Depressive symptoms are associated with clinical outcomes in heart failure with reduced ejection fraction
ConclusionsThis study confirms that elevated depressive symptoms are associated with an increased likelihood of adverse clinical outcomes in patients with HFrEF. Poor health behaviours may contribute to the adverse association of elevated depressive symptoms with the increased hazard of adverse clinical outcomes. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 8, 2024 Category: Cardiology Authors: Andrew Sherwood,
James A. Blumenthal,
Robert J. Mentz,
Gary G. Koch,
Joseph G. Rogers,
Patricia P. Chang,
Christopher Chien,
Kirkwood F. Adams Jr,
Lisa J. Rose ‐Jones,
Brian C. Jensen,
Mark Donahue,
Kristy S. Johnson,
Alan L. Hinderliter Tags: Original Article Source Type: research
Empagliflozin to prevent progressive adverse remodelling after myocardial infarction (EMPRESS ‐MI): rationale and design
ConclusionsEMPRESS-MI will assess the effect of the SGLT2 inhibitor empagliflozin on cardiac remodelling in patients with left ventricular systolic dysfunction after an acute MI. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 8, 2024 Category: Cardiology Authors: Jaclyn Carberry,
Mark C. Petrie,
Matthew M.Y. Lee,
Katriona Brooksbank,
Ross T. Campbell,
Richard Good,
Pardeep S. Jhund,
Peter Kellman,
Ninian N. Lang,
Kenneth Mangion,
Patrick B. Mark,
Alex McConnachie,
John J.V. McMurray,
Barbara Meyer,
V Tags: Study Design Source Type: research
Genetic insights into the role of cathepsins in cardiovascular diseases: a Mendelian randomization study
ConclusionsThe study highlights the causalities of cathepsin E, L2, and O on CVDs, offering insights into their roles in cardiovascular biomarkers and therapeutic targets development. Further research is required to apply these genetic findings clinically. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 8, 2024 Category: Cardiology Authors: Ruiqi Zeng,
Zhiyi Zhou,
Wanzhe Liao,
Beian Guo Tags: Original Article Source Type: research
Overexpression of zinc ‐finger protein 418 inhibits pathological cardiac remodelling after acute myocardial infarction
ConclusionsOverexpression of ZNF418 could improve cardiac function and inhibit pathological cardiac remodelling by inhibiting the MAPK signalling pathway in post-MI mice. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 7, 2024 Category: Cardiology Authors: Hongfei Jiang,
Fei Lai,
Xixing Wang,
Fanqi Meng,
Weiliang Zhu,
Shan Huang Tags: Original Article Source Type: research
Association of a device ‐based remote management heart failure pathway with outcomes: TriageHF Plus real‐world evaluation
ConclusionsThese data represent the largest real-world evaluation of a DHFP based on multi-parametric risk stratification. The TriageHF Plus clinical pathway was associated with an improvement in HF symptoms and reduced all-cause hospitalizations. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 7, 2024 Category: Cardiology Authors: Fozia Zahir Ahmed,
Camilla Sammut ‐Powell,
Glen P. Martin,
Paul Callan,
Colin Cunnington,
Matthew Kahn,
Mita Kale,
Toni Weldon,
Rachel Harwood,
Catherine Fullwood,
Bart Gerritse,
David Lanctin,
Nelson Soken,
Niall G. Campbell,
Joanne K. Ta Tags: Original Article Source Type: research
Cardiac resynchronization therapy in inotrope ‐dependent heart failure: a meta‐analysis
ConclusionsCRT appears to be a viable option for inotrope-dependent HF, with some of these patients seeming more likely to respond. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 7, 2024 Category: Cardiology Authors: Nader J. Al ‐Shakarchi,
Jamie S.Y. Ho,
Jonathan J.H. Bray,
Fabrizio D'Ascenzo,
Edward Duffy,
Jack Hewett,
Divine Adegbie,
Faizullah Khan,
Niraj S. Kumar,
Neal Patel,
Mahmood Ahmad,
Amitava Banerjee,
Ikram Haq,
Rui Providencia Tags: Original Article Source Type: research
Pulmonary artery elastance as a predictor of hospital mortality in heart failure cardiogenic shock
ConclusionsPulmonary artery elastance has been found to be the most powerful 24 h haemodynamic predictor of in-hospital death in patients with ADHF-CS. Age, 24 h PaE, and PAPi are independently associated with hospital mortality. PaE captures right ventriclar (RV) afterload mismatch and PAPi provides a metric of RV adaptation, thus their combination generates four distinct h aemodynamic phenotypes, enhancing in-hospital death risk stratification. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 7, 2024 Category: Cardiology Authors: Luca Baldetti,
Corstiaan A. den Uil,
Giorgio Fiore,
Guglielmo Gallone,
Davide Romagnolo,
Beatrice Peveri,
Lorenzo Cianfanelli,
Francesco Calvo,
Mario Gramegna,
Vittorio Pazzanese,
Stefania Sacchi,
Andr é Dias‐Frias,
Silvia Ajello,
Anna Mar Tags: Original Article Source Type: research
Associations between in ‐hospital daily protein intake and adverse clinical outcomes in older patients with heart failure
ConclusionsLower DPI during hospitalization is associated with an increased risk of mortality and HF readmission independent of non-proteogenic energy intake, and the possible optimal DPI for predicting adverse clinical outcomes is>1.12 g/kg IBW/day in older patients with HF. Caution is warranted when protein restriction therapy is administered to older patients with HF and renal dysfunction. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 6, 2024 Category: Cardiology Authors: Satoshi Katano,
Toshiyuki Yano,
Kotaro Yamano,
Ryo Numazawa,
Ryohei Nagaoka,
Suguru Honma,
Yusuke Fujisawa,
Katsuhiko Ohori,
Hidemichi Kouzu,
Hayato Kunihara,
Hiroya Fujisaki,
Masaki Katayose,
Akiyoshi Hashimoto,
Masato Furuhashi Tags: Original Article Source Type: research
Artificial intelligence ‐assisted automated heart failure detection and classification from electronic health records
ConclusionsOur study highlights the feasibility of combining keyword searches in EHR, DL automated echocardiographic interpretation, and biobank resources to identify HF subtypes. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 4, 2024 Category: Cardiology Authors: Mon Myat Oo,
Chuang Gao,
Christian Cole,
Yoran Hummel,
Magalie Guignard ‐Duff,
Emily Jefferson,
James Hare,
Adriaan A. Voors,
Rudolf A. de Boer,
Carolyn S.P. Lam,
Ify R. Mordi,
Jasper Tromp,
Chim C. Lang Tags: Original Article Source Type: research
Galectin ‐3 levels and long‐term all‐cause mortality and hospitalization in heart failure patients: a meta‐analysis
ConclusionsHigher circulating galectin-3 levels after hospitalization of HF patients are linearly and positively associated with the risk of long-term ACM and ACM/HFR. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 3, 2024 Category: Cardiology Authors: Wenke Cheng,
Rosolowski Maciej,
Holger Thiele,
Petra B üttner Tags: Original Article Source Type: research
Hyperlactataemia is a marker of reduced exercise capacity in heart failure with preserved ejection fraction
ConclusionsHFpEF is associated with reduced exercise capacity secondary to both central and peripheral factors that alter oxygen utilization. This results in hyperlactataemia. In HFpEF, plasma lactate responses to exercise may be a marker of haemodynamic and cardiometabolic derangements and represent an important target for future potential therapies. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 3, 2024 Category: Cardiology Authors: Emilia Nan Tie,
Emil Wolsk,
Shane Nanayakkara,
Donna Vizi,
Justin Mariani,
Jacob Eifer Moller,
Christian Hassager,
Finn Gustafsson,
David M. Kaye Tags: Original Article Source Type: research
Association between biomarkers of zinc and copper status and heart failure: a meta ‐analysis
ConclusionsThis meta-analysis demonstrates that patients with HF have lower serum zinc and higher copper concentrations compared with healthy subjects. However, the potential of zinc supplementation as a therapy for HF should be approached with caution. The heterogeneity among the included studies was found to be high. It is recommended that further well-designed large sample studies be conducted to validate these findings. (Source: ESC Heart Failure)
Source: ESC Heart Failure - May 2, 2024 Category: Cardiology Authors: Ruixin Liu,
Jiali Yao,
Kexian Chen,
Wei Peng Tags: Original Article Source Type: research
Precision cardiac monitoring: algorithmic real ‐time assessment of right ventricular function in pulmonary hypertension
(Source: ESC Heart Failure)
Source: ESC Heart Failure - May 1, 2024 Category: Cardiology Authors: Nils Kremer,
Felix Glocker,
Simon Sch äfer,
Zvonimir Rako,
Athiththan Yogeswaran,
Werner Seeger,
Hans‐Bernd Hopf,
Khodr Tello Tags: Letter to the Editor Source Type: research
Relationship of interleukin ‐16 with different phenogroups in acute heart failure with preserved ejection fraction
ConclusionsOur results indicated that the serum IL-16 level had a significant association with indices that reflect the pathophysiology and prognosis of HFpEF in a specific phenogroup in acute HFpEF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 30, 2024 Category: Cardiology Authors: Shunsuke Tamaki,
Yohei Sotomi,
Yoshiyuki Nagai,
Ryu Shutta,
Daisaku Masuda,
Nobuhiko Makino,
Shizuya Yamashita,
Masahiro Seo,
Takahisa Yamada,
Akito Nakagawa,
Yoshio Yasumura,
Yusuke Nakagawa,
Masamichi Yano,
Takaharu Hayashi,
Shungo Hikoso, Tags: Original Article Source Type: research
Evaluating haemodynamic changes: vericiguat in patients with heart failure with reduced ejection fraction
ConclusionsThe consistent reduction in PAWP underscores the well-tolerated nature of vericiguat and its potential to enhance cardiac performance in patients with HFrEF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 30, 2024 Category: Cardiology Authors: Hideaki Suzuki,
Takumi Inoue,
Yousuke Terui,
Kouki Takeuchi,
Kai Susukita,
Marina Arai,
Haruka Sato,
Taijyu Satoh,
Saori Yamamoto,
Nobuhiro Yaoita,
Shunsuke Tatebe,
Hideka Hayashi,
Kotaro Nochioka,
Hiroyuki Takahama,
Satoshi Yasuda Tags: Short Communication Source Type: research
