Development and characterization of a plant-derived norovirus-like particle vaccine

CONCLUSIONS: The plant-made NoVLP vaccine was safe and immunogenic in mice and rabbits. Multi-modal vaccination, combining oral and intramuscular administration could be considered for future clinical development to maximize systemic and mucosal immune responses.PMID:37625992 | DOI:10.1016/j.vaccine.2023.08.036

Source: Vaccine - August 25, 2023 Category: Allergy & Immunology Authors: Janna R Shapiro Guadalupe Andreani Charlotte Dub é M élanie Berubé Diane Bussi ère Manon M-J Couture Mich èle Dargis Hilary E Hendin Nathalie Landry Pierre-Olivier Lavoie St éphane Pillet Brian J Ward Marc-Andr é D'Aoust Sonia Tr épanier Source Type: research