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Total 101669 results found since Jan 2013.
Efficacy of a gluten-free diet in reducing the widespread pain index and symptom severity scale in patients affected by fibromyalgia
CONCLUSIONS: A GFD improved FM symptoms evaluated with WPI and SS. This was confirmed for the first time, also with a rechallenge of the GFD that followed a non-restricted gluten-containing diet.PMID:37721353 | DOI:10.4081/reumatismo.2023.1530
Source: Reumatismo - September 18, 2023 Category: Rheumatology Authors: V Bruzzese C Marrese P Scolieri J Pepe Source Type: research
High-Fat Ketogenic Diets and Ketone Monoester Supplements Differentially Affect Substrate Metabolism during Aerobic Exercise
Am J Physiol Cell Physiol. 2023 Sep 18. doi: 10.1152/ajpcell.00359.2023. Online ahead of print.ABSTRACTChronically adhering to high-fat ketogenic diets or consuming ketone monoester supplements elicits ketosis. Resulting changes in substrate metabolism appear to be drastically different between ketogenic diets and ketone supplements. Consuming a ketogenic diet increases fatty acid oxidation with concomitant decreases in endogenous carbohydrate oxidation. Increased fat oxidation eventually results in an accumulation of circulating ketone bodies, which are metabolites of fatty acids that serve as an alternative source of fue...
Source: Am J Physiol Cell Ph... - September 18, 2023 Category: Cytology Authors: Lee M Margolis Stefan M Pasiakos Emily E Howard Source Type: research
A circadian rhythm-restricted diet regulates autophagy to improve cognitive function and prolong lifespan
Biosci Trends. 2023 Sep 17. doi: 10.5582/bst.2023.01221. Online ahead of print.ABSTRACTDiet and circadian rhythms have been found to have a profound impact on health, disease, and aging. Skipping breakfast, eating late, and overeating have adverse effects on the body's metabolism and increase the risk of cardiovascular and metabolic diseases. Disturbance of circadian rhythms has been associated with increased risk of atherosclerosis, Alzheimer's disease, Parkinson's disease, and other diseases. Abnormal deposition of amyloid β (Aβ) and tau proteins in the brain and impaired synaptic function are linked to cognitive dysfu...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Xiqi Hu Jun Peng Wei Tang Ying Xia Peipei Song Source Type: research
Subacute administration of cilostazol modulates PLC- γ/PKC-α/p38/NF-kB pathway and plays vascular protective effects through eNOS activation in early stages of atherosclerosis development
This study aimed to investigate the effects of subacute administration of cilostazol on the aortas of hypercholesterolemic rats, focusing on the signaling pathways involved in these actions.MAIN METHODS: A murine model of hypercholesterolemia was employed to mimic the early stages of atherosclerosis development. Vascular reactivity assays were performed on thoracic aorta rings to assess the vascular response, as well as the non-invasive blood pressure was evaluated by plethysmography method. Pro-inflammatory markers and malondialdehyde (MDA) levels were measured to investigate the anti-inflammatory and antioxidant effects ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Stephani Correia Braz ão Gabriel Ferreira Lima Lis Jappour Autran Ana Beatriz Ara újo Mendes Beatriz Alexandre Dos Santos Dangelo Carlo Magliano Fernanda Carla Ferreira de Brito Nadia Alice Vieira Motta Source Type: research
LKB1 delays atherosclerosis by inhibiting phenotypic transformation of vascular smooth muscle cells
CONCLUSION: Our results suggested that LKB1 can delay the progression of atherosclerosis by inhibiting the phenotypic transition of VSMCs.PMID:37722454 | DOI:10.1016/j.ijcard.2023.131363
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Kaicong Chen Chunyan Zhu Qing Zhang Zhihuan Zeng Rong Chen Tudi Li Junqian Luo Zihao Zhou Rui Zeng Source Type: research
From the inside out: understanding the gut-heart connection
Future Cardiol. 2023 Sep 18. doi: 10.2217/fca-2023-0068. Online ahead of print.ABSTRACTThe gut microbiome was first termed as 'Animalcules' by Antonie van Leeuwenhoek in the 17th century. The diverse composition and complex interactions of gut microbes are essential for good human health. They play a crucial role in inflammation, which by itself leads to the development of cardiovascular diseases. Although the mechanisms are not fully understood, it has been studied that the gut microbiota produce several bioactive metabolites impacting cardiovascular health mainly through TMAO pathway, SCFA pathway and bile acid pathway. ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Akanksha Mahajan Deepthi Bandaru Kinna Parikh Vasu Gupta Meet Patel Source Type: research
3,3-dimethyl-1-butanol and its metabolite 3,3-dimethylbutyrate ameliorate collagen-induced arthritis independent of choline trimethylamine lyase activity
Res Sq. 2023 Sep 5:rs.3.rs-3297018. doi: 10.21203/rs.3.rs-3297018/v1. Preprint.ABSTRACTPrevious studies have identified significant alterations in intestinal carnitine metabolism in mice with collagen-induced arthritis (CIA), potentially linking bacterial dysbiosis with autoimmunity. Bacterial trimethylamine (TMA) lyases metabolize dietary carnitine to TMA, which is oxidized in the liver to trimethylamine-N-oxide (TMAO). TMAO is associated with inflammatory diseases, such as atherosclerosis, whose immunologic processes mirror that of rheumatoid arthritis (RA). Therefore, we investigated the possibility of ameliorating CIA ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Sabrina Fechtner Brendan E Allen Meagan E Chriswell Widian K Jubair Charles E Robertson Jennifer N Kofonow Daniel N Frank V Michael Holers Kristine A Kuhn Source Type: research
Health profile of workers from different industries in Singapore
CONCLUSION: Health issues are prevalent in the workforce and may affect work and employee safety. It is increasingly important for employees' health to be considered in risk assessments and prioritised in workplace safety and health management systems and strategies. Health promotion interventions should be targeted, and multilevel and multicomponent initiatives should be integrated with pre-existing occupational safety programmes.PMID:37721304 | DOI:10.4103/singaporemedj.SMJ-2021-414
Source: Singapore Medical Journal - September 18, 2023 Category: General Medicine Authors: Sin Eng Chia Mei Ling Tan Elise Cheok Peh Woon Ong Source Type: research
Discretionary foods and drinks in Norwegian children and adolescents' diet: Data from the national dietary survey Ungkost 3
CONCLUSIONS: Almost all 4th and 8th graders in Norway consumed discretionary foods and drinks and these products contributed to a substantial proportion of the total energy intake and limited amounts of nutrients. Those children and adolescents consuming the least discretionary foods and drinks had a higher intake of whole grains, fish and seafood, indicating healthier and more sustainable food habits.PMID:37721223 | DOI:10.1017/S1368980023001982
Source: Public Health Nutrition - September 18, 2023 Category: International Medicine & Public Health Authors: Mari Mohn Paulsen Jannicke Borch Myhre Torunn Holm Totland Lene Frost Andersen Source Type: research
Evaluation of the turkish nutrition and health studies according to the mediterranean adequacy index
CONCLUSIONS: Adherence to the MD has decreased due to the increase in the consumption of the Western-type diet in Turkey.PMID:37721220 | DOI:10.1017/S1368980023001957
Source: Public Health Nutrition - September 18, 2023 Category: International Medicine & Public Health Authors: Nazl ıcan Erdoğan Gövez Şerife Akpinar Şerife Ayten Eda K öksal Source Type: research
Dysfunctional Cori and Krebs cycle and inhibition of lactate transporters constitute a mechanism of primary non-function of fatty liver allografts
Transl Res. 2023 Sep 16:S1931-5244(23)00146-9. doi: 10.1016/j.trsl.2023.09.006. Online ahead of print.ABSTRACTOrthotopic liver transplantation (OLT) is a lifesaving procedure. However, grafts may fail due to primary non-function (PNF). In the past, we demonstrated PNFs to be mainly associated with fatty allografts, and given its unpredictable nature, the development of a disease model is urgently needed. In an effort to investigate mechanism of fatty-allograft associated PNFs, we induced fatty liver disease in donor animals by feeding rats a diet deficient in methionine and choline (MCD). We performed OLT with allografts o...
Source: Translational Research : the journal of laboratory and clinical medicine - September 18, 2023 Category: Laboratory Medicine Authors: Ulf Kulik Caroline Moesta Reinhard Spanel J ürgen Borlak Source Type: research
Moderate and high-intensity interval training protect against diabetes-induced modulation of hepatic CD86 and CD206 expression associated with the amelioration of insulin resistance and inflammation in rats
Immunobiology. 2023 Sep 13;228(6):152745. doi: 10.1016/j.imbio.2023.152745. Online ahead of print.ABSTRACTDiabetes Mellitus (DM) can damage the function of metabolic tissues, including the liver. Liver macrophages are the first responders to tissue damage or exercise. We sought to determine whether eight weeks of interval training (HIIT & MIIT) protect against diabetes-induced modulation of hepatic CD86 and CD206 expression associated with the amelioration of insulin resistance and inflammation in rats. Thirty rats were divided into six groups, including a control group, MIIT, HIIT, DM, DM + MIIT, and DM + HIIT (n = 5 ...
Source: Immunobiology - September 18, 2023 Category: Allergy & Immunology Authors: Reza Sheikh Saeid Shakerian Seyed Reza Fatemi Tabatabaei Abdolhamid Habibi Source Type: research
Nanostructured steady-state nanocarriers for nutrients preservation and delivery
Adv Food Nutr Res. 2023;106:31-93. doi: 10.1016/bs.afnr.2023.02.001. Epub 2023 Mar 21.ABSTRACTFood bioactives possess specific physiological benefits of preventing certain diet-related chronic diseases or maintain human health. However, the limitations of the bioactives are their poor stability, lower water solubility and unacceptable bioaccessibility. Structure damage or degradation is often found for the bioactives under certain environmental conditions like high temperature, strong light, extreme pH or high oxygen concentration during food processing, packaging, storage and absorption. Nanostructured steady-state nanoca...
Source: Advances in Food and Nutrition Research - September 18, 2023 Category: Nutrition Authors: Mingqian Tan Xuedi Zhang Shan Sun Guoxin Cui Source Type: research
Plant bioactive peptides for cardiovascular disease prevention
Adv Food Nutr Res. 2023;106:219-239. doi: 10.1016/bs.afnr.2023.03.005. Epub 2023 Aug 18.ABSTRACTCardiovascular disease (CVD) is a major cause of deaths in industrialized countries and a constantly growing cause of morbidity and mortality worldwide Hypercholesterolemia is one of the main risk factors for CVD progression that may be prevented by lifestyle changes, including diet. This chapter will discuss the role of peptides from plants (soybean, lupin, cowpea, hempseed, and rice bran) sources with pleotropic activity for the prevention of CVD. Overall, the bioactivity that will be mainly discussed it is the hypocholesterol...
Source: Advances in Food and Nutrition Research - September 18, 2023 Category: Nutrition Authors: Carmen Lammi Source Type: research
