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Infectious Disease: Pandemics
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Total 136914 results found since Jan 2013.
Prostaglandin E < sub > 2 < /sub > and myocarditis; friend or foe?
Biochem Pharmacol. 2023 Sep 16:115813. doi: 10.1016/j.bcp.2023.115813. Online ahead of print.ABSTRACTThis review article summarizes the role of prostaglandin E2 (PGE2) and its receptors (EP1-EP4) as it relates to the inflammatory cardiomyopathy, myocarditis. During the COVID-19 pandemic, the onset of myocarditis in a subset of patients prompted a debate on the use of nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, which act to inhibit the actions of prostaglandins. This review aims to further understanding of the role of PGE2 in the pathogenesis or protection of the myocardium in myocarditis. Inflammatory ca...
Source: Biochemical Pharmacology - September 18, 2023 Category: Drugs & Pharmacology Authors: Timothy D Bryson Pamela Harding Source Type: research
Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study
CONCLUSION: Pandemic-associated restrictions led to fewer primary care consultations and relative increases in analgesic prescribing, including strong opioids, for RMDs in the UK. Policymakers must consider the impact of these changes in future healthcare resource planning.PMID:37722859 | DOI:10.3399/BJGP.2022.0648
Source: The British Journal of General Practice - September 18, 2023 Category: Primary Care Authors: Victoria K Welsh Kayleigh J Mason James Bailey Ram Bajpai Kelvin P Jordan Christian D Mallen Claire Burton Source Type: research
General practice as a place to receive help for domestic abuse during the COVID-19 pandemic: a qualitative interview study in England and Wales
CONCLUSION: Perspectives of patients and their families affected by DVA should be prioritised in general practice service planning, including during periods of transition and change.PMID:37722856 | DOI:10.3399/BJGP.2022.0528
Source: The British Journal of General Practice - September 18, 2023 Category: Primary Care Authors: Elizabeth Emsley Caroline Coope Emma Williamson Estela Capelas Barbosa Gene Feder Eszter Szilassy Source Type: research
Impact of COVID-19 on the self-esteem, psychological and dental esthetics of dental students
CONCLUSION: The pandemic, aside from affecting the health of individuals worldwide, also badly affected the well-being, mental health, and self-esteem of the dental students. Dental aesthetics plays a crucial role in the mental wellbeing and self-esteem of the students.PMID:37718829 | DOI:10.3233/WOR-220627
Source: Work - September 18, 2023 Category: Occupational Health Authors: Firas K Alqarawi Beenish Fatima Alam Talha Nayab Sami Alshehry Badr Al-Jandan Faisal Fahim Saqib Ali Source Type: research
Prostaglandin E < sub > 2 < /sub > and myocarditis; friend or foe?
Biochem Pharmacol. 2023 Sep 16:115813. doi: 10.1016/j.bcp.2023.115813. Online ahead of print.ABSTRACTThis review article summarizes the role of prostaglandin E2 (PGE2) and its receptors (EP1-EP4) as it relates to the inflammatory cardiomyopathy, myocarditis. During the COVID-19 pandemic, the onset of myocarditis in a subset of patients prompted a debate on the use of nonsteroidal anti-inflammatory drugs (NSAIDs), like ibuprofen, which act to inhibit the actions of prostaglandins. This review aims to further understanding of the role of PGE2 in the pathogenesis or protection of the myocardium in myocarditis. Inflammatory ca...
Source: Biochemical Pharmacology - September 18, 2023 Category: Drugs & Pharmacology Authors: Timothy D Bryson Pamela Harding Source Type: research
General practice as a place to receive help for domestic abuse during the COVID-19 pandemic: a qualitative interview study in England and Wales
CONCLUSION: Perspectives of patients and their families affected by DVA should be prioritised in general practice service planning, including during periods of transition and change.PMID:37722856 | DOI:10.3399/BJGP.2022.0528
Source: The British Journal of General Practice - September 18, 2023 Category: Primary Care Authors: Elizabeth Emsley Caroline Coope Emma Williamson Estela Capelas Barbosa Gene Feder Eszter Szilassy Source Type: research
Prone Positioning for Patients With COVID-19-Induced Acute Hypoxemic Respiratory Failure: Flipping the Script
Respir Care. 2023 Oct;68(10):1449-1464. doi: 10.4187/respcare.11227.ABSTRACTDuring the COVID-19 pandemic, prone positioning (PP) emerged as a widely used supportive therapy for patients with acute hypoxemic respiratory failure caused by COVID-19 infection. In particular, awake PP (APP)-the placement of non-intubated patients in the prone position-has gained popularity and hence is detailed first herein. This review discusses recent publications on the use of PP for non-intubated and intubated subjects with COVID-19, highlighting the physiological responses, clinical outcomes, influential factors affecting treatment success...
Source: Respiratory Care - September 18, 2023 Category: Respiratory Medicine Authors: Jie Li Miguel Ibarra-Estrada Claude Gu érin Source Type: research
Treatments for COVID-19
Annu Rev Med. 2023 Sep 18. doi: 10.1146/annurev-med-052422-020316. Online ahead of print.ABSTRACTThe treatment for COVID-19 has evolved rapidly since the start of the pandemic and now consists mainly of antiviral and immunomodulatory agents. Antivirals, such as remdesivir and nirmatrelvir-ritonavir, have proved to be most useful earlier in illness (e.g., as outpatient therapy) and for less severe disease. Immunomodulatory therapy, such as dexamethasone and interleukin-6 or Janus kinase inhibitors, are most useful in severe disease or critical illness. The role of anti-SARS-CoV-2 monoclonal antibodies has diminished because...
Source: Annual Review of Medicine - September 18, 2023 Category: General Medicine Authors: Hayden S Andrews Jonathan D Herman Rajesh T Gandhi Source Type: research
Impact of COVID-19 on the self-esteem, psychological and dental esthetics of dental students
CONCLUSION: The pandemic, aside from affecting the health of individuals worldwide, also badly affected the well-being, mental health, and self-esteem of the dental students. Dental aesthetics plays a crucial role in the mental wellbeing and self-esteem of the students.PMID:37718829 | DOI:10.3233/WOR-220627
Source: Work - September 18, 2023 Category: Occupational Health Authors: Firas K Alqarawi Beenish Fatima Alam Talha Nayab Sami Alshehry Badr Al-Jandan Faisal Fahim Saqib Ali Source Type: research
Building parameters linked with indoor transmission of SARS-CoV-2
Environ Res. 2023 Sep 15:117156. doi: 10.1016/j.envres.2023.117156. Online ahead of print.ABSTRACTThe rapid spread of Coronavirus Disease (2019)(COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emphasized the importance of understanding and adapting to the indoor remediation of transmissible diseases to decrease the risk for future pandemic threats. While there were many precautions in place to hinder the spread of COVID-19, there has also been a substantial increase of new research on SARS-CoV-2 that can be utilized to further mitigate the transmission risk of this novel virus. This r...
Source: Environmental Research - September 17, 2023 Category: Environmental Health Authors: Jacqueline Horne Nicholas Dunne Nirmala Singh Md Safiuddin Navid Esmaeili Merve Erenler Ian Ho Edwin Luk Source Type: research
Oxygen therapy in patients with intermediate-risk acute pulmonary embolism: a randomized trial
Chest. 2023 Sep 15:S0012-3692(23)05431-4. doi: 10.1016/j.chest.2023.09.007. Online ahead of print.ABSTRACTBACKGROUND: The effect of supplemental oxygen therapy in patients with intermediate-risk pulmonary embolism (PE) who do not have hypoxemia at baseline is uncertain.RESEARCH QUESTION: Does supplemental oxygen improve echocardiographic parameters in non-hypoxemic patients with intermediate-risk PE?STUDY DESIGN AND METHODS: This pilot trial randomly assigned non-hypoxemic patients with stable PE and echocardiographic right ventricle (RV) enlargement to receive anticoagulation plus supplemental oxygen for the first 48 hour...
Source: Chest - September 17, 2023 Category: Respiratory Medicine Authors: Deisy Barrios Diego Dur án Carmen Rodr íguez Jorge Mois és Ana Retegui Jos é Luis Lobo Raquel L ópez Leyre Chasco Luis Jara-Palomares Alfonso Muriel Remedios Otero-Candelera Pedro Ruiz-Artacho Manuel Monreal Behnood Bikdeli David Jim énez AIR invest Source Type: research
"It's already stressful being a foster parent": A qualitative inquiry into foster parenting stress during COVID-19
CONCLUSIONS: Findings from this study demonstrated foster parents experienced both shared and unique parenting challenges during COVID-19. Three areas for further consideration and development in practice included improving online service delivery, strengthening guidance for online parent-child visitation, and enhancing support for foster parents of children with special needs. Developing social support and self-care practices should continue to be ongoing priorities for foster parents and foster parent-serving agencies.PMID:37717544 | DOI:10.1016/j.chiabu.2023.106455
Source: Child Abuse and Neglect - September 17, 2023 Category: Child Development Authors: Erin Findley Source Type: research
National Cross-Sectional Epidemiological Analysis of the Impact of Pandemic COVID-19 on Vascular Procedures in Public Health System: 521,069 procedures over 4 years
CONCLUSIONS: The reorganization of health systems led to a significant reduction in vascular procedures and decrease in financial investments. On the other hand, there was a significant increase in the number of lower limb amputations and vena cava filter placements.PMID:37717819 | DOI:10.1016/j.avsg.2023.07.103
Source: Hand Surgery - September 17, 2023 Category: Surgery Authors: Marcelo Fiorelli Alexandrino da Silva Felipe Soares Oliveira Portela Andressa Cristina Sposato Louzada Marcelo Passos Teivelis Edson Amaro Junior Nelson Wolosker Source Type: research
Regulation of SARS-CoV-2 infection and antiviral innate immunity by ubiquitination and ubiquitin-like conjugation
Biochim Biophys Acta Gene Regul Mech. 2023 Sep 15:194984. doi: 10.1016/j.bbagrm.2023.194984. Online ahead of print.ABSTRACTA global pandemic COVID-19 resulting from SARS-CoV-2 has affected a significant portion of the human population. Antiviral innate immunity is critical for controlling and eliminating the viral infection. Ubiquitination is extensively involved in antiviral signaling, and recent studies suggest that ubiquitin-like proteins (Ubls) modifications also participate in innate antiviral pathways such as RLR and cGAS-STING pathways. Notably, virus infection harnesses ubiquitination and Ubls modifications to faci...
Source: Biochimica et Biophysica Acta - September 17, 2023 Category: Biochemistry Authors: Yi Zheng Huiyu Yang Xuejing Zhang Chengjiang Gao Source Type: research
Increased nationwide use of green spaces in Norway during the COVID-19 pandemic
Environ Int. 2023 Sep 11;180:108190. doi: 10.1016/j.envint.2023.108190. Online ahead of print.ABSTRACTIn recent years, there has been growing concern about the decline in human green space use and nature-based recreation in Western countries. While some evidence suggests that the COVID-19 pandemic led to increased recreational mobility in urban green spaces, it is unclear whether the pandemic led to nationwide changes in green space use in both densely and less densely populated neighborhoods, as well as whether social inequalities in green space use were reinforced or attenuated by the pandemic. To address these questions...
Source: Environment International - September 17, 2023 Category: Environmental Health Authors: Vidar Sandsaunet Ulset Zander Venter Michal Koz ák Emma Charlott Andersson Nordb ø Tilmann von Soest Source Type: research
