ECMO for drug ‐refractory electrical storm without a reversible trigger: a retrospective multicentric observational study
ConclusionsVA-ECMO bridged drug-refractory ES without a reversible trigger with a high success rate. This required prolonged hospital stays and coordination between the ECMO centre, the electrophysiology laboratory, and the heart transplant programme. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 12, 2024 Category: Cardiology Authors: Isabel Dur ães‐Campos, Catarina Costa, Ana Rita Ferreira, Carla Basílio, Pau Torrella, Aida Neves, Ana Margarida Lebreiro, Gonçalo Pestana, Luís Adão, José Pinheiro‐Torres, Miguel Solla‐Buceta, Jordi Riera, Juan Ignacio Chico‐Car Tags: Original Article Source Type: research

Comment on: “A novel ‘shunt fraction’ method to derive native cardiac output during liberation from central VA ECMO” by Lim, HS
(Source: ESC Heart Failure)
Source: ESC Heart Failure - April 12, 2024 Category: Cardiology Authors: Kaspar F. Bachmann, Matthias Haenggi, Stephan M. Jakob, Jukka Takala, Luciano Gattinoni, David Berger Tags: Letter to the Editor Source Type: research

Paradox of disproportionate atrial functional mitral regurgitation and survival after transcatheter edge ‐to‐edge repair
ConclusionsThis analysis introduces the MR proportionality concept in aFMR patients and its potential prognostic value. Paradoxically, disproportionate MR in aFMR was linked to a 1.35-fold increase in 2-year mortality post-M-TEER, emphasizing the importance of accurate preprocedural FMR characterization. Our findings in patients with disproportionate MR indicate that a high degree of aFMR with high regurgitant volumes may lead to aggravated symptoms, which is a known contributor to increased mortality following M-TEER. These results underline the need for further research into the pathophysiology of aFMR to inform potentia...
Source: ESC Heart Failure - April 11, 2024 Category: Cardiology Authors: Philipp M. Doldi, Lukas Stolz, Mohammad Kassar, Daniel Kalbacher, Anna Sonia Petronio, Christian Butter, Ralph Stephan von Bardeleben, Christos Iliadis, Paul Grayburn, J örg Hausleiter Tags: Short Communication Source Type: research

Hypocapnia is associated with increased in ‐hospital mortality and 1 year mortality in acute heart failure patients
ConclusionsIn AHF patients, hypocapnia within 24  h after admission to the ICU was associated with increased in-hospital mortality and 1 year mortality. However, the increase in 1 year mortality may be influenced by hospitalization mortality. Hypercapnia was associated with increased in-hospital mortality. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 11, 2024 Category: Cardiology Authors: Lei Zhang, Yiwu Sun, Xin Sui, Jian Zhang, Jingshun Zhao, Runfeng Zhou, Wenjia Xu, Chengke Yin, Zhaoyi He, Yufei Sun, Chang Liu, Ailing Song, Fei Han Tags: Original Article Source Type: research

Estimated pulse wave velocity and risk of new ‐onset heart failure
ConclusionsePWV was an independent predictor for new-onset heart failure. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 10, 2024 Category: Cardiology Authors: Chunpeng Ji, Guodong Wang, Zhe Huang, Chenrui Zhu, Yan Liu Tags: Original Article Source Type: research

The peptide neuromedin U (NMU) is elevated in NYHA II and III heart failure
ConclusionsNMU is elevated in serum from stage II and III heart failure patients, supporting data from our pre-heart failure animal model; however, further study is needed to determine whether NMU is a reliable biomarker for pre-heart failure. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 6, 2024 Category: Cardiology Authors: Vincent Healy, Therese Ruane O'Hora, Farouk Markos Tags: Original Article Source Type: research

Association between pulmonary artery pulsatility and mortality after implantation of left ventricular assist device
ConclusionsPreoperative PAPi  <  2.84 was associated with a higher risk of early mortality after LVAD implantation without impacting 2 year outcomes among survivors. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 6, 2024 Category: Cardiology Authors: Ali Akamkam, Vincent Galand, Marie Jungling, Cl ément Delmas, Camille Dambrin, Mathieu Pernot, Michel Kindo, Philippe Gaudard, Philippe Rouviere, Thomas Senage, Olivier Chavanon, Marylou Para, Vlad Gariboldi, Matteo Pozzi, Pierre‐Yves Lit Tags: Original Article Source Type: research

Achieved dose and treatment discontinuation of candesartan in men and women with chronic heart failure: data from CHARM
ConclusionsIn a randomized clinical trial in patients with HFrEF, men and women achieved similar doses of candesartan. Primary event rates and treatment-related discontinuation due to adverse events were also similar between men and women. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 6, 2024 Category: Cardiology Authors: Hailun Qin, Pooja Dewan, Bernadet T. Santema, Jozine M. ter Maaten, Karl Swedberg, John J. V. McMurray, Adriaan A. Voors Tags: Original Article Source Type: research

Non ‐invasively assessed haemodynamics in patients with high flow arteriovenous fistula and high output cardiac failure
(Source: ESC Heart Failure)
Source: ESC Heart Failure - April 5, 2024 Category: Cardiology Authors: Krist ína Burýšková Salajová, Jan Malík, Anna Valeriánová Tags: Letter to the Editor Source Type: research

Care ‐seeking delay of patients with heart failure in China: a mixed‐method study
ConclusionsCare-seeking delay among patients with HF needs attention in China. The duration of care-seeking delay of patients with HF was influenced by the dyspnoea symptom burden, the oedema symptom burden, and depression status, as well as the COVID-19 pandemic, level of support from medical system, and the symptom management abilities of the caregivers. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 3, 2024 Category: Cardiology Authors: Mengqi Xu, Tiantian Ruan, Xiaoli Huang, Beibei Han, Yingqi Li, Yuan Ding, Lingyan Zhu Tags: Original Article Source Type: research

Impact of coronary microvascular dysfunction in heart failure with preserved ejection fraction: a meta ‐analysis
ConclusionsCMD is present in little more than half of the patients with HFpEF and is associated with echocardiographic evidence of more severe diastolic dysfunction and a higher prevalence of AF, doubling the risk of death or HF hospitalization. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 29, 2024 Category: Cardiology Authors: Domenico D'Amario, Renzo Laborante, Emiliano Bianchini, Giuseppe Ciliberti, Donato Antonio Paglianiti, Mattia Galli, Attilio Restivo, Davide Stolfo, Rocco Vergallo, Giuseppe M.C. Rosano, Filippo Crea, Carolyn S.P. Lam, Lars H. Lund, Marco Met Tags: Original Article Source Type: research

Twelve ‐year trends in unprotected left main coronary artery occlusion: insights from a real‐world multicentre study
ConclusionsIn our real-world population, despite the progressive use of newer drugs and more advanced devices over time, patients with unprotected LMCA occlusion/subtotal occlusion remain a subpopulation with poor prognosis. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 29, 2024 Category: Cardiology Authors: Andr é Alexandre, Andreia Campinas, Bruno Brochado, Marta Braga, David Sá‐Couto, Mariana Santos, Diana Ribeiro, Mariana Brandão, Marisa Passos Silva, Gustavo Pires de Morais, João Calvão, João Carlos Silva, Raquel Baggen‐Santos, And Tags: Original Article Source Type: research

Prognostic impact of frailty based on a comprehensive frailty assessment in patients with heart failure
ConclusionsThe KCL is a useful tool for risk stratification of adverse outcomes in patients with AHF. Functional declines in psycho-emotional domains including cognitive function and depressed mood contribute to adverse outcomes. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 29, 2024 Category: Cardiology Authors: Tomoyuki Hamada, Toru Kubo, Kazuya Kawai, Yoko Nakaoka, Toshikazu Yabe, Takashi Furuno, Eisuke Yamada, Hiroaki Kitaoka, On behalf of Kochi YOSACOI study Tags: Original Article Source Type: research

Intravenous iron and SGLT2 inhibitors in iron ‐deficient patients with heart failure and reduced ejection fraction
ConclusionsIn the IRONMAN trial, there was a trend to a greater increase in haemoglobin with ferric derisomaltose in iron-deficient patients taking an SGLT2 inhibitor at baseline, as compared with those not taking one. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 29, 2024 Category: Cardiology Authors: Kieran F. Docherty, John J.V. McMurray, Paul R. Kalra, John G.F. Cleland, Ninian N. Lang, Mark C. Petrie, Michele Robertson, Ian Ford Tags: Original Article Source Type: research

Increased interleukin ‐6 is associated with higher risk of heart failure in people with type 2 diabetes
ConclusionsHigher IL-6 levels are associated with the development of HF in persons with T2D. Further research should determine whether IL-6-lowering interventions could prevent the development of HF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 29, 2024 Category: Cardiology Authors: Sharon Remmelzwaal, Stanley M.H. Yeung, Marieke T. Blom, Martin H. de Borst, Petra J.M. Elders, Joline W.J. Beulens Tags: Short Communication Source Type: research