Hyperlactataemia is a marker of reduced exercise capacity in heart failure with preserved ejection fraction

ConclusionsHFpEF is associated with reduced exercise capacity secondary to both central and peripheral factors that alter oxygen utilization. This results in hyperlactataemia. In HFpEF, plasma lactate responses to exercise may be a marker of haemodynamic and cardiometabolic derangements and represent an important target for future potential therapies.

Source: ESC Heart Failure - May 3, 2024 Category: Cardiology Authors: Emilia Nan Tie, Emil Wolsk, Shane Nanayakkara, Donna Vizi, Justin Mariani, Jacob Eifer Moller, Christian Hassager, Finn Gustafsson, David M. Kaye Tags: Original Article Source Type: research