Filtered By:
Condition: Polyps

This page shows you your search results in order of date.

Order by Relevance | Date

Total 2492 results found since Jan 2013.

Omalizumab Treatment in Uncontrolled Asthma and CRSwNP Patients, with Previous Endoscopic Sinus Surgery, to Improve Quality of Life and Endoscopic Outcomes: a Two-Year Real-Life Study
The objective of this study is to evaluate the effect of omalizumab as an adjunct to endoscopic sinus surgery (ESS) on the treatment of CRSwNP under real-life conditions.Recent FindingsSince the introduction of omalizumab, as the first biologic agent for the treatment of diseases such as severe allergic asthma, different studies have demonstrated an effect of omalizumab on CRSwNP, with significant improvements in sinonasal symptoms and endoscopic scores. The high efficacy derived from mAb therapy and the need for ESS prior to mAb recommended by guidelines, has led to compare both therapeutic alternatives, finding discrepan...
Source: Current Allergy and Asthma Reports - September 19, 2023 Category: Allergy & Immunology Source Type: research

Management of Mechanical Nasal Obstruction Isolated or Associated to Upper Airway Inflammatory Diseases in Real Life: Use of both Subjective and Objective Criteria
AbstractPurpose of ReviewMechanical nasal obstruction (MNO) is a prevalent condition with a high impact on patient ’s quality-of-life (QoL) and socio-economic burden. The aim of this study was to determine the usefulness of both subjective and objective criteria in the appropriate management of MNO, either alone or associated to upper airway inflammatory diseases such as allergic rhinitis (AR) or chronic rhino sinusitis with nasal polyps (CRSwNP).Recent FindingsA long debate persists about the usefulness of subjective and objective methods for making decisions on the management of patients with nasal obstruction. Establi...
Source: Current Allergy and Asthma Reports - September 19, 2023 Category: Allergy & Immunology Source Type: research

Endoscopic vidian and vidian ‐branch neurectomy for refractory allergic rhinitis: A systematic review
ConclusionEVN and vidian-branch neurectomy (including SVN and PNN) are effective treatments, but the former has a higher risk of complications. Additionally, vidian-branch neurectomy with FESS is beneficial for patients with mixed CRSwNP. SVN is a potential approach for patients with coexisting AR and asthma.
Source: International Forum of Allergy and Rhinology - September 16, 2023 Category: Allergy & Immunology Authors: Xun Niu, Yuzhang Chen, Tao Zhou, Hongjun Xiao Tags: REVIEW ARTICLE Source Type: research

Type 2 biomarkers and quality of life in chronic rhinosinusitis with nasal polyps
Ann Allergy Asthma Immunol. 2023 Sep 7:S1081-1206(23)01216-4. doi: 10.1016/j.anai.2023.09.001. Online ahead of print.NO ABSTRACTPMID:37689111 | DOI:10.1016/j.anai.2023.09.001
Source: Annals of Allergy, Asthma and Immunology - September 9, 2023 Category: Allergy & Immunology Authors: Rasads Misirovs Rory Chan Brian Lipworth Source Type: research

Tezepelumab Efficacy in Patients with Severe, Uncontrolled Asthma with Comorbid Nasal Polyps in NAVIGATOR
Source: Journal of Asthma and Allergy - September 4, 2023 Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research

Sleep quality burden in chronic rhinosinusitis with nasal polyps and its modulation by Dupilumab
CONCLUSION: CRSwNP was associated with a significant impact on global sleep quality, in particular insomnia, and treatment with Dupilumab induced a rapid improvement (after one single month of treatment) in all the sleep quality parameters, suggesting that sleep disturbances should be more carefully evaluated as an additional outcome in these patients.PMID:37652235 | DOI:10.1016/j.anai.2023.08.594
Source: Annals of Allergy, Asthma and Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Sebastian Ferri Carlo Montagna Marta Casini Luca Malvezzi Francesca Pirola Elena Russo Francesca Racca Maria Rita Messina Francesca Puggioni Emanuele Nappi Giovanni Costanzo Lorenzo Del Moro Giuseppe Mercante Giuseppe Spriano Giorgio Walter Canonica Giova Source Type: research

Omalizumab Treatment in Uncontrolled Asthma and CRSwNP Patients, with Previous Endoscopic Sinus Surgery, to Improve Quality of Life and Endoscopic Outcomes: a Two-Year Real-Life Study
The objective of this study is to evaluate the effect of omalizumab as an adjunct to endoscopic sinus surgery (ESS) on the treatment of CRSwNP under real-life conditions.Recent FindingsSince the introduction of omalizumab, as the first biologic agent for the treatment of diseases such as severe allergic asthma, different studies have demonstrated an effect of omalizumab on CRSwNP, with significant improvements in sinonasal symptoms and endoscopic scores. The high efficacy derived from mAb therapy and the need for ESS prior to mAb recommended by guidelines, has led to compare both therapeutic alternatives, finding discrepan...
Source: Current Allergy and Asthma Reports - August 30, 2023 Category: Allergy & Immunology Source Type: research

Academic Interest of Allergists in Atopic Dermatitis before and after Approval of Systemic Immunomodulators
Atopic dermatitis (AD) is a common inflammatory skin disease that has traditionally been managed by dermatologists. In March 2017, the United States Food and Drugs Administration (FDA) approved the first biologic, dupilumab, for the treatment of moderate-to-severe AD.1 Dupilumab is a monoclonal antibody that targets IL-4 and IL-13, which are the leading causes of allergic inflammation in various conditions including AD, asthma, eosinophilic esophagitis, and chronic rhinosinusitis with nasal polyps.
Source: Annals of Allergy, Asthma and Immunology - August 28, 2023 Category: Allergy & Immunology Authors: Sarah Zhang, Peck Y. Ong Tags: Letters Source Type: research

Sleep quality burden in chronic rhinosinusitis with nasal polyps and its modulation by Dupilumab
Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with significant burden on patients ’ quality of life and impaired sleep quality. The most common CRSwNP endotype is characterized by type-2 inflammation, with enhanced production of interleukin (IL)-4, IL-5 and IL-13. Dupilumab is a monoclonal antibody against IL-4 receptor-alpha, which inhibits both IL-4 and IL-13 signaling, and w as recently approved for treatment of CRSwNP.
Source: Annals of Allergy, Asthma and Immunology - August 28, 2023 Category: Allergy & Immunology Authors: Sebastian Ferri, Carlo Montagna, Marta Casini, Luca Malvezzi, Francesca Pirola, Elena Russo, Francesca Racca, Maria Rita Messina, Francesca Puggioni, Emanuele Nappi, Giovanni Costanzo, Lorenzo Del Moro, Giuseppe Mercante, Giuseppe Spriano, Giorgio Walter Tags: Original Article Source Type: research

Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
Type 2 inflammation is characterized by overexpression and heightened activity of type 2 cytokines, mediators and cells that drive neuroimmune activation and sensitization to previously sub-threshold stimuli. The consequences of altered neuroimmune activity differ with tissue type and disease and include: skin inflammation, sensitization to pruritogens, and itch amplification in atopic dermatitis and prurigo nodularis; airway inflammation/hyperresponsiveness, loss of expiratory volume, airflow obstruction and increased mucus production in asthma; loss of sense of smell in chronic rhinosinusitis with nasal polyps; and dysph...
Source: Journal of Allergy and Clinical Immunology - August 25, 2023 Category: Allergy & Immunology Authors: Brian Kim, Marc E. Rothenberg, Xin Sun, Claus Bachert, David Artis, Raza Zaheer, Yamo Deniz, Paul Rowe, Sonya Cyr Source Type: research

Management of Mechanical Nasal Obstruction Isolated or Associated to Upper Airway Inflammatory Diseases in Real Life: Use of both Subjective and Objective Criteria
AbstractPurpose of ReviewMechanical nasal obstruction (MNO) is a prevalent condition with a high impact on patient ’s quality-of-life (QoL) and socio-economic burden. The aim of this study was to determine the usefulness of both subjective and objective criteria in the appropriate management of MNO, either alone or associated to upper airway inflammatory diseases such as allergic rhinitis (AR) or chronic rhino sinusitis with nasal polyps (CRSwNP).Recent FindingsA long debate persists about the usefulness of subjective and objective methods for making decisions on the management of patients with nasal obstruction. Establi...
Source: Current Allergy and Asthma Reports - August 10, 2023 Category: Allergy & Immunology Source Type: research