The Elevated Risk of Dementia in Parkinson's Disease Patients Associated with Metabolic Syndrome
Background: Metabolic syndrome (MetS) is prevalent in the general population, and recent findings have highlighted its role as an independent risk factor for cognitive impairment. The primary objective of this study is to explore the association between MetS and the risk of cognitive impairment within the Parkinson's disease (PD) population. (Source: Parkinsonism and Related Disorders)
Source: Parkinsonism and Related Disorders - May 1, 2024 Category: Neurology Authors: E. Kobak Tur, H.B. Kutlu, N. Sever, E. G özke Source Type: research
Obesity and metabolic syndrome in patients with heart failure with preserved ejection fraction: a cross-sectional analysis of the Veradigm Cardiology Registry
The proportion of heart failure patients with preserved ejection fraction has been rising over the past decades and has coincided with increases in the prevalence of obesity and metabolic syndrome. The relatio... (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - May 1, 2024 Category: Endocrinology Authors: Jay P Bae, Lee Kallenbach, David R Nelson, Kevin Lavelle, Jessamine P Winer-Jones, Machaon Bonafede and Masahiro Murakami Tags: Research Source Type: research
Metabolic Syndrome in people treated with Antipsychotics (RISKMet): A multimethod study protocol investigating genetic, behavioural, and environmental risk factors
ConclusionsThis project innovates MetS monitoring in psychiatry by using intensive digital phenotyping, identifying biochemical markers, assessing familial risks, and including genetically similar healthy controls. Study registration number
ISRCTN18419418 at www.isrctn.com. (Source: PLoS One)
Source: PLoS One - May 1, 2024 Category: Biomedical Science Authors: Giovanni de Girolamo Source Type: research
Associations between Hysterectomy and Metabolic Syndrome: The Multi-Ethnic Study of Atherosclerosis
Metabolic syndrome is linked to an increased risk of incident cardiovascular disease (CVD) and all-cause mortality. Notable associations exist between hysterectomy with bilateral salpingo-oophorectomy and metabolic syndrome. However, there is emerging evidence that even with ovarian conservation, hysterectomy may be independently associated with long-term CVD risk. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - May 1, 2024 Category: OBGYN Authors: Eric K. BRONI, Justin B. ECHOUFFO TCHEUGUI, Anna PALATNIK, Ernest M. GRAHAM, Ruth-Alma TURKSON-OCRAN, Yvonne COMMODORE-MENDAH, Chiadi E. NDUMELE, Erin D. MICHOS Tags: Original Research: Gynecology Source Type: research
Prevalence of metabolic syndrome among patients with hepatocellular carcinoma of different etiologies: a retrospective study
This study compared the prevalences of metabolic syndrome and of cardiac or kidney comorbidities among patients with hepatocellular carcinoma (HCC) associated with metabolic dysfunction-related fatty liver dis... (Source: Infectious Agents and Cancer)
Source: Infectious Agents and Cancer - May 1, 2024 Category: Cancer & Oncology Authors: Da-Long Yang, Shao-Ping Liu, Hong-Liang Wang, Jian-Rong Li, Jia-Yong Su, Min-Jun Li, Yu-Xian Teng, Zhu-Jian Deng, Zhong-Hai Li, Jian-Li Huang, Ping-Ping Guo, Liang Ma, Zhen-Zhen Li and Jian-Hong Zhong Tags: Research Source Type: research
Effect of the Healthy Dish Method to Reduce Waist Circumference in Teachers with Abdominal Obesity of a Peruvian University
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 30, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Protective effect of higher free thyroxine levels within the reference range on biliary tract cancer risk: a multivariable mendelian randomization and mediation analysis
CONCLUSION: The findings suggest that higher FT4-RR may have a protective effect against BTC, which is partially mediated by decreased risk of MetS and a reduction in WC. This study highlights the potential role of FT4 in the pathogenesis of BTC and underscores that MetS and WC may play mediation effects as two mediators in this process.PMID:38686204 | PMC:PMC11056546 | DOI:10.3389/fendo.2024.1379607 (Source: Cancer Control)
Source: Cancer Control - April 30, 2024 Category: Cancer & Oncology Authors: Yuxian Chen Hao Dong Baozhen Qu Xuezhen Ma LinLin Lu Source Type: research
Considerations of Care in Dementia of Schizophrenia
With an aging population, there is increasing number of persons with schizophrenia and dementia in the post-acute and long-term care settings. By eighty years of age, the prevalence of dementia diagnoses is 70.2% in persons with schizophrenia, compared to 11.3% in persons without. This high rate posits unique care considerations in the post-acute and long-term care settings. These include balancing medication management for mood and behavior stability while minimizing adverse side effects such as tardive dyskinesia and metabolic syndrome, and optimizing non-pharmacological interventions to enhance quality of life and safet...
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Sara Shu, Paul Takahashi Source Type: research
GSE263865 Inactivation of mitochondrial MUL1 E3 ubiquitin ligase deregulates mitophagy and prevents diet-induced obesity in mice
Contributors : Lucia Cilenti ; Jacopo Di Gregorio ; Rohit Mahar ; Camilla T Ambivero ; Muthu Periasamy ; Matthew E Merritt ; Antonis S ZervosSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusObesity is a growing epidemic affecting billions of people worldwide and a major risk factor for a multitude of chronic diseases and premature mortality. Accumulating evidence suggests that mitochondria have a profound role in diet-induced obesity and the associated metabolic changes, but the molecular mechanisms linking mitochondria to obesity remain poorly understood. Our studies have identif...
Source: GEO: Gene Expression Omnibus - April 30, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
Recipient microbiome-related features predicting metabolic improvement following fecal microbiota transplantation in adults with severe obesity and metabolic syndrome: a secondary analysis of a phase 2 clinical trial
Volume 16, Issue 1, January-December 2024 . (Source: Gut Microbes)
Source: Gut Microbes - April 30, 2024 Category: Microbiology Authors: Zhengxiao ZhangValentin MocanuEdward C. DeehanNaomi HotteYuanyuan ZhuShanshan WeiDina H. KaoShahzeer KarmaliDaniel W. BirchJens WalterKaren L. Madsena College of Ocean Food and Biological Engineering, Fujian Provincial Engineering Technology Research Cent Source Type: research
The association between dietary patterns and metabolic syndrome among Iranian adults, a cross-sectional population-based study (findings from Bandare-Kong non-communicable disease cohort study)
Metabolic syndrome is a cluster of metabolic disorders increasing the risk of cardiovascular disease and diabetes. Dietary patterns are supposed to be important and controllable factors in developing metabolic... (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - April 30, 2024 Category: Endocrinology Authors: Masoumeh Kheirandish, Farideh Dastsouz, Abnoos Azarbad, Mohammad Ali Mohsenpour, Gholamali Javdan, Farkhondeh Razmpour, Seyed Hossein Davoodi, Nahid Ramezani-Jolfaie and Mohammad Mohammadi Tags: Research Source Type: research
Cost-effectiveness of semaglutide 2.4 mg in chronic weight management in Portugal
Obesity and overweight are a significant public health concern. Subcutaneous semaglutide 2.4 mg injection is a glucagon-like peptide-1 (GLP-1) analogue approved by the European Medicines Agency as an adjunct t... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - April 30, 2024 Category: Endocrinology Authors: Lu ís Silva Miguel, Mariana Soares, Anamaria Olivieri, Filipa Sampaio, Mark Lamotte, Suramya Shukla, Vasco Conde, Paula Freitas, João Costa and Margarida Borges Tags: Research Source Type: research
Recipient microbiome-related features predicting metabolic improvement following fecal microbiota transplantation in adults with severe obesity and metabolic syndrome: a secondary analysis of a phase 2 clinical trial
Volume 16, Issue 1, January-December 2024 . (Source: Gut Microbes)
Source: Gut Microbes - April 30, 2024 Category: Microbiology Authors: Zhengxiao ZhangValentin MocanuEdward C. DeehanNaomi HotteYuanyuan ZhuShanshan WeiDina H. KaoShahzeer KarmaliDaniel W. BirchJens WalterKaren L. Madsena College of Ocean Food and Biological Engineering, Fujian Provincial Engineering Technology Research Cent Source Type: research
397. Assessing the Potential Role of Platelets in Metabolic Syndrome-Related Cognitive Impairment in Veterans With Schizophrenia
Schizophrenia is associated with progressive cognitive decline. Metabolic syndrome (MetS) —characterized by truncal obesity, insulin resistance, dyslipidemia and hypertension—is highly prevalent in individuals with schizophrenia and has been associated with cognitive impairment, but the underlying mechanism is not known. We sought to determine whether Veterans with schizophrenia como rbid with MetS (relative to those without MetS) have: 1) worse cognition; 2) higher level of platelet activation, and 3) whether platelet activation is negatively correlated with cognitive function. (Source: Biological Psychiatry)
Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Olaoluwa Okusaga, Vinod Vijayan, Rolando Rumbaut Source Type: research
No Association Between AGT Gene Polymorphisms with Hypertension in a South African Population
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 29, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
