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Vaccination: Veterinary Vaccinations
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Total 6987 results found since Jan 2013.
The future of pyrogenicity testing: Phasing out the rabbit pyrogen test. A meeting report
Biologicals. 2023 Aug 27;84:101702. doi: 10.1016/j.biologicals.2023.101702. Online ahead of print.ABSTRACTThe rabbit pyrogen test (RPT) was the benchmark for pyrogenicity testing, but scientific advancements have provided innovative and humane methods, such as the in vitro monocyte-activation test (MAT). However, transitioning from the RPT to the MAT has been challenging. The European Directorate for the Quality of Medicines & HealthCare, the Council of Europe, and the European Partnership for Alternative Approaches to Animal Testing jointly hosted an international conference entitled "The future of pyrogenicity testin...
Source: Biologicals : Journal of the International Association of Biological Standardization - August 29, 2023 Category: Biotechnology Authors: Gwena ël Cirefice Katrin Sch ütte Ingo Spreitzer Emmanuelle Charton Shahjahan Shaid Laura Viviani Michelle Rubbrecht Irene Manou Source Type: research
Detection of immune effects of the Mannheimia haemolytica gamma irradiated vaccine in sheep
In conclusion, the vaccinated sheep are protected by the elevated IgG titer and increased levels of IL-4 (Th-2 response) compared to the non-vaccinated sheep. Radiation technology can provide the opportunity for mass production of immunologically safe vaccines against animal and zoonotic diseases. Ethics Approval by the National Research Center Ethics Committee (Trial Registration Number (TRN) no 13,602,023, 13/5/2023) was obtained.PMID:37642819 | DOI:10.1007/s11259-023-10207-w
Source: Cell Research - August 29, 2023 Category: Cytology Authors: Sahar Ahmed Mohamed Abd El-Fatah Mahmoud Waleed Abdelgaber Nemr Eman Hussein Abdel-Rahman Asmaa El-Shershaby Ehab Ali Fouad Fatima Liaqat Viskam Wijewardana Source Type: research
The future of pyrogenicity testing: Phasing out the rabbit pyrogen test. A meeting report
Biologicals. 2023 Aug 27;84:101702. doi: 10.1016/j.biologicals.2023.101702. Online ahead of print.ABSTRACTThe rabbit pyrogen test (RPT) was the benchmark for pyrogenicity testing, but scientific advancements have provided innovative and humane methods, such as the in vitro monocyte-activation test (MAT). However, transitioning from the RPT to the MAT has been challenging. The European Directorate for the Quality of Medicines & HealthCare, the Council of Europe, and the European Partnership for Alternative Approaches to Animal Testing jointly hosted an international conference entitled "The future of pyrogenicity testin...
Source: Biologicals : Journal of the International Association of Biological Standardization - August 29, 2023 Category: Biotechnology Authors: Gwena ël Cirefice Katrin Sch ütte Ingo Spreitzer Emmanuelle Charton Shahjahan Shaid Laura Viviani Michelle Rubbrecht Irene Manou Source Type: research
Sick as a dog? The prevalence, politicization, and health policy consequences of canine vaccine hesitancy (CVH)
Vaccine. 2023 Aug 26:S0264-410X(23)01015-0. doi: 10.1016/j.vaccine.2023.08.059. Online ahead of print.ABSTRACTCanine vaccine hesitancy (CVH) can be thought about as dog owners' skepticism about the safety and efficacy of administering routine vaccinations to their dogs. CVH is problematic not only because it may inspire vaccine refusal - which may in turn facilitate infectious disease spread in both canine and human populations - but because it may contribute to veterinary care provider mental/physical health risks. In a nationally representative survey of US adults (N = 2200), we introduce a novel survey-based instrument ...
Source: Vaccine - August 28, 2023 Category: Allergy & Immunology Authors: Matt Motta Gabriella Motta Dominik Stecula Source Type: research
Plant Viruses as Adjuvants for Next-Generation Vaccines and Immunotherapy
Vaccines (Basel). 2023 Aug 16;11(8):1372. doi: 10.3390/vaccines11081372.ABSTRACTVaccines are the cornerstone of infectious disease control and prevention. The outbreak of SARS-CoV-2 has confirmed the urgent need for a new approach to the design of novel vaccines. Plant viruses and their derivatives are being used increasingly for the development of new medical and biotechnological applications, and this is reflected in a number of preclinical and clinical studies. Plant viruses have a unique combination of features (biosafety, low reactogenicity, inexpensiveness and ease of production, etc.), which determine their potentia...
Source: Cancer Control - August 26, 2023 Category: Cancer & Oncology Authors: Nikolai Nikitin Yuri Vasiliev Angelina Kovalenko Ekaterina Ryabchevskaya Olga Kondakova Ekaterina Evtushenko Olga Karpova Source Type: research
Bacterial ghost cell based bivalent candidate vaccine against Salmonella Typhi and Salmonella Paratyphi A: A prophylactic study in BALB/c mice
Vaccine. 2023 Aug 23:S0264-410X(23)00992-1. doi: 10.1016/j.vaccine.2023.08.049. Online ahead of print.ABSTRACTTyphoid and emerging paratyphoid fever are a severe enteric disease worldwide with high morbidity and mortality. Licensed typhoid vaccines are in the market, but no paratyphoid vaccine is currently available. In the present study we developed a bivalent vaccine against Salmonella Typhi and Paratyphi A using a bacterial ghost platform. Bacterial ghost cells (BGs) are bacteria-derived cell membranes without cytoplasmic contents that retain their cellular morphology, including all cell surface features. Furthermore, B...
Source: Vaccine - August 25, 2023 Category: Allergy & Immunology Authors: Prolay Halder Suhrid Maiti Soumalya Banerjee Sanjib Das Moumita Dutta Shanta Dutta Hemanta Koley Source Type: research
Development and characterization of a plant-derived norovirus-like particle vaccine
CONCLUSIONS: The plant-made NoVLP vaccine was safe and immunogenic in mice and rabbits. Multi-modal vaccination, combining oral and intramuscular administration could be considered for future clinical development to maximize systemic and mucosal immune responses.PMID:37625992 | DOI:10.1016/j.vaccine.2023.08.036
Source: Vaccine - August 25, 2023 Category: Allergy & Immunology Authors: Janna R Shapiro Guadalupe Andreani Charlotte Dub é M élanie Berubé Diane Bussi ère Manon M-J Couture Mich èle Dargis Hilary E Hendin Nathalie Landry Pierre-Olivier Lavoie St éphane Pillet Brian J Ward Marc-Andr é D'Aoust Sonia Tr épanier Source Type: research
Bacterial ghost cell based bivalent candidate vaccine against Salmonella Typhi and Salmonella Paratyphi A: A prophylactic study in BALB/c mice
Vaccine. 2023 Aug 23:S0264-410X(23)00992-1. doi: 10.1016/j.vaccine.2023.08.049. Online ahead of print.ABSTRACTTyphoid and emerging paratyphoid fever are a severe enteric disease worldwide with high morbidity and mortality. Licensed typhoid vaccines are in the market, but no paratyphoid vaccine is currently available. In the present study we developed a bivalent vaccine against Salmonella Typhi and Paratyphi A using a bacterial ghost platform. Bacterial ghost cells (BGs) are bacteria-derived cell membranes without cytoplasmic contents that retain their cellular morphology, including all cell surface features. Furthermore, B...
Source: Vaccine - August 25, 2023 Category: Allergy & Immunology Authors: Prolay Halder Suhrid Maiti Soumalya Banerjee Sanjib Das Moumita Dutta Shanta Dutta Hemanta Koley Source Type: research
Development and characterization of a plant-derived norovirus-like particle vaccine
CONCLUSIONS: The plant-made NoVLP vaccine was safe and immunogenic in mice and rabbits. Multi-modal vaccination, combining oral and intramuscular administration could be considered for future clinical development to maximize systemic and mucosal immune responses.PMID:37625992 | DOI:10.1016/j.vaccine.2023.08.036
Source: Vaccine - August 25, 2023 Category: Allergy & Immunology Authors: Janna R Shapiro Guadalupe Andreani Charlotte Dub é M élanie Berubé Diane Bussi ère Manon M-J Couture Mich èle Dargis Hilary E Hendin Nathalie Landry Pierre-Olivier Lavoie St éphane Pillet Brian J Ward Marc-Andr é D'Aoust Sonia Tr épanier Source Type: research
Diagnosis of a Rabbit Hemorrhagic Disease Virus 2 (RHDV2) and the Humoral Immune Protection Effect of VP60 Vaccine
This study suggested that the clinical application of VP60 may provide new ideas for preventing the spread of RHD2.PMID:37623236 | PMC:PMC10453004 | DOI:10.3390/cimb45080417
Source: Current Issues in Molecular Biology - August 25, 2023 Category: Molecular Biology Authors: Zhaoming Li Kaimin Song Yongzhen Du Zhuanglong Zhang Rupeng Fan Pimiao Zheng Jianzhu Liu Source Type: research
