Prognostic models for patients suffering a heart failure with a preserved ejection fraction: a systematic review
AbstractThe purpose of this study was to systematically review the development, performance, and applicability of prognostic models developed for predicting poor events in patients with heart failure with preserved ejection fraction (HFpEF). Databases including Embase, PubMed, Web of Science Core Collection, the Cochrane Library, China National Knowledge Infrastructure, Wan Fang, Wei Pu, and China Biological Medicine were queried from their respective dates of inception to 1 June 2023, to examine multivariate models for prognostic prediction in HFpEF. Both forward and backward citations of all studies were included in our ...
Source: ESC Heart Failure - February 6, 2024 Category: Cardiology Authors: Ying ‐Ying Jia,
Nian‐Qi Cui,
Ting‐Ting Jia,
Jian‐Ping Song Tags: Review Source Type: research
Narrative synthesis of the effectiveness and characteristics of heart failure disease self ‐management support programmes
AbstractA deeper understanding of the key elements that should be included in heart failure (HF) disease self-management support (DSMS) programmes is crucial to enhance programme effectiveness and applicability to diverse settings. We investigated the characteristics and effectiveness of DSMS programmes designed to improve survival and decrease acute care readmissions for people with HF and determine the generalizability and applicability of the evidence to low- and middle-income countries (LMICs). A narrative meta-synthesis approach was used, and systematic reviews of randomized controlled trials (RCTs) of DSMS programmes...
Source: ESC Heart Failure - February 5, 2024 Category: Cardiology Authors: Apinya Koontalay,
Mari Botti,
Anastasia Hutchinson Tags: Review Source Type: research
Heart failure outcomes by left ventricular ejection fraction in a contemporary region ‐wide patient cohort
ConclusionsThis study of contemporary patients with incident HF demonstrates that those with HFpEF and HFrEF differ considerably in terms of clinical presentation, prognosis, and care, highlighting a potential to improve HF outcomes. (Source: ESC Heart Failure)
Source: ESC Heart Failure - February 5, 2024 Category: Cardiology Authors: Johan Sundstr öm,
Johan Ärnlöv,
Stelios Karayiannides,
Johan Bodegard,
Karolina Ersmark,
Stefan Gustafsson,
Thomas Cars,
Maria K. Svensson,
Anna Norhammar Tags: Original Article Source Type: research
A prediction model for estimating NT ‐proBNP in a general Japanese population: the Toon Health Study
ConclusionsThis study introduces the first prediction model for NT-proBNP in a general Japanese population. Although the model has acceptable performance, ongoing refinement is essential. Our transparent approach to model development, alongside a web-based interactive tool, lays the groundwork for further improvements and external validation. The OPR holds potential for predicting the future risk of HFpEF. This research contributes to understanding the nuanced influence of patient backgrounds on levels of NT-proBNP in asymptomatic individuals within the context of a broader population-based cohort study. (Source: ESC Heart Failure)
Source: ESC Heart Failure - February 2, 2024 Category: Cardiology Authors: Katsuji Inoue,
Kazumichi Yamamoto,
Haruhiko Higashi,
Yasunori Takata,
Shinji Inaba,
Shigehiro Miyazaki,
Akinori Higaki,
Makoto Saito,
Haruhiko Osawa,
Osamu Yamaguchi Tags: Original Article Source Type: research
Transcatheter edge ‐to‐edge repair in papillary muscle injury complicating acute myocardial infarction
ConclusionsTEER is a feasible therapy in critically ill patients with PMR due to a recent MI. TEER may have a role as salvage treatment or bridge to surgery in this population. (Source: ESC Heart Failure)
Source: ESC Heart Failure - February 2, 2024 Category: Cardiology Authors: Dan Haberman,
Rodrigo Est évez‐Loureiro,
Andrew Czarnecki,
Paolo Denti,
Pedro Villablanca,
Konstantinos Spargias,
Doron Sudarsky,
Leor Perl,
Paul Fefer,
Lisa Manevich,
Giulia Masiero,
Luis Nombela‐Franco,
Lion Poles,
Berenice Caneiro‐Q Tags: Original Article Source Type: research
CircRbms1 fosters MST1 mRNA and protein levels to motivate myocardial ischaemia –reperfusion injury via autophagic status
ConclusionsCircRbms1 inhibited the miR-142-3p/MST1 axis and played a protective role in myocardial I/R injury. It may provide a new therapeutic target for I/R heart injury. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 30, 2024 Category: Cardiology Authors: Qin Liu,
Guorong Lai,
Yanhui Hu,
Fan Yang,
Chao Zhang,
Dongsheng Le,
Fumou Deng,
Xianliang Xing,
Binquan Tang,
Huanhuan Jie,
Yingping Liang,
Enjun Lei Tags: Original Article Source Type: research
Taking a walk on the heart failure side: comparison of metabolic variables during walking and maximal exertion
ConclusionsThe 6MWT can be a maximal effort especially in most severe HF patients and suggest that, in absence of prognostic studies related to 6MWT metabolic values, CPET should remain the first method of choice in the functional assessment of patients with HF as well as in sport medicine. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 30, 2024 Category: Cardiology Authors: Massimo Mapelli,
Elisabetta Salvioni,
Alice Bonomi,
Mara Paneroni,
Rosa Raimondo,
Paola Gugliandolo,
Irene Mattavelli,
Jacopo Bidoglio,
Kiran K. Mirza,
Maria Teresa La Rovere,
Finn Gustafsson,
Piergiuseppe Agostoni Tags: Short Communication Source Type: research
Too young for an acquired cardiomyopathy? Cobalt metallosis as a cardiac amyloidosis mimicker
We report the case of a young female referred to our centre for the suspicion of cardiac amyloidosis presenting with low electrocardiogram voltage, left ventricular hypertrophy, pericardial effusion, and global and longitudinal systolic impairment with apical sparing pattern. Her medical history was remarkable for arthroplasty in the context of congenital hip dysplasia. Two years prior to presentation, she underwent revision surgery for prosthesis malfunction, and tissue metallosis was initially documented. At the current presentation, cobalt metallosis was confirmed, as the circulating cobalt and chromium levels were seve...
Source: ESC Heart Failure - January 30, 2024 Category: Cardiology Authors: Mihnea Casian,
Ramona Bica,
Virgil Ionescu,
Vlad Predescu,
Radu Țincu,
Ruxandra Jurcuț Tags: Case Report Source Type: research
Prognostic effect of systematic geriatric assessment on patients with acute heart failure
ConclusionsIn AHF patients, frailty and dependence implied a worse prognosis, rising mortality, readmissions, and ER visits for AHF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 30, 2024 Category: Cardiology Authors: Lara Aguilar ‐Iglesias,
Ana Merino‐Merino,
Ester Sanchez‐Corral,
Maria‐Jesus Garcia‐Sanchez,
Isabel Santos‐Sanchez,
Jesus Dominguez‐Calvo,
Ruth Saez‐Maleta,
Jose‐Angel Perez‐Rivera Tags: Original Article Source Type: research
Protective effect of secretory APE1/Ref ‐1 on doxorubicin‐induced cardiotoxicity via suppression of ROS and p53 pathway
ConclusionsOur study provides evidence that secretory APE1/Ref-1 has the potential to inhibit DOX-induced cardiac toxicity by inhibiting oxidative stress and p53 related apoptosis bothin vitro andin vivo. These findings suggest that secretory APE1/Ref-1 supplementation is a promising strategy to attenuate DOX-induced cardiomyocyte damage in a preclinical model. Further clinical investigations are essential to validate the therapeutic efficacy and safety of the intervention in human subjects. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 30, 2024 Category: Cardiology Authors: Soo Yeon An,
Seon ‐Ah Jin,
Hee Jeong Seo,
Yu Ran Lee,
Sungmin Kim,
Byeong Hwa Jeon,
Jin‐Ok Jeong Tags: Original Article Source Type: research
Anxiety disorder and cardiovascular disease: a two ‐sample Mendelian randomization study
ConclusionsAnxiety disorders were causally associated with greater risk of CHD, MI, and HF but not AF among individuals of European descent. Further research on mediating mechanisms and in diverse populations is warranted. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 28, 2024 Category: Cardiology Authors: Bo Peng,
Hong Meng,
Liang Guo,
Jun Zhu,
Bin Kong,
Zongze Qu,
Wei Shuai,
He Huang Tags: Original Article Source Type: research
Estimating the clinical and budgetary impact of using angiotensin receptor neprilysin inhibitor as first line therapy in patients with HFrEF
ConclusionsIncreasing the proportion of patients receiving ARNI instead of angiotensin converting enzyme inhibitors as first-line treatment of HFrEF will lead to a considerable number of additional life years gained and prevented hospitalizations but with additional cost in terms of health care expenditure in Sweden and in the United Kingdom. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 27, 2024 Category: Cardiology Authors: Nicklas Bergh,
Krister Lindmark,
Johannes Lissdaniels,
Gustav Lanne,
Oskar K äck,
Martin R. Cowie Tags: Original Article Source Type: research
Computed tomography or chest X ‐ray to assess pulmonary congestion in dyspnoeic patients with acute heart failure
ConclusionsIn consecutive dyspnoeic patients admitted to the emergency department, LDCT is significantly better than chest radiographs in detecting pulmonary congestion. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 27, 2024 Category: Cardiology Authors: Kristina Miger,
Anne Sophie Overgaard Olesen,
Johannes Grand,
Andreas Fabricius ‐Bjerre,
Ahmad Sajadieh,
Nis Høst,
Nanna Køber,
Annemette Abild,
Lars Pedersen,
Hans Henrik Lawaetz Schultz,
Christian Torp‐Pedersen,
Mikael Ploug Boesen,
Je Tags: Original Article Source Type: research
Multifactorial risk factors for hospital readmissions among patients with symptoms of advanced heart failure
ConclusionsRisk factors for hospital readmissions and mortality are multifactorial. Many of these factors, such as weak grip strength, diabetes, poor self-care behaviours, are potentially modifiable and should be routinely assessed and managed in cardiac clinics and hospital admissions. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 26, 2024 Category: Cardiology Authors: Chetna Malhotra,
Isha Chaudhry,
Yeo Khung Keong,
Kheng Leng David Sim Tags: Original Article Source Type: research
Twelve ‐month follow‐up results from the SIRONA 2 clinical trial
ConclusionsLong-term follow-up of the SIRONA 2 trial supports the safety and accuracy of the Cordella PA Sensor System in enabling comprehensive HF management in NYHA class III HF patients. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 25, 2024 Category: Cardiology Authors: Faisal Sharif,
Stephen Rosenkranz,
Jozef Bartunek,
Tibor Kempf,
Birgit A ßmus,
Niall G. Mahon,
Nicholas J. Hiivala,
Wilfried Mullens Tags: Original Article Source Type: research
