Transjugular tricuspid valve ‐in‐ring replacement using the novel system under three‐dimensional printing guidance
We present a case of a 67-year-old male who underwent tricuspid annuloplasty 3 years ago and developed severe recurrent tricuspid regurgitation (regurgitation volume = 36 mL) 6 months ago. To avoid a high-risk thoracotomy, we finally performed TVIR replacement using the novel device, LuX-Valve Plus system, via the transjugular approach. Cardiovascular three-dimensional p rinting technology was utilized to investigate the distinct advantages offered by the new device in this specific intervention, as well as to simulate the procedure. Successful TVIR replacement resulted in significant symptomatic improvement. TVIR re...
Source: ESC Heart Failure - November 21, 2023 Category: Cardiology Authors: Yiwei Wang,
Yang Liu,
Jian Yang Tags: Case Report Source Type: research
Accelerometer vs. other activity measures in heart failure with preserved ejection fraction: the VITALITY ‐HFpEF trial
ConclusionsAccelerometer-based activity measures did not correlate with subjective or objective standard measures of health status and functional capacity in heart failure with preserved ejection fraction. Further investigation of their relationships to clinical outcomes is required. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 21, 2023 Category: Cardiology Authors: Javed Butler,
Muhammad Shahzeb Khan,
Tomasz Gasior,
Tyler R. Erickson,
Vanja Vlajnic,
Frank Kramer,
Robert O. Blaustein,
David Goldsbury,
Lothar Roessig,
Carolyn S.P. Lam,
Kevin J. Anstrom,
Paul W. Armstrong,
for the VITALITY Study Group Tags: Original Article Source Type: research
Association of anaemia on heart failure and left ventricular function: A bidirectional Mendelian randomization study
ConclusionsThis MR study supports the genetic evidence that there is bidirectional causality between anaemia and the risk of HF as well as anaemia may cause left ventricular hypertrophy and enlargement of the left atrium. Considering the adverse causal effects between the two diseases, more attention should be paid to the prevention and treatment of anaemia in patients with HF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 21, 2023 Category: Cardiology Authors: Yuchen Ying,
Jiachun Ye,
Zhechen Yuan,
Dihui Cai Tags: Original Article Source Type: research
Empagliflozin cost ‐effectiveness analysis in Japanese heart failure with mildly reduced and preserved ejection fraction
ConclusionsEmpagliflozin was demonstrated to be cost-effective for patients with HFpEF in Japan based on EMPEROR-Preserved trial data. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 16, 2023 Category: Cardiology Authors: Hiroyuki Tsutsui,
Hiroyuki Sakamaki,
Shin ‐ichi Momomura,
Yasushi Sakata,
Yutaro Kotobuki,
Stephan Linden,
Koki Idehara,
Daisuke Nitta Tags: Original Article Source Type: research
Calcium channel blockers and clinical outcomes in patients with continuous ‐flow left ventricular assist devices
ConclusionsIn patients with LVAD, CCB therapy fails to show benefits in long-term survival and is associated with increased incidences of neurological dysfunction, bleeding, renal dysfunction, and rehospitalization. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 16, 2023 Category: Cardiology Authors: Hongtao Tie,
Zhenhan Li,
Henryk Welp,
Avirup Guha,
C ésar Caraballo,
Heinz Deschka,
Rui Shi,
Xiaoqing Zheng,
Sven Martens,
Jürgen Sindermann,
Dan Chen,
Qingchen Wu,
Sabrina Martens Tags: Original Article Source Type: research
Identification of the communal pathogenesis and immune landscape between viral myocarditis and dilated cardiomyopathy
ConclusionsThree key genes (BLC6, FOXO1, and UBE2M) were identified and provided new insights into the diagnosis and treatment of VMC with DCM. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 16, 2023 Category: Cardiology Authors: Zhe Lei,
Jianlei Cao,
Jiahe Wu,
Yi Lu,
Lihua Ni,
Xiaorong Hu Tags: Original Article Source Type: research
Multimodal characterization of dilated cardiomyopathy: Geno ‐ And Phenotyping of PrImary Cardiomyopathy (GrAPHIC)
ConclusionsThe GrAPHIC will contribute to a better understanding of the heterogeneous nature of primary CMPs focusing on DCM and provide improved prognostic approaches and more individualized therapies. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 15, 2023 Category: Cardiology Authors: Laura Keil,
Filip Berisha,
Stella Ritter,
Johanna Skibowski,
Hariharan Subramanian,
Viacheslav O. Nikolaev,
Christian Kubisch,
Rixa Woitschach,
Larissa Fabritz,
Raphael Twerenbold,
Stefan Blankenberg,
S ören Weidemann,
Tanja Zeller,
Paulus K Tags: Study Design Source Type: research
Ivabradine could not decrease mitral regurgitation triggered atrial fibrosis and fibrillation compared with carvedilol
ConclusionsAlthough both ivabradine and carvedilol, at least in part, mitigated MR-induced chamber dilatation and decreased compliance, carvedilol had a better effect on reversing MR-induced cardiac fibrosis, apoptosis, and arrhythmogenesis than ivabradine. When compared with Ivabradine, MR rats treated with carvedilol exhibited a shorter duration and reduced inducibility of AF, thus providing more effective suppression of HCN4. Further investigations are required to validate our findings. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 14, 2023 Category: Cardiology Authors: Wei ‐Chieh Lee,
Yu‐Wen Lin,
Jhih‐Yuan Shih,
Zhih‐Cherng Chen,
Nan‐Chun Wu,
Wei‐Ting Chang Tags: Original Article Source Type: research
Fibroblast growth factor 23 independently predicts adverse outcomes after an acute coronary syndrome
ConclusionsFGF23 and other components of MM are independent predictors of HF and death after an ACS. This effect is homogeneous across different subgroups of population, and it is not limited to patients with chronic kidney disease. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 11, 2023 Category: Cardiology Authors: Andrea Kallmeyer,
Ana Pello,
Ester C ánovas,
Álvaro Aceña,
María Luisa González‐Casaus,
Nieves Tarín,
Carmen Cristóbal,
Carlos Gutiérrez‐Landaluce,
Ana Huelmos,
Aida Rodríguez‐Valer,
Óscar González‐Lorenzo,
Joaquín Alonso,
Tags: Original Article Source Type: research
Enhancing myocardial function with cardiac contractility modulation: potential and challenges
AbstractCardiac contractility modulation (CCM) offers a novel therapeutic avenue for heart failure patients, particularly those unresponsive to cardiac resynchronization therapy within specific QRS duration ranges. This review elucidates CCM's mechanistic underpinnings, its impact on myocardial function, and utility across patient demographics. However, CCM is limited by insufficient data on mortality and hospitalization rate reductions, as well as the need for specialized device implantation skills. While prevailing research has concentrated on left ventricular effects, a knowledge gap persists for other patient subsets. ...
Source: ESC Heart Failure - November 10, 2023 Category: Cardiology Authors: Zihan Li,
Qiming Liu,
Shenghua Zhou,
Yichao Xiao Tags: Review Source Type: research
Cost –utility of cardiac contractility modulation in patients with heart failure with reduced ejection fraction in Italy
ConclusionsFor patients with heart failure with reduced ejection fraction, CCM therapy could be cost-effective when taking a lifetime horizon. Further long-term, post-approval clinical studies are needed to verify these results in a real-world context, particularly concerning the effect of CCM therapy on mortality. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 9, 2023 Category: Cardiology Authors: Maria Lucia Narducci,
Mario Cesare Nurchis,
Federico Ballacci,
Federica Giordano,
Giovanna Elisa Calabr ò,
Massimo Massetti,
Filippo Crea,
Nadia Aspromonte,
Gianfranco Damiani Tags: Original Article Source Type: research
Self ‐efficacy and healthcare costs in patients with chronic heart failure or chronic obstructive pulmonary disease
ConclusionsThe findings show that an increased or sustained self-efficacy is associated with lower direct costs in patients with CHF or COPD. Person-centred phone contacts used as an add-on to usual care could result in lower direct costs for those with stable or increasing self-efficacy. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 9, 2023 Category: Cardiology Authors: Elin Blanck,
Laura Pirhonen N ørmark,
Andreas Fors,
Inger Ekman,
Lilas Ali,
Karl Swedberg,
Hanna Gyllensten Tags: Original Article Source Type: research
Phenotyping patients with ischaemic heart disease at risk of developing heart failure: an analysis of the HOMAGE trial
ConclusionsIn patients at risk of developing HF, those with CAD or MI had a different proteomic profile regarding inflammatory, immunological, and collagen catabolic processes. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 8, 2023 Category: Cardiology Authors: Diogo Santos ‐Ferreira,
Sílvia O. Diaz,
João Pedro Ferreira,
Nicolas Girerd,
Pierpaolo Pellicori,
Beatrice Mariottoni,
Franco Cosmi,
Mark Hazebroek,
Job A.J. Verdonschot,
Joe Cuthbert,
Johannes Petutschnigg,
Stephane Heymans,
Jan A. Staess Tags: Original Article Source Type: research
Regional differences and coronary microvascular dysfunction in heart failure with preserved ejection fraction
ConclusionsDespite regional differences in clinical characteristics, CMD was present in the majority of patients with HFpEF across different regions of the world with the lowest prevalence in the United States. This difference was explained by differences in patient characteristics. CMD could be a common therapeutic target across regions. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 3, 2023 Category: Cardiology Authors: Mikael Erhardsson,
Ulrika Ljung Fax én,
Ashwin Venkateshvaran,
Sara Svedlund,
Antti Saraste,
Maria Lagerström Fermer,
Li‐Ming Gan,
Sanjiv J. Shah,
Jasper Tromp,
Carolyn SP Lam,
Lars H. Lund,
Camilla Hage Tags: Short Communication Source Type: research
A novel ‘shunt fraction’ method to derive native cardiac output during liberation from central VA ECMO
This report describes a novel ‘shunt fraction’ method to calculate intrinsic cardiac output in central (right atrial-to-aorta) ECMO. The physiological basis of this ‘shunt fraction’ method is described, followed by the case presentation that details the clinical application of this method of quantifying intrinsic cardiac output to guide weaning and liberation from central VA ECMO. (Source: ESC Heart Failure)
Source: ESC Heart Failure - November 2, 2023 Category: Cardiology Authors: Hoong Sern Lim Tags: Case Report Source Type: research
