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Infectious Disease: Pandemics
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Total 136914 results found since Jan 2013.
Demographic and Geographic Characterization of Excess Mortality During the COVID-19 Pandemic in Baltimore City, MD, March 2020 - March 2021
Am J Epidemiol. 2023 Sep 15:kwad186. doi: 10.1093/aje/kwad186. Online ahead of print.ABSTRACTEstimates of excess mortality can provide insight into direct and indirect impacts of the COVID-19 pandemic beyond deaths specifically attributed to COVID-19. We analyzed death certificate data from Baltimore City, Maryland from March 1, 2020 to March 31, 2021 and found that 1,725 individuals (95% confidence interval, 1,495-1,954) died in excess of what was expected from all-cause mortality trends in 2016-2019. 1,050 (61%) excess deaths were attributed to COVID-19. Observed mortality was 23-32% higher than expected among individual...
Source: Am J Epidemiol - September 16, 2023 Category: Epidemiology Authors: Kyle T Aune Kyra H Grantz Neia Prata Menezes Katherine O Robsky Emily S Gurley Melissa A Marx Darcy F Phelan-Emrick Source Type: research
Review of the impact of the FDA's Fast Track Designation on biotechnology companies' share prices
This study examines the effect of the FDA's Fast Track Designation (FTD) on biotech company share prices. Using an event-study approach on 25 FTD announcements between June 2019 and June 2020, notable short- and long-term share price hikes were observed, with a 5-day cumulative average abnormal returns of 21.59%, 30-day at 38.34%, 1-year at 76.64% and 3-year at 111.37% against the XBI benchmark. These surges surpass prior research findings, indicating stronger investor reactions. The role of the COVID-19 pandemic as a confounder is discussed. Although the sample size is limited, the results offer valuable insights for inve...
Source: Drug Discovery Today - September 16, 2023 Category: Drugs & Pharmacology Authors: Joab Williamson Alexander James Spicer Source Type: research
COVID-19 fear, vaccination hesitancy, and vaccination status in pregnant and breastfeeding women in Turkey
This study aimed to determine the level of COVID-19 fear, vaccination, and vaccination hesitancy as well as the affecting factors in pregnant and breastfeeding women who participated in an online prenatal education in Turkey. The study, which was designed as descriptive cross-sectional, was conducted online with 360 pregnant and breastfeeding women from Istanbul. Data were collected through the Participant Information Form, Fear of COVID-19 Scale and Vaccine Hesitancy Scale in Pandemics. The rate of accepting the COVID-19 vaccine is 65.6%. The Fear of COVID-19 Scale was 16.215.54, and the Vaccine Hesitancy Scale in Pand...
Source: African Journal of Reproductive Health - September 16, 2023 Category: African Health Authors: Mukaddes T Miral Nurg ül Turgut Ay şe Güldür Z übeyde E Güloğlu Rojjin Mamuk Source Type: research
Tele-Neuropsychology: From Science to Policy to Practice
CONCLUSIONS: More studies of the reliability and validity of in-home tele-np-t using randomization methodology are necessary to support inclusion of tele-np-t codes on the CMS and CPT telehealth lists, and subsequently, the integration and delivery of in-home tele-np-t services across providers and institutions. These actions are needed to maintain equitable reimbursement of in-home tele-np-t services and address the widespread disparities in healthcare access.PMID:37715508 | DOI:10.1093/arclin/acad066
Source: Archives of Clinical Neuropsychology - September 16, 2023 Category: Psychiatry & Psychology Authors: Scott A Sperling Shawn K Acheson Joshua Fox-Fuller Mary K Colvin Lana Harder C Munro Cullum John J Randolph Kirstine R Carter Patricia Espe-Pfeifer Laura H Lacritz Peter A Arnett Stephen R Gillaspy Source Type: research
Transcriptomic Analysis in Renal Cell Carcinoma and COVID-19 patients
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):156-162. doi: 10.14715/cmb/2023.69.8.24.ABSTRACTCOVID-19 pandemic poses a heavy risk upon global public health. The disease's severity and infection rate are high, especially among cancer patients. The current research was conducted to identify the most common biological pathways and how far they are associated with COVID-19 infection and clear cell renal cell carcinoma. In the current study, the authors analyzed the differentially expressed genes from the experimental and control groups with the help of the GEO2R tool. The study analyzed the protein-protein interactions th...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Maha Abdulla Alwaili Source Type: research
COVID-19 fear, vaccination hesitancy, and vaccination status in pregnant and breastfeeding women in Turkey
This study aimed to determine the level of COVID-19 fear, vaccination, and vaccination hesitancy as well as the affecting factors in pregnant and breastfeeding women who participated in an online prenatal education in Turkey. The study, which was designed as descriptive cross-sectional, was conducted online with 360 pregnant and breastfeeding women from Istanbul. Data were collected through the Participant Information Form, Fear of COVID-19 Scale and Vaccine Hesitancy Scale in Pandemics. The rate of accepting the COVID-19 vaccine is 65.6%. The Fear of COVID-19 Scale was 16.215.54, and the Vaccine Hesitancy Scale in Pand...
Source: African Journal of Reproductive Health - September 16, 2023 Category: African Health Authors: Mukaddes T Miral Nurg ül Turgut Ay şe Güldür Z übeyde E Güloğlu Rojjin Mamuk Source Type: research
Demographic and Geographic Characterization of Excess Mortality During the COVID-19 Pandemic in Baltimore City, MD, March 2020 - March 2021
Am J Epidemiol. 2023 Sep 15:kwad186. doi: 10.1093/aje/kwad186. Online ahead of print.ABSTRACTEstimates of excess mortality can provide insight into direct and indirect impacts of the COVID-19 pandemic beyond deaths specifically attributed to COVID-19. We analyzed death certificate data from Baltimore City, Maryland from March 1, 2020 to March 31, 2021 and found that 1,725 individuals (95% confidence interval, 1,495-1,954) died in excess of what was expected from all-cause mortality trends in 2016-2019. 1,050 (61%) excess deaths were attributed to COVID-19. Observed mortality was 23-32% higher than expected among individual...
Source: Am J Epidemiol - September 16, 2023 Category: Epidemiology Authors: Kyle T Aune Kyra H Grantz Neia Prata Menezes Katherine O Robsky Emily S Gurley Melissa A Marx Darcy F Phelan-Emrick Source Type: research
Renewal equations for delayed population behaviour adaptation coupled with disease transmission dynamics: A mechanism for multiple waves of emerging infections
Math Biosci. 2023 Sep 14:109068. doi: 10.1016/j.mbs.2023.109068. Online ahead of print.ABSTRACTThere are many plausible reasons for recurrent outbreaks of emerging infectious diseases. In this paper, we develop a mathematical model to illustrate how population behavioural adaption and adaptation implementation delay, in response to the perceived infection risk, can lead to recurrent outbreak patterns. We consider the early phase of an infection outbreak when herd immunity is not reached, pathogen mutation is not considered, and seasonality is ruled out as a major contributor. We derive a transmission dynamics model coupled...
Source: Mathematical Biosciences - September 16, 2023 Category: Statistics Authors: Xue Zhang Francesca Scarabel Kumar Murty Jianhong Wu Source Type: research
COVID-19 fear, vaccination hesitancy, and vaccination status in pregnant and breastfeeding women in Turkey
This study aimed to determine the level of COVID-19 fear, vaccination, and vaccination hesitancy as well as the affecting factors in pregnant and breastfeeding women who participated in an online prenatal education in Turkey. The study, which was designed as descriptive cross-sectional, was conducted online with 360 pregnant and breastfeeding women from Istanbul. Data were collected through the Participant Information Form, Fear of COVID-19 Scale and Vaccine Hesitancy Scale in Pandemics. The rate of accepting the COVID-19 vaccine is 65.6%. The Fear of COVID-19 Scale was 16.215.54, and the Vaccine Hesitancy Scale in Pand...
Source: African Journal of Reproductive Health - September 16, 2023 Category: African Health Authors: Mukaddes T Miral Nurg ül Turgut Ay şe Güldür Z übeyde E Güloğlu Rojjin Mamuk Source Type: research
Renewal equations for delayed population behaviour adaptation coupled with disease transmission dynamics: A mechanism for multiple waves of emerging infections
Math Biosci. 2023 Sep 14:109068. doi: 10.1016/j.mbs.2023.109068. Online ahead of print.ABSTRACTThere are many plausible reasons for recurrent outbreaks of emerging infectious diseases. In this paper, we develop a mathematical model to illustrate how population behavioural adaption and adaptation implementation delay, in response to the perceived infection risk, can lead to recurrent outbreak patterns. We consider the early phase of an infection outbreak when herd immunity is not reached, pathogen mutation is not considered, and seasonality is ruled out as a major contributor. We derive a transmission dynamics model coupled...
Source: Mathematical Biosciences - September 16, 2023 Category: Statistics Authors: Xue Zhang Francesca Scarabel Kumar Murty Jianhong Wu Source Type: research
Ethical Requirements for Human Challenge Studies: A Systematic Review of Reasons
Clin Pharmacol Ther. 2023 Sep 16. doi: 10.1002/cpt.3054. Online ahead of print.ABSTRACTHuman challenge studies (HCS) are controlled clinical trials in which participants are deliberately infected with a pathogen. Such trials are being developed for an increasing number of diseases. Partly as a result of the COVID-19 pandemic, there has been a recent ethical debate about the reasons for and against HCS in general, or rather, about the requirements that individual HCS must fulfill to be ethically acceptable. A systematic review was conducted to categorize and summarize such requirements and the reasons given for them. Ethics...
Source: Clinical Pharmacology and Therapeutics - September 16, 2023 Category: Drugs & Pharmacology Authors: Matthias Katzer Sabine Salloch Christoph Schindler Marcel Mertz Source Type: research
COVID-19 fear, vaccination hesitancy, and vaccination status in pregnant and breastfeeding women in Turkey
This study aimed to determine the level of COVID-19 fear, vaccination, and vaccination hesitancy as well as the affecting factors in pregnant and breastfeeding women who participated in an online prenatal education in Turkey. The study, which was designed as descriptive cross-sectional, was conducted online with 360 pregnant and breastfeeding women from Istanbul. Data were collected through the Participant Information Form, Fear of COVID-19 Scale and Vaccine Hesitancy Scale in Pandemics. The rate of accepting the COVID-19 vaccine is 65.6%. The Fear of COVID-19 Scale was 16.215.54, and the Vaccine Hesitancy Scale in Pand...
Source: African Journal of Reproductive Health - September 16, 2023 Category: African Health Authors: Mukaddes T Miral Nurg ül Turgut Ay şe Güldür Z übeyde E Güloğlu Rojjin Mamuk Source Type: research
Ethical Requirements for Human Challenge Studies: A Systematic Review of Reasons
Clin Pharmacol Ther. 2023 Sep 16. doi: 10.1002/cpt.3054. Online ahead of print.ABSTRACTHuman challenge studies (HCS) are controlled clinical trials in which participants are deliberately infected with a pathogen. Such trials are being developed for an increasing number of diseases. Partly as a result of the COVID-19 pandemic, there has been a recent ethical debate about the reasons for and against HCS in general, or rather, about the requirements that individual HCS must fulfill to be ethically acceptable. A systematic review was conducted to categorize and summarize such requirements and the reasons given for them. Ethics...
Source: Clinical Pharmacology and Therapeutics - September 16, 2023 Category: Drugs & Pharmacology Authors: Matthias Katzer Sabine Salloch Christoph Schindler Marcel Mertz Source Type: research
Factors associated with depression among healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis
Psychol Med. 2023 Sep 15:1-10. doi: 10.1017/S0033291723002271. Online ahead of print.ABSTRACTThe COVID-19 pandemic has had a profound impact on the mental health of healthcare workers (HCWs). We aimed to identify the factors associated with depression among HCWs during the pandemic. We conducted literature search using eight electronic databases up to July 27 2022. Observational studies with more than 200 participants investigating correlates of depression in HCWs after COVID-19 outbreak were included. We used fixed- and random-effects models to pool odds ratios (ORs) across studies, and Cochran's chi-squared test and I 2 ...
Source: Psychological Medicine - September 15, 2023 Category: Psychiatry Authors: Haoyu Tian Tianci Qiao Jing Teng Chen Kang Jia Ke Lili Shan Mengting Li Chun Shen Yan Han Source Type: research
