Musculoskeletal co ‐morbidities in patients with transthyretin amyloid cardiomyopathy: a systematic review
AbstractThe prevalence of transthyretin-associated amyloidosis cardiomyopathy (ATTR-CM) has grown because of newer non-invasive diagnosis tools. Detecting the presence of extra-cardiac ATTR manifestations such as musculoskeletal pathologies considered ‘red flags’, when there is minimal or non-cardiac clinical involvement is primordial to carry out an early diagnosis. The aim of this systematic review is to examine the prevalence of musculoskeletal, ATTR-deposition-related co-morbidities in patients already diagnosed with ATTR-CM, specifically carpal tunnel syndrome, ruptured biceps tendon, spinal stenosis, and trigger ...
Source: ESC Heart Failure - December 22, 2023 Category: Cardiology Authors: Francesc Formiga,
Laia Saumell Baeza,
David Chivite,
Sergi Yun Tags: Review Source Type: research
Angiographic classification of total occlusion and its implication on balloon pulmonary angioplasty
ConclusionsOcclusion morphology has a significant impact on BPA success and complication rates. A treatment strategy tailored to each specific occlusive lesion, as outlined in the present study, has the potential to serve as a valuable guide for clinical practitioners. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 21, 2023 Category: Cardiology Authors: Tao Yang,
Xin Li,
Qin Luo,
Qing Zhao,
Qixian Zeng,
Yi Zhang,
Anqi Duan,
Zhihua Huang,
Meixi Hu,
Sicheng Zhang,
Luyang Gao,
Changming Xiong,
Zhihui Zhao,
Zhihong Liu Tags: Original Article Source Type: research
Incidence and predictors of heart failure with improved ejection fraction category in a HFrEF patient population
ConclusionsIn our study, in this HFrEF patient population managed in a heart failure outpatient clinic, the 1 year incidence of HFimpEF was found to be ~20%. The 1 year incidence of HFimpEF decreased in relation to time since diagnosis of HFrEF. The most important predictors of the development of HFimpEF were female sex, non-ischaemic aetiology, narrower QRS width, and smaller diameter of the left ventri cle and left atrium. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 21, 2023 Category: Cardiology Authors: Bal ázs Solymossi,
Balázs Muk,
Róbert Sepp,
Tamás Habon,
Attila Borbély,
Krisztina Heltai,
Zsuzsanna Majoros,
Zoltán Járai,
Dénes Vágány,
Ákos Szatmári,
Erzsébet Sziliczei,
Fanni Bánfi‐Bacsárdi,
Noémi Nyolczas Tags: Original Article Source Type: research
Safety of sodium ‐glucose cotransporter 2 inhibitors drugs among heart failure patients: a systematic review and meta‐analysis
AbstractSodium –glucose cotransporter-2 inhibitors (SGLT2is) reduce morbidity and mortality for heart failure (HF) patients and are recommended as cornerstones for their medical therapy. Utilization in clinical practice remains low for multiple reasons, one of which may be adverse events. We investigated the inc idence of these events to see if they are associated with SGLT2i use. A systematic search was performed in databases, including PubMed, Embase, Cochrane Library,Clinicaltrials.gov, and WHO's International Clinical Trials Registry Platform. Relevant randomized controlled trial studies assessing the safety outcomes...
Source: ESC Heart Failure - December 21, 2023 Category: Cardiology Authors: Hamidreza Soleimani,
Behrad Saeedian,
Yeganeh Pasebani,
Nastaran Babajani,
Amirreza Pashapour Yeganeh,
Pegah Bahirai,
Hossein Navid,
Ahmad Amin,
Marc D. Samsky,
Micheal G. Nanna,
Kaveh Hosseini Tags: Review Source Type: research
Insulin resistance in Takotsubo syndrome
ConclusionsElevated initial plasma glucose was associated with adverse outcome-relevant parameters in TTS and may present a surrogate parameter of heightened catecholaminergic drive. In mice, insulin- and glucose injection both improved EPI-induced AHF and myocardial damage, indicating insulin resistance rather than detrimental effects of hyperglycaemia itself as the underlying cause. Future studies will investigate the role of HbA1c as a risk stratifier and of insulin-based therapy in TTS. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 21, 2023 Category: Cardiology Authors: Bastian Bruns,
Maximilian Joos,
Nesrin Elsous,
Hugo A. Katus,
Jobst ‐Hendrik Schultz,
Norbert Frey,
Johannes Backs,
Benjamin Meder Tags: Original Article Source Type: research
Improvement in left atrial strain following ferric carboxymaltose in heart failure: an analysis of the Myocardial ‐IRON trial
ConclusionsIn patients with stable HF, LVEF < 50%, and ID, treatment with FCM was associated with short-term improvements in LA-LS assessed by CMR-FT. Future works should assess the potential benefit of iron repletion on LA function. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 20, 2023 Category: Cardiology Authors: Enrique Santas,
Irene del Canto,
Ingrid Cardells,
Gema Mi ñana,
Pau Llàcer,
Luis Almenar,
Lorenzo Fácila,
Alicia M. Maceira,
Juan Sanchis,
Julio Núñez, on behalf of
Myocardial‐IRON Investigators Tags: Short Communication Source Type: research
Geriatric Nutritional Risk Index predicts bleeding event in patients with heart failure
ConclusionsHeart failure patients with poor nutritional status, determined by GNRI under 106.2, experienced high bleeding event rates. Comprehensive management is required to avoid bleeding event in those populations. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 20, 2023 Category: Cardiology Authors: Yu Sato,
Akiomi Yoshihisa,
Yuji Nozaki,
Himika Ohara,
Yukiko Sugawara,
Satoshi Abe,
Tomofumi Misaka,
Takamasa Sato,
Masayoshi Oikawa,
Atsushi Kobayashi,
Takayoshi Yamaki,
Kazuhiko Nakazato,
Yasuchika Takeishi Tags: Original Article Source Type: research
N ‐terminal pro‐B‐type natriuretic peptide concentrations, testing and associations with worsening heart failure events
ConclusionsNT-proBNP testing increased over time but still was only performed in half of the patients. Testing was associated with a WHFE, with features of more severe HF and for differential diagnosis purposes. Increased and stable high levels were associated with a WHFE. Overall, our data highlight the potential benefits of carrying further implementation of NT-proBNP testing in clinical practice. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 20, 2023 Category: Cardiology Authors: Giulia Ferrannini,
Lina Benson,
Dominik Lautsch,
Ulf Dahlstr öm,
Lars H. Lund,
Gianluigi Savarese,
Juan Jesus Carrero Tags: Original Article Source Type: research
Use of intraoperative haemoadsorption in patients undergoing heart transplantation: a proof ‐of‐concept randomized trial
ConclusionsIntraoperative haemoadsorption was associated with better haemodynamic stability, mitigated PCT response, lower rates of post-operative AKI and RRT, more stable hepatic bilirubin excretion, and shorter durations of MV and ICU stay. Intraoperative haemoadsorption did not show any relevant adsorption effect on MPA. There was no increase in the frequency of early cardiac allograft rejection related to intraoperative haemoadsorption use. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 19, 2023 Category: Cardiology Authors: Endre Nemeth,
Adam Soltesz,
Eniko Kovacs,
Zsofia Szakal ‐Toth,
Eszter Tamaska,
Hajna Katona,
Kristof Racz,
Gergely Csikos,
Viktor Berzsenyi,
Szabolcs Fabry,
Zsuzsanna Ulakcsai,
Csilla Tamas,
Beata Nagy,
Marina Varga,
Bela Merkely Tags: Original Article Source Type: research
Autonomic nervous modulation: early treatment for pulmonary artery hypertension
AbstractPulmonary artery hypertension (PAH) is a chronic vascular disease defined by the elevation of pulmonary vascular resistance and mean pulmonary artery pressure, which arises due to pulmonary vascular remodelling. Prior research has already established a link between the autonomic nervous system (ANS) and PAH. Therefore, the rebalancing of the ANS offers a promising approach for the treatment of PAH. The process of rebalancing involves two key aspects: inhibiting an overactive sympathetic nervous system and fortifying the impaired parasympathetic nervous system through pharmacological or interventional procedures. Ho...
Source: ESC Heart Failure - December 18, 2023 Category: Cardiology Authors: Liu Xueyuan,
Xu Yanping,
Guan Jiaoqiong,
Yin Yuehui Tags: Review Source Type: research
Antiretroviral therapy and HIV ‐associated cardiovascular disease: a prospective cardiac biomarker and CMR tissue characterization study
ConclusionsOur cardiac biomarker data support the presence of subclinical myocardial injury, remodelling, and fibrosis at HIV diagnosis, and ART had a positive influence on these blood markers. It remains unclear if the underlying pathological processes were fully addressed by ART. The ability of cardiac biomarkers to detect and track tissue abnormalities diagnosed with CMR showed promise. With additional research, this could lead to improvements in screening and monitoring myocardial abnormalities, even in CMR-limited settings. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 16, 2023 Category: Cardiology Authors: Pieter ‐Paul S. Robbertse,
Anton F. Doubell,
Tonya M. Esterhuizen,
Philip G. Herbst Tags: Original Article Source Type: research
Treatment patterns and trajectories in patients after acute heart failure hospitalization
ConclusionsA substantial number of patients with HF experienced transitions to other categories after discharge. Notably, patients with decreased EF experienced a worse prognosis, even with slight decreases (e.g. HFpEF transitioning to HFmrEF). These findings emphasize the significance of longitudinal assessments of systolic function to better manage patients following acute decompensation. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 15, 2023 Category: Cardiology Authors: Ryo Nakamaru,
Yasuyuki Shiraishi,
Takashi Kohno,
Yuji Nagatomo,
Hiroki Akiyama,
Yuki Motoya,
Masato Fukui,
Toshitaka Yajima,
Tsutomu Yoshikawa,
Shun Kohsaka Tags: Original Article Source Type: research
Trajectory change of left ventricular ejection fraction after rhythm control for atrial fibrillation in heart failure
ConclusionsRhythm control is associated with improved LVEF trajectory and clinical outcomes and may thus be considered the optimal therapeutic strategy for patients with both HF and AF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 15, 2023 Category: Cardiology Authors: Jinping Si,
Yuxi Sun,
Lin Bai,
Gary Tse,
Zijie Ding,
Xinxin Zhang,
Yanli Zhang,
Xuefu Chen,
Yunlong Xia,
Ying Liu Tags: Original Article Source Type: research
Correlates of malnutrition in patients with heart failure: the role of social support
ConclusionsBesides the clinical conditions affecting the risk of malnutrition in patients with HF, social support may play an important role. Including this factor in HF guidelines and developing educational programmes may help improve HF patients' health. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 14, 2023 Category: Cardiology Authors: Mohammad Hossein Sharifi,
Maryam Afshari,
Hossein Molavi Vardanjani,
Amirreza Nikmanesh,
Mohammad Hossein Nikoo Tags: Original Article Source Type: research
Causal relationship between aspirin consumption and heart failure: a Mendelian randomization study
ConclusionsOur results support a potential positive causal relationship between aspirin consumption and the occurrence of heart failure. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 14, 2023 Category: Cardiology Authors: Wenyi Cai,
Zhang Fang,
Zhiqiang Tian,
Dianfu Li,
Kangting Tang Tags: Original Article Source Type: research
