Filtered By:
Vaccination: Veterinary Vaccinations
This page shows you your search results in order of date. This is page number 3.
Order by Relevance | Date
Total 6987 results found since Jan 2013.
Burdening Perspectives and Treatment Modalities of Monkeypox: A Central Dogma
Infect Disord Drug Targets. 2023 Aug 25. doi: 10.2174/1871526523666230825164222. Online ahead of print.ABSTRACTThe monkeypox virus (MPXV), belonging to the genus Orthopoxvirus, is responsible for causing the zoonotic illness known as Monkeypox. The virus was initially identified during an outbreak at a Danish Zoo in 1958 and has since been found to infect various mammal species worldwide. While African squirrels and other rodents are believed to be the primary hosts, determining the natural host has proven challenging. While MPXV can be studied using different animal models in laboratory settings, understanding its natural...
Source: Infectious Disorders Drug Targets - September 12, 2023 Category: Infectious Diseases Authors: Shivang Dhoundiyal Md Aftab Alam Awaneet Kaur Sandesh Varshney Source Type: research
Evaluation of dynamics of immune responses and protective efficacy in piglets immunized with an inactivated porcine reproductive and respiratory syndrome vaccine candidate
In this study, we investigated the protective efficacy of an inactivated PRRS virus vaccine candidate and evaluated the differences in PRRSV specific anamnestic response in piglets when challenged with live PRRSV at two different intervals post-immunization. Six-week-old piglets were immunized intramuscularly with an inactivated, Montanide ISA-206 adjuvanted Indian PRRSV isolate, followed by a booster dose at 21 days post-immunization. Homologous live PRRS virus challenge was done on 60 and 180 days post-booster (dpb). We assessed humoral and cell-mediated immune responses at various intervals post-immunization and after c...
Source: Vaccine - September 9, 2023 Category: Allergy & Immunology Authors: Megha Katare Pandey Katherukamem Rajukumar Dhanapal Senthilkumar Subbiah Kombiah Fateh Singh Govindarajulu Venkatesh Manoj Kumar Sangeeta Shrivas Deepali Shrivastava Vijendra Pal Singh Aniket Sanyal Source Type: research
Full eradication of pre-clinical human papilloma virus-induced tumors by a lentiviral vaccine
EMBO Mol Med. 2023 Sep 7:e17723. doi: 10.15252/emmm.202317723. Online ahead of print.ABSTRACTHuman papillomavirus (HPV) infections are the cause of all cervical and numerous oropharyngeal and anogenital cancers. The currently available HPV vaccines, which induce neutralizing antibodies, have no therapeutic effect on established tumors. Here, we developed an immuno-oncotherapy against HPV-induced tumors based on a non-integrative lentiviral vector encoding detoxified forms of the Early E6 and E7 oncoproteins of HPV16 and 18 genotypes, namely, "Lenti-HPV-07". A single intramuscular injection of Lenti-HPV-07 into mice bearing...
Source: Molecular Medicine - September 7, 2023 Category: Molecular Biology Authors: La ëtitia Douguet Ingrid Fert Jodie Lopez Benjamin Vesin Fabien Le Chevalier Fanny Moncoq Pierre Authi é Trang-My Nguyen Amandine Noirat Fabien N évo Catherine Blanc Maryline Bourgine David Hardy Fran çois Anna Laleh Majlessi Pierre Charneau Source Type: research
Biotechnology in India - An Analysis of Biotechnology Industry Research Assistance Council (BIRAC)-Supported Projects
Chembiochem. 2023 Sep 5:e202300302. doi: 10.1002/cbic.202300302. Online ahead of print.ABSTRACTA comprehensive analysis of 2.165 projects funded by India's Department of Biotechnology since 2005 through private-public partnerships, and as of 2012 through the 'Biotechnology Industry Research Assistance Council (BIRAC)' until BIRAC's tenth anniversary end of March 2022 reveals details of the science and technology underpinning past and current biotechnology research and development projects in the country. They are led by human healthcare projects (74,9% overall), of which medical technology (58,7%) and therapeutics (24,5%) ...
Source: Chembiochem - September 5, 2023 Category: Biochemistry Authors: Edmond Differding Source Type: research
Immune system roles in pathogenesis, prognosis, control, and treatment of Toxoplasma gondii infection
Int Immunopharmacol. 2023 Sep 1;124(Pt A):110872. doi: 10.1016/j.intimp.2023.110872. Online ahead of print.ABSTRACTToxoplasma gondii is the protozoan causative agent of toxoplasmosis in humans and warm-blooded animals. Recent studies have illustrated that the immune system plays a pivotal role in the pathogenesis of toxoplasmosis by triggering immune cytokines like IL-12, TNF-α, and IFN-γ and immune cells like DCs, Th1, and Th17. On the other hand, some immune components can serve as prognosis markers of toxoplasmosis. In healthy people, the disease is often asymptomatic, but immunocompromised people and newborns may suf...
Source: International Immunopharmacology - September 3, 2023 Category: Allergy & Immunology Authors: Mohammad Mahdi Jafari Zahra Azimzadeh Tabrizi Mohammad Saaid Dayer Nazanin Atieh Kazemi-Sefat Mahshid Mohtashamifard Rahimeh Mohseni Atefeh Bagheri Saeed Bahadory Amir Karimipour-Saryazdi Fatemeh Ghaffarifar Source Type: research
Boosting of vaginal HSV-2-specific B and T cell responses by intravaginal therapeutic immunization results in diminished recurrent HSV-2 disease
In this study, a therapeutic vaccine given intravaginally resulted in significantly better protection against HSV-2 disease than immunization with the same vaccine by a conventional route. Immunization by the intravaginal route resulted in greater stimulation of vaginal-resident, virus-specific cells that produced antibody and produced immune molecules to rapidly clear virus.PMID:37655939 | DOI:10.1128/jvi.00669-23
Source: Herpes - September 1, 2023 Category: Infectious Diseases Authors: Nigel Bourne Celeste A Keith Aaron L Miller Richard B Pyles Gary Cohen Gregg N Milligan Source Type: research
Characterization of a gE/gI/TK gene-deleted pseudorabies virus variant expressing the Cap protein of porcine circovirus type 2d
Comp Immunol Microbiol Infect Dis. 2023 Aug 27;101:102054. doi: 10.1016/j.cimid.2023.102054. Online ahead of print.ABSTRACTPorcine circovirus type 2 (PCV2) plays a key role in the etiology of PCV2-associated disease (PCVAD), and its predominant strain is PCV2d which is not completely controlled by most commercially available vaccines against PCV2a strains. Pseudorabies (PR) caused by pseudorabies virus (PRV) variants re-emerged in Bartha-K61 vaccine-immunized swine herds in late 2011, which brought considerable losses to the global pig husbandry. Therefore, it is significantly important to develop a safe and effective vacc...
Source: Comparative immunology, microbiology and infectious diseases. - August 31, 2023 Category: Allergy & Immunology Authors: Rui-Qin Xu Lin-Qing Wang Hui-Hua Zheng Run-Bo Tian Lan-Lan Zheng Shi-Jie Ma Hong-Ying Chen Source Type: research
T cell control of SARS-CoV-2: When, which, and where?
Semin Immunol. 2023 Aug 29;70:101828. doi: 10.1016/j.smim.2023.101828. Online ahead of print.ABSTRACTEfficient immune protection against viruses such as SARS-CoV-2 requires the coordinated activity of innate immunity, B and T cells. Accumulating data point to a critical role for T cells not only in the clearance of established infection, but also for aborting viral replication independently of humoral immunity. Here we review the evidence supporting the contribution of antiviral T cells and consider which of their qualitative features favour efficient control of infection. We highlight how studies of SARS-CoV-2 and other c...
Source: Seminars in Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Mariana O Diniz Mala K Maini Leo Swadling Source Type: research
Characterization of a gE/gI/TK gene-deleted pseudorabies virus variant expressing the Cap protein of porcine circovirus type 2d
Comp Immunol Microbiol Infect Dis. 2023 Aug 27;101:102054. doi: 10.1016/j.cimid.2023.102054. Online ahead of print.ABSTRACTPorcine circovirus type 2 (PCV2) plays a key role in the etiology of PCV2-associated disease (PCVAD), and its predominant strain is PCV2d which is not completely controlled by most commercially available vaccines against PCV2a strains. Pseudorabies (PR) caused by pseudorabies virus (PRV) variants re-emerged in Bartha-K61 vaccine-immunized swine herds in late 2011, which brought considerable losses to the global pig husbandry. Therefore, it is significantly important to develop a safe and effective vacc...
Source: Comparative immunology, microbiology and infectious diseases. - August 31, 2023 Category: Allergy & Immunology Authors: Rui-Qin Xu Lin-Qing Wang Hui-Hua Zheng Run-Bo Tian Lan-Lan Zheng Shi-Jie Ma Hong-Ying Chen Source Type: research
Leptin/lipopolysaccharide-treated dendritic cell vaccine improved cellular immune responses in an animal model of breast cancer
CONCLUSION: Compared to the Leptin-treated mDC and LPS-treated mDC vaccines, the Leptin/LPS-treated mDC vaccine was more effective in inhibiting BC development and boosting immune responses against tumor.PMID:37647347 | DOI:10.1080/08923973.2023.2253989
Source: Cancer Control - August 30, 2023 Category: Cancer & Oncology Authors: Pedram Basirjafar Raziyeh Zandvakili Javad Masoumi Nahid Zainodini Zahra Taghipour Hossein Khorramdelazad Soheila Yousefi Tayyebeh Tavakoli Mahboobeh Vatanparast Sepehr Safdel Mahsa Gheitasi Fatemeh Ayoobi Bahar Naseri Abdollah Jafarzadeh Source Type: research
