Long ‐term cost‐effectiveness of transcatheter mitral valve repair in  HF patients with secondary mitral regurgitation
ConclusionsMitraClip  + guideline-directed medical therapy was cost-effective in heart failure patients with secondary mitral regurgitation in the United Kingdom, Germany, and the United States, but not in mainland China from the perspective of the national healthcare system. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 22, 2024 Category: Cardiology Authors: Younan Yao, Ziyou Zhou, Tian Geng, Anping Cai, Tian Li, Junqing Yang, Jiyan Chen, Liwen Li Tags: Original Article Source Type: research

Impact of heart rate changes during hospitalization on outcome in heart failure with preserved ejection fraction
ConclusionsIn hospitalized HFpEF patients, excessive HR dropping during hospitalization is associated with an increased risk of CV death or HF rehospitalization. These findings highlight the importance of HR monitoring and avoiding excessively slowing down HR in hospitalized HFpEF patients to reduce the risk of CV events. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 22, 2024 Category: Cardiology Authors: Dan Liu, Xiaotong Cui, Yamei Xu, Lei Xu, Zhonglei Xie, Shuai Yuan, Peng Wang, Yanyan Wang, Sanli Qian, Hui Gong, Peter Nordbeck, Jiefu Yang, Jingmin Zhou, Junbo Ge, Aijun Sun Tags: Original Article Source Type: research

Analysis of the serum levels of RIP3 and Drp1 in patients with heart failure
ConclusionsIn this pilot study, findings on serum RIP3 supported the importance of necroptosis in HF pathomechanisms. The potential diagnostic use of circulating RIP3, unlike Drp1, as an additional biomarker of HF has also been indicated; however, further large studies are needed to prove this concept. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 21, 2024 Category: Cardiology Authors: Izabela Jarabicov á, Csaba Horváth, Martin Chudý, Eva Goncalvesová, Adriana Adameová Tags: Short Communication Source Type: research

Cardiovascular disease healthcare trajectories: descriptions, similarities, mortality rates of heart failure in France
ConclusionsWe highlight the value of healthcare trajectories on frequent hospitalization sequences, mortality, and prognosis and indicate the necessary prognostic value of HF re-hospitalization. Our work may be an essential tool for better identification of at-risk patients in order to increase and improve personalized care in the future. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 21, 2024 Category: Cardiology Authors: Camille Nevoret, Yohann Tran, Soulef Guendouz, Audrey Lavenu, Sandrine Katsahian, Thibaud Damy, Anne ‐Isabelle Tropeano Tags: Original Article Source Type: research

Assessing the diversity and determinants of health ‐related quality of life measures in patients with acute heart failure
ConclusionsThis study illuminates the variance in HR-QoL measurement tools for Taiwanese HFrEF patients. Using a range of these tools is beneficial in unveiling diverse determinants and approaching comprehensive patient-centred care. However, for a more precise HR-QoL assessment in Taiwanese HFrEF patients, recalibrating the EQ-5D-derived utility scores might be necessary, emphasizing the importance of patient-specific considerations within the HF-PAC programme. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 21, 2024 Category: Cardiology Authors: Dhrumil Patil, Hsin ‐Ju Tang, Fang‐Hsiu Kuo, Han Siong Toh, I‐Ning Yang, Wei‐Ting Chang, Mei‐Chuan Lee, Kai‐Ning Chung, Chi‐Ya Huang, Wan‐Hsuan Hsu, Ting‐Chia Chang, Jhih‐Yuan Shih, Chia‐Te Liao Tags: Original Article Source Type: research

Novel SCN5A gene mutation in a patient affected by multifocal ectopic premature Purkinje ‐related contractions syndrome
We report the case of a 36-year-old woman who presented to the emergency department complaining of palpitations and asthenia. Investigations showed frequent ventricular ectopy and severe left ventricular ejection fraction impairment. She was diagnosed with a peculiar condition defined multifocal ectopic premature Purkinje-related contractions syndrome, which in some cases can be associated with a dilated cardiomyopathy phenotype. Genetic testing showed a novel mutation in the SCN5A gene (c.673C  >  G). In the context of acute left ventricular dysfunction in a young patient, we discuss the clinical presentation of this...
Source: ESC Heart Failure - March 20, 2024 Category: Cardiology Authors: Nicoletta Ventrella, Lorenzo Bianchini, Stefania Riva, Francesca Pizzamiglio, Maria Antonietta Dessanai, Fabrizio Tundo, Tommaso Sattin, Francesca De Lio, Selene Cellucci, Claudio Tondo Tags: Case Report Source Type: research

Assessing the impact of haemodynamic monitoring with CardioMEMS on heart failure patients: a cost –benefit analysis
ConclusionsBased on the results, we suggest that remote monitoring of pulmonary artery pressure with the CardioMEMS HF System represents a midterm and long-term efficient strategy in a healthcare setting in Southern Europe. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 19, 2024 Category: Cardiology Authors: Pau Codina, Jos é Ángel Vicente Gómez, Guillem Hernández Guillamet, Laura Ricou Ríos, Andrea Carrete, Victoria Vilalta, Oriol Estrada, Jordi Ara, Josep Lupón, Antoni Bayés‐Genís, Francesc López Seguí Tags: Original Article Source Type: research

Pupil reflex as a marker of activity and prognosis in heart failure: a longitudinal and prospective study
ConclusionsPupillometry may be a new, non-invasive, and simple tool to determine the status of SNS, help in the prognostic stratification of acute HF patients, and improve therapeutic management. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 18, 2024 Category: Cardiology Authors: Margarita Zamorano, Juan Manuel Monteagudo, Eduardo Gonz ález, Isabel Rayo, Sara Fernández, Miguel Castillo, Qiheng Zhou, Pedro de la Villa, Jose Luis Zamorano Tags: Original Article Source Type: research

Obesity: the perfect storm for heart failure
AbstractObesity condition causes morphological and functional alterations involving the cardiovascular system. These can represent the substrates for different cardiovascular diseases, such as atrial fibrillation, coronary artery disease, sudden cardiac death, and heart failure (HF) with both preserved ejection fraction (EF) and reduced EF. Different pathogenetic mechanisms may help to explain the association between obesity and HF including left ventricular remodelling and epicardial fat accumulation, endothelial dysfunction, and coronary microvascular dysfunction. Multi-imaging modalities are required for appropriate rec...
Source: ESC Heart Failure - March 16, 2024 Category: Cardiology Authors: Maria Lembo, Teresa Strisciuglio, Celeste Fonderico, Costantino Mancusi, Raffaele Izzo, Valentina Trimarco, Alessandro Bellis, Emanuele Barbato, Giovanni Esposito, Carmine Morisco, Speranza Rubattu Tags: Review Source Type: research

Correction to “Impedance‐based remote monitoring in patients with heart failure and concomitant chronic kidney disease”
(Source: ESC Heart Failure)
Source: ESC Heart Failure - March 15, 2024 Category: Cardiology Tags: Correction Source Type: research

Optimal combination of right ventricular functional parameters using echocardiography in pulmonary arterial hypertension
ConclusionsThe combination models for RV function outperformed any single parameter in identifying the risk profile of patients with PAH. Comprehensive assessment of RV –pulmonary artery coupling using multiparametric methods is clinically meaningful in patients with PAH. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 15, 2024 Category: Cardiology Authors: Qimou Li, Yu Zhang, Xiaopei Cui, Weida Lu, Qiushang Ji, Mei Zhang Tags: Original Article Source Type: research

Socio ‐economic position, multimorbidity, and health care utilization among Danish left ventricular assist device patients
ConclusionsAmong patients who underwent LVAD implantation, health care utilization was high in the early post-LVAD discharge phase and was influenced by socio-economic position. Multimorbidity influenced the number of in-hospital days and redeemed prescriptions during the 2  year follow-up. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 15, 2024 Category: Cardiology Authors: Inge Schj ødt, Rikke E. Mols, István Bakos, Erzsébet Horváth‐Puhó, Finn Gustafsson, Søren L. Kristensen, Johan E. Larsson, Bo Christensen, Hans Eiskjær, Brian B. Løgstrup Tags: Original Article Source Type: research

Impact of epicardial adipose tissue on cardiac function and morphology in patients with diastolic dysfunction
ConclusionsPatients with diastolic dysfunction and increased EAT show more pronounced signs of diastolic functional failure and adverse structural remodelling. Despite similar morphological characteristics, patients with high EAT show significant cardiac functional impairment, in particular in the atria. Our results indicate that regionally increased EAT directly induces atrial functional failure, which represents a distinct pathophysiological feature in HFpEF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 14, 2024 Category: Cardiology Authors: Alexander Schulz, S ören J. Backhaus, Torben Lange, Ruben Evertz, Shelby Kutty, Johannes T. Kowallick, Gerd Hasenfuß, Andreas Schuster Tags: Original Article Source Type: research

Systemic sclerosis is associated with increased in ‐patient mortality in patients hospitalized for heart failure
ConclusionsIn patients hospitalized for HF, those with SSc were noted to have higher odds of in-hospital mortality than those without SSc. Patients with HF and SSc were more likely to be younger, female, and have higher rates of co-morbid interstitial lung disease and pulmonary hypertension at baseline with fewer traditional cardiovascular risk factors. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 13, 2024 Category: Cardiology Authors: Akil A. Sherif, Vinit J. Gilvaz, Sonu Abraham, Anu Mariam Saji, Don Mathew, Ameesh Isath, Aiswarya Rajendran, Johanna Contreras, Gregg M. Lanier, Anthony M. Reginato Tags: Original Article Source Type: research

Renal ultrasonography predicts worsening renal function in patients with heart failure under tolvaptan administration
ConclusionsTolvaptan increased the PSV and EDV of the interlobar artery, which may mean tolvaptan increased renal blood flow. The renal artery AT may be a surrogate for worsening renal function. (Source: ESC Heart Failure)
Source: ESC Heart Failure - March 12, 2024 Category: Cardiology Authors: Nobukiyo Tanaka, Yoshio Furukawa, Takuya Maeda, Hiroki Ishihara, Kazuhiro Dan, Masanori Teramura, Kei Ichihashi, Tetsuro Takase, Yuya Takahashi, Daichi Tsuzura, Akira Shinoda, Masato Fujii, Hisashi Okada, Fumiharu Itabashi, Tomohiko Teramoto Tags: Original Article Source Type: research