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Perceived Level of Life Enjoyment and Risk of Developing Disabling Dementia: The Japan Public Health Center-Based Study
DISCUSSION: A higher level of life enjoyment was associated with a lower risk of disabling dementia, particularly in the low-medium mental stress group. This finding suggests the importance of having life enjoyment by managing mental stress for reducing risk of disabling dementia.PMID:37718836 | DOI:10.1093/geronb/gbad129
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Tomokazu Tajima Ai Ikeda Takeshi Tanigawa Hiroyasu Iso Kazumasa Yamagishi Takumi Matsumura Nobufumi Yasuda Manami Inoue Shoichiro Tsugane Norie Sawada Japan Public Health Center –Based Study Group Source Type: research
Assessing the association between probable posttraumatic stress disorder symptoms and quality of life among emergency service workers using path analysis
CONCLUSION: Active coping in response to stressful situations is important for maintaining good mental health among emergency service workers. Active coping and social support may strengthen resilience, and resilience may improve QOL. Screening for mental health and QOL should include simultaneous assessment of stress-coping, social support, and resilience. Although the findings of this cross-sectional study are important, it could not confirm a causal relationship between PTSD and QOL.PMID:37718827 | DOI:10.3233/WOR-220551
Source: Work - September 18, 2023 Category: Occupational Health Authors: Yoshikazu Noda Kenichi Asano Eiji Shimizu Yoshiyuki Hirano Source Type: research
Angiogenesis inhibitor-specific hypertension increases the risk of developing aortic dissection
Biomed Pharmacother. 2023 Sep 16;167:115504. doi: 10.1016/j.biopha.2023.115504. Online ahead of print.ABSTRACTAortic dissection is an adverse event of angiogenesis inhibitors; however, the association between the drugs and aortic dissection is unclear. Therefore, we investigated if and how angiogenesis inhibitors increase the onset of aortic dissection using pharmacologically-induced aortic dissection-prone model (LAB) mice, cultured endothelial cells, and real-world databases, which is a novel integrated research approach. Disproportionality analysis was performed and calculated using the reporting odds ratio as a risk si...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Kaito Tsujinaka Yuki Izawa-Ishizawa Koji Miyata Toshihiko Yoshioka Kohei Oomine Honoka Nishi Masateru Kondo Syuto Itokazu Tatsumi Miyata Takahiro Niimura Maki Sato Fuka Aizawa Kenta Yagi Masayuki Chuma Yoshito Zamami Mitsuhiro Goda Keisuke Ishizawa Source Type: research
The necessity of proactive measures from healthcare providers highlighted by delayed breast cancer diagnosis due to COVID-19: A case report
Clin Case Rep. 2023 Sep 15;11(9):e7919. doi: 10.1002/ccr3.7919. eCollection 2023 Sep.ABSTRACTKEY CLINICAL MESSAGE: During disasters, multiple factors can cause significant delays in medical visits. Regular patient monitoring, high-risk individual alerts, and telemedicine enhancements can potentially alleviate these issues and ensure timely interventions.ABSTRACT: During the COVID-19 pandemic, a Japanese woman in her 70s delayed her regular breast cancer checkup for over 2 years. During disasters, health priorities tend to decline, necessitating proactive measures from healthcare providers, such as augmenting collaboration ...
Source: Clinical Genitourinary Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Yudai Kaneda Akihiko Ozaki Mira Namba Toyoaki Sawano Masahiro Wada Hiroaki Saito Yoshiaki Kanemoto Tomohiro Kurokawa Masaharu Tsubokura Kazunoshin Tachibana Tetsuya Tanimoto Tohru Ohtake Tomozo Ejiri Hiroaki Shimmura Norio Kanzaki Source Type: research
Angiogenesis inhibitor-specific hypertension increases the risk of developing aortic dissection
Biomed Pharmacother. 2023 Sep 16;167:115504. doi: 10.1016/j.biopha.2023.115504. Online ahead of print.ABSTRACTAortic dissection is an adverse event of angiogenesis inhibitors; however, the association between the drugs and aortic dissection is unclear. Therefore, we investigated if and how angiogenesis inhibitors increase the onset of aortic dissection using pharmacologically-induced aortic dissection-prone model (LAB) mice, cultured endothelial cells, and real-world databases, which is a novel integrated research approach. Disproportionality analysis was performed and calculated using the reporting odds ratio as a risk si...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 18, 2023 Category: Drugs & Pharmacology Authors: Kaito Tsujinaka Yuki Izawa-Ishizawa Koji Miyata Toshihiko Yoshioka Kohei Oomine Honoka Nishi Masateru Kondo Syuto Itokazu Tatsumi Miyata Takahiro Niimura Maki Sato Fuka Aizawa Kenta Yagi Masayuki Chuma Yoshito Zamami Mitsuhiro Goda Keisuke Ishizawa Source Type: research
Assessing the association between probable posttraumatic stress disorder symptoms and quality of life among emergency service workers using path analysis
CONCLUSION: Active coping in response to stressful situations is important for maintaining good mental health among emergency service workers. Active coping and social support may strengthen resilience, and resilience may improve QOL. Screening for mental health and QOL should include simultaneous assessment of stress-coping, social support, and resilience. Although the findings of this cross-sectional study are important, it could not confirm a causal relationship between PTSD and QOL.PMID:37718827 | DOI:10.3233/WOR-220551
Source: Work - September 18, 2023 Category: Occupational Health Authors: Yoshikazu Noda Kenichi Asano Eiji Shimizu Yoshiyuki Hirano Source Type: research
The necessity of proactive measures from healthcare providers highlighted by delayed breast cancer diagnosis due to COVID-19: A case report
Clin Case Rep. 2023 Sep 15;11(9):e7919. doi: 10.1002/ccr3.7919. eCollection 2023 Sep.ABSTRACTKEY CLINICAL MESSAGE: During disasters, multiple factors can cause significant delays in medical visits. Regular patient monitoring, high-risk individual alerts, and telemedicine enhancements can potentially alleviate these issues and ensure timely interventions.ABSTRACT: During the COVID-19 pandemic, a Japanese woman in her 70s delayed her regular breast cancer checkup for over 2 years. During disasters, health priorities tend to decline, necessitating proactive measures from healthcare providers, such as augmenting collaboration ...
Source: Clinical Breast Cancer - September 18, 2023 Category: Cancer & Oncology Authors: Yudai Kaneda Akihiko Ozaki Mira Namba Toyoaki Sawano Masahiro Wada Hiroaki Saito Yoshiaki Kanemoto Tomohiro Kurokawa Masaharu Tsubokura Kazunoshin Tachibana Tetsuya Tanimoto Tohru Ohtake Tomozo Ejiri Hiroaki Shimmura Norio Kanzaki Source Type: research
Assessing the association between probable posttraumatic stress disorder symptoms and quality of life among emergency service workers using path analysis
CONCLUSION: Active coping in response to stressful situations is important for maintaining good mental health among emergency service workers. Active coping and social support may strengthen resilience, and resilience may improve QOL. Screening for mental health and QOL should include simultaneous assessment of stress-coping, social support, and resilience. Although the findings of this cross-sectional study are important, it could not confirm a causal relationship between PTSD and QOL.PMID:37718827 | DOI:10.3233/WOR-220551
Source: Work - September 18, 2023 Category: Occupational Health Authors: Yoshikazu Noda Kenichi Asano Eiji Shimizu Yoshiyuki Hirano Source Type: research
Lead exposure disrupted ileal barrier of developmental Japanese quails(Coturnix japonica): Histopathological damages, microbiota dysbiosis and immune disorder
Ecotoxicol Environ Saf. 2023 Sep 15;264:115488. doi: 10.1016/j.ecoenv.2023.115488. Online ahead of print.ABSTRACTThe gut barrier plays an essential role in maintaining homeostasis and is usually composed of a mechanical barrier, a chemical barrier, an immune barrier, and a biological barrier. However, the impacts of lead (Pb) exposure on avian gut barrier are still unclear. Therefore, the present study tried to determine the toxic effects of Pb on ileal barrier of a biological model-Japanese quail (Coturnix japonica). One-week old quails were exposed to 0, 50, 500 and 1000 ppm Pb in drinking water for 5 weeks. The results ...
Source: Ecotoxicology and Environmental Safety - September 17, 2023 Category: Environmental Health Authors: Ying Zheng Mingcun Chen Yuxin Zhang Gang Wang Hongfeng Zhao Source Type: research
Pooled Analysis of Studies Evaluating Fosnetupitant and Risk Factors for Cisplatin-Induced Nausea and Vomiting During the Extended Overall Phase
CONCLUSION: This analysis revealed that fosnetupitant could have long-acting antiemetic potency (> 120 h) and indicated the importance of antiemetic therapy at 0-120 h for CINV up to 168 h after chemotherapy.PMID:37715851 | DOI:10.1007/s12325-023-02648-1
Source: Adv Data - September 16, 2023 Category: Epidemiology Authors: Naoki Inui Yukihiro Toi Yasuto Yoneshima Masahiro Morise Akito Hata Kaoru Kubota Toshiaki Saeki Tomohide Tamura Source Type: research
Seizure-related stress and arousal responses mediate a relationship between anxiety trait and state in epilepsy
CONCLUSIONS: These findings elucidate the epilepsy-specific stress and arousal characteristics and their roles in mediating traits and state anxiety. These results may reflect the long-term clinical course and unique emotion recognition tendencies in epilepsy.PMID:37716325 | DOI:10.1016/j.yebeh.2023.109442
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Hironobu Nakamura Genichi Sugihara Keiko Hara Motoki Inaji Masahiro Noha Ichiro Takumi Masako Watanabe Hidehiko Takahashi Taketoshi Maehara Hitoshi Yamamoto Shunsuke Takagi Source Type: research
Impairment of oocyte maturation as a mechanism of decreased fecundity in Japanese medaka (Oryzias latipes) exposed to the brominated flame retardant, 1,2,5,6-tetrabromocyclooctane (TBCO)
Aquat Toxicol. 2023 Sep 11;263:106695. doi: 10.1016/j.aquatox.2023.106695. Online ahead of print.ABSTRACTInhibition of oocyte maturation is an understudied mechanism by which chemical stressors can impair fecundity of female fishes. The primary objective of the present study was to develop an assay to assess oocyte maturation disruption by chemical stressors in Japanese medaka (Oryzias latipes). First, an in vitro assay to assess maturation inducing hormone (MIH)-stimulated oocyte maturation in zebrafish was validated for use with Japanese medaka. Next, using the brominated flame retardant, 1,2,5,6-tetrabromocyclooctane (T...
Source: Aquatic Toxicology - September 16, 2023 Category: Toxicology Authors: Yamin Raza Chloe Devoy Paul D Jones Jon A Doering Steve Wiseman Source Type: research
Making sense of flavivirus non-strctural protein 1 in innate immune evasion and inducing tissue-specific damage
Virus Res. 2023 Sep 14:199222. doi: 10.1016/j.virusres.2023.199222. Online ahead of print.ABSTRACTFlaviviruses include medically important mosquito-borne pathogens, such as Zika virus (ZIKV), Japanese encephalitis virus (JEV), dengue virus (DENV) and West Nile virus (WNV), that cause hundreds of millions of infections each year. Currently, there are no approved effect therapies against mosquito-borne flaviviruses. The flaviviruses encoded nonstructural protein 1 (NS1) is a secreted glycoprotein widely involved in viral replication, immune evasion, and directly causing tissue-specific damage during flaviviruses infection. U...
Source: Cell Research - September 16, 2023 Category: Cytology Authors: Quan Zeng Jiaqi Liu Chenlin Hao Bo Zhang Honglei Zhang Source Type: research
