Prognostic impact of heart failure admission in survivors of acute myocardial infarction
ConclusionsUtilizing real-world data of the contemporary percutaneous coronary intervention era from the Japan Acute Myocardial Infarction Registry database, this study demonstrates that the heart failure admission of AMI survivors was significantly associated with higher all-cause mortality rates. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 30, 2024 Category: Cardiology Authors: Satoshi Takeuchi, Satoshi Honda, Kensaku Nishihira, Sunao Kojima, Misa Takegami, Yasuhide Asaumi, Mike Saji, Jun Yamashita, Kiyoshi Hibi, Jun Takahashi, Yasuhiko Sakata, Morimasa Takayama, Tetsuya Sumiyoshi, Hisao Ogawa, Kazuo Kimura, Satos Tags: Original Article Source Type: research

Efficacy of catheter ablation for atrial fibrillation in heart failure: a meta ‐analysis of randomized controlled trials
AbstractThe study aims to evaluate whether rhythm control by catheter ablation is superior to medical therapy for the patients with atrial fibrillation (AF) and heart failure (HF). The literatures were searched by using PubMed, Cochrane Library, Embase, and Web of Science databases up to 12 October 2023. The randomized controlled trials (RCTs) comparing rhythm control using catheter ablation vs. medical therapy in AF patients with HF were pooled. The primary outcomes included all-cause mortality, HF re-hospitalization, and stroke, and the secondary outcomes included left ventricular ejection fraction (LVEF), atrial tachyar...
Source: ESC Heart Failure - April 26, 2024 Category: Cardiology Authors: Zhongyin Zhang, Yan Zheng, Wenxiu He, Jiahe Wei, Pengzhan Li, Guoqiang Zhong, Zhiyuan Jiang Tags: Review Source Type: research

Letter to the editor regarding ‘Autopsy findings in cases of fatal COVID‐19 vaccine‐induced myocarditis’
(Source: ESC Heart Failure)
Source: ESC Heart Failure - April 25, 2024 Category: Cardiology Authors: Hannah Van Wyk, Mia Q. Zhu, Danielle R. Stone, Awnish Kumar Singh, Sarah Bassiouni Tags: Letter to the Editor Source Type: research

Heart failure: the grim reaper of the cardio ‐renal‐metabolic triad
ConclusionsIn a cohort of CKD patients, having HF contributes substantially to increased mortality and the risk of MACE, and these patients are less likely to start KRT. These findings highlight the urgent need for targeted therapeutic strategies and management plans for CKD patients, particularly those with concurrent HF, to enhance patient prognosis. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 25, 2024 Category: Cardiology Authors: Joakim Österman, Ehab Al‐Sodany, Ida Haugen Löfman, Peter Barany, Marie Evans Tags: Original Article Source Type: research

Cardiac sympathetic nerve activity trends after renal denervation in heart failure with preserved ejection fraction
AbstractThis case report describes the application of ultrasound renal denervation (uRDN) using the Paradise System in a patient with heart failure with preserved ejection fraction. Initially, the cardiac sympathetic nerve activity of the patient exhibited a late heart/mediastinum (H/M) ratio of 2.00 and a washout rate of 66.0% by cardiac iodine-123 metaiodobenzylguanidine (123I-MIBG) scintigraphy. Subsequently, the patient underwent transfemoral uRDN targeting the left, right upper, and right lower renal arteries. At the 6  month follow-up, no significant change was observed in123I-MIBG findings; however, the estimated s...
Source: ESC Heart Failure - April 25, 2024 Category: Cardiology Authors: Tatsuya Shiraki, Hiroya Mizuno, Takuya Kishi, Masanori Asakura, Hidetsugu Asanoi, Yoshio Yasumura, Yasushi Sakata Tags: Case Report Source Type: research

Identification of common mechanisms and biomarkers of atrial fibrillation and heart failure based on machine learning
ConclusionsWe identified four biological markers that are highly correlated with AF and HF, namely,GLUL,NCF2,S100A12, andSRGN. Our findings provide theoretical basis for the clinical diagnosis and treatment of AF and HF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 24, 2024 Category: Cardiology Authors: Zhijun Zhang, Jianying Ding, Xiaolong Mi, Yuanyuan Lin, Xinjian Li, Jun Lian, Jinwen Liu, Lijuan Qu, Bingye Zhao, Xuewen Li Tags: Original Article Source Type: research

Apixaban in bridge to transplant and destination LVAD ‐ rationale and study design: the ApixiVAD trial
ConclusionsA positive outcome in the ApixiVAD study would provide the basis for future, larger, pivotal anticoagulation trials in LVAD patients. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 23, 2024 Category: Cardiology Authors: Bruno Schnegg, Ricardo Deveza, Christopher Hayward Tags: Study Design Source Type: research

The effect of sodium ‐glucose co‐transporter 2 inhibitors on outcomes after cardiac resynchronization therapy
ConclusionsWe observed an improvement in mortality in patients undergoing CRT prescribed SGLT2i compared with those not prescribed SGLT2i, despite similar degrees of reverse remodelling. The authors recommend starting SGLT2i prior to CRT implantation, where it does not delay implantation. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 23, 2024 Category: Cardiology Authors: Jonathan J.H. Bray, Marco Coronelli, Sam G.C. Scott, John A. Henry, Liam S. Couch, Mahmood Ahmad, Julian Ormerod, James Gamble, Timothy R. Betts, Andrew Lewis, Oliver J. Rider, Peregrine G. Green, Neil Herring Tags: Original Article Source Type: research

Haemodynamic implications of VA ‐ECMO vs. VA‐ECMO plus Impella CP for cardiogenic shock in a large animal model
ConclusionsIn a porcine model of CS, we found lower PVA, with the ECMELLA configuration compared with VA-ECMO, indicating better cardiac energetics without compromising systemic perfusion. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 23, 2024 Category: Cardiology Authors: Peter H. Frederiksen, Louise Linde, Emilie Gregers, Nanna L.J. Udesen, Ole K. Helgestad, Ann Banke, Jordi S. Dahl, Lisette O. Jensen, Jens F. Lassen, Amalie L. Povlsen, Jeppe P. Larsen, Henrik Schmidt, Hanne B. Ravn, Jacob E. M øller Tags: Original Article Source Type: research

Prognostic value of growth differentiation factor ‐15 in heart failure among whole ejection fraction phenotypes
ConclusionsGDF-15 is identified as an independent risk factor for adverse outcomes in HF patients across the entire EF spectrum in the context of CHD. Integrating GDF-15 into the MAGGIC risk score-based model enhances its prognostic capability for adverse outcomes in the general HF population. This incremental prognostic effect was observed specifically in the HFpEF subgroup and not in other subgroups. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 20, 2024 Category: Cardiology Authors: Lyu Lyu, Juan Xu, Cui Xv, Hunan Xiao, Zhenzhen Liu, Yanru He, Weiyang Gao, Benchuan Hao, Hongbin Liu Tags: Original Article Source Type: research

Treatment patterns of patients with worsening heart failure with reduced ejection fraction
ConclusionsMajor gaps in use of GDMT, particularly combination therapy, remain among US HFrEF patients. These gaps persist during longitudinal follow-up and are particularly large among patients with recent WHFE. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 19, 2024 Category: Cardiology Authors: Stephen J. Greene, Hanna K. Gaggin, Mo Zhou, Lori D. Bash, Dominik Lautsch, Laurence Djatche, Yan Song, James Signorovitch, Andra S. Stevenson, Robert O. Blaustein, Javed Butler Tags: Original Article Source Type: research

Circulating miRNA in functional tricuspid regurgitation. Unveiling novel links to heart failure: A pilot study
ConclusionsCirculating miRNAs are novel diagnostic and prognostic biomarkers in severe FTR. The quantification of miR-186-5p, miR-30e-5p, and miR-152-3p held strong diagnostic value, and the quantification of miR-15a-5p and miR-92a-3p are independently associated with outcomes. The recognition of specific miRNAs offers a novel perspective for TR evaluation. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 19, 2024 Category: Cardiology Authors: Rocio Hinojar, Rafael Moreno ‐Gómez‐Toledano, Elisa Conde, Ariana Gonzalez‐Gomez, Ana García‐Martin, Paz González‐Portilla, Covadonga Fernández‐Golfín, Maria Laura García‐Bermejo, Carlos Zaragoza, Jose Luis Zamorano Tags: Original Article Source Type: research

Reply to: “CardioMEMS in HF patients: study confirms benefit in costs and QALYs, but does not measure QALYs”
(Source: ESC Heart Failure)
Source: ESC Heart Failure - April 19, 2024 Category: Cardiology Authors: Pau Codina, Francesc L ópez‐Seguí, Antoni Bayés‐Genís Tags: Reply Source Type: research

Representativeness of the PIONEER ‐HF and PARAGLIDE‐HF in patients hospitalized with acute heart failure
ConclusionsUsing trial criteria, only 31.3% of AHF patients were eligible for sacubitril –valsartan. Yet, non-eligible patients demonstrated similar outcomes to eligible patients, indicating a need for further evaluation of sacubitril–valsartan benefits in non-eligible AHF patients. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 19, 2024 Category: Cardiology Authors: Dong ‐Yi Chen, Chun‐Chi Chen, Cheng‐Hung Lee, Chi‐Nan Tseng, Shao‐Wei Chen, Shang‐Hung Chang, Tien‐Hsing Chen, Pao‐Hsien Chu, I‐Chang Hsieh, Ming‐Shien Wen, Ming‐Lung Tsai, Ming‐Jer Hsieh Tags: Original Article Source Type: research

Exercise limitation in hypertrophic cardiomyopathy: combined stress echocardiography and cardiopulmonary exercise test
ConclusionsBoth central and peripheral cardiovascular limitations are involved in exercise intolerance in HCM. Diastolic dysfunction seems to be the main driver for this limitation. (Source: ESC Heart Failure)
Source: ESC Heart Failure - April 19, 2024 Category: Cardiology Authors: Yonatan Erez, Eihab Ghantous, Aviel Shetrit, Ryan S. Zamanzadeh, David Zahler, Yoav Granot, Orly Ran Sapir, Michal Laufer Perl, Shmuel Banai, Yan Topilsky, Ofer Havakuk Tags: Original Article Source Type: research