Systemic vascular resistance predicts high ‐output cardiac failure in patients with high‐flow arteriovenous fistula
ConclusionsIn patients with high-flow AV access, low eSVR values obtained through non-invasive Doppler echocardiography were associated with a high rate of HOCF hospitalizations. Therefore, routine eSVR screening in these patients might expedite the diagnosis of HOCF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 27, 2023 Category: Cardiology Authors: Dan ‐Ying Lee,
Ting Chen,
Wei‐Chieh Huang,
Ruey‐Hsing Chou,
Cheng‐Hsueh Wu,
Chih‐Yu Yang,
Chiu‐Yang Lee,
Chih‐Ching Lin,
Der‐Cherng Tarng Tags: Original Article Source Type: research
Dapagliflozin treatment and cardiovascular outcome in RBP4/TTRVal30Met (transthyretin cardiac amyloidosis) mice
ConclusionsDapagliflozin did not improve cardiovascular prognosis including the progression of heart failure, cardiac inflammation, and pathological changes in ATTR-CA mice compared with placebo. The results of this study were not in support of dapagliflozin's therapeutic effects for ATTR-CA. More pre-clinical and clinical researches to validate these findings and demonstrate the underlying mechanisms are still required. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 26, 2023 Category: Cardiology Authors: Zonglin Li,
Fang Lv,
Xin Wen,
Chengcheng Guo,
Li Li,
Xiaoling Cai,
Chu Lin,
Mengqing Zhang,
Wenjia Yang,
Linong Ji Tags: Original Article Source Type: research
Cavin ‐2 promotes fibroblast‐to‐myofibroblast trans‐differentiation and aggravates cardiac fibrosis
ConclusionsCavin-2 loss suppressed fibroblast trans-differentiation into myofibroblasts through the TGF- β/Smad signalling. The loss of Cavin-2 in cardiac fibroblasts suppresses cardiac fibrosis and may maintain cardiac function. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 24, 2023 Category: Cardiology Authors: Yusuke Higuchi,
Takehiro Ogata,
Naohiko Nakanishi,
Masahiro Nishi,
Yumika Tsuji,
Shinya Tomita,
Simon J. Conway,
Satoaki Matoba Tags: Original Article Source Type: research
Cardiac reverse remodelling by imaging parameters with recent changes to guideline medical therapy in heart failure
AbstractRecently established heart failure therapies, including sodium glucose co-transporter 2 inhibitors, angiotensin-neprilysin inhibitors, and cardiac resynchronization therapy, have led to both clinical and structural improvements. Reverse remodelling describes the structural and functional responses to therapy and has been shown to correlate with patients' clinical response, acting as a biomarker for treatment success. The introduction of these new therapeutic agents in addition to advances in non-invasive cardiac imaging has led to an expansion in the evaluation and the validation of cardiac reverse remodelling. Met...
Source: ESC Heart Failure - October 24, 2023 Category: Cardiology Authors: Matthew Kodsi,
David Makarious,
Gary C.H. Gan,
Preeti Choudhary,
Liza Thomas Tags: Review Source Type: research
MicroRNA ‐30d and ‐483‐3p for bi‐ventricular remodelling and miR‐126‐3p for pulmonary hypertension in advanced heart failure
ConclusionsIn patients with DCM, few miRNAs are co-expressed in serum and tissue: They are related to LV remodelling (miR-30d), post-capillary pulmonary artery pressure (miR-126-3p), and right ventricular remodelling/filling pressures (miR-483-3p). Further studies are needed to confirm their role in diagnosis, prognosis or as therapeutic targets in heart failure with reduced ejection fraction. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 22, 2023 Category: Cardiology Authors: Alessia Gallo,
Valentina Agnese,
Sergio Sciacca,
Cesare Scardulla,
Manlio Cipriani,
Michele Pilato,
Jae K. Oh,
Salvatore Pasta,
Joseph Maalouf,
Pier Giulio Conaldi,
Diego Bellavia Tags: Original Article Source Type: research
Cushing's syndrome presenting as non ‐atherosclerotic myocardial infarction and heart failure
AbstractCushing's syndrome is a rare cause of myocardial infarction and heart failure. Herein, we report a female patient who presented acute myocardial infarction and heart failure with reduced ejection fraction. The patient was found to have hypercortisolism secondary to adrenocortical adenoma and responded well to therapy. This case underlines the effects of hypercortisolism on the cardiovascular system. The clinical presentation of this patient is unique because non-atherosclerotic myocardial infarction is rarely reported in Cushing's syndrome patients. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 19, 2023 Category: Cardiology Authors: Yanming Li,
Songqing He,
Jing Feng,
Sai Ma,
Lei Wang Tags: Case Report Source Type: research
D ‐dimer, C‐reactive protein and matrix metalloproteinase 9 for prediction of type A aortic dissection patient survival
ConclusionsCombined measurement of CRP,d-dimer, and MMP9 is associated with 1 year of survival in patients with ATAAD. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 18, 2023 Category: Cardiology Authors: Minjie Huang,
Yujie Lian,
Zhongyan Zeng,
Jiahong Li Tags: Original Article Source Type: research
Role of ejection fraction in patients at risk for advanced heart failure: insights from the HELP ‐HF registry
ConclusionsAmong patients with HF and at least one ‘I NEED HELP’ marker for advanced HF, left ventricular EF is still of prognostic value. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 17, 2023 Category: Cardiology Authors: Matteo Pagnesi,
Carlo Mario Lombardi,
Chiara Tedino,
Mauro Chiarito,
Davide Stolfo,
Luca Baldetti,
Marianna Adamo,
Filippo Cal ì,
Riccardo Maria Inciardi,
Daniela Tomasoni,
Ferdinando Loiacono,
Marta Maccallini,
Alessandro Villaschi,
Gaia Ga Tags: Original Article Source Type: research
International Physical Activity Questionnaire Short Form and accelerometer ‐assessed physical activity: concurrent validity using six cut‐points in HF patients
ConclusionsModerate to vigorous PA measures using IPAQ-SF and accelerometers are not equivalent, and we do not encourage researchers to use IPAQ-SF alone when assessing PA in HF patients. Moreover, applying personalized collection and processing criteria is important when assessing PA in HF patients. We recommend following the 24 h protocol and selecting cut-points calibrated in patients with cardiovascular diseases. Finally, it is necessary to develop a new tailored questionnaire that considers walking intensity and is adjusted to the current World Health Organisation recommendations, which use non-bouted metrics. (Sour...
Source: ESC Heart Failure - October 16, 2023 Category: Cardiology Authors: Carles Blasco ‐Peris,
Vicente Climent‐Paya,
Tomas Vetrovsky,
María I. García‐Álvarez,
Agustín Manresa‐Rocamora,
Vicente J. Beltrán‐Carrillo,
José Manuel Sarabia Tags: Original Article Source Type: research
Biochemical and biophysical properties of a rare TTRA81V mutation causing mild transthyretin amyloid cardiomyopathy
ConclusionsWe identified a patient with hATTR-CM who possesses a rare TTRA81V mutation solely associated with cardiac complications. The slightly reduced kinetic stability of this mutation indicates its late-onset nature and contributes to the gradual progression of the disease. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 13, 2023 Category: Cardiology Authors: Qiuyan Sha,
Yanli Zhang,
Mengdie Wang,
Jialu Sun,
Yunlong Zhang,
Xinxin Zhang,
Ning Wang,
Yu Liu,
Ying Liu Tags: Original Article Source Type: research
Correction to “Long‐term prognosis of patients treated by coronary sinus‐based percutaneous annuloplasty: single centre experience”
(Source: ESC Heart Failure)
Source: ESC Heart Failure - October 12, 2023 Category: Cardiology Tags: Correction Source Type: research
Serum apolipoprotein B to apolipoprotein A ‐I ratio predicts mortality in patients with heart failure
ConclusionsSerum ApoB/ApoA-I ratio is an independent predictor for the prognosis of HF patients. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 12, 2023 Category: Cardiology Authors: Shiyang Li,
Xiaoshuang Xie,
Xiaobin Zeng,
Shihai Wang,
Jianjun Lan Tags: Original Article Source Type: research
Issue Information
No abstract is available for this article. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 12, 2023 Category: Cardiology Tags: Issue Information Source Type: research
Preoperative sST2 levels relate to myocardial remodeling and cardiac function improvement after cardiac valve surgery
ConclusionsPreoperative sST2 levels are related to early postoperative myocardial remodelling and have a predictive value for the improvement of cardiac function 1 month after surgery. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 11, 2023 Category: Cardiology Authors: Yan Zhu,
Lipeng Pei,
Ning Li,
Yan Zhu Tags: Original Article Source Type: research
Uric acid is a biomarker for heart failure, but not therapeutic target: result from a comprehensive meta ‐analysis
ConclusionsUric acid is an independent predictor of heart failure occurrence and adverse prognosis. Targeting uric acid lowering as a therapeutic intervention does not improve the prognosis of patients with heart failure. It may not be advisable to use traditional urate-lowering drugs in young patients with heart failure, and elderly patients should exercise caution when using them. (Source: ESC Heart Failure)
Source: ESC Heart Failure - October 11, 2023 Category: Cardiology Authors: Shiwei Qin,
Meilin Xiang,
Lei Gao,
Xiaocheng Cheng,
Dongying Zhang Tags: Original Article Source Type: research
