registered Practical Nurses' Experiences of the Moral Habitability of Long-Term Care Environments during the COVID-19 Pandemic
Can J Aging. 2023 Sep 18:1-9. doi: 10.1017/S0714980823000491. Online ahead of print.ABSTRACTThe COVID-19 pandemic has had a deleterious impact on the lives of nurses who work in long-term care; however, the moral conditions of their work have been largely unexamined. The purpose of this qualitative study, therefore, was to explore registered practical nurses' (RPNs) experiences of the moral habitability of long-term care environments in Ontario, Canada during the COVID-19 pandemic. Four themes were identified: (1) Striving to meet responsibilities in a failed system; (2) bearing the moral and emotional weight of residents'...
Source: Canadian Journal on Aging - September 18, 2023 Category: Geriatrics Authors: Elizabeth Peter Shan Mohammed Priscilla Boakye Donald Rose Tieghan Killackey Source Type: research
The necessity of proactive measures from healthcare providers highlighted by delayed breast cancer diagnosis due to COVID-19: A case report
Clin Case Rep. 2023 Sep 15;11(9):e7919. doi: 10.1002/ccr3.7919. eCollection 2023 Sep.ABSTRACTKEY CLINICAL MESSAGE: During disasters, multiple factors can cause significant delays in medical visits. Regular patient monitoring, high-risk individual alerts, and telemedicine enhancements can potentially alleviate these issues and ensure timely interventions.ABSTRACT: During the COVID-19 pandemic, a Japanese woman in her 70s delayed her regular breast cancer checkup for over 2 years. During disasters, health priorities tend to decline, necessitating proactive measures from healthcare providers, such as augmenting collaboration ...
Source: Clinical Genitourinary Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Yudai Kaneda Akihiko Ozaki Mira Namba Toyoaki Sawano Masahiro Wada Hiroaki Saito Yoshiaki Kanemoto Tomohiro Kurokawa Masaharu Tsubokura Kazunoshin Tachibana Tetsuya Tanimoto Tohru Ohtake Tomozo Ejiri Hiroaki Shimmura Norio Kanzaki Source Type: research
Emergency department visits and hospital admissions for suicidal ideation, self-poisoning and self-harm among adolescents in Canada during the COVID-19 pandemic
CMAJ. 2023 Sep 18;195(36):E1221-E1230. doi: 10.1503/cmaj.220507.ABSTRACTBACKGROUND: The COVID-19 pandemic had profound effects on the mental wellbeing of adolescents. We sought to evaluate pandemic-related changes in health care use for suicidal ideation, self-poisoning and self-harm.METHODS: We obtained data from the Canadian Institute for Health Information on emergency department visits and hospital admissions from April 2015 to March 2022 among adolescents aged 10-18 years in Canada. We calculated the quarterly percentage of emergency department visits and hospital admissions for a composite outcome comprising suicidal...
Source: cmaj - September 18, 2023 Category: General Medicine Authors: Naveen Poonai Stephen B Freedman Amanda S Newton Scott Sawyer Nathalie Gaucher Samina Ali Bruce Wright Michael R Miller Ahmed Mater Eleanor Fitzpatrick Mona Jabbour Roger Zemek Mohamed Eltorki Quynh Doan Pediatric Emergency Research Canada (PERC) Network Source Type: research
Self-harm among youth during the first 28 months of the COVID-19 pandemic in Ontario, Canada: a population-based study
We reported relative differences between observed and expected monthly rates overall and by age group (10-13 yr and 14-17 yr), sex and mental health service use (new and continuing).RESULTS: In this population of about 1.3 million children and adolescents, rates of acute care visits for self-harm during the pandemic were higher than expected for emergency department visits (0.27/1000 population v. 0.21/1000 population; adjusted rate ratio [RR] 1.29, 95% confidence interval [CI] 1.19-1.39) and hospital admissions (0.74/10 000 population v. 0.43/10 000 population, adjusted RR 1.72, 95% CI 1.46-2.03). This increase was primar...
Source: cmaj - September 18, 2023 Category: General Medicine Authors: Rachel H B Mitchell Alene Toulany Hannah Chung Eyal Cohen Longdi Fu Rachel Strauss Simone N Vigod Therese A Stukel Kimberly Moran Astrid Guttmann Paul Kurdyak Azmina Artani Monica Kopec Natasha R Saunders Source Type: research
