Long ‐term outcomes and reverse remodelling in recently diagnosed unexplained left ventricular systolic dysfunction
ConclusionsLVRR occurs in over half of patients with recent onset unexplained LV systolic dysfunction during first 2  years of optimally guided heart failure therapy and then remains relatively stable during 5-year follow-up. Normalization of adverse LV remodelling corresponds to a low rate of mortality and heart failure hospitalizations during long-term follow-up. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 10, 2024 Category: Cardiology Authors: Petr Kuchynka, Jana Podzimkova, Josef Marek, Barbara Anna Danek, Ivana Vitkova, Miluse Kreidlova, Lenka Roblova, Tomas Kovarnik, Stanislav Simek, Jan Horak, Jan Habasko, Ales Linhart, Tomas Palecek Tags: Original Article Source Type: research

Effectiveness and safety of ivabradine in Chinese patients with chronic heart failure: an observational study
ConclusionsIvabradine treatment reduced HR and improved cardiac function and health-related quality of life in Chinese patients with chronic HF. Benefits were seen irrespective of whether or not patients were also taking ARNIs or beta-blockers. Treatment was well tolerated with a similar profile to previous ivabradine studies. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 9, 2024 Category: Cardiology Authors: Jingmin Zhou, Yamei Xu, Zhaofen Zheng, Shuyang Zhang, Jiefu Yang, Yuhui Zhang, Baopeng Tang, Huiyuan Han, Qing Zhang, Fan Liu, Wenhui Ding, Caizhen Qian, Guohai Su, Xiaohui Liu, Yuansheng Shen, Bei Shi, Xiangqing Kong, Zhiming Ge, Ping Z Tags: Original Article Source Type: research

The correlation between albumin ‐corrected anion gap and prognosis inpatients with acute myocardial infarction
ConclusionsElevated serum ACAG ( ≥20 mmol/L) is an independent risk factor for short-term and long-term mortality in critically ill patients with AMI, and it may assist clinicians and nurses identifying high-risk patients. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 2, 2024 Category: Cardiology Authors: Haiying Sheng, Jianhong Lu, Lei Zhong, Beiping Hu, Xu Sun, Huifeng Dong Tags: Original Article Source Type: research

The correlation between albumin ‐corrected anion gap and prognosis in patients with acute myocardial infarction
ConclusionsElevated serum ACAG ( ≥20 mmol/L) is an independent risk factor for short-term and long-term mortality in critically ill patients with AMI, and it may assist clinicians and nurses identifying high-risk patients. (Source: ESC Heart Failure)
Source: ESC Heart Failure - January 2, 2024 Category: Cardiology Authors: Haiying Sheng, Jianhong Lu, Lei Zhong, Beiping Hu, Xu Sun, Huifeng Dong Tags: Original Article Source Type: research

ESCHF ‐23‐00103R1 ‘Microvascular function and inflammatory activation in Takotsubo cardiomyopathy’
(Source: ESC Heart Failure)
Source: ESC Heart Failure - January 2, 2024 Category: Cardiology Authors: Ole Geir Solberg Tags: Letter to the Editor ‐ Reply Source Type: research

Changes over time in patient ‐reported outcomes in patients with heart failure
ConclusionIn total, 79% of the patients with HF encountered problems related to sleep, depressive symptoms, HrQoL, and well-being at least once during a 1-year period. This underscores the need for continuous monitoring and follow-up of patients with HF and the need for dynamic adjustments in treatment and care regularly throughout the HF trajectory. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 30, 2023 Category: Cardiology Authors: Tiny Jaarsma, Naoko P. Kato, Leonie Klompstra, Tuvia Ben Gal, Josiane Boyne, Eva H ägglund, Ercole Vellone, Andreas Hagenow, Lorraine S. Evangelista, Jan Mårtensson, Anna Strömberg Tags: Original Article Source Type: research

Invasive haemodynamics at rest and exercise in cardiac amyloidosis
ConclusionsMost patients with ATTR-CM have isolated post-capillary or combined pre- and post-capillary PH at rest, and almost all patients develop exercise-induced PH with a large post-capillary component. There was a pronounced, but balanced increase in atrial pressures on exercise. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 30, 2023 Category: Cardiology Authors: Margrethe Flesvig Holt, August Fl ø, Håvard Ravnestad, Vilde Bjørnø, Lars Gullestad, Arne K. Andreassen, Kaspar Broch, Einar Gude Tags: Short Communication Source Type: research

Effect of constipation on readmission for heart failure in patients with acute heart failure
ConclusionsConstipation status was strongly associated with a higher risk of readmission for heart failure in patients with acute heart failure. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 30, 2023 Category: Cardiology Authors: Shigeto Namiuchi, Atsushi Tanita, Shinichiro Sunamura, Kenta Onodera, Tsuyoshi Ogata, Kazuki Noda, Toru Takii, Yoshio Nitta, Seijiro Yoshida Tags: Original Article Source Type: research

Role of vericiguat in management of patients with heart failure with reduced ejection fraction after worsening episode
AbstractWorsening heart failure (HF) is a vulnerable period in which the patient has a markedly high risk of death or HF hospitalization (up to 10% and 30%, respectively, within the first weeks after episode). The prognosis of HF patients can be improved through a comprehensive approach that considers the different neurohormonal systems, with the early introduction and optimization of the quadruple therapy with sacubitril –valsartan, beta-blockers, mineralocorticoid receptor antagonists, and inhibitors. Despite that, there is a residual risk that is not targeted with these therapies. Currently, it is recognized that the ...
Source: ESC Heart Failure - December 30, 2023 Category: Cardiology Authors: Aleix Olivella, Luis Almenar ‐Bonet, Pedro Moliner, Emmanuel Coloma, Antoni Martínez‐Rubio, Marco Paz Bermejo, Ramon Boixeda, German Cediel, Ana Belén Méndez Fernández, Lorenzo Facila Rubio Tags: Review Source Type: research

Kidney and heart failure events are bidirectionally associated in patients with type 2 diabetes and cardiovascular disease
ConclusionsThese findings demonstrate a bidirectional inter-relationship between HHF and kidney events. Further exploration of this relationship and strategies to optimize the use of therapies to reduce both kidney and HF outcomes is warranted. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 29, 2023 Category: Cardiology Authors: Abhinav Sharma, Silvio E. Inzucchi, Jeffrey M. Testani, Anne Pernille Ofstad, David Fitchett, Michaela Mattheus, Subodh Verma, Faiez Zannad, Christoph Wanner, Bettina J. Kraus Tags: Original Article Source Type: research

Is ischaemic heart failure an autoimmune disease?
(Source: ESC Heart Failure)
Source: ESC Heart Failure - December 28, 2023 Category: Cardiology Authors: Susanne Sattler Tags: Editorial Source Type: research

The ratio of cytochrome c oxidase subunit 4 isoform 4I1 and 4I2 mRNA is changed in permanent atrial fibrillation
ConclusionsThis study describes a possible molecular correlate for the development of AF. Due to the known functional significance of COX 4I2, mitochondrial dysfunction can be assumed as a part of the pathogenesis of AF. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 27, 2023 Category: Cardiology Authors: Sebastian Vogt, Rabia Ramzan, Pia Cybulski, Annika Rhiel, Petra Weber, Volker Ruppert, Marc Irqsusi, Susanne Rohrbach, Bernd Niemann, Nikolas Mirow, Ardawan J. Rastan Tags: Original Article Source Type: research

Digital consults to optimize guideline ‐directed therapy: design of a pragmatic multicenter randomized controlled trial
ConclusionsThe ADMINISTER trial will offer the first randomized controlled data on GDMT prescription rates, time till full GDMT optimization, time spent on healthcare, quality of life, and patient and clinician satisfaction of the multifaceted patient- and clinician-targeted DC for GDMT optimization. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 26, 2023 Category: Cardiology Authors: Jelle P. Man, Marcel G.W. Dijkgraaf, M. Louis Handoko, Frederik J. de Lange, Michiel M. Winter, Marlies P. Schijven, Susan Stienen, Paola Meregalli, Wouter E.M. Kok, Dorianne I. Kuipers, Pim van der Harst, Maarten A.C. Koole, Steven A.J. Chamu Tags: Study Design Source Type: research

Body mass index, frailty, and outcomes in heart failure with preserved ejection fraction
ConclusionsBMI distribution and association between BMI and frailty risk were different between the two study populations. Frailty was associated with clinical adverse events and this association was consistent across different BMI categories in both studies. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 23, 2023 Category: Cardiology Authors: Wenjie Li, Zhiyan Wang, Chang Hua, Hao Zhang, Xinru Liu, Shiyue Zheng, Qiang Lv, Chao Jiang, Jianzeng Dong, Changsheng Ma, Xin Du Tags: Original Article Source Type: research

Characteristics of patients admitted with heart failure: Insights from the first Malaysian Heart Failure Registry
ConclusionsThe MY-HF Registry showed that the HF population in Malaysia is younger, predominantly male, and ischaemic-driven and has good prospects with hospitalization for optimization of treatment. These findings suggest a need to reassess current clinical practice and guide resource allocation to improve patient outcomes. (Source: ESC Heart Failure)
Source: ESC Heart Failure - December 22, 2023 Category: Cardiology Authors: Wan Azman Wan Ahmad, Abdul Kahar Abdul Ghapar, Hafisyatul Aiza Zainal Abidin, Dharmaraj Karthikesan, Noel Thomas Ross, Muhamad Ali S.K. Abdul Kader, Alexander Loch, Kauthaman Mahendran, Ahmad Wazi Ramli, Tiong Kiam Ong, Nor Hanim Mohd Amin, Chu Tags: Original Article Source Type: research