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The comparison of total energy and protein intake relative to estimated requirements in chronic spinal cord injury
Br J Nutr. 2023 Sep 20:1-30. doi: 10.1017/S0007114523002088. Online ahead of print.ABSTRACTIn chronic spinal cord injury (SCI), individuals experience dietary inadequacies complicated by an understudied research area. Our objectives were to assess (1) the agreement between methods of estimating energy requirement (EER) and estimated energy intake (EEI) and (2) whether dietary protein intake met SCI-specific protein guidelines. Persons with chronic SCI (n=43) completed 3-day food records to assess EEI and dietary protein intake. EER was determined with the Long and Institute of Medicine (IOM) methods and the SCI-specific Fa...
Source: The British Journal of Nutrition - September 19, 2023 Category: Nutrition Authors: Gary J Farkas Arthur S Berg Alicia Sneij David R Dolbow Ashraf S Gorgey David R Gater Source Type: research
Rural nutrition and dietetics research-Future directions
CONCLUSION: Establishing strong, collaborative place-based nutrition and dietetics research teams are necessary to combat the significant gaps in the scientific knowledge of solutions to improve nutrition in rural Australia. Further, dieticians and nutritionists who live in and understand the rural contexts are yet to be fully harnessed in research, and better engaging with these professionals will have the best chance of successfully addressing the nutrition-related disease disparity between rural and metropolitan Australia.PMID:37723938 | DOI:10.1111/ajr.13041
Source: The Australian Journal of Rural Health - September 19, 2023 Category: Rural Health Authors: Laura Alston Susan Heaney Katherine Kent Stephanie Godrich Lucy Kocanda Jaimee Herbert Tracy Schumacher Leanne J Brown Source Type: research
Correction: Microglia Sirt6 modulates the transcriptional activity of NRF2 to ameliorate high-fat diet-induced obesity
Mol Med. 2023 Sep 19;29(1):128. doi: 10.1186/s10020-023-00723-5.NO ABSTRACTPMID:37726670 | DOI:10.1186/s10020-023-00723-5
Source: Molecular Medicine - September 19, 2023 Category: Molecular Biology Authors: Xiaoxia Xiao Huiling Hu Yadi Zhong Yingjian Chen Kaijia Tang Zhisen Pan Jiawen Huang Xiaoying Yang Qi Wang Yong Gao Source Type: research
The importance of omega-3 polyunsaturated fatty acids as high-quality food in freshwater ecosystems with implications of global change
Biol Rev Camb Philos Soc. 2023 Sep 19. doi: 10.1111/brv.13017. Online ahead of print.ABSTRACTTraditionally, trophic ecology research on aquatic ecosystems has focused more on the quantity of dietary energy flow within food webs rather than food quality and its effects on organisms at various trophic levels. Recent studies emphasize that food quality is central to consumer growth and reproduction, and the importance of food quality for aquatic ecosystems has become increasingly well recognized. It is timely to synthesise these findings and identify potential future research directions. We conducted a systematic review of om...
Source: Biological Reviews of the Cambridge Philosophical Society - September 19, 2023 Category: Biology Authors: Keheng Yan Fen Guo Martin J Kainz Feilong Li Wei Gao Stuart E Bunn Yuan Zhang Source Type: research
Effects of long-term consumption of two plant-based dietary supplements on cardiovascular health and low-grade inflammation in middle-aged and elderly people: study protocol for a randomised, controlled trial
This study will provide evidence whether long-term, plant-based dietary supplementation can support cardiovascular health, anti-inflammatory processes, immunity and nutritional status in ageing. Trial registration This trial was registered at ClinicalTrials.gov (NCT04763291) on February 21, 2021.PMID:37726820 | PMC:PMC10510179 | DOI:10.1186/s41043-023-00434-x
Source: Journal of Health, Population, and Nutrition - September 19, 2023 Category: International Medicine & Public Health Authors: Melina Tsiountsioura Gerhard Cvirn Lisa Meixner-Goetz Tobias Ziegler Manfred Lamprecht Source Type: research
Selenium-dependent glutathione peroxidase 1 regulates transcription of elongase 3 in murine tissues
This study explored underlying mechanisms of GPX1 in regulating tissue fatty acid (FA) biosynthesis. GPX1 OE, KO, and wild-type (WT) mice (n = 5, male, 3-6 months old) were fed a Se-adequate diet (0.3 mg/kg) and assayed for liver and adipose tissue FA profiles and mRNA levels of key enzymes of FA biosynthesis and redox-responsive transcriptional factors (TFs). These three genotypes of mice (n = 5) were injected intraperitoneally with diquat, ebselen, and N-acetylcysteine (NAC) at 10, 50, and 50 mg/kg of body weight, respectively, and killed at 0 and 12 h after the injections to detect mRNA levels of FA elongases and desatu...
Source: Free Radical Biology and Medicine - September 19, 2023 Category: Biology Authors: Ziqiao Sun Kun Wu Chenhan Feng Xin Gen Lei Source Type: research
Postsecondary Students' Knowledge of and Adherence to the 2019 Canada's Food Guide: A Cross-sectional Pilot Survey
Conclusions: Although half of the participants correctly answered all 8 questions that assessed knowledge of the CFG, there is an opportunity for dietitians and related health professionals to improve engagement with CFG.PMID:37725514 | DOI:10.3148/cjdpr-2023-008
Source: Canadian Journal of Dietetic Practice and Research - September 19, 2023 Category: Nutrition Authors: Heather J Zhao Rosain Stennett Sharon I Kirkpatrick Russell J de Souza Source Type: research
The separation and identification of circulating small extracellular vesicles from endurance-trained, strength-trained and recreationally active men
This study examined the abundance, and a targeted metabolomic profile, of small EVs separated from the blood of endurance athletes, strength athletes and recreationally active controls at rest (∼40 h after the most recent exercise session) on two separate but identical lab visits. No differences were observed in the abundance or metabolomic profile of small EV preparations between the groups or between the lab visits within each group. Further research should determine whether the bioactive cargoes (e.g. RNA, protein and additional metabolites) carried within EVs are altered in individuals with divergent histories of exe...
Source: The Journal of Physiology - September 19, 2023 Category: Physiology Authors: Ian A J Darragh Niamh McNamee R óisín Daly Sarai Martinez Pacheco Lorraine O'Driscoll Brendan Egan Source Type: research
Osteopontin-driven T-cell accumulation and function in adipose tissue and liver promoted insulin resistance and MAFLD
CONCLUSIONS: Current findings highlight a critical role of SPP1 in the initiation of obesity-driven chronic inflammation by regulating accumulation and/or polarization of T cells. Early targeting of SPP1 could be beneficial for IR and MAFLD treatment.PMID:37724058 | DOI:10.1002/oby.23868
Source: Obesity - September 19, 2023 Category: Eating Disorders & Weight Management Authors: Fr édéric Soysouvanh D éborah Rousseau St éphanie Bonnafous Manon Bourinet Axelle Strazzulla St éphanie Patouraux Jean Machowiak Marwin A Farrugia Antonio Iannelli Albert Tran Rodolphe Anty Carmelo Luci Philippe Gual Source Type: research
High-Fat Ketogenic Diets and Ketone Monoester Supplements Differentially Affect Substrate Metabolism during Aerobic Exercise
Am J Physiol Cell Physiol. 2023 Sep 18. doi: 10.1152/ajpcell.00359.2023. Online ahead of print.ABSTRACTChronically adhering to high-fat ketogenic diets or consuming ketone monoester supplements elicits ketosis. Resulting changes in substrate metabolism appear to be drastically different between ketogenic diets and ketone supplements. Consuming a ketogenic diet increases fatty acid oxidation with concomitant decreases in endogenous carbohydrate oxidation. Increased fat oxidation eventually results in an accumulation of circulating ketone bodies, which are metabolites of fatty acids that serve as an alternative source of fue...
Source: American Journal of Physiology. Cell Physiology - September 18, 2023 Category: Cytology Authors: Lee M Margolis Stefan M Pasiakos Emily E Howard Source Type: research
Integration of palliative care in the management of oral squamous cell carcinoma
Bioinformation. 2023 Jan 31;19(1):1-4. doi: 10.6026/97320630019001. eCollection 2023.ABSTRACTOral Squamous cell Cancers (OSCC) is strongly associated with tobacco consumption. We here in present a case study of a OSCC patient who refused standard oncological care (SOC), to highlight the importance of integrating palliative care (PC) for improved patient outcomes. A 61 years male patient, with history of chewing tobacco for more than 20 years and diagnosed to have OSCC for 1.5 years presented with severe anaemia and a cauliflower-like growth (12 x 10 cm) in the left oral cavity and cheek with greenish-yellow discharge. Pus ...
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Republica Sridhar Huwait Etimad Peter Natesan Pushparaj Gauthaman Kalamegam Source Type: research
High-Fat Ketogenic Diets and Ketone Monoester Supplements Differentially Affect Substrate Metabolism during Aerobic Exercise
Am J Physiol Cell Physiol. 2023 Sep 18. doi: 10.1152/ajpcell.00359.2023. Online ahead of print.ABSTRACTChronically adhering to high-fat ketogenic diets or consuming ketone monoester supplements elicits ketosis. Resulting changes in substrate metabolism appear to be drastically different between ketogenic diets and ketone supplements. Consuming a ketogenic diet increases fatty acid oxidation with concomitant decreases in endogenous carbohydrate oxidation. Increased fat oxidation eventually results in an accumulation of circulating ketone bodies, which are metabolites of fatty acids that serve as an alternative source of fue...
Source: Am J Physiol Cell Ph... - September 18, 2023 Category: Cytology Authors: Lee M Margolis Stefan M Pasiakos Emily E Howard Source Type: research
From the inside out: understanding the gut-heart connection
Future Cardiol. 2023 Sep 18. doi: 10.2217/fca-2023-0068. Online ahead of print.ABSTRACTThe gut microbiome was first termed as 'Animalcules' by Antonie van Leeuwenhoek in the 17th century. The diverse composition and complex interactions of gut microbes are essential for good human health. They play a crucial role in inflammation, which by itself leads to the development of cardiovascular diseases. Although the mechanisms are not fully understood, it has been studied that the gut microbiota produce several bioactive metabolites impacting cardiovascular health mainly through TMAO pathway, SCFA pathway and bile acid pathway. ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Akanksha Mahajan Deepthi Bandaru Kinna Parikh Vasu Gupta Meet Patel Source Type: research
3,3-dimethyl-1-butanol and its metabolite 3,3-dimethylbutyrate ameliorate collagen-induced arthritis independent of choline trimethylamine lyase activity
Res Sq. 2023 Sep 5:rs.3.rs-3297018. doi: 10.21203/rs.3.rs-3297018/v1. Preprint.ABSTRACTPrevious studies have identified significant alterations in intestinal carnitine metabolism in mice with collagen-induced arthritis (CIA), potentially linking bacterial dysbiosis with autoimmunity. Bacterial trimethylamine (TMA) lyases metabolize dietary carnitine to TMA, which is oxidized in the liver to trimethylamine-N-oxide (TMAO). TMAO is associated with inflammatory diseases, such as atherosclerosis, whose immunologic processes mirror that of rheumatoid arthritis (RA). Therefore, we investigated the possibility of ameliorating CIA ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Sabrina Fechtner Brendan E Allen Meagan E Chriswell Widian K Jubair Charles E Robertson Jennifer N Kofonow Daniel N Frank V Michael Holers Kristine A Kuhn Source Type: research
Integration of palliative care in the management of oral squamous cell carcinoma
Bioinformation. 2023 Jan 31;19(1):1-4. doi: 10.6026/97320630019001. eCollection 2023.ABSTRACTOral Squamous cell Cancers (OSCC) is strongly associated with tobacco consumption. We here in present a case study of a OSCC patient who refused standard oncological care (SOC), to highlight the importance of integrating palliative care (PC) for improved patient outcomes. A 61 years male patient, with history of chewing tobacco for more than 20 years and diagnosed to have OSCC for 1.5 years presented with severe anaemia and a cauliflower-like growth (12 x 10 cm) in the left oral cavity and cheek with greenish-yellow discharge. Pus ...
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Republica Sridhar Huwait Etimad Peter Natesan Pushparaj Gauthaman Kalamegam Source Type: research
