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Infectious Disease: Pandemics
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Total 136914 results found since Jan 2013.
"It's already stressful being a foster parent": A qualitative inquiry into foster parenting stress during COVID-19
CONCLUSIONS: Findings from this study demonstrated foster parents experienced both shared and unique parenting challenges during COVID-19. Three areas for further consideration and development in practice included improving online service delivery, strengthening guidance for online parent-child visitation, and enhancing support for foster parents of children with special needs. Developing social support and self-care practices should continue to be ongoing priorities for foster parents and foster parent-serving agencies.PMID:37717544 | DOI:10.1016/j.chiabu.2023.106455
Source: Child Abuse and Neglect - September 17, 2023 Category: Child Development Authors: Erin Findley Source Type: research
Oxygen therapy in patients with intermediate-risk acute pulmonary embolism: a randomized trial
Chest. 2023 Sep 15:S0012-3692(23)05431-4. doi: 10.1016/j.chest.2023.09.007. Online ahead of print.ABSTRACTBACKGROUND: The effect of supplemental oxygen therapy in patients with intermediate-risk pulmonary embolism (PE) who do not have hypoxemia at baseline is uncertain.RESEARCH QUESTION: Does supplemental oxygen improve echocardiographic parameters in non-hypoxemic patients with intermediate-risk PE?STUDY DESIGN AND METHODS: This pilot trial randomly assigned non-hypoxemic patients with stable PE and echocardiographic right ventricle (RV) enlargement to receive anticoagulation plus supplemental oxygen for the first 48 hour...
Source: Chest - September 17, 2023 Category: Respiratory Medicine Authors: Deisy Barrios Diego Dur án Carmen Rodr íguez Jorge Mois és Ana Retegui Jos é Luis Lobo Raquel L ópez Leyre Chasco Luis Jara-Palomares Alfonso Muriel Remedios Otero-Candelera Pedro Ruiz-Artacho Manuel Monreal Behnood Bikdeli David Jim énez AIR invest Source Type: research
Regulation of SARS-CoV-2 infection and antiviral innate immunity by ubiquitination and ubiquitin-like conjugation
Biochim Biophys Acta Gene Regul Mech. 2023 Sep 15:194984. doi: 10.1016/j.bbagrm.2023.194984. Online ahead of print.ABSTRACTA global pandemic COVID-19 resulting from SARS-CoV-2 has affected a significant portion of the human population. Antiviral innate immunity is critical for controlling and eliminating the viral infection. Ubiquitination is extensively involved in antiviral signaling, and recent studies suggest that ubiquitin-like proteins (Ubls) modifications also participate in innate antiviral pathways such as RLR and cGAS-STING pathways. Notably, virus infection harnesses ubiquitination and Ubls modifications to faci...
Source: Biochimica et Biophysica Acta - September 17, 2023 Category: Biochemistry Authors: Yi Zheng Huiyu Yang Xuejing Zhang Chengjiang Gao Source Type: research
Transcriptomic Analysis in Renal Cell Carcinoma and COVID-19 patients
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):156-162. doi: 10.14715/cmb/2023.69.8.24.ABSTRACTCOVID-19 pandemic poses a heavy risk upon global public health. The disease's severity and infection rate are high, especially among cancer patients. The current research was conducted to identify the most common biological pathways and how far they are associated with COVID-19 infection and clear cell renal cell carcinoma. In the current study, the authors analyzed the differentially expressed genes from the experimental and control groups with the help of the GEO2R tool. The study analyzed the protein-protein interactions th...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Maha Abdulla Alwaili Source Type: research
Occurrence, formation, and proteins perturbation of disinfection byproducts in indoor air resulting from chlorine disinfection
This study highlights the potential secondary biological risk caused by intensive DBPs generated from chlorination and draws our attention to the potential environmental factors leading to chronic respiratory disease.PMID:37716567 | DOI:10.1016/j.chemosphere.2023.140182
Source: Chemosphere - September 16, 2023 Category: Chemistry Authors: Yangwei Xiang Huan Xu Source Type: research
Tele-Neuropsychology: From Science to Policy to Practice
CONCLUSIONS: More studies of the reliability and validity of in-home tele-np-t using randomization methodology are necessary to support inclusion of tele-np-t codes on the CMS and CPT telehealth lists, and subsequently, the integration and delivery of in-home tele-np-t services across providers and institutions. These actions are needed to maintain equitable reimbursement of in-home tele-np-t services and address the widespread disparities in healthcare access.PMID:37715508 | DOI:10.1093/arclin/acad066
Source: Archives of Clinical Neuropsychology - September 16, 2023 Category: Psychiatry & Psychology Authors: Scott A Sperling Shawn K Acheson Joshua Fox-Fuller Mary K Colvin Lana Harder C Munro Cullum John J Randolph Kirstine R Carter Patricia Espe-Pfeifer Laura H Lacritz Peter A Arnett Stephen R Gillaspy Source Type: research
COVID-19 fear, vaccination hesitancy, and vaccination status in pregnant and breastfeeding women in Turkey
This study aimed to determine the level of COVID-19 fear, vaccination, and vaccination hesitancy as well as the affecting factors in pregnant and breastfeeding women who participated in an online prenatal education in Turkey. The study, which was designed as descriptive cross-sectional, was conducted online with 360 pregnant and breastfeeding women from Istanbul. Data were collected through the Participant Information Form, Fear of COVID-19 Scale and Vaccine Hesitancy Scale in Pandemics. The rate of accepting the COVID-19 vaccine is 65.6%. The Fear of COVID-19 Scale was 16.215.54, and the Vaccine Hesitancy Scale in Pand...
Source: African Journal of Reproductive Health - September 16, 2023 Category: African Health Authors: Mukaddes T Miral Nurg ül Turgut Ay şe Güldür Z übeyde E Güloğlu Rojjin Mamuk Source Type: research
Review of the impact of the FDA's Fast Track Designation on biotechnology companies' share prices
This study examines the effect of the FDA's Fast Track Designation (FTD) on biotech company share prices. Using an event-study approach on 25 FTD announcements between June 2019 and June 2020, notable short- and long-term share price hikes were observed, with a 5-day cumulative average abnormal returns of 21.59%, 30-day at 38.34%, 1-year at 76.64% and 3-year at 111.37% against the XBI benchmark. These surges surpass prior research findings, indicating stronger investor reactions. The role of the COVID-19 pandemic as a confounder is discussed. Although the sample size is limited, the results offer valuable insights for inve...
Source: Drug Discovery Today - September 16, 2023 Category: Drugs & Pharmacology Authors: Joab Williamson Alexander James Spicer Source Type: research
Occurrence, formation, and proteins perturbation of disinfection byproducts in indoor air resulting from chlorine disinfection
This study highlights the potential secondary biological risk caused by intensive DBPs generated from chlorination and draws our attention to the potential environmental factors leading to chronic respiratory disease.PMID:37716567 | DOI:10.1016/j.chemosphere.2023.140182
Source: Chemosphere - September 16, 2023 Category: Chemistry Authors: Yangwei Xiang Huan Xu Source Type: research
Transcriptomic Analysis in Renal Cell Carcinoma and COVID-19 patients
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):156-162. doi: 10.14715/cmb/2023.69.8.24.ABSTRACTCOVID-19 pandemic poses a heavy risk upon global public health. The disease's severity and infection rate are high, especially among cancer patients. The current research was conducted to identify the most common biological pathways and how far they are associated with COVID-19 infection and clear cell renal cell carcinoma. In the current study, the authors analyzed the differentially expressed genes from the experimental and control groups with the help of the GEO2R tool. The study analyzed the protein-protein interactions th...
Source: Cancer Control - September 16, 2023 Category: Cancer & Oncology Authors: Maha Abdulla Alwaili Source Type: research
Demographic and Geographic Characterization of Excess Mortality During the COVID-19 Pandemic in Baltimore City, MD, March 2020 - March 2021
Am J Epidemiol. 2023 Sep 15:kwad186. doi: 10.1093/aje/kwad186. Online ahead of print.ABSTRACTEstimates of excess mortality can provide insight into direct and indirect impacts of the COVID-19 pandemic beyond deaths specifically attributed to COVID-19. We analyzed death certificate data from Baltimore City, Maryland from March 1, 2020 to March 31, 2021 and found that 1,725 individuals (95% confidence interval, 1,495-1,954) died in excess of what was expected from all-cause mortality trends in 2016-2019. 1,050 (61%) excess deaths were attributed to COVID-19. Observed mortality was 23-32% higher than expected among individual...
Source: Am J Epidemiol - September 16, 2023 Category: Epidemiology Authors: Kyle T Aune Kyra H Grantz Neia Prata Menezes Katherine O Robsky Emily S Gurley Melissa A Marx Darcy F Phelan-Emrick Source Type: research
Renewal equations for delayed population behaviour adaptation coupled with disease transmission dynamics: A mechanism for multiple waves of emerging infections
Math Biosci. 2023 Sep 14:109068. doi: 10.1016/j.mbs.2023.109068. Online ahead of print.ABSTRACTThere are many plausible reasons for recurrent outbreaks of emerging infectious diseases. In this paper, we develop a mathematical model to illustrate how population behavioural adaption and adaptation implementation delay, in response to the perceived infection risk, can lead to recurrent outbreak patterns. We consider the early phase of an infection outbreak when herd immunity is not reached, pathogen mutation is not considered, and seasonality is ruled out as a major contributor. We derive a transmission dynamics model coupled...
Source: Mathematical Biosciences - September 16, 2023 Category: Statistics Authors: Xue Zhang Francesca Scarabel Kumar Murty Jianhong Wu Source Type: research
Advanced bibliometric analysis on water, energy, food, and environmental nexus (WEFEN)
This article investigates research within the field of the quadruple nexus. Data from Scopus documents, with the keywords "water, energy, food, and environment" from 2011 to 2022, were processed and analyzed. Further research revealed that scientific exploration of the water-energy-food-environment relationship is rapidly expanding. The Scopus database was used to extract information about countries, institutions, highly cited publications, keywords, hot topics, and future research trends for this study. Additionally, the VOSviewer bibliometric software was employed to evaluate the scientific citations in this article. The...
Source: Environmental Science and Pollution Research International - September 16, 2023 Category: Environmental Health Authors: Armin Tayefeh Mahmoud Abdous Rahim Zahedi Alireza Aslani Mohammad Mahdi Zolfagharzadeh Source Type: research
Ethical Requirements for Human Challenge Studies: A Systematic Review of Reasons
Clin Pharmacol Ther. 2023 Sep 16. doi: 10.1002/cpt.3054. Online ahead of print.ABSTRACTHuman challenge studies (HCS) are controlled clinical trials in which participants are deliberately infected with a pathogen. Such trials are being developed for an increasing number of diseases. Partly as a result of the COVID-19 pandemic, there has been a recent ethical debate about the reasons for and against HCS in general, or rather, about the requirements that individual HCS must fulfill to be ethically acceptable. A systematic review was conducted to categorize and summarize such requirements and the reasons given for them. Ethics...
Source: Clinical Pharmacology and Therapeutics - September 16, 2023 Category: Drugs & Pharmacology Authors: Matthias Katzer Sabine Salloch Christoph Schindler Marcel Mertz Source Type: research
Demographic and Geographic Characterization of Excess Mortality During the COVID-19 Pandemic in Baltimore City, MD, March 2020 - March 2021
Am J Epidemiol. 2023 Sep 15:kwad186. doi: 10.1093/aje/kwad186. Online ahead of print.ABSTRACTEstimates of excess mortality can provide insight into direct and indirect impacts of the COVID-19 pandemic beyond deaths specifically attributed to COVID-19. We analyzed death certificate data from Baltimore City, Maryland from March 1, 2020 to March 31, 2021 and found that 1,725 individuals (95% confidence interval, 1,495-1,954) died in excess of what was expected from all-cause mortality trends in 2016-2019. 1,050 (61%) excess deaths were attributed to COVID-19. Observed mortality was 23-32% higher than expected among individual...
Source: Am J Epidemiol - September 16, 2023 Category: Epidemiology Authors: Kyle T Aune Kyra H Grantz Neia Prata Menezes Katherine O Robsky Emily S Gurley Melissa A Marx Darcy F Phelan-Emrick Source Type: research
